10 oncologic research

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10 oncologic research

  1. 1. HUMAN MEDICAL SCHOOL Group:10
  2. 2. Cancer is now recognized as a geneticdisorder arising from errors in cellreplication, arising from various factors, suchas environmental damage by the action ofchemical agents and radiation or evenlifestyle, leading to uncontrolled cellreproduction. Here we see the latest CancerResearch
  3. 3. The Journal of the American MedicalAssociation. Suggest that taking a daily multivitamin may reduce the risk of cancer of older men.
  4. 4. A randomized trial of 14,000 men after 50years or more for an average of 11 years. They found that those taking a daily multivitamin supplement were 8 percent less likely to be diagnosed with cancer than those taking a placebo.
  5. 5. The building blocks of an emerging science that isenabling cancer researchers to break new ground in theway we treat disease. nanotechnology, researchers in the laboratory seek to reduce side effects and improve the effectiveness of cancer drugs. Scientists giving greater control over the selection of treatments.
  6. 6. Ovarian Cancer Screenings Are Not Effective According to a study published last year in the journal of the American medical society of 78.216 American women between the ages of 55 to 74 years half of them have been selected to while the other half not. continue a control that had a duration of 11 to 13 years
  7. 7. ultrasound exams for elevated Levels of and a substance called The screening consisted blood tests CA-125 Which can be a sign of ovarian cancer There was no advantage the death rate from ovarianResult to screening: cancer was the same in the two groups.
  8. 8. Genes Now They Can not Tell Secrets Doctors Utter Dr. Arul Chinnaiyan stared at a printout of gene sequences from a man with cancer, a subject in one of his studies There, Along with the mans cancer genes, was something unexpected - genes of the virus causes AIDS That ...
  9. 9. In laboratories around the world,using genetic tools Researchers are ever more sophisticatedThat to peer into the DNA of cells are increasingly findingthings They Were not looking for Including Information That Could make a big difference to an anonymous donor.
  10. 10. Studies have long Shown an Increased risk ofbreast cancer in women Whose breasts areconsidered "dense," or less fatty.
  11. 11. New research showing patients with breastcancer That dense breasts Were no more likelyto die than other patients. The women with less dense breasts Were more likely to die of Their Breast Cancers The study included more than 9,000 women
  12. 12. The cancers are fueled by stem cells thatchemotherapy drugs do not kill Strategies can be designed to kill Everything has a weakness, with all modern molecular techniques and modern approaches we have, we can kill specific cells within tumors are responsible for its continued growth
  13. 13. molecular tricks allow scientists to make certain tumor cells brightly When these tagged cells are divided, all daughter cells were stained similarly This allowed the researchers to determine if any old cell into a tumor may continue to fuel growth or only a subset of cells is responsible.
  14. 14. Next, the scientists Treated the mice with a chemotherapy drug Rapidly dividing That Kills tumor cells. When the tumors grew back, do as glioblastomas Generally, the scientists used other chemical tricks to seeThatthe new cells were all descendants of thegreen-glowing cells That Were not killed bythe drug.The next step was to see what would happen if thecancer stem cells Were wiped out
  15. 15. Were wiped out, to test That was possible Because of the way the mice Were genetically constructed Without the stem cells, the tumors never grew as large and the animals lived longer. The scientists Concluded That They Had Destroyed the wellspring of the tumor cells renewThat When other cancer cells stop dividingWithin the mass.
  16. 16. Today, only kill cancer medications Generally Rapidly dividing cells scientists do not yet know enough about cancer stem cells to target them Biotech companies and academics are working on the problem.Overall, scientists are finding That grotesquecaricatures Cancers are of normal body tissues said John E.Dick, senior scientist at Torontos Princess Margaret Cancer Center Whose work in the 1990s provided early evidence for stem cells in leukemia
  17. 17. Just as healthy tissues Contain a mix of cells - - ones That are dividing , ones That have taken on distinct identities, and Stem Cells That Periodically replenish the tissue - so, too, do cancers. And just as usual tissue growth Involves acomplicated dance of chemical messages amongcells, so, too, might the growth of cancers.
  18. 18. That complexity makes the prospect of devising newtherapies seem daunting, Dick saidBut, I added, it opens up a whole new menu of Strategies That scientists can try.

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