WHAT IS CANCER? Cancer is a group of more than 100 diseases. Abnormal cell in a part of the body that grows out ofcontrol. Mutation in DNA.
CANCER OF BLOOD CELLS Cancer of blood cells. • Acute lymphocytic leukemia • Chronic lymphocytic leukemia • Acute myelocytic leukemia • Chronic myelocytic leukemia Starts in the cancer that forms blood Bone marrow makes abnormal white blood cells Early in chronic leukemia the leukemia cells can still do some of the work of normal white blood cells
LEUKEMIA Mutations that can trigger leukemia including, theactivation of oncogenes and the detection of tumorsuppressing genes. This disrupts the regulation of cell death, differential,or division. It an occur spontaneously.
CAUSES No known cause Increase in risk with exposure to radiation, benzene,and smoking • 20% of adult myeloid leukemia cases are linked to smoking.
SYMPTOMS Swollen Lymph nodes that usually don’t hurt Fevers or night sweats Frequent infection Feeling weak or tired Bleeding and bruising easily Weight loss for no reason
DIAGNOSIS Repeated complete blood counts Bone marrow examination Personal and family medical history. Bone marrow aspiration Bone marrow biopsy
TREATMENT Chemotherapy • Blood chemistry tests can detect degrees of liver and kidney damage X-Ray MRI Ultrasound Pharmaceutical medication Multi-drug chemotherapy regimen
INDIVIDUAL CONDUCTING CURRENT RESEARCH Pamela S Becker ,MD, PHD• Dr. Becker is a hematology oncologist who treats people with blood disorders, leukemia, lymphoma, multiple myeloma, and myelodysplastic syndrome.• How she became what she is…• At the age of 16 Becker attended a biochemistry summer program put on by the national Science Foundation. The year she graduated from high school she volunteered at a local hospital and worked in the chemistry lab
CURRENT RESEARCH New biological therapies New anticancer drugs, doses, and treatment schedules Combination of drugs, biological therapy, radiationtherapy, and stem cell transplantation. More genetic research
M O R E C U R R E N T R E S E A RC H ! ! Supportive Care?• Clinical trial are underway to find better ways of reducingsymptoms and side effects of current leukemia treatments in order toimprove patients comfort and quality of life.
SCHOLARSHIP AND COMMUNICATION What do the 4 types of leukemia get there names from?• Each main type of leukemia is named according to the type of cellthat’s affected (a myeloid cell or a lymphoid cell) and whether thedisease begins in mature or immature cells.