Health Sciences Library
Current Awareness Bulletin
Date: February 2008
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NEW BOOKS IN THE LIBRARY
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WEBSITES [Ctrl + click for links]
From Biomed Central
29 January 2008
BioMed Central bolsters radiology image collection
BioMed Central has partnered with the American Roentgen Ray Society to add more journals and
images to GoldMiner(tm), the ARRS radiology search engine.
BioMed Central, the open access publisher of peer-reviewed biomedical research has contributed
over 170 journals, adding over 4,200 images to the GoldMiner(tm) collection. The collection now
numbers over 170,000 images and over 225 journals.
"GoldMiner(tm) speeds your search for radiology images by quickly matching search criteria with
peer-reviewed content available on the Web," said Charles E. Kahn, Jr., MD, a creator of
GoldMiner(tm). "By limiting results to images from respected, peer-reviewed journals, you won't
spend a lot of time sifting through thousands of unrelated images or images from unknown
sources. You can save more time by filtering by imaging modality, patient age and gender," said
"BioMed Central is very happy to be partnering with the ARRS to expand their radiology image
search tool with the indexing of thousands of openly licensed images from our journals," said
Matthew Cockerill, publisher of BioMed Central. "We are always keen to encourage creative use
of the open access articles which we publish and GoldMiner(tm) is a great example of this," he
22/1/08 National PACS steering group disbanded
A shake-up in national governance arrangements for PACS across England has been signalled
by Connecting for Health (CfH).
From Health Management Specialist Library
Report into the effects of CT scanning asymptomatic people
The Committee on Medical Effects of Radiation in the Environment [COMARE] has published its
12th Report: The impact of personally initiated X-ray computed tomography scanning for the
health assessment of asymptomatic individuals including recommendations into the regulation of
such tests and consideration of whether or not they are effective in a public health context.
COMARE press release
From Aunt Minnie
9/1/08 Multislice CT detects coronary disease in men and women
NEW YORK (Reuters Health) - Multislice computed tomography (MSCT) coronary angiography
appears highly effective in diagnosing obstructive coronary artery disease in both men and
women, Dutch researchers report in the January issue of Heart. To investigate, Dr. Jereon Bax, of
Leiden University Medical Center, and colleagues studied 50 men and 50 women with known and
suspected coronary artery disease who underwent 64-slice MSCT.
21/1/08 Trauma radiologists overhaul abdominal CT contrast protocols
Radiologists routinely administer both an oral barium suspension and IV contrast for evaluating
suspected appendicitis, diverticulitis, and small-bowel obstruction (SBO). Would studies
work as well without oral contrast? And what about oral iodine? Can it replace barium in
abdominal applications other than virtual colonoscopy? Two research groups recently
explored these issues.
21/1/08 Ultrasound quality strongly affects ovarian cancer management
NEW YORK (Reuters Health) - Improving the quality of pre-operative ultrasound can reduce the
number of unnecessary staging procedures performed to confirm ovarian cancer and can also
shorten the hospital stay, according to a report in the January 21st online issue of The Lancet
23/1/08 Groups advocate less radiation for kids
Thirteen radiology-related organizations are urging healthcare practitioners to significantly reduce
the amount of radiation administered to children during imaging scans.
25/1/08 Cochrane Review studies mammo discomfort
In a review of studies conducted to evaluate ways to reduce mammography exam discomfort,
women's imaging vendor Hologic's MammoPad breast cushions were found to reduce pain,
according to the Cochrane Collaboration of Oxford, U.K.
29/1/08 DMIST: Women under 50 with dense breasts benefit from FFDM
Full-field digital mammography (FFDM) performs significantly better than film-screen in one
particular subgroup of women, according to researchers of the Digital Mammographic Imaging
Screening Trial (DMIST). They examined the DMIST data for 10 subgroups of women, and found
that women younger than 50 with dense breasts benefited the most from FFDM.
31/1/08 False positives a concern with FDG-PET/CT for head, neck tumors
FDG-PET/CT is worthwhile for assessing patients with occult head and neck primary tumors, but
false positives remain a shortcoming of the hybrid technology, according to a British study. The
results show that FDG-PET/CT cannot replace examination under anesthesia and biopsies for
assessing occult head and neck primary tumors.
4/2/08 Dark-field x-ray measures scatter radiation for better image quality
A new technique for producing images could offer a way to create higher-quality images using
conventional digital radiography equipment, according to Swiss researchers. The technique,
called dark-field x-ray, is based on radiation scattered from a target rather than the traditional
method of using radiation absorbed by the target. The researchers discussed their
implementation of dark-field imaging in a paper published in Nature Materials.
5/2/08 Ultrasound shows promise as a screening tool for wrist pain
More than 2.2 million people in the U.S. turn up at their doctor's office with complaints of wrist
pain, but ordering up costly MRI and MR arthrography exams -- or radiation-laden CT
arthrography -- is not always feasible. Orthopedic specialists from Tucson's University of Arizona
have proposed ultrasound-based exams as a screening tool for wrist ligaments.
12/2/08 The use of computer-aided detection (CAD) software for digital radiography (DR) images
is a relatively new application, but the combination could prove useful if DR is to develop a role in
One possible fly in the ointment, however, is the impact of various DR postprocessing techniques
on CAD functionality. DR data can be manipulated, massaged, and processed in various ways,
any one of which could affect CAD's ability to detect suspicious lung nodules.
Chinese researchers address this issue in an article we're featuring this week in our Digital X-Ray
Community. The investigators used a commercially available CAD application to analyze DR
images processed with three different types of image postprocessing techniques.
They found that CAD's performance varied widely based on the type of image processing used,
with statistically significant variations in nodule detection and false-positive rates. Learn more by
clicking here, or visit the community at xray.auntminnie.com.
