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How does It Work?

Grade Level:    12                   Subject:    Anatomy                                     Prepared By:       Sharetha, Victoria, Alexis, Erycha


Overview & Purpose                                                                           Education Standards Addressed
Passive Transport, Active Transport, Cell Metabolism, Protein synthesis, Growth
                                                                                             This covers “How does it work?” artifact.



                                            Teacher Guide                                  Student Guide

Passive Transport              ·     Diffusion- Often molecules simply       Osmosis, passive- Diffusion of water              Materials:
                               spread or “diffuse” through the               through a selectively permeable membrane          Body
                               membranes. The term “diffusion” refers to     in the presence of at least one impairment
                               a natural phenomenon caused by the            solute.
                                                                                                                               Cells
                               tendency of small particles to spread out     ·     Facilitated diffusion, passive- Diffusion   Anatomy book
                               evenly within any given space. All            of particles through a membrane by means          DNA
                               molecules in a solution bounce around in      of carrier molecules; also called “carrier-       RNA
                               short, chaotic paths. As they collide with    mediated passive transport”.                      Sugar
                               one another, they tend to spread out, or
                               diffuse.
                               ·     Simple diffusion, passive- Movement
                               of particles through the phospholipid
                               bilayer or through channels from an area of
                               high concentration to an area of low
                               concentration that is down the
                               concentration gradient.
                               ·     Dialysis, passive- Diffusion of small
                               solute particles. But not larger solute
                               particles, through a selectively permeable
                               membrane; results In separation of large
                               and small solutes.
                               ·
Active Transport    Active Transport- the movement of solute       Pinocytosis, active- Movement of fluid and
                    particles from an area of low concentration    dissolved molecules into a cell by trapping
                    to an area of high concentration (up the       them in a section of plasma membrane that
                    concentration gradient) by means of carrier    pinches off to form an intracellular vesicle;
                    molecule                                       type of “endocytosis”
                    ·      Phagocytosis, active- Movement of       Exocytosis, active- Movement of proteins or
                    cells or other large particles into cell by    other cell products out of cell by fusing a
                    trapping it in a section of plasma             secretory vesicle with the plasma
                    membrane that pinches off to form an           membrane.
                    intracellular vesicle; type of “endocytosis”


Cell Metabolism     What is a Cell Metabolism?                     The Role of Enzymes in Cell Metabolism          Other Resources
                    It’s the set of chemical reactions in a cell   -Enzymes are chemical catalysts, reducing
                                                                                                                   How Is It Made? Lesson
                                                                   activation energy needed for reaction           Coach Gatlin
                    Two different types of Cell Metabolism                                                         Anatomy and
                                                                   -Chemical structure of enzymes                  Physiology Book
                             1. Catabolism- breaks large
                             molecules into smaller ones;          a) proteins of a complex shape
                             usually releases energy
                             2. Anabolism- builds large            b) the active site is where the enzyme
                             molecules from smaller ones;          molecule fits the substance molecules
                             usually consuming energy



Protein Synthesis   Transcription—synthesis of a mRNA              Translation—process in which mRNA is used
                    molecule                                       by ribosomes in the synthesis of a protein
                        1. mRNA forms along a segment of                1. After leaving the nucleus and being
                             one strand of DNA                              edited, mRNA associates with a
                        2. Noncoding introns are removed                    ribosome in the cytoplasm
                             and remaining exons are spliced            2. tRNA molecules bring specific
                             together to form the final, editing            amino acids to the mRNA at the
                             version of the mRNA copy of the                ribosome; the type of amino acid is
                             DNA segment                                    determined by the fit of a specific
                                                                            tRNA’s anticodon with mRNA’s
                                                                            codon
                                                                        3. As amino acids are brought into
                                                                            place, peptide bonds join them—
                                                                            eventually producing an entire
                                                                            polypeptide chain
Growth   Cell growth—a newly formed cell produces      Cell Reproduction—cells reproduce by         Additional Notes
         a variety of molecules and other structures   splitting themselves into two smaller        WE LOVE ANATOMY!
         necessary for growth using the information    daughter cells
         contained in the genes of DNA molecules;           1. Mitotic cell division—the process
         this stage is known as interphase                       of organizing and distributing
              1. Production of cytoplasm—more                    nuclear DNA during cell division
                   cell material is made, including              has four distinct phases
                   growth and/or replication of                       a. Prophase—“before-
                   organelles and plasma membrane;                        phase”
                   a largely anabolic process.                        b. Metaphase—“position-
              2. DNA replication                                          changing phase”
              3. Growth phase of the cell life cycle                  c. Anaphase—“apart phase
                   can be subdivided into the first                   d. Telophase—“end phase”
                   growth phase (G1), the [DNA]             2. Meiosis –nuclear division in which
                   synthesis phase (S), the second               the number of chromosomes is
                   growth phase (G2)                             reduced to half their original
                                                                 number through separation of
                                                                 homologous pairs; produces
                                                                 gametes

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How does it work?

