WORKING FOR A HEALTHY FUTURECalibration of the DREAM model forthe dermal exposure assessment ofworkers in theGuLFSTUDYJohn...
WORKING FOR A HEALTHY FUTURECalibration of the DREAM model forthe dermal exposure assessment ofworkers in theGuLFSTUDYJohn...
Summary…•    Original studies to validate DREAM•    GuLF DREAM•    Two examples using the adapted model•    Preliminary da...
Original DREAM studies…•    Fully described in initial paper, implemented in     Microsoft Access•    The accuracy was ass...
GuLF DREAM    Body surface    factor                   Emission            Deposition                                  Tra...
GuLF DREAM             5
Boom deployment, near shore…•    Deployed by small vessels•    Oil was present on the water•    Occasionally had to anchor...
Boom retrieval, near shore…•    Retrieved by vessels or boats of all sizes, but on     small boats mainly manual work•    ...
Validation and calibration•    Validate and calibrate revised model against measurement     data•    Have identified sourc...
Biocide spraying…                    9
Heavy fuel oil…                  10
Discussion…•    There are no dermal exposure data for the GuLF     study!•    Updated model provides a promising basis for...
Upcoming SlideShare
Loading in...5
×

GuLF dream calibration/validation

249

Published on

A presentation given at X2012 as part of a session of the GuLF study.

Published in: Health & Medicine, Technology
0 Comments
0 Likes
Statistics
Notes
  • Be the first to comment

  • Be the first to like this

No Downloads
Views
Total Views
249
On Slideshare
0
From Embeds
0
Number of Embeds
1
Actions
Shares
0
Downloads
2
Comments
0
Likes
0
Embeds 0
No embeds

No notes for slide
  • Thanks, acknowledge co-authors and sponsorship
  • Thanks, acknowledge co-authors and sponsorship
  • For skin exposures to the hands, spearman correlation coefficients for individual observations ranged from 0.19 to 0.82. CP removal, OS surrogate skin, MWF flourescence
  • Estimating alkylatedPAHsLarge part of the difference due to PF for gloves and clothing, e.g. for gloves the net PF went from 0.03 to 0.35
  • R2 = 0.8
  • R2 for HFO is 0.1
  • GuLF dream calibration/validation

    1. 1. WORKING FOR A HEALTHY FUTURECalibration of the DREAM model forthe dermal exposure assessment ofworkers in theGuLFSTUDYJohn W Cherrie1, Melanie Gorman Ng1, Anne Sleeuwenhoek1,Mark Stenzel2, Richard Kwok3, Berna van Wendel de Joode4,Patricia Stewart51 Institute of Occupational Medicine, Centre for Human Exposure Science (CHES)2 Exposure Assessment Applications, LLC3 National Institute of Environmental Health Sciences4 Universidad Nacional de Costa Rica5 Stewart Exposure Assessments, LLCINSTITUTE OF OCCUPATIONAL MEDICINE . Edinburgh . UK www.iom-world.org
    2. 2. WORKING FOR A HEALTHY FUTURECalibration of the DREAM model forthe dermal exposure assessment ofworkers in theGuLFSTUDYJohn W Cherrie1, Melanie Gorman Ng1, Anne Sleeuwenhoek1,Mark Stenzel2, Richard Kwok3, Berna van Wendel de Joode4,Patricia Stewart51 Institute of Occupational Medicine, Centre for Human Exposure Science (CHES)2 Exposure Assessment Applications, LLC3 National Institute of Environmental Health Sciences4 Universidad Nacional de Costa Rica5 Stewart Exposure Assessments, LLCINSTITUTE OF OCCUPATIONAL MEDICINE . Edinburgh . UK www.iom-world.org
    3. 3. Summary…• Original studies to validate DREAM• GuLF DREAM• Two examples using the adapted model• Preliminary data to help validate the adapted model 2
    4. 4. Original DREAM studies…• Fully described in initial paper, implemented in Microsoft Access• The accuracy was assessed by comparing DREAM assessments with measured exposure • Hands and other body parts • Variety of measurement methods, removal and interception samplers • Six different situations/agents• Spearman correlation coefficients for individual observations ranged from 0.19 to 0.82 van Wendel de Joode B, Vermeulen R, van Hemmen JJ, et al. Accuracy of a semiquantitative method for Dermal Exposure Assessment (DREAM). Occup 3 Environ Med 2005;62:623–32.
    5. 5. GuLF DREAM Body surface factor Emission Deposition Transfer Clothing 4
    6. 6. GuLF DREAM 5
    7. 7. Boom deployment, near shore…• Deployed by small vessels• Oil was present on the water• Occasionally had to anchor the boom • could result in the oil or oily water contacting hands.• Hands, forearms, and trouser legs probably got wet with water at times 6
    8. 8. Boom retrieval, near shore…• Retrieved by vessels or boats of all sizes, but on small boats mainly manual work• Significant opportunity for contact of hands, arms, legs and torso with oil and oily water• Wore safety glasses, abrasion- resistant work gloves (e.g. (leather), rubber boots, and a high-visibility garment 7
    9. 9. Validation and calibration• Validate and calibrate revised model against measurement data• Have identified sources of dermal exposure measurement data with contextual information that can be used to make DREAM assessments • IOM (heavy fuel oil) Oil and tar • Herrick et al (asphalt) • Soutar et al (biocides) • Hines et al (pesticides) Dispersants • Stewart et al (pesticides) • Van Wendel de Joode et al (Original DREAM data) 8
    10. 10. Biocide spraying… 9
    11. 11. Heavy fuel oil… 10
    12. 12. Discussion…• There are no dermal exposure data for the GuLF study!• Updated model provides a promising basis for exposure reconstruction• Some weaknesses in current model… • Evaporation and wind speed • Contaminated clothing • Water and washing • Sticky liquids!• Validation problematic because of limited data 11
    1. A particular slide catching your eye?

      Clipping is a handy way to collect important slides you want to go back to later.

    ×