4 psychiatric research


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4 psychiatric research

  1. 1. COURSE : Medical EnglishTEACHER : Dra. Rosa Gonzáles LlontopGROUP : 4THSTUDENTS : * Gastelo Salazar, Kenyi * Jambo Mendoza, Juan * Mayo Cabanillas, Darcy * Perales Carrasco, Tito * Rojas Ramos, Percy * Vásquez Ochoa, PedroCYCLE : 2012 - I
  2. 2. According to a new study of Wisconsin UniversityYoung primates with Have decreased activityhighly anxious of specific genes withintemperaments the amygdala
  3. 3. The genes involved play a major role in formingthe brain connections needed for learning about fears.
  4. 4. The function of genes that promote learningand plasticity occurs in the amygdala
  5. 5. Anxious individuals tended to have decreased expression of a gene called neurotrophic tyrosine kinase, receptor, type 3 (NTRK3)The risk to develop anxiety and depression may be related to the underactivity of particular genes in the developing amygdala
  6. 6. The study helps Support the need for early intervention in children identified as excessively shy and anxious. Point a way to better treatments to decrease the likelihood of children developing more severe psychiatric problems
  7. 7. Therapy Neuronetics transcranial magneticstimulation (TMS) can relieve symptoms ofdepression and has little or no side effects onthe sleep disorder.
  8. 8. The Major Depressive Disorder affects approximately 14.8million, or about 6.7 percent of American adults in a givenyear, according to the National Institute of Mental Health Its the leading cause of disability in ages 15 to 44
  9. 9. The finding resulted from an analysis of a study of 301 patients at 23 sites comparing the anti-depressive effects of the NeuroneticsTranscranial Magnetic Stimulation Therapy System (TMS)treatment in patients resistant to antidepressant medications
  10. 10. The findings, published in the journal Biological Psychiatry in2007,affirmed TMSs effectiveness in depression Sleep problems are a common side effect of major antidepressants: some drugs sedate patients while others stimulate them and increase insomnia.
  11. 11. Insomnia occurs in 50-90 percent of patients withmajor depressive disorder. Other depressed patientscomplain they sleep too much The good news is that TMS does not contribute to insomnia or oversleeping.
  12. 12. TMS targets the prefrontal cortex of the brain, involved inmood regulation as well as other higher-order functions likeplanning, evaluating and decision-making In this procedure, patients sit in a recliner and receive brief pulses of a MRI strength magnet held against the front of the headThe magnetic energy of TMS causes the brain cells closestto the surface of the brain to increase their activity which inturn influences the activity of the brain as a whole.
  13. 13. DEPRESSION Memory storage In depression, the brain becomes less plastic and adaptable, and therefore less able to Such as perform certain tasks. Researchers at Karolinska Institute have traced less brain plasticity reduced functionality in their support cells, and we believe that learning more about these cells may pave the way for radical new treatments for depression.
  14. 14. It has been possible the cure ofmemory dysfunction in depressed is a substance secreted byrats giving them dose of D-serine astrocytes, which are support cells for brain neurons Their memories were checked by repeatedlyThe rats are placed through the two exposed to different objectstests to confirm that they hadsymptoms that are also characteristicof human depression. Then evaluated their level of apathy, releasing the rats in a container with water and observing if or not trying to get out.
  15. 15. The synaptic activity in the hippocampusof rats depressed is much greater thanthe healthy rats but the level of plasticity of rats with depression is less than the healthy rats However by supplying D-serine to the rat brain plasticity with depression improvement. Is expected that advances in the studies will lead to new treatments for depression