13/2/08 Study finds that CAD does improve mammography's sensitivity
A new study published this week found that computer-aided detection improves the sensitivity of
mammography screening with only a small boost in the patient recall rate. The research offers a
rebuttal to last year's New England Journal of Medicine study that found that CAD actually
reduced the accuracy of breast screening centers that used it.
Click here to read the rest of the article.
14/2/08 A new study published this week has reignited the debate over the use of computer-
aided detection (CAD) software for mammography screening. The new research finds that CAD
has a beneficial role in breast screening, contradicting the results of last year's controversial study
in the New England Journal of Medicine.
In the new study, U.S. researchers analyzed their experience with CAD in more than 230,000
patients over four years, according to an article in our Women's Imaging Digital Community by
staff writer Kate Madden Yee. The methodology specifically addressed a number of the perceived
shortcomings in the earlier NEJM study that CAD proponents believe reduced the accuracy for
sites using CAD.
The new study found that sites using CAD turned in results that were superior compared to those
of a single reader, and comparable to double reading by two radiologists. What's more, CAD's
recall rate didn't exceed that of double reading.
The question is, what impact will the study have on recent efforts by insurance payors to restrict
CAD reimbursement? So far, CAD advocates have successfully beaten back most of the
proposed cuts -- this week's study should give them another weapon in their arsenal. Get the rest
of the details by clicking here.
21/2/08 Medical imaging has become a crucial tool in managing acute stroke patients.
Technologies like CT and MRI have developed indispensable roles in determining the course of
treatment during the "golden hour," when at-risk brain tissue can be saved by the accurate
administration of therapy.
But imaging's role in stroke diagnosis and treatment is still evolving, and that's the subject of a
new series on stroke imaging we're featuring this week in our CT Digital Community by staff writer
In part I of the series, we examine the role of imaging in identifying brain tissue that can be
salvaged through early and effective treatment. Part of the problem is that, despite recent
advancements, medical imaging is still limited to simplistic representations of brain physiology.
Even some of the terms imaging specialists use to describe at-risk brain tissue -- such as the
term "penumbra" -- aren't completely accurate. Learn more about the current state of the art in
stroke imaging by clicking here. We'll be running part II of this series in our next CT Insider
newsletter, so make sure you're signed up to get it. To register as a CT Insider (or for any of our
other Insider newsletters), just click on the "Newsletters" link at the top of any AuntMinnie Web
page when you're logged in. The link will take you to a page where you can manage your
AuntMinnie newsletters just by checking the boxes beside each one.
JOURNAL ARTICLES AVAILABLE FROM THE HEALTH SCIENCES LIBRARY
AMERICAN JOURNAL OF ROENTGENOLOGY
2007 ; VOL 190 ; PART 2
Article Title: The Image Gently Campaign : Working Together to Change Practice
Author(s): Goske , M . J . ; Applegate , K . E . ; Boylan , J .
Article Title: CMS 2008 Rulemaking Focuses on Curbing Self - Referred Imaging
Author(s): Greeson , T . W . ; Zimmerman , H . M .
Article Title: Dual - Phase CT of Autoimmune Pancreatitis : A Multireader Study
Takahashi , N . ; Fletcher , J . G . ; Fidler , J . L . ; Hough , D . M . ;
Kawashima , A ; Chari , S . T .
MR Enterography of Small - Bowel Lymphoma : Potential for Suggestion of
Histologic Subtype and the Presence of Underlying Celiac Disease
Lohan , D . G . ; Alhajeri , A . N . ; Cronin , C . G . ; Roche , C . J . ; Murphy ,
J . M
Article Title: Gas Bubble Motion Artifact in MDCT
Liu , F . ; Cuevas , C . ; Moss , A . A . ; Kolokythas , O . ; Dubinsky , T . J . ;
Kinahan , P . E .
Transient Homogeneously Enhancing Hepatic Masses : Can Size Predict
Author(s): Hughes - Cassidy , F ; Wong , J . ; Aguirre , D .
Automated Threshold - Based 3D Segmentation Versus Short - Axis
Planimetry for Assessment of Global Left Ventricular Function with Dual -
Author(s): Juergens , K . U . ; Seifarth , H . ; Range , R .
Radiation Dose , Image Quality , Stenosis Measurement , and CT
Densitometry Using ECG - Triggered Coronary 64 - MDCT Angiography : A
Author(s): Horiguchi , J . ; Kiguchi , M . ; Fujioka , C .
Repeatability Limits for Measurement of Coronary Artery Calcified Plaque
with Cardiac CT in the Multi - Ethnic Study of Atherosclerosis
Author(s): Chung , H . ; McClelland , R . L . ; Katz , R . ; Carr , J . J . ; Budoff , M . J
Routine Pelvic and Lower Extremity CT Venography in Patients Undergoing
CT Pulmonary Angiography
Author(s): Hunsaker , A . R . ; Zou , K . H . ; Poh , A . C .
Dynamic Oxygen - Enhanced MRI Versus Quantitative CT : Pulmonary
Functional Loss Assessment and Clinical Stage Classification of Smoking -
Author(s): Ohno , Y . ; Koyama , H . ; Nogami , M .
Prediction of Perceptible Artifacts in JPEG 2000 - Compressed Chest CT
Images Using Mathematical and Perceptual Quality Metrics
Author(s): Kim , B . ; Lee , K H . ; Kim , K . J .
Article Title: Radiation Dose Reduction in Chest CT : A Review
Author(s): Kubo , T . ; Lin , P J . P . ; Stiller , W .
Effect of Patient Size on Radiation Dose for Abdominal MDCT with
Automatic Tube Current Modulation : Phantom Study
Author(s): Schindera , S . T . ; Nelson , R . C . ; Toth , T . L .
Two - Step Postmortem Angiography with a Modified Heart - Lung Machine :
Author(s): Grabherr , S . ; Gygax , E . ; Sollberger , B .
Article Title: MDCT Analysis of Projectile Injury in Forensic Investigation
Author(s): Harcke , H . T . ; Levy , A . D . ; Getz , J . M . ; Robinson , S . R .
