Exploratory Outcome Study of Ibogaine-Assisted Therapy in 20 Chemically-Dependent Persons Valerie Mojeiko Multidisciplinar...
Ibogaine Outcome Study, V. Mojeiko Tabernanthe Iboga
Ibogaine Outcome Study, V. Mojeiko
Ibogaine Outcome Study, V. Mojeiko
Ibogaine Outcome Study, V. Mojeiko Howard Lotsof
Subjective Effects <ul><li>Psychedelic that produces a dreamlike state </li></ul><ul><li>Review of memories </li></ul><ul>...
Neurotransmitter Activities <ul><li>Novel mechanism of action </li></ul><ul><li>Complex interactions between multiple neur...
Where do addicts take ibogaine? Ibogaine Outcome Study, V. Mojeiko
Ibogaine Outcome Study, V. Mojeiko Hotel Rooms
Ibogaine Outcome Study, V. Mojeiko At Home
Ibogaine Outcome Study, V. Mojeiko Iboga Therapy House, Canada
Ibogaine Outcome Study, V. Mojeiko
Existing treatment facilities providing detoxification--not collecting information… <ul><li>How well does it work? How saf...
Preliminary Data: June 2004: Iboga Therapy House: 2wks-1yr after tx (avg. 6 months) <ul><li>20 subjects </li></ul><ul><li>...
Exploratory  Outcome Study <ul><li>Seeking to obtain  basic  preliminary data  </li></ul><ul><li>Not  a controlled study, ...
ASI-Addiction Severity Index <ul><li>Semi-structured 1 hour interview  </li></ul><ul><li>Scores on 7 subscales: medical st...
Peak Experience Profile (PEP) <ul><li>Measures the psychedelic experience </li></ul><ul><li>180 items; one composite score...
Measures <ul><li>Addiction Severity Index (primary variable) </li></ul><ul><li>Peak Experience Profile </li></ul><ul><li>B...
Process <ul><li>All interviews are conducted by evaluation coordinator </li></ul><ul><li>Baseline in person; follow-up by ...
Ibogaine Outcome Study, V. Mojeiko Schedule for Outcome Measures i=Intake; P=Post-treatment; W2=Week 2; 1-12=Months 1-12 i...
Challenges <ul><li>No drug testing </li></ul><ul><li>Difficulty of remaining in contact during follow-up </li></ul><ul><li...
Progress <ul><li>End of protocol design and training phase </li></ul><ul><li>Began study at Ibogaine Association; ended pr...
Goals <ul><li>Obtain basic information about outcomes in underground clinics </li></ul><ul><li>Provide feedback to improve...
Upcoming SlideShare
Loading in...5
×

Ibogaine: Isreali MAPS

754
-1

Published on

Published in: Education, Technology
0 Comments
0 Likes
Statistics
Notes
  • Be the first to comment

  • Be the first to like this

No Downloads
Views
Total Views
754
On Slideshare
0
From Embeds
0
Number of Embeds
2
Actions
Shares
0
Downloads
6
Comments
0
Likes
0
Embeds 0
No embeds

