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Searching PubMed® TTUHSC  Libraries presents Rev. 01/19/10 PE
To begin...
Mouse-over Databases
Click PubMed
PubMed Home Page
Searching PubMed
PSmithLibrary Click MeSH Database
MeSH Database Terms in the database are called M edical  S ubject  H eadings or  MeSH . is a “controlled vocabulary list” of more than 25,000   subject headings. 10-15   MeSH   are assigned to each article in  PubMed . The  MeSH  index   of   10-15   subject headings is like a keyword abstract of the article. MeSH   are updated annually in December.
A  Anatomy C  Diseases B  Organisms D  Chemicals & Drugs D1  Inorganic Chemicals D2  Organic Chemicals D3  Heterocyclic Compounds D4  Polycyclic Compounds D5  Macromolecular Substances D6  Hormones, Hormone Substitutes, &  Hormone Antagonists  D8  Enzymes, & Coenzymes D9 Carbohydrates D10 Lipids D12 Amino Acids, Peptides, & Proteins D13 Nucleic Acids, Nucleotides, & Nucleosides D20 Complex Mixtures D23 Biologic Factors D25 Biomedical and Dental Materials D26 Pharmaceutical Preparations D27 Chemical Actions and Uses C1 Bacterial Infections & Mycoses C2 Virus Diseases C3 Parasitic Diseases C4 Neoplasms C5 Musculoskeletal Diseases C6 Digestive System Diseases C7 Stomatognathic Diseases C8 Respiratory Tract Diseases C9 Otorhinolaryngologic Diseases C10 Nervous System Diseases C11 Eye Diseases C12 Male Urogenital Diseases C13 Female Urogenital Diseases & Pregnancy Complications C14 Cardiovascular Diseases C15 Hemic & Lymphatic Diseases C16 Congenital, Hereditary, & Neonatal  Diseases & Abnormalities C17 Skin & Connective Tissue Diseases C18 Nutritional & Metabolic Diseases C19 Endocrine System Diseases C20 Immune System Diseases C21 Disorders of Environmental Origin C22 Animal Diseases C23 Pathologic Conditions, Signs, and  Symptoms A1  Body Regions A2  Musculoskeletal    System A3  Digestive System A4  Respiratory System A5  Urogenital System A6  Endocrine System A7  Cardiovascular    System A8  Nervous System A9  Sense Organs A10 Tissues A11 Cells A12 Fluids and Secretions A13 Animal Structures A14 Stomatognathic System A15 Hemic and Immune Systems A16 Embryonic Structures A 17 Integumentary System B1  Animals B2  Algae B3  Bacteria B4  Viruses B5  Fungi  B6  Plants B7  Archaea B8 Mesomycetozoea  Frequently Used Mesh Categories – 2011
Other Categories Include : Analytical, Diagnostic, & Therapeutic Techniques & Equipment Psychiatry and Psychology Phenomena and Processes: Physical, Chemical, Metabolic, Cell, Genetic, Microbiological, Physiological, & Mathematical Concepts Disciplines and Occupations Technology, Industry, Agriculture Anthropology, Education, Sociology & Social Phenomena Publication Characteristics Information Science Named Groups Health Care Geographic Locations
Create a Search Strategy Plan Identify the question and key concepts: alanine or threonine in the  genetics of neoplasms Write the search program using  keywords and subject headings.
(Note: If there is a Boolean OR relationship, start with the “ OR” statement first.) Enter   and click  a a Search alanine
Term Definitions
✔ 1) Check the box next to the MeSH heading a 2) Then click Add to search builder
The first  term is in the search program “box” MeSH
(Note: If there is a Boolean OR relationship, start with the “ OR” statement first.) Enter   and click  a a threonine Search
✔ 1) Check the box next to the MeSH heading a 3) Then click Add to search builder 2) Select  OR
The second  term is in the search program “box” MeSH
Boolean Logic - OR threonine OR alanine
a a Enter and click  neoplasms Search
Click the underlined term
Scroll screen down to view…
terms arranged in tree structure hierarchy MeSH  Terms are listed from broadest to narrowest. If  Abdominal Neoplasms yields zero results, try using a broader term:  Neoplasms by Site .
terms arranged in tree structure hierarchy MeSH  Scroll screen back up
Sub-headings   narrow the “meaning” of a articles   under the  MeSH   term:  Neoplasms . M   They are a “subset” of  all  the  MeSH  term.
