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CRO 
QUALITY 
BENCHMARKING 
PRECLINICAL 
CRO Quality 
Benchmarking – 
Preclinical Service 
Providers 
Info@ISRreports.com 
©2014 Industry Standard Research www.ISRreports.com 
PREVIEW
Report Structure: 
Service Encounters 1. Outsourcing Behaviors, Attitudes, Beliefs, and Intentions 
www.ISRreports.com ©2014 | Preview of: CRO Quality Benchmarking – Preclinical Service Providers 2 
act with confidence 
Report Overview 
ISR knows that selecting a CRO is not easy. There are a myriad of factors to evaluate for each CRO being 
considered. Does the provider have the necessary therapeutic expertise? Will the project be completed 
on time and within budget? Will the provider have sufficient access to necessary resources? Without prior 
experience with a provider, purchasers of CRO services are often forced to rely on incomplete or biased 
assessments of CRO performance passed on through word of mouth from peers within the industry. 
In this Benchmarking report, ISR provides the data necessary to answer these questions – and many 
more – with confidence. 101 decision-makers have weighed in with their Preclinical CRO selection 
criteria and outsourcing behaviors. They have provided feedback on 446 recent service encounters 
across 42 Preclinical CROs. 18 providers have received detailed service quality profiles. 
446 
101 
Respondents 
333 
Charts and Graphs 
176 
Pages 
• Preclinical Leaders 
• Proposal Volume 
• Service Provider Usage 
• Service Provider Preference 
• Service Provider Cost Experience and Perceptions 
2. Service Provider Selection Drivers 
• Most Important Service Provider Attributes 
• Service Provider Attributes Gaining Importance 
3. Service Provider Performance and Scorecards Across Attributes 
• Staff Characteristics Ratings 
• Operational Excellence Ratings 
• Organizational and Finance Ratings 
• Performance Summary by Category 
• Service Provider Loyalty 
4. Service Provider Service Quality Profiles 
5. All Study Data 
How you can use this report: 
Study Sponsors 
• Make a more informed purchase of Preclinical 
services by understanding which service 
providers best fit your company’s needs 
• Broaden your Preclinical CRO evaluation list 
by accessing peer-based service quality ratings 
across critical attributes 
• Pinpoint potential delivery concerns early 
in a CRO relationship/ evaluation in order 
to develop proactive strategies to address 
potential gaps 
Preclinical Service Providers 
• Uncover your own — and competitor — 
delivery strengths and weaknesses 
• Design messaging to tout your company’s 
strengths 
• Compete more effectively by understanding 
buyers’ selection criteria and outsourcing 
trends
CROs Included in this Report 
• Absorption Systems 
• Accelera 
• Alliance Pharma Inc. 
• Aptiv Solutions 
• Aptuit 
• Avanza Laboratories 
• BASi 
• BioDuro 
• BioReliance 
• BRI Biopharmaceutical 
• CeeTox 
• Cellular Technology Limited 
• CiToxLab 
• Covance 
• EMD Millipore 
• Frontage Laboratories 
• Harlan 
• Huntington Life Sciences 
• IITRI 
• Indivumed GmbH 
• Maccine 
• MD Biosciences 
• MDS Pharma 
• MicroConstants 
• MPI Research 
• Myriad RBM 
• Quotient BioResearch 
Participant Job Title Participant Geography Participant Company Size 
34% Europe 
www.ISRreports.com ©2014 | Preview of: CRO Quality Benchmarking – Preclinical Service Providers 3 
act with confidence 
Research Calvert 
(CTL) 
• Charles River Laboratories 
Service Quality Metrics 
• Ricerca 
• Sequani 
• Sirius Analytical 
• SNBL 
• Southern Research 
• SRI International, Biosciences 
Division 
• Taconic 
• Toxicon 
• Wil Research 
• William Harvey Research 
• WuXi AppTec 
• XenoBiotic Laboratories 
• XenoTech 
11% C-level 
13% President/ VP 
53% Director 
23% Manager 
45% Large Companies 
(R&D $1B or more) 
33% Mid-Size 
Companies (R&D 
$100M-$999M) 
28% Small Companies 
(R&D less than $100M) 
61% 
North America 
5% 
Asia / 
Other 
Report Metrics 
Respondent Demographics (N=101) 
Participant Experience: Mean = 15.5 years 
• Experience of the 
Preclinical unit’s lead 
investigator 
• Local market / Regulatory 
knowledge 
• Project manager quality 
• Project team chemistry 
• Provider responsiveness to 
sponsor’s questions 
• Scientific knowledge 
• Therapeutic expertise 
• Access to “unique” tests, 
machines, equipment 
• Data quality metrics 
• Detailed plan for timely 
project communications 
• Experience conducting 
specific tests and assays 
• Metrics for database lock 
timelines 
• Metrics for meeting overall 
project timelines 
• Offers innovative solutions 
• Prior positive experience 
with service provider 
• Technology for real-time 
access to data 
• Up-front contingency 
planning, risk management 
• Financial strength/ stability 
• Location of Preclinical 
unit(s) in different global 
regions 
• Location of Preclinical 
unit(s) within your country 
• Low cost 
• Staff turnover metrics
www.ISRreports.com ©2014 | Preview of: CRO Quality Benchmarking – Preclinical Service Providers 4 
act with confidence 
Table of Contents 
For full table of contents and additional sample pages, download the full pre-view 
from: www.isrreports.com/product/cro-quality-benchmarking-preclini-cal- 
service-providers/
Introduction 
Welcome to ISR’s CRO Quality Benchmarking Preclinical Service Providers report. 