No notes for slide

Ibogaine: Isreali MAPS

  1. 1. Exploratory Outcome Study of Ibogaine-Assisted Therapy in 20 Chemically-Dependent Persons Valerie Mojeiko Multidisciplinary Association for Psychedelic Studies (MAPS) www.maps.org
  2. 2. Ibogaine Outcome Study, V. Mojeiko Tabernanthe Iboga
  3. 3. Ibogaine Outcome Study, V. Mojeiko
  4. 4. Ibogaine Outcome Study, V. Mojeiko
  5. 5. Ibogaine Outcome Study, V. Mojeiko Howard Lotsof
  6. 6. Subjective Effects <ul><li>Psychedelic that produces a dreamlike state </li></ul><ul><li>Review of memories </li></ul><ul><li>Experience lasts several days </li></ul><ul><li>Many find it unpleasant, not a recreational drug </li></ul><ul><li>Some experience psychological material related to addiction </li></ul><ul><li>Greatly reduces physical and psychological withdrawal symptoms from heroin, methadone, other drugs </li></ul>Ibogaine Outcome Study, V. Mojeiko
  7. 7. Neurotransmitter Activities <ul><li>Novel mechanism of action </li></ul><ul><li>Complex interactions between multiple neurotransmitter systems </li></ul><ul><li>Mu-opiod agonist; NMDA antagonist; kappa opioid agonist; serotonin 5ht2a agonist; serotonin uptake inhibitor; 5ht3 agonist; dopamine uptake inhibitor; sigma opioid receptor agonist… </li></ul>Ibogaine Outcome Study, V. Mojeiko
  8. 8. Where do addicts take ibogaine? Ibogaine Outcome Study, V. Mojeiko
  9. 9. Ibogaine Outcome Study, V. Mojeiko Hotel Rooms
  10. 10. Ibogaine Outcome Study, V. Mojeiko At Home
  11. 11. Ibogaine Outcome Study, V. Mojeiko Iboga Therapy House, Canada
  12. 12. Ibogaine Outcome Study, V. Mojeiko
  13. 13. Existing treatment facilities providing detoxification--not collecting information… <ul><li>How well does it work? How safe is it? </li></ul><ul><li>What percentage of people benefit and to what degree? </li></ul><ul><li>How can these treatments be improved? </li></ul><ul><li>Should formal studies be conducted? </li></ul>Ibogaine Outcome Study, V. Mojeiko MAPS’ Role: Evaluating program, providing feedback, and collecting data for research
  14. 14. Preliminary Data: June 2004: Iboga Therapy House: 2wks-1yr after tx (avg. 6 months) <ul><li>20 subjects </li></ul><ul><li>6 of 7 treated for Cocaine/Crack abstinent (86%) </li></ul><ul><li>3 of 8 treated for opiates abstinent (38%) </li></ul><ul><li>4/5 treated for other substances abstinent (80%) </li></ul>Ibogaine Outcome Study, V. Mojeiko
  15. 15. Exploratory Outcome Study <ul><li>Seeking to obtain basic preliminary data </li></ul><ul><li>Not a controlled study, but is representative since including 20 Subjects treated consecutively </li></ul><ul><li>One-year series of questionnaires and interviews from 20 subjects verified by interview with significant others </li></ul><ul><li>Harm reduction model: looking at abstinence as well as non-abstinence outcomes, trying to differentiate between abuse and controlled use </li></ul>Ibogaine Outcome Study, V. Mojeiko
  16. 16. ASI-Addiction Severity Index <ul><li>Semi-structured 1 hour interview </li></ul><ul><li>Scores on 7 subscales: medical status, employment and support, drug use, alcohol use, legal status, family/social status, and psychiatric status </li></ul><ul><li>Been used extensively on a wide variety of outcome studies </li></ul>Ibogaine Outcome Study, V. Mojeiko
  17. 17. Peak Experience Profile (PEP) <ul><li>Measures the psychedelic experience </li></ul><ul><li>180 items; one composite score; 16 subscores </li></ul><ul><li>Scores for peaks (highs) and nadirs (lows) </li></ul>Ibogaine Outcome Study, V. Mojeiko
  18. 18. Measures <ul><li>Addiction Severity Index (primary variable) </li></ul><ul><li>Peak Experience Profile </li></ul><ul><li>Beck Depression and Anxiety Inventories </li></ul><ul><li>Subjective and Objective Opiate Withdrawal Scales (SOWS/OOWS) </li></ul><ul><li>Pain and Craving Scales </li></ul>Ibogaine Outcome Study, V. Mojeiko
  19. 19. Process <ul><li>All interviews are conducted by evaluation coordinator </li></ul><ul><li>Baseline in person; follow-up by phone </li></ul><ul><li>Each interview takes about an hour or two </li></ul><ul><li>Valerie organizes and analyzes data </li></ul>Ibogaine Outcome Study, V. Mojeiko
  20. 20. Ibogaine Outcome Study, V. Mojeiko Schedule for Outcome Measures i=Intake; P=Post-treatment; W2=Week 2; 1-12=Months 1-12 i P W2 1 2 3 4 5 6 7 8 9 10 11 12 ASI X X X X X X X X X X X X X BDI/BAI X X X X X X X X X X X X X X PEP X O/SOWS X X X Pain/Cra X X X X X X X X X X X X X X X SO check X X X X X X X X X X X X X X X
  21. 21. Challenges <ul><li>No drug testing </li></ul><ul><li>Difficulty of remaining in contact during follow-up </li></ul><ul><li>Check-in with significant other addresses these concerns </li></ul>Ibogaine Outcome Study, V. Mojeiko
  22. 22. Progress <ul><li>End of protocol design and training phase </li></ul><ul><li>Began study at Ibogaine Association; ended prematurely </li></ul><ul><li>Assisting Iboga Therapy House in obtaining grant from Health Canada </li></ul><ul><li>Partial funding obtained from private donors for study, Iboga Therapy House seeking additional funding for operating costs </li></ul>Ibogaine Outcome Study, V. Mojeiko
  23. 23. Goals <ul><li>Obtain basic information about outcomes in underground clinics </li></ul><ul><li>Provide feedback to improve services; help win funding from Canadian government; increase safety </li></ul><ul><li>Ideally lead to placebo-controlled double-blind studies </li></ul><ul><li>Ibogaine available to drug addicts in a safe, supportive, and humane setting </li></ul>Ibogaine Outcome Study, V. Mojeiko
  1. A particular slide catching your eye?

    Clipping is a handy way to collect important slides you want to go back to later.

×