Accuracy of Retrograde Ileostomy Radiographic Examination for Detecting
Small - Bowel Abnormalities
Kessler , J . M . ; Levine , M . S . ; Rubesin , S . E . ; Rombeau , J . L . ;
Laufer , I
Noncathartic CT Colonography with Stool Tagging : Performance With and
Without Electronic Stool Subtraction
Author(s): Johnson , C . D . ; Manduca , A . ; Fletcher , J . G .
Imaging Findings in Roux - en - O and Other Misconstructions : Rare but
Serious Complications of Roux - en - Y Gastric Bypass Surgery
Author(s): Mitchell , M . T . ; Gasparaitis , A . E . ; Alverdy , J . C .
Critical Analysis of the Performance of Double - Contrast Barium Enema for
Detecting Colorectal Polyps > or = 6 mm in the Era of CT Colonography
Author(s): Sosna , J . ; Sella , T . ; Sy , O .
Asymptomatic Pneumatosis at CT Colonography : A Benign Self - Limited
Imaging Finding Distinct from Perforation
Author(s): Pickhardt , P . J . ; Kim , D . H . ; Taylor , A . J .
MR Defecography : Prospective Comparison of Two Rectal Enema
Author(s): Solopova , A . E . ; Hetzer , F . H . ; Marincek , B . ; Weishaupt , D .
Nonobstructing Renal Stones on Unenhanced CT : A Real Cause for Renal
Author(s): Furlan , A . ; Federle , M . P . ; Yealy , D . M . ; Averch , T . D . ; Pealer , K
3 - T Contrast - Enhanced MR Angiography in Evaluation of Suspected
Intracranial Aneurysm : Comparison with MDCT Angiography
Author(s): Nael , K . ; Villablanca , J . P . ; Mossaz , L .
Original Research . Preoperative Evaluation of Bile Duct Cancer : MRI
Combined with MR Cholangiopancreatography Versus MDCT with Direct
Author(s): Park , H . S . ; Lee , J . M . ; Choi , J . Y .
Pictorial Essay . CT of Serous Cystadenoma of the Pancreas and Mimicking
Author(s): Kim , H . J . ; Lee , D . H . ;Ko , Y . T . ;Lim , J . W . ;Kim , H . C . ;Kim , K . W
Original Research . Percutaneous Imaging - Guided Solid Organ Core
Needle Biopsy : Coaxial Versus Noncoaxial Method
Author(s): Hatfield , M . K . ; Beres , R . A . ; Sane , S . S . ; Zaleski , G . X .
Original Research . Radiofrequency Ablation of Liver Adjacent to Body of
Gallbladder : Histopathologic Changes of Gallbladder Wall in a Pig Model .
Author(s): Lee , J . W . ; Rhim , H . ; Jeon , Y . H .
Technical Innovation Adjustment of Laparoscopic Banding Device with the
Aid of an Angiographic Compression Device
Author(s): Tan , C . K . F . ; Walker , G . D .
Technical Innovation Cutting Balloon Treatment for Recurrent Benign
Bronchial Strictures .
Author(s): Shin , J . H . ; Song , H . Y . ; Kim , J . H .
Technical Innovation PET of Hypoxia and Perfusion with ^ 6 ^ 2Cu - ATSM
and ^ 6 ^ 2Cu - PTSM Using a ^ 6 ^ 2Zn / ^ 6 ^ 2Cu Generator .
Author(s): Wong , T . Z . ; Lacy , J . L . ; Petry , N . A .
Original Research . In Vivo Proton Spectroscopy of Giant Cell Tumor of the
Author(s): Sah , P . L . ; Sharma , R . ; Kandpal , H .
Pictorial Essay . Simple Changes to 1 . 5 - T MRI Abdomen and Pelvis
Protocols to Optimize Results at 3 T
Author(s): Cornfeld , D . ; Weinreb , J .
Clinical Observations . MRI Features of Posterior Capitellar Impaction
Author(s): Rosenberg , Z . S . ;Blutreich , S . I . ;Schweitzer , M . E . ;Zember , J .S et al
Original Research . Popliteomeniscal Fascicles : Anatomic Considerations
Using MR Arthrography in Cadavers
Author(s): Peduto , A . J . ; Nguyen , A . ; Trudell , D . J . ; Resnick , D . L .
Article Title: Review . The Posterolateral Corner of the Knee
Author(s): Vinson , E . N . ; Major , N . M . ; Helms , C . A .
Original Research . Diagnostic Accuracy and Reading Time to Detect
Intracranial Aneursyms on MR Angiography Using a Computer - Aided
Diagnosis System .
Author(s): Kakeda , S . ; Korogi , Y . ; Arimura , H .
Original Research . Suppression of Myocardial ^ 1 ^ 8F - FDG Uptake by
Preparing Patients with a High - Fat , Low - Carbohydrate Diet
Author(s): Williams , G . ; Kolodny , ; G . M .
Original Research . Prospective Evaluation of Image Quality with Use of a
Patient Image Gallery for Dose Reduction in Pediatric 16 - MDCT
Author(s): Honnef , D . ; Wildberger , J . E . ; Haras , G .
Original Research . Role of Sonography in the Detection of Contralateral
Metachronous Breast Cancer in an Asian Population
Author(s): Kim , M . J . ; Kim , E . K . ; Kwak , J . Y .
Original Research . Diffusion - Weighted Single - Shot Echo - Planar Imaging
with Parallel Technique in Assessment of Endometrial Cancer .
Author(s): Shen , S . H . ; Chiou , Y . Y . ; Wang , J . H .
Original Research . 3 - T MRI in the Preoperative Evaluation of Depth of
Myometrial Infiltration in Endometrial Cancer .
Author(s): Torricelli , P . ; Ferraresi , S . ; Fiocchi , F .
