Purifier Logic Class II Biological Safety Cabinets Presentation
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Purifier Logic Class II Biological Safety Cabinets Presentation

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Purifier Logic Class II Biological Safety Cabinets Presentation Purifier Logic Class II Biological Safety Cabinets Presentation Presentation Transcript

  • Purifier® Logic® Class II Biological Safety Cabinet
  • COPYRIGHT NOTICE The material included in this presentation is copyright of Labconco Corporation. Reproduction or use of the slides is not permitted without express permission from Labconco Corporation.
  • Fume Hood or Biological Safety Cabinet? Fume Hoods - Enclosures that capture, contain and remove chemical fumes and vapors. Biological Safety Cabinets - Enclosures that capture, contain and remove biohazardous aerosols.
  • Purifier® Logic® Class II Biological Safety Cabinet Optional 254 nm UV lamp Contain-Air Negative Pressure Channel Bright, glare-free fluorescent lighting Innovative LCD information center display Fully-closing, counterbalanced tempered safety glass sash Easy-to-clean touchpad controls Large 21.7” sash opening height Reserve-Air Secondary Airflow Slots Leak-tight Type 304 stainless steel Curved stainless steel inlet grille liner Type 304 stainless steel dished Accessory Base Stand (sold work surface with lift out knobs separately)
  • Purifier® Logic® Biosafety Cabinet Being Green is being responsible Labconco is a member of the United States Green Building Council (USGBC). Three Labconco product lines contribute to LEED® points: Purifier® Logic® Biosafety Cabinets FlaskScrubber® and SteamScrubber® Laboratory Glassware Washers Protector® XStream® Laboratory Fume Hoods
  • Purifier® Logic® Motor Intelligence Built In New motor technology • Electronically Commutated Motor (ECM) • Over 3 million in use Customer Advantages • Quieter • Cooler Operation • Energy savings of 60% • More reliable for correct airflow maintenance • Continuously outputs information to be displayed and triggers alarms when out of parameters
  • Purifier® Logic® Biosafety Cabinet Why is it cooler and quieter? • The ECM is more energy efficient ~ less energy is wasted as heat
  • Purifier® Logic® Biosafety Cabinet Intelligence Built In How do we know it is running okay? • The motor is programmed to maintain constant airflow as the filter loads, no sensors needed How does that work? • Each BSC is tested at various airflows and volumes • Software uses data to generate a motor-blower curve programmed into each motor • The motor remembers the speeds and torques required as filter pressures change
  • Purifier® Logic® Biosafety Cabinet How do we know the ECM is running correctly? • The ECM continuously outputs information to be displayed and triggers an airflow alert when the motor speed changes suddenly How do we know to change the filters? • Motor initial and maximum speeds are calculated and filter life remaining is figured
  • Purifier® Logic® Biosafety Cabinet The conventional motor used in biosafety cabinets is a Permanent Split Capacitor (PSC) motor. It is known as an induction motor. Labconco Delta (pre-2008) NuAire LabGard ESCO Labculture ECM PSC motor Permanent magnet on the rotor Magnetic field must be induced More efficient Generates a lot of waste heat Performance feedback No feedback
  • Purifier® Logic® Biosafety Cabinet How the Logic ECM is better Heat is the #1 killer of motors because it reduces the life of the bearing/bushing lubricant. Because the PSC runs hotter, it will fail faster than an ECM. The ECM uses hardened ball bearings on the rotor-most PSC motors use simple bushings. Cooler operation and bearings in the ECM means a much longer lifespan for the ECM…rated to 50,000 hours.
  • Purifier® Logic® Biosafety Cabinet Logic ECM energy comparison The ECM saves significant energy compared to other motor technologies used in biosafety cabinets. Power Consumption (Watts)* ECM PSC 3-Phase 4' BSC** 290 582 480 6' BSC** 490 1440 804 *At 120V ** 10" sash height
  • Purifier® Logic® Biosafety Cabinet LCD Information Center Line-of-sight on inside wall Filter status Cabinet status Error messages Icons indicate features on/off Interval or “stop watch” timer Fluorescent/UV Hour meter with alarm
  • Purifier® Logic® Biosafety Cabinet LCD Information Center Status area • “OK” • “Sash is too high” • “Airflow Alert” • “System Error” Data area • Displays the filter remaining, inflow and downflow velocities Icon Area • Displays icons of active features
  • Purifier® Logic® Biosafety Cabinet Icons Normal blower operation Night-Smart blower operation Fluorescent light UV light Timer Security Lock Mute
  • Purifier® Logic® Biosafety Cabinet Simple interior design • Easy to clean • Electrical duplex up and out of work surface area • Accessories keep work area uncluttered • Improved lighting Dual fluorescent lamps instead of one
  • Purifier® Logic® Biosafety Cabinet Simple interior design • No thumb screws • Lifting knobs on both ends • Work surface support to assist for removal • Towel catch/Pre-filter retained Towel Catch without fasteners • Smooth work surface Work Surface Support
  • Purifier Logic® Biosafety Cabinet Sash Changes • Viewing height increased 1.75" • Angled sash with no sash handle across the bottom edge for better viewing • Formed handles attached to sash for easy gripping
  • Purifier® Logic® Biosafety Cabinet Dimensions Lower exterior height • Approx. 3/4" lower overall Greater interior height • Approx. 2" taller in the front Increased viewing height
  • Purifier® Logic® Accessories Improved Filter Options • Accept ULPA filters • Optional pre-filters • Optional carbon post-filters on 4' - 6' models Stick-on Foam Stick- Prefilter Carbon Filtered Exhaust
  • Purifier® Logic® Biosafety Cabinets Accessories Telescoping Base Stand Adjusts in 1 inch increments from 27" to 34.5" NSF-listed and ADA-compliant Durable epoxy coating Available with fixed leveling feet or toe- locking polyurethane casters Seismic models available
  • Purifier® Logic® Biosafety Cabinets Accessories Hydraulic Lift Base Stand Built-in electric or manual hydraulic lift Height is adjustable from 25.5" to 33.5" Supports loads up to 1000 pounds Available in 3', 4', 5' and 6' widths NSF-listed and ADA-compliant Left: Manual Hydraulic Lift Base Stand is shown with Caster Kit installed.
