M. Długosz hybrid calcium carbonate polymer microparticles containing silver nanoparticles as antibacterial agent
by Klaster LifeScience Kraków on Oct 17, 2011
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The problem we try to solve is the rising amount of free silver nanoparticles (nAg) in the commercially available products. nAg are excellent antimicrobial agents and are generally considered safe but ...
The problem we try to solve is the rising amount of free silver nanoparticles (nAg) in the commercially available products. nAg are excellent antimicrobial agents and are generally considered safe but their prolonged impact on human body is not well understood therefore it is important to handle them with caution. Our proposition is a novel hybrid material of nAg embedded inside calcium carbonate/polymer microparticles (-CaCO3). The CaCO3 matrix limits the interactions of nAg with environment and human body and enables sustained release of the antimicrobial compound. The hybrid material can be stored as a dry powder and resuspended in water without risk of loosing its antimicrobial properties. The surface of the material can be flexibly modified by polymer adsoption to satisfy the needs of the product. Synthesis is based on simple, fast and inexpensive coprecipitation of CaCO3 in the presence of nAg, sodium polystyrene sulfonate (PSS) and ultrasound. The microbiological and sustained release tests were conducted to prove antimicrobial activity of the hybrid material. What is more quantitive and qualitative analysis were carried out employing vast number of method. The -CaCO3 was already applied to protect high quality down feathers from microorganisms and therefore improve their viability.
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