Original Research . Correlation of Whole - Breast Vascularity with Ipsilateral
Breast Cancers Using Contrast - Enhanced MDCT
Author(s): Kang , D . K . ; Kim , E . J . ; Kim , H . S . ; Sun , J . S . ; Jung , Y . S .
Original Research . Proton MR Spectroscopy in Normal Breasts Between
Pre - and Postmenopausal Women : A Preliminary Study
Author(s): Wang , J . ; Torng , P . L . ; Liu , T . P . ; Chen , K . L . ; Shih , T . T . F
Original Research . Lesion and Patient Characteristics Associated with
Malignancy After a Probably Benign Finding on Community Practice
Author(s): Lehman , C . D . ; Rutter , C . M . ; Eby , P . R . ; White , E . et al
Original Research . Screening - Detected and Symptomatic Ductal
Carcinoma in Situ : Differences in the Sonographic and Pathologic Features .
Author(s): Shin , H . J . ; Kim , H . H . ; Kim , S . M . ; Kwon , G . Y . ; Gong , G . et al
Article Title: Original Research . Physician Workload in Mammography
Author(s): Smith - Bindman , R ; Miglioretti , D . L . ; Rosenberg , R .
BRITISH JOURNAL OF NURSING
VOL 15 NUMB 15 2006 Aug 10-Sep 13
Ward nurses' knowledge of computed tomography scanning
Majeed-M, Nayeemuddin-M, Christie-M.
Walsgrave Hospital University Hospitals of Coventry and Warwickshire NHS Trust
Patients benefit from and are reassured by advance information on procedures that they are to
undergo. Ward nurses should have adequate knowledge of radiological investigations to
ensure proper patient preparation and good interdepartmental communication to avoid delays
and cancellations. This study was conducted to assess the ward nurses' knowledge of the
process of computed tomography (CT) scanning. One hundred and twenty qualified nurses
were asked to complete a questionnaire regarding CT scanning. The findings revealed a
suboptimal level of awareness about the process. This is probably due to lack of formal teaching
for nurses on the wards in regards the different radiological procedures and patient preparation.
There is a strong case for better educational talks on rapidly changing radiological
techniques for ward staff to ensure high-quality patient care.
NEW ENGLAND JOURNAL OF MEDICINE
21 Feb 2008
Computed Tomography and Radiation Exposure
Incidental Findings on Brain MRI
Visualizing Out-of-Body Experience in the Brain
JOURNAL ARTICLES AVAILABLE TO YOU IN FULL TEXT – [Ctrl + click to open link]
Athens password required – contact Library if you do not have one
BMC MEDICAL IMAGING
2008, 8:5 (29 February 2008)
Abdominal ultrasonography in HIV/AIDS patients in Southwestern Nigeria
Obajimi MO, Atalabi MO, Ogbole GI, Adeniji-Sofoluwe AT, Agunloye AM, Adekanmi AJ et al
[Abstract] [Provisional PDF]
2008, 8:4 (29 February 2008)
Post traumatic brain perfusion SPECT analysis using reconstructed ROI maps of
radioactive microsphere derived cerebral blood flow and statistical parametric mapping
McGoron AJ, Capille M, Georgiou MF, Sanchez P, Solano J, Gonzalez-Brito M, Kuluz JW
[Abstract] [Provisional PDF]
Web link to this journal
118(3):501-505, March 2008.
3 Tesla Delayed Contrast Magnetic Resonance Imaging Evaluation of Meniere's Disease
Carfrae, Matthew J. ; Holtzman, Adrian ; Eames, Fred ; Parnes, Steven M. ; Lupinetti, Allison
Objective: To determine whether 3 Tesla (T) magnetic resonance imaging (MRI) with delayed
contrast imaging has sufficient anatomic resolution to image the intracochlear fluid spaces (i.e.,
the scala tympani, scala media, and scala vestibuli) of the inner ear and identify endolymphatic
hydrops in vivo.
Study Design: Four normal subjects underwent 3T MRI scanning after the administration of
gadodiamide intravenous (IV) contrast. MRI region of interest signal intensity was used to
determine the diffusion of gadodiamide into the perilymphatic fluid spaces over time. Seven
subjects with unilateral Meniere's disease underwent 3T MRI 4 hours after administration of
gadodiamide IV contrast agent.
Results: All four normal subjects demonstrated perilymphatic enhancement by 4 hours
postinjection. Loss of definition of the membranous cochlea was noted in five of the seven
subjects with Meniere's disease. Precise definition of the scala media could not be achieved with
this imaging protocol.
Conclusion: Delayed contrast imaging of the inner ear with 3T MRI revealed in vivo changes of
the membranous labyrinth consistent with unilateral Meniere's disease.
Web link to this journal
70(7):512-520, February 12, 2008
MRI patterns of atrophy associated with progression to AD in amnestic mild cognitive
Whitwell, J L.; Shiung, M M.; Przybelski, S A.; Weigand, S D.; Knopman, D S.; Boeve, B F. et al
Objective: To compare the patterns of gray matter loss in subjects with amnestic mild cognitive
impairment (aMCI) who progress to Alzheimer disease (AD) within a fixed clinical follow-up time
vs those who remain stable.
Methods: Twenty-one subjects with aMCI were identified from the Mayo Clinic Alzheimer's
research program who remained clinically stable for their entire observed clinical course (aMCI-
S), where the minimum required follow-up time from MRI to last follow-up assessment was 3
years. These subjects were age- and gender-matched to 42 aMCI subjects who progressed to AD
within 18 months of the MRI (aMCI-P). Each subject was then age- and gender-matched to a
control subject. Voxel-based morphometry (VBM) was used to assess patterns of gray matter
atrophy in the aMCI-P and aMCI-S groups compared to the control group, and compared to each
Results: The aMCI-P group showed bilateral loss affecting the medial and inferior temporal lobe,
temporoparietal association neocortex, and frontal lobes, compared to controls. The aMCI-S
group showed no regions of gray matter loss when compared to controls. When the aMCI-P and
aMCI-S groups were compared directly, the aMCI-P group showed greater loss in the medial and
inferior temporal lobes, the temporoparietal neocortex, posterior cingulate, precuneus, anterior
cingulate, and frontal lobes than the aMCI-S group.
