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10 comparative diagnosis


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  • 1. MALARIA AND BARTONELLOSIS. MEDICAL ENGLISHVera Bances Paul.Paredes Campos ligiaSegura Ríos Patricia.Rodas Regalado Carlota.Pisfil Colchado Carlos.Pintado Coronel Edwin.
  • 2. BARTONELLO SIS What is it? The human Bartonellosis "Peruvian wart" or "Carrions disease" is an infectious disease caused by a bacterium Bartonella bacilliformis, which parasitizes red blood cells from human blood.
  • 3. MALARIA What is it? infectious, serious and to sometimes fatal, produced by a parasite transmitted by the mosquitos Anopheles
  • 4. of
  • 5. MALARIA BARTONELLOSISCausative parasite: protozoa of Causative parasite: proteobacteriathe genus Plasmodium Bartonella bacilliformis-four species: Plasmodium vivax, P.Ovale, P. Malariae and P.Falciparum (the most deadly)Vector of this disease : female Main vector: female of themosquito of the genus Anopheles. mosquito Lutzomyia verrucarumTRANSMISSION ROUTES TRANSMISSION ROUTES-Direct drive through the bite of a ƒ - By the bite of the mosquito.mosquito. ƒ - Transfusion with infected blood.-Also be transmitted by bloodtransfusions or by infected syringes.
  • 6. COMMON SIGNS AND SYMPTOMS MALARIA BARTONELLOSIS FIRST STAGE Acute phase: (Carrions The classic symptoms disease hemolytic anemia fever jaundice
  • 7. DIFFERENT SIGNS AND SYMPTOMS MALARIA FIRST STAGE shivering convulsions hemoglobinuria arthralgia ( joint pain) vomiting retinal damage
  • 8. DIFFERENT SIGNS AND SYMPTOMS Acute phase: (Carrions BARTONELLOSIS FIRST disease STAGE pallor malaise nonpainful hepatomegaly lymphadeopathy
  • 9. COMMON SIGNS AND SYMPTOMS MALARIA BARTONELLOSIS Chronic phase (or Peruvian wart Severe malaria SECOND STAGE Peruvian Wart) Hepatomegaly Splenomegaly normal spleen enlarged spleen
  • 10. DIFFERENT SIGNS AND SYMPTOMS MALARIA SECOND STAGE severe headache hypoglycemia renal failure cerebral ischemia
  • 11. DIFFERENT SIGNS AND SYMPTOMS BARTONELLOSIS Chronic phase (or Peruvian wart Peruvian Wart) "Peruvian warts" or "Peruvian wart". myalgias SECOND STAGE arthralgias lymphadeopathy
  • 12. What are the possible consequences? Malaria BartonellosisThe consequences are often If the infection is notfatal, if not treated quickly. treated, the mortality rate can be as high as 85%
  • 13. What are the possible consequences? Malaria Bartonellosis Hemolytic anemia. Purple thrombocytopenicThe rupture of a large number Complication hematologicof red blood cells will produce recently reported that may occursignificant anemia. with evolution favorable.
  • 14. What are the possible consequences? Malaria BartonellosisCerebral malaria, that usually Complications have beenends in a box coma. reported neurological
  • 15. What are the possible consequences? Malaria Bartonellosis Acute renal failure Acute hemolysis Associated with feverAccentuated due to hemolysis, manifestedas a decrease in the amount of urine. Parasitized erythrocytes bartonellosis
  • 16. Malaria treatmentChloroquine 500 mg orally 1 time a week Adults: 500 mg every 8 hours for 3-10 days. Quinine Children: 8.2 mg / kg every 8 hours for 3 to 10 days. For travelers going to areas where it isAlternative treatment known to occur Falciparum malaria, there are several options for malaria: mefloquine, atovaquone / proguanil and doxycycline. tetracycline or clindamycin
  • 17. Bartonellosis treatment In general it is recommended to use:•In addition to another antimicrobialagent as a beta lactam.•For the effective treatment of B. CHLORAMPHENICOLbacilliformis and protect against anysecondary bacterial infectionThe rifampin or CIPROFLOXACIN, STREPTOMYCIN,streptomycin is used to TETRACYCLINE ORtreat chronic bartonellosis ERYTHROMYCIN
  • 18. Malaria diagnosis.Examination of samples of peripheral blood.Detection of parasite antigens.Molecular techniques.Serology.
  • 19. Bartonellosis Diagnostics.Reaction Polymerase ChainBlood smears stained with Giemsa.Agar cultures and Cell cultures.Identification of the isolates.Indirect fluorescent antibody testWestern blot