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Kidney physiology
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Kidney physiology

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    Kidney physiology Kidney physiology Presentation Transcript

    • Kidney Physiology (pg 4)
    • Macroscopic Structure of the Kidney• Cortex: Outer region
    • Macroscopic Structure of the Kidney• Cortex: Outer region• Medulla: Inner region
    • Macroscopic Structure of the Kidney• Cortex: Outer region• Medulla: Inner region• Renal pelvis: large cavity that collects theurine as it is produced. Continuous with ureter
    • Nephrons• Nephrons are the functional unit of the kidney
    • Nephrons• Nephrons are the functional unit of the kidney• Over 1 million nephrons per kidney
    • Nephron StructureNephrons have two parts:
    • Nephron StructureNephrons have two parts:1. Renal corpusclea. Glomerulus: cluster of capillaries
    • Nephron StructureNephrons have two parts:1. Renal corpusclea. Glomerulus: cluster of capillariesb. Glomerular (Bowman’s) Capsule: cup thatsurrounds the glomerulus and receivesblood filtrate from it
    • 2. Renal tubulea. Proximal convoluted tubule: Highly coiled.Located in cortex
    • 2. Renal tubulea. Proximal convoluted tubule: Highly coiled.Located in cortexb. Loop of Henle: A hairpin loop that dips intothe medulla, makes a U-turn, and ascendsback to the cortex
    • 2. Renal tubulea. Proximal convoluted tubule: Highly coiled.Located in cortexb. Loop of Henle: A hairpin loop that dips intothe medulla, makes a U-turn, and ascendsback to the cortexc. Distal convoluted tubule: Coiled, in cortex
    • Urine Formation• Nephrons form urine in 3 steps1. Filtration: Water and small solutes enter thenephron (blood cells and proteins do notenter). Filtrate is similar to blood plasma.
    • Urine Formation• Nephrons form urine in 3 steps1. Filtration: Water and small solutes enter thenephron (blood cells and proteins do notenter). Filtrate is similar to blood plasma.2. Reabsorption: Useful substances(water, glucose, amino acids, needed ions) aretransported out of the filtrate and back intothe blood
    • Urine Formation• Nephrons form urine in 3 steps1. Filtration: Water and small solutes enter thenephron (blood cells and proteins do not enter).Filtrate is similar to blood plasma.2. Reabsorption: Useful substances(water, glucose, amino acids, needed ions) aretransported out of the filtrate and back into theblood3. Secretion: Harmful substances (H+, excessK+, some drugs and poisons) are removed fromthe blood and put into the filtrate