Conclusions: The regions of loss observed in subjects with amnestic mild cognitive impairment
(aMCI) who progressed to Alzheimer disease (AD) within 18 months of the MRI are typical of
subjects with AD. The lack of gray matter loss in subjects with aMCI who remained clinically
stable for their entire observed clinical course is consistent with the notion that patterns of atrophy
on MRI at baseline map well onto the subsequent clinical course.
Web link for this journal
33(4):E109-E115, February 15, 2008
Surgical Results in Hidden Lumbar Spinal Stenosis Detected by Axial Loaded Computed
Tomography and Magnetic Resonance Imaging: An Outcome Study
Willen, Jan ; Wessberg, Per J. ; Danielsson, Barbro
Study Design. An outcome study of patients with neurogenic claudication and/or sciatica with
hidden stenosis, detected only by axial loading of the lumbar spine (ACE) but not at the traditional
unloaded examination (psoas relaxed position) during computed tomography (CT) myelography
or magnetic resonance imaging (MRI), followed up after surgery.
Objective. To estimate the clinical effect of decompression with or without fusion in patients with
hidden stenosis in the lumbar spine.
Summary of Background Data. A number of patients with neurogenic claudicatio with or without
sciatica do not have corresponding imaging abnormalities. Axial loaded CT and MRI have
disclosed hidden stenosis in certain cases. The surgical effect in patients with hidden stenosis
has never been described.
Methods and Materials. Axial loading of the lumbar spine during CT and MRI was performed in
250 patients with neurogenic claudication and sciatica. All fulfilled the inclusion criteria for ACE,
i.e., suspected but not verified spinal stenosis in 1 to 3 levels. In 125 patients (50%), a significant
narrowing of the spinal canal occurred. Out of these 125 patients, 101 had a clear stenosis
besides the stenosis only detected at ACE. In 24 patients, a hidden stenosis was detected in 1 to
3 levels only at the ACE. These patients were observed for 1 to 6 years after decompression with
or without fusion regarding subjective improvement of leg and back pains, walking capacity,
satisfaction, and health related quality of life.
Results. At follow-up, 76% of the patients had leg pain less than 25/100 on a VAS scale and 62%
had back pain less than 25/100. Ninety-six percent were improved or much improved regarding
leg and back pains The ability to walk increased significantly after surgery. Walking capacity to
more than 500 m increased from 4% to 87%. Twenty-two patients were subjectively satisfied with
the surgical results. The ODI score, the SF-36 and the EQ-5D score corresponded well to the
above mentioned improvements at follow-up.
Conclusion. According to this study, the results of surgery in hidden lumbar stenosis only
detected by axial compression in extension during CT or MRI, are convincing and comparable
with the results of surgical treatment for stenoses diagnosed by unloaded examinations.
Web link to this journal
Publish Ahead of Print, published online before print, 31 January 2008
Antidepressant Treatment and Worsening White Matter on Serial Cranial Magnetic
Resonance Imaging in the Elderly: The Cardiovascular Health Study
Steffens, David C. ; Chung, Hyoju ; Krishnan, K Ranga R. ; Longstreth, W T. Jr et al
Background and Purpose-: In some studies, late life depression is associated with white matter
lesions on MRI. The effect of different classes of antidepressants on progression of white matter
lesions is unknown. Selective serotonergic reuptake inhibitors (SSRIs) may decrease platelet
aggregation. We hypothesized that Cardiovascular Health Study participants taking SSRIs would
less often have worsening white matter on serial MRI than participants not on antidepressants.
Methods-: Among 1826 participants who were not using an antidepressant at initial MRI scan, we
examined the association of worsening in white matter grade from initial to follow-up MRI scans, 5
years apart on average, and antidepressant use between the scans. Logistic regression models
were used, controlling for a variety of potential confounding variables.
Results-: Use of any antidepressant during the period of study was associated with worsening
white matter. In a multivariable model, risk was slightly increased, not reduced, with use of
serotonergic agents (OR 1.36, 95% CI 0.87 to 2.12) and was significantly increased with the use
of tricyclic antidepressants (OR 1.77, 95% CI 1.07 to 2.94).
Conclusions-: The association between worsening white matter and use of tricyclic
antidepressants was an unexpected finding that may relate to indications for use other than
depression or to side effects such as hypotension. Protection against worsening was not seen
with use of serotonergic agents.
Publish Ahead of Print, published online before print, 7 February 2008
Linking MRI Hyperintensities With Patterns of Neuropsychological Impairment: Evidence
for a Threshold Effect
Libon, David J. ; Price, Catherine C. ; Giovannetti, Tania ; Swenson, Rodney ; Bettcher, Brianne
Magouirk ; Heilman, Kenneth M. ; Pennisi, Alfio
Background and Purpose-: Leukoaraiosis (LA) might interrupt intra- and interhemispheric
communication and thus induce cognitive impairments and dementia. It remains unclear,
however, if there is a volume threshold of LA that is needed before either the signs of dementia
and/or a specific pattern of neuropsychological impairment become manifest. Roman et al has
suggested that 25% of white matter may need to be involved before white matter alterations
influence the clinical signs associated with dementia. The purpose of this study is to ascertain the
threshold of MRI-LA as measured with a visual rating scale needed to induce specific patterns of
neuropsychological impairment associated with dementia.
