In this webinar sponsored by BIOPAC Systems and Epitel, Frazer Findlay and Mark Lehmkuhle discuss study design and demonstrate correct equipment set up and operation when recording small animal EEG. Specifically, Mr. Lehmkuhle demonstrates the application of the implantable Epoch wireless EEG/neural signal system — he reviews surgical procedure and transmitter implantation, device setup, and best-practices that will lead to successful and reproducible data collection. Following, Mr. Findlay provides a detailed demonstration in BIOPAC AcqKnowledge software, including how to set up multi-channel data acquisition, integrate video capture, interrogate EEG data and improve signal quality, complete EEG frequency analysis, and how to use important software functions (such as “Focus Areas”) for seizure detection and sleep analysis.

1. Measuring Long-Term, Wireless EEG in Rodents
using Epitel-Epoch and BIOPAC Systems
Experts discuss the fundamentals of wireless, long-term EEG
recording in small animals and present new research
capabilities enabled through the integration of technology and
physiological analysis systems.

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3. Mark Lehmkuhle, PhD
CEO/CTO
Epitel, Inc.
Implanting Epoch Transmitters and Setting Up The
Wireless Epoch Biopotential Recording System
© Epitel, Inc. 2017 www.epitelinc.com

4. Part 1:
Transmitter
Implantation
© Epitel, Inc. 2017 www.epitelinc.com
To view the video of this
section click here.
Transmitter
Implantation is covered
from 1:20 – 19:41

5. Part 2:
Hardware Setup
© Epitel, Inc. 2017 www.epitelinc.com
To view the video of this
section click here.
Hardware Setup is
covered from
19:43 – 23:58

6. Frazer Findlay
CEO
BIOPAC Systems, Inc.
Acquiring Great Data and Performing EEG
Signal Analysis in AcqKnowledge Software
BIOPAC—Inspiring people and enabling discovery about life
© BIOPAC Systems, Inc. 2017 www.biopac.com

7. BIOPAC—Inspiring people and enabling discovery about life
© BIOPAC Systems, Inc. 2017
www.biopac.com
7

8. BIOPAC—Inspiring people and enabling discovery about life
© BIOPAC Systems, Inc. 2017
www.biopac.com
8
Presentation Overview
Hardware Interface Recap
AcqKnowledge Software Setup
Multi-channel Data Acquisition
AcqKnowledge Video Capture
EEG Filtering and Data Quality
EEG Frequency Analysis
Seizure Detection
Sleep Analysis

9. BIOPAC—Inspiring people and enabling discovery about life
© BIOPAC Systems, Inc. 2017
www.biopac.com
9
Hardware Interface
MP160 System
Use the CBL123 to interface
between the Epoch
Receiver and the HLT100C
MP150 System
Use the CBL102 to
interface between the
Epoch Receiver and the
UIM100C

10. BIOPAC—Inspiring people and enabling discovery about life
© BIOPAC Systems, Inc. 2017
www.biopac.com
10
Software Demo
To view the video of
this section click here.
The complete software
demonstration is
covered from
24:00 – 49:00

11. BIOPAC—Inspiring people and enabling discovery about life
© BIOPAC Systems, Inc. 2017
www.biopac.com
11
Sleep Analysis
• Observe the quantity, quality, and
condition of sleep
• Use EEG, EMG, ECG, body temperature,
and other signals to detail various sleep
stages
• Apply automatic or manual Stage Scoring,
Hypnogram & Trend information, and
Frequency analysis.
• Output Stage Graph (quantity), Average
Spectrum (quality), and Vigilance State
Parameters (condition)

12. BIOPAC—Inspiring people and enabling discovery about life
© BIOPAC Systems, Inc. 2017
www.biopac.com
12
• Interface with MP150 & MP160 or
3rd party hardware
• Hardware setup in AcqKnowledge
• Synchronized video
• Filtering and data quality options
• Automated frequency analysis
• Seizure detection analysis
• Sleep analysis
Summary

13. BIOPAC—Inspiring people and enabling discovery about life
© BIOPAC Systems, Inc. 2017
www.biopac.com
13

14. Reusable Transmitters
 compatible with Plastics1 3-electrode systems
 can be deactivated when not in use
 can be used multiple times in multiple animals
Coming 2017

15. Transmitter Size and Lifespan
A. 6-Month  9.3 x 12.4 mm
B. 2-Month  8.5 x 9.5 mm
C. 2-Week  4.0 x 6.0 mm
A.
B.
C.

16. HardwareSchematic
For additional information, go to www.biopac.com, or email info@biopac.com

17. For additional information, go to www.biopac.com, or email info@biopac.com

18. For additional information,
go to www.biopac.com, or email info@biopac.com
Automated
EEG Analysis
 Derive EEG Frequency Bands
 Delta Power Analysis
 Derive Alpha RMS
 EEG Frequency Analysis
 Seizure Detection
 Compute Approximate
Entropy

19. Mark Lehmkuhle, PhD
CEO/CTO
Epitel, Inc.
epoch@epitelinc.com
Thank You
Frazer Findlay
CEO
BIOPAC Systems Inc.
info@biopac.com
For additional information on the products and applications presented
during this webinar please visit www.biopac.com and www.epitelinc.com