  • Purifier® Logic® Biosafety Cabinets Accessories Optional Wire Shelves (stainless steel snap-in) Optional Cord/Tubing management hooks
  • Purifier® Logic® Biosafety Cabinet Accessories Stainless Steel Turntable Vacuum Aspiration Pump
  • Purifier® Logic® Biosafety Cabinet Accessories Airflow Sensor Kit (not shown) • Kit allows for installation of airflow sensors in the field • Optional sensor can be factory installed • Recognizes sensor and displays inflow (after calibration) IV Bar supports intravenous solution bottles and bags UV Light Kits include one 254 nm UV lamp Service Fixture
  • Purifier® Logic® Biosafety Cabinet Accessories Logic® Cart Provides convenient supply storage Fits easily under the Purifier Logic Class II Safety Cabinets mounted on Base Stand 2" casters provide mobility
  • Purifier® Logic® Biosafety Cabinet Accessories Ergonomic Chair • 6-way articulating seat • Removable armrests Adjustable Footrest • Elevate feet and permits angle repositioning while in use
  • Purifier® Logic® Biosafety Cabinet Accessories Support Shelves • Provide work surface to support remote equipment • Epoxy-coated steel shelf mounts to left-side frame of base stand Laptop Computer Arm • Securely supports laptop computer • Articulating arm raises, lowers and pivots to a steady position
  • Purifier® Logic® Agency Approvals NSF Standard 49 Listed • With carbon post-filter and pre-filter installed • With accessory shelves, hooks, and IV bar in place ETL, ETL-C and CE mark Accessory Base stand tip tested by NSF
  • Working in Biological Safety Cabinets Planning Thoroughly understand procedures and equipment required before beginning work and arrange for minimal disruptions Have disinfectant and spill cleanup materials prepared
  • Working in Biological Safety Cabinets Start Up Turn off UV light, open sash to its proper height, and turn on cabinet lights and blower Check grille for obstructions and let the cabinet operate for 5 minutes Wash hands and arms thoroughly with disinfectant soap; wear a long sleeved lab coat and gloves Use eye protection
  • Working in Biological Safety Cabinets Wipe-Down Wipe down all interior surfaces of the work area with a solution of 70% ethanol or other suitable disinfectant
  • Working in Biological Safety Cabinets Loading Load only the materials needed. Do not overload the cabinet or obstruct the grille. Keep large objects separated. Lower the sash until it is in its proper position. Allow the unit to operate for 2 to 3 minutes to purge any airborne contaminants.
  • Working in Biological Safety Cabinets Work Techniques Keep materials at least 4" inside the sash opening and perform all contaminated operations as far to the rear of the work area as possible. Segregate clean and contaminated materials. Arrange materials to minimize movement of contaminated materials into clean areas. Keep all contaminated material in the rear of the work area. Avoid excessive movement of arms or materials through the front opening during operation.
  • Working in Biological Safety Cabinets Work Techniques Use proper aseptic technique. Avoid techniques that disrupt airflow patterns in the cabinet, such as an open flame. If there is a spill or splatter during use, all objects must be decontaminated before removal. Thoroughly disinfect the interior surfaces of the cabinet while it is still in operation.
  • Working in Biological Safety Cabinets Final Purging After completing work, allow the cabinet to operate for 2 to 3 minutes undisturbed to purge airborne contaminants from the work area.
  • Working in Biological Safety Cabinets Wipe-Down Periodically lift the work surface and clean underneath it. Clean the towel catch. Dispose of rubber gloves and have lab coat properly laundered. Wash arms and hands thoroughly with germicidal soap. Wipe down all interior surfaces of the work area with a suitable disinfectant.
  • Working in Biological Safety Cabinets Shutdown Turn off the fluorescent light and cabinet blower, close the sash and turn on the UV light if appropriate.
