Immunology xiii autoimmunity

Immune tolerance, autoimmune diseases

Immune tolerance ,[object Object],[object Object],[object Object]

Positive selection in the thymus

Negative selection in the thymus

Immune tolerance ,[object Object],[object Object],[object Object],[object Object],[object Object]

Regulatory T cells ,[object Object],[object Object]

Acquired immune tolerance ,[object Object],[object Object],[object Object]

Mechanisms of breakage of immune tolerance ,[object Object],[object Object],[object Object],[object Object],[object Object]

Systemic lupus erythematosus Rheumatoid arthritis Sjogren’s syndrome Polymyositis Dermatomyositis Scleroderma (progressive systemic sclerosis) Systemic autoimmune diseases

SLE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Systemic lupus etythematodes (SLE) ,[object Object],[object Object],[object Object],[object Object]

Systemic lupus erythematodes Clinical presentation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Systemic lupus etythematodes ,[object Object]

Autoantibodies in SLE - 1 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Positivity of antinuclear antibodies (ANA, ANF) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Endocrine system Autoimmune (Hasimoto’s) thyroiditis Hyperthyroidism (Graves’ disease; thyrotoxicosis) Type I diabetes mellitus (insulin-dependent or juvenile diabetes) Autoimmune adrenal insufficiency (Addison’s disease) Autoimmune oophritis Hermatopoietic system Autoimmune hemolytic anemia autoimmune thrombocytopenia Autoimmune neutropenia Neuromuscular system Myasthenia gravis Autoimmune polyneuritis Multiple sclerosis Skin Pemphigus and other bullous diseases Cardiopulmonary System Rheumatic carditis Postcardiotomy syndrome (Dressler’s syndrome) Gastrointestina tract Atrophic gastritis Crohn´s disease Ulcerous colitis Autoimmune hepatitis Organ-specific autoimmune diseases

Anti- parietal cells antibodies

Pernicious anemia ,[object Object],[object Object],[object Object],[object Object]

Anti-receptor antibodies ,[object Object],[object Object],[object Object],[object Object]

Treatment of autoimmune diseases ,[object Object],[object Object],[object Object],[object Object]

Systemic Immunosuppression ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Imunostimulatory drugs ,[object Object],[object Object],[object Object],[object Object]

Immunology xiii autoimmunity

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Immunology xiii autoimmunity