Bladder Cancer: profile and drug development
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Bladder Cancer: profile and drug development

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ISR explores risk factors, treatment options, and future development in this infographic.

ISR explores risk factors, treatment options, and future development in this infographic.

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Bladder Cancer: profile and drug development Infographic Transcript

  • 1. Bladder Cancerprofile and drug development www.ISRreports.com Bladder Cancer is the 9th most common cancer worldwide, with about 430,000 diagnosed each year. That’s equivalent to the population of Raleigh, NC Bladder Cancer forms in the layers of the bladder wall, most commonly the innermost urothelium layer. The cancer is described and treated based on how far it has moved into the wall of the bladder. 9 out of 10 people with bladder cancer are over the age of 55 smoking workplace exposure to carcinogens race ethnicity age gender chronic bladder infection genetics other urothelial cancers hematuria frequent urination urgency irritation during urination general advanced inability to urinate lower back pain loss of appetite weight loss foot swelling bone pain Finding bladder cancer early increases the chance of successful treatment. Screening tests include urinalysis, urine cytocology, and urine tests for tumor markers. There are currently 110 active studies with bladder cancer. Surgery is used in nearly all cases of bladder cancer, and is often combined with other types of treatment including: intravesical therapy, chemotherapy, and radition therapy. After surgery, new cancers can form in the bladder over time. The only way to avoid this is a radical cystectomy, or removal of the bladder, which can have major side effects. Therapies in development for the treatment of bladder cancer include: -Angiogenesis inhibition -Growth factor inhibitors -Immunotherapeutics -Gene therapy INFO@ISRREPORTS.COM @ISRREPORTS ISRREPORTS.COM What is Bladder Cancer? Risk Factors Symptoms Treatment colorectal: 64% pancreatic: 6% bladder: 77% breast: 89% lung: 16% by stage Stage I: 88% Stage II: 63% Stage III: 46% Stage IV: 15% Future The molecular pathogenesis of bladder cancer is increasingly well understood, but translation of this knowledge into effective biomarkers and therapies has been largely unsuccessful. Learn more about therapies in active development in ISR’s “Bladder Cancer Disease and Pipeline Analysis Report” Sources:ISR Reports, seer.cancer.gov, cancer.org