  • Cabinet Maintenance User Performed Maintenance Replace fluorescent and UV lamps annually Reset circuit breakers Airflow smoke test Establish a smoke split • Mark work surface where smoke split occurs • May use smoke stick or dry ice to determine where split occurs • User should work behind smoke split
  • Cabinet Maintenance Certification A validation of cabinet integrity and performance Performed by a qualified independent technician Performed when the cabinet is newly installed, annually thereafter, or if the cabinet is moved to a new location
  • Cabinet Maintenance Certification Tests HEPA filter leak test Inflow and downflow verification Airflow smoke pattern test Electrical safety Vibration, sound and lighting intensity tests (optional comfort tests)
  • Cabinet Maintenance What to Look For in a Certifier Accredited by an independent organization (NSF, AFCA, CETA) Has attended cabinet manufacturer certifier training course Membership in professional organizations Experience with the cabinet type and model References Written estimates before work is begun
  • Operating Procedures Myths, Lies and Gobbledygook "I've got to use a Bunsen burner in my Biosafety Cabinet..." During operation, the flame of a burner is very disruptive to the airflow patterns of the cabinet, and may actually increase the dispersion of aerosols throughout the work area. If the flame of the burner is too large, the excessive heat may melt the adhesive holding the HEPA filter together or literally burn holes in the filter media. An unattended burner may blow out. In a Type A1 or A2 cabinet, the gas may reach explosive concentrations. Use alternate methods, such as electric incinerators, or disposable inoculating loops. Don’t flame bottle mouths; the work area of the biosafety cabinet should be a sterile environment, if used properly.
  • Operating Procedures Myths, Lies and Gobbledygook "I can use a biological safety cabinet as if it were a fume hood..." Do NOT use a biosafety cabinet like a fume hood! The Fume Hood is designed to remove noxious or toxic fumes and aerosols away from the operator. It should be constructed of materials that are inert to a wide variety of chemical agents. The Biosafety Cabinet's primary purpose is to protect the operator, environment, and often the product from biohazardous contaminants. The biosafety cabinet and its HEPA filters are constructed of materials that are inert to the chemicals used in connection with biological research, but may be damaged by some of the more corrosive chemicals commonly used in fume hoods.
  • Operating Procedures Myths, Lies and Gobbledygook "If I work in a biohazard cabinet, I don't have to be as careful with my technique." Wrong. The biosafety cabinet will provide Personnel and Product protection only if used properly. Aseptic technique must be practiced at all times while working in a Biohazard Cabinet.
  • Operating Procedures Myths, Lies and Gobbledygook "If I use the UV light, do I need to decontaminate the work area?" Yes. The UV light is only an adjunct, to minimize contamination of the work area when the cabinet is not in use. UV light has practically no penetrating power, and will not kill microbes protected by dust, dirt, or organic material. The best method to prevent contamination in the cabinet is regular decontamination of the work area surfaces, before and after each work session.
  • Operating Procedures Myths, Lies and Gobbledygook "Can I put a centrifuge in the biosafety cabinet? " You shouldn’t. Large objects placed in the work area will impede the airflow, reducing the efficiency of the cabinet. Electrical appliances like centrifuges, blenders, etc. often have cooling fans that can disrupt the cabinet’s airflow. It’s better to use sealed safety cups in the centrifuge that are loaded and unloaded in the safety cabinet.
  • Operating Procedures Myths, Lies and Gobbledygook "A Type B cabinet will give better protection than a Type A." Not Necessarily. If you’re talking about protection from volatile toxic chemicals, yes; if your talking about protection from biohazardous aerosols, no. Assuming the units being considered are both NSF listed, they were both subjected to the same biological challenge testing. Any claims of superior containment should be documented.
  • Operating Procedures Myths, Lies and Gobbledygook "All biohazard cabinets should operate continuously.” In some applications, such as working with cytotoxic drugs, it is recommended the cabinet operate continuously, to prevent the escape of toxic material. In most applications, operating the cabinet continuously will only shorten the life of the HEPA filters.
  • Operating Procedures Myths, Lies and Gobbledygook "If I leave the biosafety cabinet operating continuously, it will clean the air to Class 5 conditions.” Assuming you have an air-tight room, with no ventilation system, and no activity in it, then a recirculating Type A cabinet might clean the air to Class 5 levels. Unfortunately, as soon as the user entered the room, particle-laden air would re-contaminate the room. All this will really do is shorten the life of the HEPA filters.
  • Operating Procedures Myths, Lies and Gobbledygook "I’ve heard that you should replace HEPA filters annually.” Not necessarily, HEPA filters should be replaced when the pressure differential across them becomes excessive. The Purifier Logic Filter Life gauge will alert the user when the HEPA filters should be replaced. The two biggest factors in filter life are the level of contaminants in the room air, and how many hours the cabinet operates. Arbitrarily replacing HEPA filters on a timetable, without regard to loading may be unnecessarily expensive and wasteful.
  • Labconco Corporation 8811 Prospect Ave. Kansas City, MO 64132 1-800-821-5525 816-333-8811 www.labconco.com
  • www.labconco.com