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Ibogaine

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  • Also used as an initiation practice
  • Such as: Having a pre-existing heart condition, sometimes one not detectable by EKG Using opiates when on ibogaine, or shortly afterwards Using the rootbark or iboga extract because Ibogaine HCl is statistically much safer orTaking ibogaine outside of a clinical facility because people taking ibogaine need constant supervision and, ideally, online heart monitoring Ibogaine has also been used for psychotherapy and pain management.
  • Breaks down in the liver into a metabolite called nor-ibogaine which has been shown to prevent cravings and have anti-depressant effects that last for weeks or longerIbogaine’s effects may result from complex interactions between multiple neurotransmitter systems rather than predominant activity of a single neurotransmitter (Popik & Skolnick, 1999).
  • Each form has a different onset and duration of action and the purified ibogaine has been shown to last longer than the extract.Generally, lower doses are used for psychotherapeutic therapy and higher doses are used for detox-ingThe cost of the dose has been known to be has high as $10000. Currently, there is no funding available for the treatment in Canada.
  • 8-12hours after the last dose of heroin, morphine, demerol, crack &/or cocaine and 24 hours after the last dose of methadoneBooster dosing is not recommended unless very experienced in administration. It is recommended to wait about a week to re-dose if withdrawal symptoms persist.
  • Many patients state that it is through this cognitive evaluation that the reasons for their addiction become clear
  • Sedatives that have been used include benzodiazepines, barbiturates and melatonin Some of Ibogaine’s effects are similar to opioid withdrawal and it is important for the administrator to know the difference between the two to be able to counsel the patient and assist them if in fact they are going through withdrawal.
  • Addiction is a chronic debilitating disease and relapse is always a possibility. Ibogaine is not a “cure” and works best in conjunction with well-defined therapeutic goals, adequate preparation and monitoring and integration into existing treatment options for aftercare. Supports/resources such as returning to school, place to live, social assistance, etc… whatever they may be faced with when they leave therapyOther additional post treatment therapies can include massage therapy/bodywork, guided breathwork, reiki, exercise/stretching, art & music therapy, nutritional & recovery planning
  • Includes hypertensionConcurrent opiate/stimulant drug use could be fatal because ibogaine has been shown to enhance the effects of these drugs.Impaired function may inhibit or decrease the ability to clear Ibogaine from the bodyDrugs such as anti-epilipetics, anti-depressants, etc…
  • Show video!!!! http://www.veoh.com/videos/v927524wxpsC5nkTurn PP over and then ask Q & A!
  • West AfricaAnyone without the contraindications such as impaired liver, kidney, GI function, heart disease/complications, active psycho or neurological disorders, depression, etc…24-36 hours1). Reduction of withdrawal symptoms & cravings & sustained periods of abstinence or reduced use2).Produces a subjective experience where the person may undergo processes where their life & choices are examined & reassessed3 forms: total alkaloid extract, rootbark, and purified ibogaineHClTaken orallyMonitor blood pressure and pulse every 30 minutes for first 4-8 hours or until stable and then every hour thereafter and be there to counsel the patient if needed

