0
•What is Diabetes
  •How is it treated
  •Side effects and prevention




4/28/2009                        1
•There are 21 million
people in the U.S.
with Diabetes Mellitus
•This represents 6%
of the population
•1 million new cases...
•Although there are
genetic factors, the
number one cause of
diabetes mellitus is
poor diet, leading to
obesity which is w...
A fasting glucose test is good, but
complicated by epinephrine:
             -blocks insulin secretion
             -stimu...
•Poor glucose control
•Glycation of tissues
causing change in cells,
with basement
membrane thickening
and small vessel di...
The changes that happen
to the tissues causes more
than loss of sensation
Changes lead to:
• retinopathy
• nephropathy
• c...
Neuropathy
–Autonomic
    -Dry skin which is easily injured
    because it is thick, rough, non-
    pliable
–Motor
    –A...
Secondary:Pancreatic (β-cell mass loss)
Primary: Type I Diabetes Mellitus
         -autoimmune                            ...
Type I (<40 years of age)                 Type II (>40 years of age)
         -genetically susceptible                  -a...
Most oral diabetes
medications act to either
increase the production
of insulin to match
caloric intake or increase
the ef...
4/28/2009   11
4/28/2009   12
•Never ignore a red mark, a
         bruise or blister
•Never ignore an ingrown
         nail or local trauma




•A ‘litt...
Look for:




            Insect or animal bites




              High Pressure Points




4/28/2009                     ...
Look for hot spots




Good shoes          Not good shoes




4/28/2009                            15
Final Points………
                      •Check feet daily
                      • Wear shoes at all times
                  ...
Thank you!




            Office: 5350 South Stapes Street, Suite 100 (New York Life Building),
                         ...
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New Dm Lecture

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Transcript of "New Dm Lecture"

  1. 1. •What is Diabetes •How is it treated •Side effects and prevention 4/28/2009 1
  2. 2. •There are 21 million people in the U.S. with Diabetes Mellitus •This represents 6% of the population •1 million new cases are diagnosed each year •5 million are undiagnosed 4/28/2009 2
  3. 3. •Although there are genetic factors, the number one cause of diabetes mellitus is poor diet, leading to obesity which is why exercise and diet control is so important in the management of the disease 4/28/2009 3
  4. 4. A fasting glucose test is good, but complicated by epinephrine: -blocks insulin secretion -stimulates glucagon release -activates glycogen breakdown -impairs insulin action via increased hepatic glucose production Also complicated in the face of: -illness -diet -decreased physical exercise 4/28/2009 4
  5. 5. •Poor glucose control •Glycation of tissues causing change in cells, with basement membrane thickening and small vessel disease •Neurologic, immunologic and vascular compromise results 4/28/2009 5
  6. 6. The changes that happen to the tissues causes more than loss of sensation Changes lead to: • retinopathy • nephropathy • coronary arterial disease and stroke 4/28/2009 6
  7. 7. Neuropathy –Autonomic -Dry skin which is easily injured because it is thick, rough, non- pliable –Motor –Atrophy of muscles with contractures of digits –Sensory -Loss of sensation leads to injured skin which is unrecognized -Wound extending to bone means amputation -One amputation usually leads to another 4/28/2009 7
  8. 8. Secondary:Pancreatic (β-cell mass loss) Primary: Type I Diabetes Mellitus -autoimmune -Hormonal (pheochromocytosis, acromegaly, Cushing's, steroids) Type II Diabetes Mellitus -Drug or chemical induced -non-obese -Insulin receptor abnormalities -obese -Genetic syndromes -maturity onset of the young (lipodystrophy, myotonic dystrophy, ataxia/telangiectasias) -Other 4/28/2009 8
  9. 9. Type I (<40 years of age) Type II (>40 years of age) -genetically susceptible -abnormal insulin secretion (HLAD region) -resistance to insulin @ target -environmental event (virus) tissues -both β and α cell mass is intact, -insulinitis (action of T- but α mass is increased lymphocytes) -autoimmunity -insulin levels are normal to high -β-cell attack (islet cell Ab) -rare ketoacidosis, usually lactic acid HHNK (hyperglycemic, -DM (>90% of β-cells) hyperosmolar, non-ketoacidosis) induced coma Ketoacidosis follows decreased insulin and increased glucagon, leading to osmotic diuresis and dehydration 4/28/2009 9
  10. 10. Most oral diabetes medications act to either increase the production of insulin to match caloric intake or increase the effectiveness of the insulin at the target cell via up regulation of receptors 4/28/2009 10
  11. 11. 4/28/2009 11
  12. 12. 4/28/2009 12
  13. 13. •Never ignore a red mark, a bruise or blister •Never ignore an ingrown nail or local trauma •A ‘little thing’ can become a big thing—with unfortunate results! 4/28/2009 13
  14. 14. Look for: Insect or animal bites High Pressure Points 4/28/2009 14
  15. 15. Look for hot spots Good shoes Not good shoes 4/28/2009 15
  16. 16. Final Points……… •Check feet daily • Wear shoes at all times • Shake out shoes before wearing • Wear proper fitting shoes • Don’t use hot water on your feet • Check glucose levels every day • Visit primary care doctor regularly • Visit foot care specialist regularly • Attend diabetic classes • Avoid complications by living right, eating right, exercising and staying under control 4/28/2009 16
  17. 17. Thank you! Office: 5350 South Stapes Street, Suite 100 (New York Life Building), Corpus Christi, TX 78411 Phone: 361 888 8878 Fax: 361 888 8815 4/28/2009 17
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