embryology physiology abnormalities enzymology physiopathology administrations & dosage epidemiology poisoning adverse effects ethics prevention & control agonists ethnology   psychology analogs & derivatives etiology radiation effects  analysis radiography anatomy & histology genetics radionuclide imaging antagonists & inhibitors radiotherapy biosynthesis growth & development rehabilitation blood history   secondary blood supply immunology   secretion cerebrospinal fluid injuries standards chemical synthesis  innervation statistics & numerical data  chemically induced  instrumentation supply & distribution chemistry isolation & purification  surgery classification legislation & jurisprudence  therapeutic use complications manpower  therapy congenital metabolism   toxicity contraindications methods   transmission cytology microbiology transplantation  deficiency mortality trends diagnosis nursing ultrasonography diagnostic use organization & administration  ultrastructure diet therapy parasitology urine  drug effects pathogenicity utilization  drug therapy pathology veterinary economics pharmacokinetics virology education pharmacology 83 SUBHEADINGS:
✔ 1) Check the box next to the subheading a 3) Then click Add to search builder 2) Select  AND
Boolean Logic - AND and neoplasms/ genetics alanine OR threonine
The search program is complete. Click Search PubMed
Search Results
PubMed identifies   220 articles
Click Limits
Limits include: a A Language Human or Animal Publication Date Gender Type of Article Subsets Ages
✔ ✔ Click Search In this search, only articles that are human studies and written in English are included.
Results are reduced From 220 to 196
AA Scroll to article #9
X Select  article(s). X AA Scroll back up
Click   Display Settings
then click Select Abstract, change to Pub Date to sort to most recent articles appearing first, Apply
Click  for MeSH terms . +
AND OR threonine MeSH Database searches  only the   MeSH   terms   for:  neoplasms/genetics alanine
You may want to  write a new search program using: Look at subject headings  in the MeSH Terms Index for additional terms. Polymorphism, Genetic
Links from this record to NCBI databases. Click Gene.
Entrez Gene record Click the back button.
File   to save citations to a file on your computer or Clipboard   to temporarily store selected citations or  E-mail  to send citations to self or colleague . Click  Send to:   and select
… or click icon for full text .
Linking to Full-Text Articles in   Electronic Journals
Enter the  eRaider username and password  assigned to you by Information Services. When Searching from Home:
Click  PDF
Full Text Article  Close Article
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PubMed's MeSH Database

  • 1. Searching PubMed® TTUHSC Libraries presents Rev. 01/19/10 PE
  • 8. MeSH Database Terms in the database are called M edical S ubject H eadings or MeSH . is a “controlled vocabulary list” of more than 25,000 subject headings. 10-15 MeSH are assigned to each article in PubMed . The MeSH index of 10-15 subject headings is like a keyword abstract of the article. MeSH are updated annually in December.
  • 9. A Anatomy C Diseases B Organisms D Chemicals & Drugs D1 Inorganic Chemicals D2 Organic Chemicals D3 Heterocyclic Compounds D4 Polycyclic Compounds D5 Macromolecular Substances D6 Hormones, Hormone Substitutes, & Hormone Antagonists D8 Enzymes, & Coenzymes D9 Carbohydrates D10 Lipids D12 Amino Acids, Peptides, & Proteins D13 Nucleic Acids, Nucleotides, & Nucleosides D20 Complex Mixtures D23 Biologic Factors D25 Biomedical and Dental Materials D26 Pharmaceutical Preparations D27 Chemical Actions and Uses C1 Bacterial Infections & Mycoses C2 Virus Diseases C3 Parasitic Diseases C4 Neoplasms C5 Musculoskeletal Diseases C6 Digestive System Diseases C7 Stomatognathic Diseases C8 Respiratory Tract Diseases C9 Otorhinolaryngologic Diseases C10 Nervous System Diseases C11 Eye Diseases C12 Male Urogenital Diseases C13 Female Urogenital Diseases & Pregnancy Complications C14 Cardiovascular Diseases C15 Hemic & Lymphatic Diseases C16 Congenital, Hereditary, & Neonatal Diseases & Abnormalities C17 Skin & Connective Tissue Diseases C18 Nutritional & Metabolic Diseases C19 Endocrine System Diseases C20 Immune System Diseases C21 Disorders of Environmental Origin C22 Animal Diseases C23 Pathologic Conditions, Signs, and Symptoms A1 Body Regions A2 Musculoskeletal System A3 Digestive System A4 Respiratory System A5 Urogenital System A6 Endocrine System A7 Cardiovascular System A8 Nervous System A9 Sense Organs A10 Tissues A11 Cells A12 Fluids and Secretions A13 Animal Structures A14 Stomatognathic System A15 Hemic and Immune Systems A16 Embryonic Structures A 17 Integumentary System B1 Animals B2 Algae B3 Bacteria B4 Viruses B5 Fungi B6 Plants B7 Archaea B8 Mesomycetozoea Frequently Used Mesh Categories – 2011
  • 10. Other Categories Include : Analytical, Diagnostic, & Therapeutic Techniques & Equipment Psychiatry and Psychology Phenomena and Processes: Physical, Chemical, Metabolic, Cell, Genetic, Microbiological, Physiological, & Mathematical Concepts Disciplines and Occupations Technology, Industry, Agriculture Anthropology, Education, Sociology & Social Phenomena Publication Characteristics Information Science Named Groups Health Care Geographic Locations
  • 11. Create a Search Strategy Plan Identify the question and key concepts: alanine or threonine in the genetics of neoplasms Write the search program using keywords and subject headings.