Over time, Industry Standard Research has accumulated a wealth of knowledge 
around service quality and CRO performance. Understanding and utilizing this 
information allows stakeholders within the industry to make informed decisions 
when choosing a CRO for Preclinical services. 
ISR knows that selecting a CRO is not easy. There are a myriad of factors to 
evaluate for each CRO being considered. Does the provider have the necessary 
therapeutic expertise? Will the project be completed on time and within budget? 
Will the provider have sufficient access to necessary resources? Without prior 
experience with a provider, purchasers of CRO services are often forced to rely on 
incomplete or biased assessments of CRO performance passed on through word 
of mouth from peers within the industry. 
In this Benchmarking report, ISR provides the data necessary to answer these 
questions – and many more – with confidence. 101 decision-makers have weighed 
in with their Preclinical CRO selection criteria and outsourcing behaviors. They 
have provided feedback on 446 recent service encounters across 42 Preclinical 
CROs. 18 providers have received detailed service quality profiles. 
Not only does this report enable more educated purchases of Preclinical CRO 
services, it also allows Preclinical service providers to get a behind-the-scenes 
look at customers’ perceptions of their performance. Providers can determine 
areas of strength and understand where they may need to close the gap relative 
to competitors. As they say, knowledge is power. Having a grasp on customer 
beliefs, attitudes, and experiences will help Preclinical CROs effectively promote 
strengths and improve areas of weakness. 
www.ISRreports.com ©2014 | Preview of: CRO Quality Benchmarking – Preclinical Service Providers 5 
act with confidence 
act with confidence 
Introduction 
www.ISRreports.com ©2014 | CRO Quality Benchmarking Preclinical Service Providers 7 
Sample Page
Sample Page 
Figure 1 – Staff Characteristics Ratings 
Figure 1 – Staff Characteristics 
Ratings 
Scientific 
knowledge 
Local 
market / 
Regulatory 
knowledge 
Sta Characteristics 
Project 
team 
chemistry 
Project 
manager 
quality 
Provider 
responsiveness 
to sponsor’s 
questions 
Therapeutic 
expertise 
Experience of 
the Preclinical 
unit’s lead 
investigator 
Ratings Key: Clear leadership Better than most About average Falling a bit short Likely deficiency 
www.ISRreports.com ©2014 | Preview of: CRO Quality Benchmarking – Preclinical Service Providers 6 
act with confidence 
act with confidence 
Service Provider Performance and Scorecards Across Attributes 
www.ISRreports.com ©2014 | CRO Quality Benchmarking Preclinical Service Providers 29 
Company A 
Company B 
Absorption Systems 
Company C 
Aptiv Solutions 
Company D 
Aptuit 
Company E 
Company F 
BioReliance 
Charles River Laboratories 
Company G 
Company H 
CiToxLab 
Company I 
Covance 
Company J 
EMD Millipore 
Company K 
Frontage Laboratories Inc. 