Methods-: One hundred fifteen patients with dementia received a comprehensive
neuropsychological examination and the severity of MRI-LA was measured using a 40-point LA
Results-: Patients were categorized into low (mean LA=4.21+/-2.92; 3.22%-17.82%), moderate
(mean LA=12.58+/-2.54; 25.01%-37.80%), and severe (mean LA=22.36+/-4.04; 45.80%-66.00%)
LA groups. Patients in the mild LA group obtained markedly lower scores on tests of episodic
memory compared with working memory, a neuropsychological profile often associated with
Alzheimer disease. Patients with moderate LA displayed equal impairment on neuropsychological
tests. Patients in the severe LA group obtained significantly lower scores on tests of working
memory as compared with episodic memory.
Conclusions-: These data provide evidence that a threshold of moderate MRI-LA as measured
with a visual rating scale is associated with greater and/or equal impairment on tests of working
memory versus episodic memory and provides a benchmark to assess the effect of MRI-LA on
the clinical presentation of dementia.
Publish Ahead of Print, published online before print, 7 February 2008
Gray Matter Atrophy in Patients With Ischemic Stroke With Cognitive Impairment.
Stebbins, Glenn T.; Nyenhuis, David L. ;Wang, Changsheng ; Cox, Jennifer L. ; Freels, Sally et al
Background and Purpose-: Patients with ischemic stroke are at risk for developing vascular
cognitive impairment ranging from mild impairments to dementia. MRI findings of infarction, white
matter hyperintensities, and global cerebral atrophy have been implicated in the development of
vascular cognitive impairment. The present study investigated regional gray matter volume
differences between patients with ischemic stroke with no cognitive impairment and those with
impairment in at least one domain of cognitive function.
Methods-: Ninety-one patients with ischemic stroke participated. Detailed neuropsychological
testing was used to characterize cognitive functioning in 7 domains: orientation, attention, working
memory, language, visuospatial ability, psychomotor speed, and memory. High-resolution T1-
weighted 3-dimensional fast-spoiled gradient recalled structural MRIs were processed using
optimized voxel-based morphometry techniques while controlling for lesions. Whole brain
voxelwise regional differences in gray matter volume were assessed between patients with stroke
with no impaired cognitive domains and patients with stroke with at least one impaired cognitive
domain. Logistic regression models were used to assess the contribution of demographic
variables, stroke-related variables, and voxel-based morphometry results to classification of
cognitive impairment group membership.
Results-: Fifty-one patients had no impairments in any cognitive domain and 40 patients were
impaired in at least one cognitive domain. Logistic regression identified significant contributions to
cognitive impairment groups for demographic variables, stroke-related variables, and cognitive
domain performance. Voxel-based morphology results demonstrated significant gray matter
volume reductions in patients with stroke with one or more cognitive domain impairment
compared with patients with stroke without cognitive impairment that was seen mostly in the
thalamus with smaller reductions found in the cingulate gyrus and frontal, temporal, parietal, and
occipital lobes. These reductions were present after controlling for group differences in age,
education, stroke volume, and laterality of stroke. The addition of voxel-based morphometry-
derived thalamic volume significantly improved a logistic regression model predicting cognitive
impairment group membership when added to demographic variables, stroke-related variables,
and cognitive domain performance.
Conclusions-: These results suggest a central role for the thalamus and lesser roles for other
cortical regions in the development of cognitive impairment after ischemic stroke. Indeed,
consideration of thalamic volumes adds significant information to the classification of cognitive
impaired versus nonimpaired groups beyond information provided by demographic, stroke-
related, and cognitive performance measures.
JOURNAL ARTICLES NOT AVAILABLE TO YOU IN FULL TEXT
Volume 51, Bonus Issue, December 2007
HEAD AND NECK
Myoepithelioma and malignant myoepithelioma arising from the salivary gland:
computed tomography and magnetic resonance findings
Y Monzen, N Fukushima and T Fukuhara
Ossifying pleomorphic adenoma of the parotid gland: A case report and review
H Kato, M Kanematsu, K Ando, K Mizuta, Y Ito, Y Hirose and H Hoshi
Cemento-ossifying fibroma of mandible
AG Hombal, KK Hegde and VN Narvekar
Rare presentation of thyroglossal duct cyst after radiation therapy to the neck
A Srinivasan, M Hayes, D Chepeha and SK Mukherji
Cervical chordoma presenting as retropharyngeal mass and dysphonia: Case report
and literature review
N Singh, M Soo, M De Cruz, L Gomes, F Maclean and G Dandie
Invasive sinus aspergillosis with perineural spread in an immunocompetent patient
S Subramanian, H Kandpal, R Sharma, N Pushkar, S Sen, S Gamanagatti and S Vashist
Oesophageal and tracheal perforation in thyroid B-cell lymphoma
JL Jaremko, B Rawat and S Naik
Lemierre’s syndrome revisited: case report and imaging findings
O Chiu, SH Erbay and RA Bhadelia
Imaging features of endolymphatic sac tumours: case report with review of literature
M Kang, N Khandelwal, P Singh, S Choudhary and KK Mukherjee
Myxoma of the masticator space
MR Gandhi, YM Tang and B Panizza
Dorsal dermal sinus with intramedullary abscess formation
JR Shah,V Joshi and D Patkar
Paradoxical cerebral arterial gas embolism: Computed tomography findings
SB Ghatge, VL Bhatgadde, AM Nagar, AA Raut and RS Narlawar
Anterior urethral value: An uncommon cause of urethral obstruction
SMA Hassam and K Tew
A child with respiratory distress having unilateral obstructive emphysema and
