Scrub typhus

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Scrub typhus

  1. 1. HISTORY  Most wide spread A/C febrile illness caused by orienta tsutsugamushi  First identified in china in 313 AD  Intacellular gram neg.org.isolated in japan in 1930  Zoonoses in nature exists in nature between mites and rodents
  2. 2. Geographical distribution
  3. 3. Mode of transmission  Mite  Rat,Mice  Mite  Rat,Mice Man  Maintained in nature transovarially in mites  Adult and nymph mites are free living  Larva (chiggar) feed on man introducing bacteria
  4. 4. Adult Larva (chigger)
  5. 5. Clinical features  Incubation period 6to20 days  A/C fever and chills 104-105*c  Head ache, Malaise, Prostration,  Macular rashes -5th day  ESCHAR-punched out ulcer with central necrosis  Lymph adenitis  Hepato splenomegally
  6. 6. Eschar
  7. 7. Complications  ARDS  Myocarditis  A/C Renal failure  DIC
  8. 8. Diagnosis and treatment  4 fold increase in antibody titre  Weil felix positive withOXK STRAIN  Immuno peroxidase test  Immuno flurocent test Responds to tetracycline,doxycycline,azithromyci etc.
  9. 9. PREVENTIVE MEASURES  Avoid areas where there is known typhus outbreak  Avoid over crowded living conditions  Spray for ticks fleas mites  Practice good hygeine  Care farmers working in farms,in bushes,andthose who are close to rodents,domestic animals etc.  NO VACCINE at present

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