Transcript

  • 1. Ibogaine
    Presented by Rachel Jordan
  • 2. What is Ibogaine?
    A naturally occurring psychoactive plant alkaloid
    It is sourced from the roots of the plant TabernantheIboga that grows in the forests of West Africa
    TabernantheIboga plant
  • 3. Ibogaine’s History
    Traditionally used for thousands of years as a catalyst for spiritual exploration and healing by the African Bwiti culture.
  • 4. Ibogaine’s History
    Howard S. Lotsof first discovered Ibogaine’s ability to disrupt chemical dependency in 1962-63
    Ever since, he has been researching everything about it and advocating for it’s use in treating addiction
    As of March 2007, 12 people out of 3611 died in relation to Ibogaine treatment but also in relation to other factors
    Has been used to treat chemical dependence for over 40 years and has a 65% abstinence rate over 10% with conventional drug treatment programs
    No potential for abuse
  • 5. Ibogaine’s action
    • Has been shown to bind with multiple
    neurotransmitter sites within the CNS
    • Increases serotonin and decreases/blocks
    dopamine
    • Has been shown to act both as an
    antagonist and an agonist as well as
    directly and indirectly
  • 6. Ibogaine’s Effects
    Works in two ways:
    Reduction of withdrawal symptoms & cravings & sustained periods of abstinence or reduced use
    Produces a subjective experience where the person may undergo processes where their life & choices are examined & reassessed
  • 7. Forms and Dosage
    Botanical root bark
    Total alkaloid extract
    Purified Ibogaine HCl (99.4% purity)
    Doses are determined on an individual patient basis and are based on kg as well as addiction severity. Normal dosing is usually 15-20mg/kg for full therapeutic effect
    Cost is roughly $4700-$4900 for 5 day treatment program on Vancouver Island
  • 8. Ibogaine Administration
    An oral capsule
    Takes approx. 45 minutes to take effect & decrease withdrawal symptoms
    Should be taken in place of next narcotic dose
    Blood pressure & pulse should be checked every 30 min for first 4-8 hours & then if stable, every hour thereafter
    Effects occur in 3 stages and can last up to 36 hours
  • 9. First Stage
    Patient will usually want to lay prone & still as may experience motion related N&V
    Skin tends to become numb
    May hear an initial buzzing or oscillating sound
    A period of dream-like visualization may last for 3 to 4 hours & ends abruptly should it occur at all
    May experience random flashes of light that appear everywhere with eyes open & may last for hours or days. Visualization on the other hand is most common with eyes closed.
  • 10. Second stage
    Follows visualization & has been described as one in which the patient principally experiences cognitive evaluation or a review of issues that are important to them
    They may cover every possible scenario from early childhood experiences to current health issues & may last for as few as 8 hours or for 20 hours or longer.
  • 11. Third Stage
    Also known as Residual Stimulation stage
    It tends to leave the patient exhausted & therefore is somewhat uncomfortable
    May remain awake for two or more days but most patients will sleep within 24-48 hours of Ibogaine administration
    Usually, there is a long term diminishment of the need for sleep over weeks or months
    Some patients may require or request sedation
  • 12. Side Effects
    Coordination disturbances (unstable gait and tendency to fall)
    Hallucination-like experiences
    Sleep disturbances
    Concentration & speech troubles
    Heart rate & blood pressure changes
    Nausea & vomiting
    Dizziness
    Light sensitivity
    Tiredness
    Muscles soreness
  • 13. Post Ibogaine Treatment Therapy
    Patients are encouraged to attend NA or AA meetings for further support
    Many are encouraged to have supports &/or resources in place before detox-ing
    Other additional treatment therapies
  • 14. Contraindications
    History of heart attacks or cardiovascular disease/abnormalities
    Concurrent opiate/stimulant drug use
    Active psychological or neurological disorders
    Beck Depression Inventory score > 24
    Active TB or pregnancy
    Impaired kidney, liver or GI function
    Concurrent drugs that may cause adverse ibogaine/drug interactions
  • 15. PHN Role
    Know use/effects of Ibogaine in case a client inquires about it or presents themselves on it
    Advocate for its use/funding in addictions treatment through a harm reduction, health promotion perspective
    Educate the public and patients on benefits & risks of Ibogaine compared to conventional treatments so they can make the best choice possible & can advocate for themselves & others
    Know difference b/w opioid withdrawal & Ibogaine’s effects
  • 16. Q & A !!
    Where does Ibogaine originate from?
    Who qualifies for Ibogaine treatment?
    How long does the therapy typically last?
    What are the two main ways that Ibogaine works on treating chemical dependence?
    How many different forms are there?
    How is it typically taken?
    What should a nurse do while taking care of a person on Ibogaine?
  • 17. References
    Ibogaine Association. (2006). Retrieved February 27, 2008 from http://www.ibogaine-therapy.net/
    Ibogaine Research Project. (2005). Retrieved February 27, 2008 from http://www.ibogaine-research.org/Ibogaine-Research-Project/Ibogaine.html
    Ibogaine Roots of Hope: CBS. Retrived from Veoh videos and internet television athttp://www.veoh.com/videos/v927524wxpsC5nk
    Ibogaine Therapy House. (2008). Retrieved February 27, 2008 from http://www.ibogatherapyhouse.net/cms/content/view/22/37/
    Multidisciplinary Association for Psychedelic Studies. (2007). Ibogaine studies and research projects. Retrieved February 27, 2008 from http://www.maps.org/ibogaine/
    Roslin, A. (2007, Oct. 25). THE QUEST FOR THE ULTIMATE CURE FOR ADDICTION.The Georgia Straight. Retrieved February 27th, 2008 from http://www.mapinc.org/drugnews/v07/n1235/a06.html.
    The Ibogaine Dossier. (1999). Retrieved February 27, 2008 from http://www.ibogaine.org/index.html/