  • 1. How does It Work? Grade Level: 12 Subject: Anatomy Prepared By: Sharetha, Victoria, Alexis, Erycha Overview & Purpose Education Standards Addressed Passive Transport, Active Transport, Cell Metabolism, Protein synthesis, Growth This covers “How does it work?” artifact. Teacher Guide Student Guide Passive Transport · Diffusion- Often molecules simply Osmosis, passive- Diffusion of water Materials: spread or “diffuse” through the through a selectively permeable membrane Body membranes. The term “diffusion” refers to in the presence of at least one impairment a natural phenomenon caused by the solute. Cells tendency of small particles to spread out · Facilitated diffusion, passive- Diffusion Anatomy book evenly within any given space. All of particles through a membrane by means DNA molecules in a solution bounce around in of carrier molecules; also called “carrier- RNA short, chaotic paths. As they collide with mediated passive transport”. Sugar one another, they tend to spread out, or diffuse. · Simple diffusion, passive- Movement of particles through the phospholipid bilayer or through channels from an area of high concentration to an area of low concentration that is down the concentration gradient. · Dialysis, passive- Diffusion of small solute particles. But not larger solute particles, through a selectively permeable membrane; results In separation of large and small solutes. ·
  • 2. Active Transport Active Transport- the movement of solute Pinocytosis, active- Movement of fluid and particles from an area of low concentration dissolved molecules into a cell by trapping to an area of high concentration (up the them in a section of plasma membrane that concentration gradient) by means of carrier pinches off to form an intracellular vesicle; molecule type of “endocytosis” · Phagocytosis, active- Movement of Exocytosis, active- Movement of proteins or cells or other large particles into cell by other cell products out of cell by fusing a trapping it in a section of plasma secretory vesicle with the plasma membrane that pinches off to form an membrane. intracellular vesicle; type of “endocytosis” Cell Metabolism What is a Cell Metabolism? The Role of Enzymes in Cell Metabolism Other Resources It’s the set of chemical reactions in a cell -Enzymes are chemical catalysts, reducing How Is It Made? Lesson activation energy needed for reaction Coach Gatlin Two different types of Cell Metabolism Anatomy and -Chemical structure of enzymes Physiology Book 1. Catabolism- breaks large molecules into smaller ones; a) proteins of a complex shape usually releases energy 2. Anabolism- builds large b) the active site is where the enzyme molecules from smaller ones; molecule fits the substance molecules usually consuming energy Protein Synthesis Transcription—synthesis of a mRNA Translation—process in which mRNA is used molecule by ribosomes in the synthesis of a protein 1. mRNA forms along a segment of 1. After leaving the nucleus and being one strand of DNA edited, mRNA associates with a 2. Noncoding introns are removed ribosome in the cytoplasm and remaining exons are spliced 2. tRNA molecules bring specific together to form the final, editing amino acids to the mRNA at the version of the mRNA copy of the ribosome; the type of amino acid is DNA segment determined by the fit of a specific tRNA’s anticodon with mRNA’s codon 3. As amino acids are brought into place, peptide bonds join them— eventually producing an entire polypeptide chain
  • 3. Growth Cell growth—a newly formed cell produces Cell Reproduction—cells reproduce by Additional Notes a variety of molecules and other structures splitting themselves into two smaller WE LOVE ANATOMY! necessary for growth using the information daughter cells contained in the genes of DNA molecules; 1. Mitotic cell division—the process this stage is known as interphase of organizing and distributing 1. Production of cytoplasm—more nuclear DNA during cell division cell material is made, including has four distinct phases growth and/or replication of a. Prophase—“before- organelles and plasma membrane; phase” a largely anabolic process. b. Metaphase—“position- 2. DNA replication changing phase” 3. Growth phase of the cell life cycle c. Anaphase—“apart phase can be subdivided into the first d. Telophase—“end phase” growth phase (G1), the [DNA] 2. Meiosis –nuclear division in which synthesis phase (S), the second the number of chromosomes is growth phase (G2) reduced to half their original number through separation of homologous pairs; produces gametes