Company L 
Harlan 
Company M 
Huntington Life Sciences 
Company N 
MDS Pharma 
Company O 
MPI Research 
Company P 
Myriad RBM 
Company Q 
Quotient BioResearch 
Company R 
Ricerca 
Wuxi Apptech 
XenoTech 
Scientific 
knowledge 
Local 
market / 
Regulatory 
knowledge 
Project 
team 
chemistry 
Project 
manager 
quality 
Provider 
responsiveness 
to sponsor’s 
questions 
Therapeutic 
expertise 
Experience of 
the Preclinical 
unit’s lead 
investigator 
Sta‚ Characteristics 
Ratings Key: Clear leadership Better than most About average Falling a bit short Likely deficiency
www.ISRreports.com ©2014 | Preview of: CRO Quality Benchmarking – Preclinical Service Providers 7 
act with confidence 
Sample Page 
For full table of contents and additional sample pages, download the full pre-view 
from: www.isrreports.com/product/cro-quality-benchmarking-preclini-cal- 
service-providers/
For pricing and ordering information, visit ISR’s website: www.isrreports.com/ 
product/cro-quality-benchmarking-preclinical-service-providers/ 
Save on this, 
or any ISR 
report, by 
registering a 
free account 
Register now 
• Receive a $250 instant credit towards any ISR report 
• Earn 10% credit towards all future purchases 
• Receive advanced notifications on ISR’s latest reports and free resources 
About Industry Standard Research 
www.ISRreports.com ©2014 | Preview of: CRO Quality Benchmarking – Preclinical Service Providers 8 
act with confidence 
Ordering Information 
Industry Standard Research (ISR) is the premier, full service market research provider to the pharma and pharma services 
industries. With over a decade of experience in the industry, ISR delivers an unmatched level of domain expertise. 
For more information about our off-the-shelf intelligence and custom research offerings, please visit our Web site at 
www.ISRreports.com, email info@ISRreports.com, or follow us on twitter @ISRreports.
The ISR Difference 
Custom-quality syndicated market research 
www.ISRreports.com 
vs. Syndicated Report 
ISR's Reports The Common 
How confident are you? 
Research methods 
Data Collection 
vs. 
Respondents 
Sample Sizes 
Analysts 
www.ISRreports.com ©2014 | Preview of: CRO Quality Benchmarking – Preclinical Service Providers 9 
act with confidence 
www.ISRreports.com ©2013 | Preview of: Benchmarking the Pharma Industry’s HEOR Functions 9 
www.ISRreports.com ©2014 | Preview of: Benchmarking European Investigator Payments 10 
www.ISRreports.com ©2013 | Preview of: Benchmarking the Pharma Industry’s HEOR Functions ISR's proprietary data collection 
tools and channels support fast, 
high quality data collection 
Struggle to recruit the right 
targets and enough of them 
vs. 
Robust sample sizes that 
instill confidence 
Often insufficient industry 
representation that leaves you 
defending results 
vvss.. 
Mostly primary 
research; 
always appropriate 
for the topic 
One size fits all; 
usually publically 
available data 
vvss.. 
Sophisticated screening 
ensures genuine 
decision-makers 
Undisclosed 
methodologies and 
respondent demographics 
vvss.. 
Decades of experience 
means more insights that are 
immediately usable 
Junior analysts capable of 
reporting numbers

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CRO Quality Benchmarking – Preclinical Service Providers

  • 1. CRO QUALITY BENCHMARKING PRECLINICAL CRO Quality Benchmarking – Preclinical Service Providers Info@ISRreports.com ©2014 Industry Standard Research www.ISRreports.com PREVIEW
  • 2. Report Structure: Service Encounters 1. Outsourcing Behaviors, Attitudes, Beliefs, and Intentions www.ISRreports.com ©2014 | Preview of: CRO Quality Benchmarking – Preclinical Service Providers 2 act with confidence Report Overview ISR knows that selecting a CRO is not easy. There are a myriad of factors to evaluate for each CRO being considered. Does the provider have the necessary therapeutic expertise? Will the project be completed on time and within budget? Will the provider have sufficient access to necessary resources? Without prior experience with a provider, purchasers of CRO services are often forced to rely on incomplete or biased assessments of CRO performance passed on through word of mouth from peers within the industry. In this Benchmarking report, ISR provides the data necessary to answer these questions – and many more – with confidence. 101 decision-makers have weighed in with their Preclinical CRO selection criteria and outsourcing behaviors. They have provided feedback on 446 recent service encounters across 42 Preclinical CROs. 18 providers have received detailed service quality profiles. 