contralateral opaque hemithorax on chest radiograph: Role of multi-detector
computerized tomography with multi-planar reconstruction and virtual bronchoscopy
J Debnath, NK Jain, KM Adhikari, SK Shelley, A Vaidya and RA George
Brain MRI features of merosin-negative congenital muscular dystrophy
JK Ibrahim Abdulla, S Vattoth, AA Al Tawari, T Pandey and S Abubacker
Patent urachus in a neonate: Findings at micturating cystourethregram
PJ Depree and CKF Wong
Magnetic resonance imaging of a case of monomelic macrodystrophia lipomatosa
Candida prosthetic valve endocarditis: the complementary role of multidetector
computed tomography and transoesophageal echocardiography in preoperative
E Ghersin, J Lessick, Y Agmon, A Engel, A Kophit and Z Adler
Barium aspiration showing crazy-paving appearance on high-resolution computed
S Akata, J Park, H Shindo, M Yoshimura, D Kakizaki and K Abe
Tracheal bronchus misdiagnosed as tuberculosis
Nivene Saad, Merle Wigeson and Troy Stapleton
Bag of worms
B McGuinness, MC Soh, S Kumar and J Donald
Thoracic splenosis: Diagnosis of a case based on history and computerized
S McKeen and F Dharsono
Strangulated stomach within a paraoesophageal hernia: A rare complication of
laparoscopic Nissen fundoplication
J Robertson and E Avjioglu
Multidetector spiral CT venography in the diagnosis of upper extremity deep venous
R Sabharwal, D Boshell and P Vladica
Double superior vena cava with a persistent left superior vena cava: an incidental
finding during peripherally inserted central catheter placement
NK Shyamkumar and R Brown
Intramural haematoma of the oesophagus presenting as an unusual complication of
AY Wang, RD Riordan, N Yang and C-y Hiew
Pseudomesotheliomatous adenocarcinoma of the lung with synchronous gastric and
K Kaira, N Sunaga, N Yanagitani, T Hisada, T Ishizuka and M Mori
GYNAECOLOGY AND OBSTETRICS
Disseminated peritoneal leiomyomatosis: magnetic resonance imaging and differential
Endometriosis of the inguinal region: Magnetic resonance imaging (MRI) findings
RS Low, AO Jones, M Houang, L Newland, AL Morey and T Chan-Ling
Magnetic resonance imaging of pregnancy in suspected uterine anomaly
Meat balls: a pathognomonic ultrasound and computed tomography finding in mature
S Mahomedy, MR Bayat and M Seedat
Transmigrated intrauterine device discovered 17 years after its insertion
T Bartalena, E Pascali, MF Rinaldi, R Marasco, F Bassi, C Alboni and G Gavelli
Solid pseudopapillary tumor of the pancreas with portal vein compression presenting
as portal hypertension
H Kandpal, R Sharma, CJ Das, P Sahni, AK Das and Z Neyaz
Portal vein thrombosis with unusual hepatic enhancement pattern: Diagnosis using 64-
slice multidetector computed tomography and 3 Tesla magnetic resonance imaging
Herniation of the gall bladder through the abdominal wall
M Pijpers, EJ Hazebroek, PPLO Coene, H Beerman and D Vroegindeweij
Fluoromethylcholine PET in recurrent multifocal hepatoma
NP Lenzo, J Anderson, A Campbell, L Morandeau and TR De Grado
Aberrant right hepatic duct presenting as empyema of the gall bladder
B Pottakkat and SS Sikora
Celiomesenteric trunk: Two variants of a rare anomaly
JM Petscavage and P Maldjian
Multiple hepatic hemangiomas with fluid-fluid levels
J Lee, HK Lim, and YH Jeon
Intramural haematoma of the thoracic aorta: Rupture and endoluminal exclusion
AJ Spencer and TM Buckenham
Management of iatrogenic porto-biliary fistula following biliary stent
IM Chaitowitz, R Heng and KW Bell
Iatrogenic stenosis following suture-mediated closure device
J Tam, M Given, P Lutjen, K Thomson and S Lyon
Percutaneous intracorporeal lithotripsy of biliary calculi
JK Hoang, AF Little and A Clarke
Direct percutaneous portocaval shunt creation for haematemesis: Case Report
M Pianta, N Tran, M Given and SM Lyon
Emergent treatment of an Iatrogenic arterial injury at femoral puncture site With
Symbiot® self-expanding PTFE-covered coronary stent-graft
A Arat, B Turkbey, BE Cil, M Canyigit and S Cekirge
Percutaneous biliary internal decompression in a patient with simultaneous malignant
biliary and duodenal obstruction and surgically modified anatomy
MS Gulati, T Sabharwal, R Dourado and A Adam1
Emergency embolization of multiple splenic artery pseudoaneurysms associated with
portal hypertension complicating cystic fibrosis
T Geoghegan, G McAuley, A Snow and WC Torreggiani
Basilar artery aneurysm treated with coil embolization via persistent primitive
JR Bapuraj, V Ojili, N Khandelwal, AKP Shanbhogue and SK Gupta
Combined treatment of ablative therapy with percutaneous radiofrequency and
cementoplasty of a symptomatic metastatic lesion of the acetabulum
G Carrafiello, D Laganà, C Recaldini, M Mangini, A Giorgianni, S Cuffari, G Dionigi, F
D’Angelo and C Fugazzola
BRITISH JOURNAL OF RADIOLOGY
VOL 81 PART 962 2008
Summary of meeting on ``Radiobiological modelling in treatment planning' at
the BIR on 12 December 2006
Author(s): Fowler , J . F
Pelvic phased - array MR imaging of anal carcinoma before and after
Author(s): Koh , D . M . ; Dzik - Jurasz , A . ;O Neill , B . ; Tait , D . ;Husband , J . E et al
Three - dimensional CT angiography of the pancreatic artery in 16 - channel
multislice CT : value of scanning with submillimetre collimation
Author(s): Ishigaki , S . ; Itoh , S . ; Suzuki , K . ; Satake , H . ; Ota , T . ; Ikeda , M .et al
Percutaneous needle biopsy of lung nodules under CT fluoroscopic guidance
with use of the ``I - I device'
Author(s): Yoshimatsu , R . ; Yamagami , T .; Kato , T . Hirota , T . ;Matsumoto , T et al
Haemodynamic parameters of the hepatic artery and vein can detect liver
metastases : assessment using contrast - enhanced ultrasound
Author(s): Zhou , J . H . ; Li , A . H . ; Cao , L . H . ; Jiang , H . H . ; Liu , L . Z . et al
Measurement of pharmacokinetic parameters in histologically graded
invasive breast tumours using dynamic contrast - enhanced MRI
Author(s): Radjenovic , A . ; Dall , B . J . ; Ridgway , J . P . ; Smith , M . A .
