MALARIA AND BARTONELLOSIS. MEDICAL ENGLISHVera Bances Paul.Paredes Campos ligiaSegura Ríos Patricia.Rodas Regalado Carlota.Pisfil Colchado Carlos.Pintado Coronel Edwin.
BARTONELLO SIS What is it? The human Bartonellosis "Peruvian wart" or "Carrions disease" is an infectious disease caused by a bacterium Bartonella bacilliformis, which parasitizes red blood cells from human blood.
MALARIA What is it? infectious, serious and to sometimes fatal, produced by a parasite transmitted by the mosquitos Anopheles
MALARIA BARTONELLOSISCausative parasite: protozoa of Causative parasite: proteobacteriathe genus Plasmodium Bartonella bacilliformis-four species: Plasmodium vivax, P.Ovale, P. Malariae and P.Falciparum (the most deadly)Vector of this disease : female Main vector: female of themosquito of the genus Anopheles. mosquito Lutzomyia verrucarumTRANSMISSION ROUTES TRANSMISSION ROUTES-Direct drive through the bite of a ƒ - By the bite of the mosquito.mosquito. ƒ - Transfusion with infected blood.-Also be transmitted by bloodtransfusions or by infected syringes.
COMMON SIGNS AND SYMPTOMS MALARIA BARTONELLOSIS FIRST STAGE Acute phase: (Carrions The classic symptoms disease hemolytic anemia fever jaundice
DIFFERENT SIGNS AND SYMPTOMS MALARIA FIRST STAGE shivering convulsions hemoglobinuria arthralgia ( joint pain) vomiting retinal damage
DIFFERENT SIGNS AND SYMPTOMS Acute phase: (Carrions BARTONELLOSIS FIRST disease STAGE pallor malaise nonpainful hepatomegaly lymphadeopathy
COMMON SIGNS AND SYMPTOMS MALARIA BARTONELLOSIS Chronic phase (or Peruvian wart Severe malaria SECOND STAGE Peruvian Wart) Hepatomegaly Splenomegaly normal spleen enlarged spleen
DIFFERENT SIGNS AND SYMPTOMS MALARIA SECOND STAGE severe headache hypoglycemia renal failure cerebral ischemia
DIFFERENT SIGNS AND SYMPTOMS BARTONELLOSIS Chronic phase (or Peruvian wart Peruvian Wart) "Peruvian warts" or "Peruvian wart". myalgias SECOND STAGE arthralgias lymphadeopathy
What are the possible consequences? Malaria BartonellosisThe consequences are often If the infection is notfatal, if not treated quickly. treated, the mortality rate can be as high as 85%
What are the possible consequences? Malaria Bartonellosis Hemolytic anemia. Purple thrombocytopenicThe rupture of a large number Complication hematologicof red blood cells will produce recently reported that may occursignificant anemia. with evolution favorable.
What are the possible consequences? Malaria BartonellosisCerebral malaria, that usually Complications have beenends in a box coma. reported neurological
What are the possible consequences? Malaria Bartonellosis Acute renal failure Acute hemolysis Associated with feverAccentuated due to hemolysis, manifestedas a decrease in the amount of urine. Parasitized erythrocytes bartonellosis
Malaria treatmentChloroquine 500 mg orally 1 time a week Adults: 500 mg every 8 hours for 3-10 days. Quinine Children: 8.2 mg / kg every 8 hours for 3 to 10 days. For travelers going to areas where it isAlternative treatment known to occur Falciparum malaria, there are several options for malaria: mefloquine, atovaquone / proguanil and doxycycline. tetracycline or clindamycin
Bartonellosis treatment In general it is recommended to use:•In addition to another antimicrobialagent as a beta lactam.•For the effective treatment of B. CHLORAMPHENICOLbacilliformis and protect against anysecondary bacterial infectionThe rifampin or CIPROFLOXACIN, STREPTOMYCIN,streptomycin is used to TETRACYCLINE ORtreat chronic bartonellosis ERYTHROMYCIN
Malaria diagnosis.Examination of samples of peripheral blood.Detection of parasite antigens.Molecular techniques.Serology.
Bartonellosis Diagnostics.Reaction Polymerase ChainBlood smears stained with Giemsa.Agar cultures and Cell cultures.Identification of the isolates.Indirect fluorescent antibody testWestern blot