446 101 Respondents 333 Charts and Graphs 176 Pages • Preclinical Leaders • Proposal Volume • Service Provider Usage • Service Provider Preference • Service Provider Cost Experience and Perceptions 2. Service Provider Selection Drivers • Most Important Service Provider Attributes • Service Provider Attributes Gaining Importance 3. Service Provider Performance and Scorecards Across Attributes • Staff Characteristics Ratings • Operational Excellence Ratings • Organizational and Finance Ratings • Performance Summary by Category • Service Provider Loyalty 4. Service Provider Service Quality Profiles 5. All Study Data How you can use this report: Study Sponsors • Make a more informed purchase of Preclinical services by understanding which service providers best fit your company’s needs • Broaden your Preclinical CRO evaluation list by accessing peer-based service quality ratings across critical attributes • Pinpoint potential delivery concerns early in a CRO relationship/ evaluation in order to develop proactive strategies to address potential gaps Preclinical Service Providers • Uncover your own — and competitor — delivery strengths and weaknesses • Design messaging to tout your company’s strengths • Compete more effectively by understanding buyers’ selection criteria and outsourcing trends
  • 3. CROs Included in this Report • Absorption Systems • Accelera • Alliance Pharma Inc. • Aptiv Solutions • Aptuit • Avanza Laboratories • BASi • BioDuro • BioReliance • BRI Biopharmaceutical • CeeTox • Cellular Technology Limited • CiToxLab • Covance • EMD Millipore • Frontage Laboratories • Harlan • Huntington Life Sciences • IITRI • Indivumed GmbH • Maccine • MD Biosciences • MDS Pharma • MicroConstants • MPI Research • Myriad RBM • Quotient BioResearch Participant Job Title Participant Geography Participant Company Size 34% Europe www.ISRreports.com ©2014 | Preview of: CRO Quality Benchmarking – Preclinical Service Providers 3 act with confidence Research Calvert (CTL) • Charles River Laboratories Service Quality Metrics • Ricerca • Sequani • Sirius Analytical • SNBL • Southern Research • SRI International, Biosciences Division • Taconic • Toxicon • Wil Research • William Harvey Research • WuXi AppTec • XenoBiotic Laboratories • XenoTech 11% C-level 13% President/ VP 53% Director 23% Manager 45% Large Companies (R&D $1B or more) 33% Mid-Size Companies (R&D $100M-$999M) 28% Small Companies (R&D less than $100M) 61% North America 5% Asia / Other Report Metrics Respondent Demographics (N=101) Participant Experience: Mean = 15.5 years • Experience of the Preclinical unit’s lead investigator • Local market / Regulatory knowledge • Project manager quality • Project team chemistry • Provider responsiveness to sponsor’s questions • Scientific knowledge • Therapeutic expertise • Access to “unique” tests, machines, equipment • Data quality metrics • Detailed plan for timely project communications • Experience conducting specific tests and assays • Metrics for database lock timelines • Metrics for meeting overall project timelines • Offers innovative solutions • Prior positive experience with service provider • Technology for real-time access to data • Up-front contingency planning, risk management • Financial strength/ stability • Location of Preclinical unit(s) in different global regions • Location of Preclinical unit(s) within your country • Low cost • Staff turnover metrics
  • 4. www.ISRreports.com ©2014 | Preview of: CRO Quality Benchmarking – Preclinical Service Providers 4 act with confidence Table of Contents For full table of contents and additional sample pages, download the full pre-view from: www.isrreports.com/product/cro-quality-benchmarking-preclini-cal- service-providers/
  • 5. Introduction Welcome to ISR’s CRO Quality Benchmarking Preclinical Service Providers report. Over time, Industry Standard Research has accumulated a wealth of knowledge around service quality and CRO performance. Understanding and utilizing this information allows stakeholders within the industry to make informed decisions when choosing a CRO for Preclinical services. ISR knows that selecting a CRO is not easy. There are a myriad of factors to evaluate for each CRO being considered. Does the provider have the necessary therapeutic expertise? Will the project be completed on time and within budget? Will the provider have sufficient access to necessary resources? Without prior experience with a provider, purchasers of CRO services are often forced to rely on incomplete or biased assessments of CRO performance passed on through word of mouth from peers within the industry. In this Benchmarking report, ISR provides the data necessary to answer these questions – and many more – with confidence. 