A morphological index for assessing hip osteoarthritis severity from
Author(s): Boniatis , I .;Costaridou , L .;Cavouras , D .;Kalatzis , I .Panagiotopoulos , E
Biologically effective dose using reciprocal repair for varying fraction doses
and fraction intervals
Author(s): Buckle , A . H . ; Lewis , J .
Radiation therapy to non - iatrogenic subcutaneous metastasis in
hepatocellular carcinoma : results of a case series
Author(s): Huang , Y .- J . ; Tung , W - C . ; Hsu , H .- C . ; Wang , C - Y . ; Huang et al
An investigation of the shielding characteristics of computed radiography
Author(s): Potts , R . ; Baker , K . ; Bridge , L .
Ultrasound - guided thrombin injection of iatrogenic groin pseudoaneurysm :
Doppler features and technical tips
Author(s): Hanson , J . M . ; Atri , M . ; Power , N .
Article Title: Cystic neck mass in a young man
Author(s): Buckley , O . ; Hamilton , S .
JOURNAL OF MEDICAL IMAGING AND RADIATION ONCOLOGY
Volume 52, Issue 1, February 2008
A message from the Editor-in-Chief, Journal of Medical Imaging and Radiation Oncology
Lost in narration: Do we need to improve the quality of breast imaging reporting in
N Houssami L Wylie
Multidetector CT portal venography in evaluation of portosystemic collateral vessels
A Agarwal M Jain
Interventional radiology in the provision and maintenance of long-term central venous
SM Lyon, M Given NL Marshall
Lymph node enlargement in pulmonary arterial hypertension due to chronic
CJ Bergin KJ Park
Transrectal ultrasound in detecting prostate cancer compared with serum total
prostate-specific antigen levels
S Tamsel, R Killi, M Hekimgil, B Altay, S Soydan G Demirpolat
Magnetic resonance findings in women at high risk for developing breast cancer: An
Australian feasibility study
G Peters, J Anderson, G Longman, J Thomson, D Taylor, M Bennett, E Wylie, J Goldblatt, A
Chan C Saunders
Evaluation of chest wall invasion by lung cancer using respiratory dynamic MRI
S Akata, N Kajiwara, J Park, M Yoshimura, D Kakizaki, K Abe, T Hirano, T Ohira, M Tsuboi H
Abdominal cerebrospinal fluid pseudocyst: a complication of ventriculoperitoneal
shunts in adults
F Aparici-Robles R Molina-Fabrega
Magnetic resonance imaging of lipoma and atypical lipomatous tumour/well-
differentiated liposarcoma: observer performance using T1-weighted and fluid-sensitive
AJ Doyle, AK Pang, MV Miller JG French
Prevalence of significant extracoronary findings on multislice CT coronary angiography
examinations and coronary artery calcium scoring examinations
YM Law, J Huang, K Chen, FK Cheah T Chua
Follow up of coiled intracranial aneurysms with standard resolution and higher
resolution magnetic resonance angiography
S Dupre A Coulthard
Preoperative diagnosis of carcinoma within fibroadenoma on screening mammograms
N Borecky M Rickard
Saphenous vein peripherally inserted central catheters: Technique, indications and
L Du, K Redmond, S Johnstone, M De Leacy J Harper
Medulloblastomas Primitive neuroectodermal tumours in the adult population
RI Smee JR Williams
Ultrasound-based conformal planning for gynaecological brachytherapy
S van Dyk D Bernshaw
Esthesioneuroblastoma: A case report of diffuse subdural recurrence and review of
recently published studies
L Capelle H Krawitz
Bulky scalp metastasis and superior sagittal sinus thrombosis from a cervical
adenocarcinoma: An unusual case
A Abhishek, MM Ouseph, P Sharma, V Kamal M Sharma
Unusual behaviour of low-grade chondrosarcoma of bone
K Jones, J Pacella, AD Kirby N Pervez
LETTER TO THE EDITOR
Bread and butter radiology
R O’Neil, YS Wong
VOL 30 PART 1 2008
Slicetized ! As a result of the growing number of slices ( 16 , 32 , 64 , 256 ,
and now a 320 multislice CT scanner ! ) , we are encountering an explosion
Author(s): Lipcamon , J . D
Impending Staffing Shortage . . Again ? A recent study predicted a 26%
increase in the number of healthcare jobs this year .Is your facility prepared?
Author(s): Edge , R
No , I'm Sorry , You Don't Get Paid for That Either : With a less than
delightful start to the year , 2008 brings in sweeping changes for hospital
Author(s): Mulaik , M . W
Understanding the Revenue Cycle : Coordinated Billing Process Key to
Author(s): DeBlock , E
Article Title: DICOM Questions , Answered
Author(s): Oosterwijk , H
Article Title: Leadership Challenges of a Multigenerational Workforce
Author(s): Stockburger , W . T
Moments of Excellence : Whether in the workplace or on the hiking trail ,
moments of excellence are experienced and should be shared with the team
Author(s): Boyd , G
Article Title: Employee Incentives in the Healthcare Industry
Author(s): McKinnies , R . C . ; Collins , S . K . ; Collins , K . S .
Do You Have Differential Advantage ? Differential advantage is what makes
a facility unique in the marketplace . It helps create a good business
foundation and gets you on the way to marketing and financial success
Author(s): Yoder , E
Disaster Drill : If you haven't done so already , start creating a strategic plan
now to help your facility out of an unforseen disaster
Author(s): Tye , G . A