Histology (Skin) - Part 2

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Histology (Skin) - Part 2

  1. 1. (sweat glands(eccrine Myoepithelial cell Sweat duct Sweat gland Secretory cell
  2. 2. ECCRINE AND APOCRINE GANDS
  3. 3. Skin Glands
  4. 4. Structures of skin: hair follicle  Invagination of epidermis  Hair contains keratin and melanin  Dermal papilla  Connective tissue invagination into bulb, has capillary network  Matrix  Germinative layer adjacent to dermal papilla  Also contains melanocytes  Sebaceous gland  Secretion empties into hair follicle(dermal papilla)  Arrector pili muscle bulb  Smooth muscle, inserts on hair follicle and base of epidermis
  5. 5. THE HAIR
  6. 6. The hair is formed of Shaft: medulla, cortex and cuticle The hair follicle is formed of : Inner root sheath formed of: Cuticle ,Huxleys layer,Henles layer Outer root sheath: identical with Malpighian Layer of epidermis Connective tissue sheath
  7. 7. Structures of skin: hairfollicle Arrector pili muscle Sebaceous gland Dermal papilla
  8. 8. Thick skin vs thin skin Thick skin  Palms and soles  Thicker epidermis  Hairless ,more sweat  glands Thin skin  Everywhere else  Thinner epidermis  Hair, sebaceous  And sweat glands
  9. 9. FINGER PRINTS
  10. 10. THE PANCREAS
  11. 11. The Pancreas
  12. 12. Exocrine part Stroma : thin C.T capsule &trabeculae. Parencaima : pancreatic acini ,lined with Pyramidal cells with apical acidophilic zymogen granules and basal basophilic striation. Secrete digestive enzymes via duct system starting by intercalated ducts.
  13. 13. Pancreatic acinus
  14. 14. PancreasIntercalated ducts&Centroacinar cells
  15. 15. Endocrine Pancreas
  16. 16. ISLETS OF LANGERHANS Non capsolated anastomosing cords of cells separated by blood sinusoids Alpha-cells 15-20um, prepheral Secrete glucacone 20 % stain pink with Gomori Beta –cells 10-15um, central in position 60-75%, Stain blue with Gomori stain Secrete insulin
  17. 17.  Delta cells 2% Secrete somatostatine which supresses A,B cells and growth hormone secretion PP cells 2% secrete pancreatic polypeptide which is involved in protein and carbohydrate metabolism. Ganglion cells Involved in nervous control of islet functions.
  18. 18. http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Liver/Images/pan20he.jpg
  19. 19. Islets- glucagon
  20. 20. Islet- insulin
  21. 21. Islet-somatostatin
  22. 22. Cells of islets of langerhansβ Immunohistoch emical stain δα
  23. 23. Islet of langerhans
  24. 24. Pancreas
  25. 25. Pancreas
  26. 26. Quiz? ? DO YOU KNOW
  27. 27. 2. Where are the stem cells of theepidermis located? A. B. C. D. E.
  28. 28. 2. What is the name of the layerslabeled (A) &(B) and (C)? A. B. C. D. E.
  29. 29. The structure at the .3:pointer  A. is involved in touch sensation  B. contains unmyelinated nerve endings  C. both A and B  D. is involved in vibratory sensation  E. none of the above
  30. 30. Thank you

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