101 decision-makers have weighed in with their Preclinical CRO selection criteria and outsourcing behaviors. They have provided feedback on 446 recent service encounters across 42 Preclinical CROs. 18 providers have received detailed service quality profiles. Not only does this report enable more educated purchases of Preclinical CRO services, it also allows Preclinical service providers to get a behind-the-scenes look at customers’ perceptions of their performance. Providers can determine areas of strength and understand where they may need to close the gap relative to competitors. As they say, knowledge is power. Having a grasp on customer beliefs, attitudes, and experiences will help Preclinical CROs effectively promote strengths and improve areas of weakness. www.ISRreports.com ©2014 | Preview of: CRO Quality Benchmarking – Preclinical Service Providers 5 act with confidence act with confidence Introduction www.ISRreports.com ©2014 | CRO Quality Benchmarking Preclinical Service Providers 7 Sample Page
  • 6. Sample Page Figure 1 – Staff Characteristics Ratings Figure 1 – Staff Characteristics Ratings Scientific knowledge Local market / Regulatory knowledge Sta Characteristics Project team chemistry Project manager quality Provider responsiveness to sponsor’s questions Therapeutic expertise Experience of the Preclinical unit’s lead investigator Ratings Key: Clear leadership Better than most About average Falling a bit short Likely deficiency www.ISRreports.com ©2014 | Preview of: CRO Quality Benchmarking – Preclinical Service Providers 6 act with confidence act with confidence Service Provider Performance and Scorecards Across Attributes www.ISRreports.com ©2014 | CRO Quality Benchmarking Preclinical Service Providers 29 Company A Company B Absorption Systems Company C Aptiv Solutions Company D Aptuit Company E Company F BioReliance Charles River Laboratories Company G Company H CiToxLab Company I Covance Company J EMD Millipore Company K Frontage Laboratories Inc. Company L Harlan Company M Huntington Life Sciences Company N MDS Pharma Company O MPI Research Company P Myriad RBM Company Q Quotient BioResearch Company R Ricerca Wuxi Apptech XenoTech Scientific knowledge Local market / Regulatory knowledge Project team chemistry Project manager quality Provider responsiveness to sponsor’s questions Therapeutic expertise Experience of the Preclinical unit’s lead investigator Sta‚ Characteristics Ratings Key: Clear leadership Better than most About average Falling a bit short Likely deficiency
  • 7. www.ISRreports.com ©2014 | Preview of: CRO Quality Benchmarking – Preclinical Service Providers 7 act with confidence Sample Page For full table of contents and additional sample pages, download the full pre-view from: www.isrreports.com/product/cro-quality-benchmarking-preclini-cal- service-providers/
  • 8. For pricing and ordering information, visit ISR’s website: www.isrreports.com/ product/cro-quality-benchmarking-preclinical-service-providers/ Save on this, or any ISR report, by registering a free account Register now • Receive a $250 instant credit towards any ISR report • Earn 10% credit towards all future purchases • Receive advanced notifications on ISR’s latest reports and free resources About Industry Standard Research www.ISRreports.com ©2014 | Preview of: CRO Quality Benchmarking – Preclinical Service Providers 8 act with confidence Ordering Information Industry Standard Research (ISR) is the premier, full service market research provider to the pharma and pharma services industries. With over a decade of experience in the industry, ISR delivers an unmatched level of domain expertise. For more information about our off-the-shelf intelligence and custom research offerings, please visit our Web site at www.ISRreports.com, email info@ISRreports.com, or follow us on twitter @ISRreports.
  • 9. The ISR Difference Custom-quality syndicated market research www.ISRreports.com vs. Syndicated Report ISR's Reports The Common How confident are you? Research methods Data Collection vs. Respondents Sample Sizes Analysts www.ISRreports.com ©2014 | Preview of: CRO Quality Benchmarking – Preclinical Service Providers 9 act with confidence www.ISRreports.com ©2013 | Preview of: Benchmarking the Pharma Industry’s HEOR Functions 9 www.ISRreports.com ©2014 | Preview of: Benchmarking European Investigator Payments 10 www.ISRreports.com ©2013 | Preview of: Benchmarking the Pharma Industry’s HEOR Functions ISR's proprietary data collection tools and channels support fast, high quality data collection Struggle to recruit the right targets and enough of them vs. Robust sample sizes that instill confidence Often insufficient industry representation that leaves you defending results vvss.. Mostly primary research; always appropriate for the topic One size fits all; usually publically available data vvss.. Sophisticated screening ensures genuine decision-makers Undisclosed methodologies and respondent demographics vvss.. Decades of experience means more insights that are immediately usable Junior analysts capable of reporting numbers