  • 12. (Note: If there is a Boolean OR relationship, start with the “ OR” statement first.) Enter and click a a Search alanine
  • 14. ✔ 1) Check the box next to the MeSH heading a 2) Then click Add to search builder
  • 15. The first term is in the search program “box” MeSH
  • 16. (Note: If there is a Boolean OR relationship, start with the “ OR” statement first.) Enter and click a a threonine Search
  • 17. ✔ 1) Check the box next to the MeSH heading a 3) Then click Add to search builder 2) Select OR
  • 18. The second term is in the search program “box” MeSH
  • 19. Boolean Logic - OR threonine OR alanine
  • 20. a a Enter and click neoplasms Search
  • 22. Scroll screen down to view…
  • 23. terms arranged in tree structure hierarchy MeSH Terms are listed from broadest to narrowest. If Abdominal Neoplasms yields zero results, try using a broader term: Neoplasms by Site .
  • 24. terms arranged in tree structure hierarchy MeSH Scroll screen back up
  • 25. Sub-headings narrow the “meaning” of a articles under the MeSH term: Neoplasms . M They are a “subset” of all the MeSH term.
  • 26. embryology physiology abnormalities enzymology physiopathology administrations & dosage epidemiology poisoning adverse effects ethics prevention & control agonists ethnology psychology analogs & derivatives etiology radiation effects analysis radiography anatomy & histology genetics radionuclide imaging antagonists & inhibitors radiotherapy biosynthesis growth & development rehabilitation blood history secondary blood supply immunology secretion cerebrospinal fluid injuries standards chemical synthesis innervation statistics & numerical data chemically induced instrumentation supply & distribution chemistry isolation & purification surgery classification legislation & jurisprudence therapeutic use complications manpower therapy congenital metabolism toxicity contraindications methods transmission cytology microbiology transplantation deficiency mortality trends diagnosis nursing ultrasonography diagnostic use organization & administration ultrastructure diet therapy parasitology urine drug effects pathogenicity utilization drug therapy pathology veterinary economics pharmacokinetics virology education pharmacology 83 SUBHEADINGS:
  • 27. ✔ 1) Check the box next to the subheading a 3) Then click Add to search builder 2) Select AND
  • 28. Boolean Logic - AND and neoplasms/ genetics alanine OR threonine
  • 29. The search program is complete. Click Search PubMed
  • 31. PubMed identifies 220 articles
  • 33. Limits include: a A Language Human or Animal Publication Date Gender Type of Article Subsets Ages
  • 34. ✔ ✔ Click Search In this search, only articles that are human studies and written in English are included.
  • 35. Results are reduced From 220 to 196
  • 36. AA Scroll to article #9
  • 37. X Select article(s). X AA Scroll back up
  • 38. Click Display Settings
  • 39. then click Select Abstract, change to Pub Date to sort to most recent articles appearing first, Apply
  • 40. Click for MeSH terms . +
  • 41. AND OR threonine MeSH Database searches only the MeSH terms for: neoplasms/genetics alanine
  • 42. You may want to write a new search program using: Look at subject headings in the MeSH Terms Index for additional terms. Polymorphism, Genetic
  • 43. Links from this record to NCBI databases. Click Gene.
  • 44. Entrez Gene record Click the back button.
  • 45. File to save citations to a file on your computer or Clipboard to temporarily store selected citations or E-mail to send citations to self or colleague . Click Send to: and select
  • 46. … or click icon for full text .
  • 47. Linking to Full-Text Articles in Electronic Journals
  • 48. Enter the eRaider username and password assigned to you by Information Services. When Searching from Home:
  • 50. Full Text Article Close Article
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