• Save
Short and long term results of gastric bypass
Upcoming SlideShare
Loading in...5
×
 

Short and long term results of gastric bypass

on

  • 1,515 views

 

Statistics

Views

Total Views
1,515
Views on SlideShare
1,515
Embed Views
0

Actions

Likes
1
Downloads
0
Comments
0

0 Embeds 0

No embeds

Accessibility

Categories

Upload Details

Uploaded via as Microsoft PowerPoint

Usage Rights

© All Rights Reserved

Report content

Flagged as inappropriate Flag as inappropriate
Flag as inappropriate

Select your reason for flagging this presentation as inappropriate.

Cancel
  • Full Name Full Name Comment goes here.
    Are you sure you want to
    Your message goes here
    Processing…
Post Comment
Edit your comment

Short and long term results of gastric bypass Short and long term results of gastric bypass Presentation Transcript

  • Short and Long-Term Results of Gastric Bypass
    Samer G. Mattar, MD, FRCS, FACS
    Associate Professor of Surgery
    Indiana University
  • BOLD
    57,918 patients
    > 800 surgeons in > 450 facilities.
    31,668 patients (54.7%) had gastric bypass.
    Complication rate = 14.9%
    All mortality rate = 0.14%
    DeMaria EJ et al. SurgObesRelDis 2010;6(4):347-55
  • Long-Term Weight Loss for Gastric Bypass
    Mean BMI: 52
    Follow-up >90%
    Nadir Wt. Loss: 65% EWL
    Mean Wt. Loss at 14 years: 49% EWL
  • COMPARISON OF BARIATRIC OPERATIONS
    n = 22,094 patients; 2738 citations 1990-2002
    Buchwald, et al JAMA 2004;292:1724-1737
    Brethauer et al. SOARD 2009 (4): 469-475
  • LONG-TERM SURVIVAL CANADA
    Rel. Risk = 0.11 (.04-.27)
    89% reduction in risk ofdeath over 5 years
    Christou et al. Ann Surg 2004;240:416-424
  • Results:Five Year Comorbidity
    *
    *
    *
    *
    *
    *p<0.001
    Christou et al. Ann Surg 2004;240:416-424
  • Results:Five Year Comorbidity
    *
    *
    *
    Christou et al. Ann Surg 2004;240:416-424
  • Swedish Obese Subjects Study SOS
    Prospective matched controlled study.
    641 surgically treated subjects and 627 obese controls.
    10 year follow up.
    Surgical therapies consisted of:
    - fixed or variable banding
    - vertical banded gastroplasty
    - gastric bypass
    Sjostrom et al, NEJM 2004; 351(26): 2683-93
  • 10 years results of Bariatric Surgery
    n=1268 (641 surgery)
    Sjöström et al. N Eng J M Dec 2004;351(26):2751-3
  • EFFECT OF GBP ONTYPE 2 DIABETES MELLITUS*
    Before After Operation Operation
    Glucose Impaired 53 0
    Type 2 Diabetes 88 2
    Receiving Insulin 20 10
    Oral Agent 13 0
    Pories WJ et al. Ann Surg 1995;222:339-50
  • Observations in DM2
    Early surgical intervention is the most effective treatment for T2DM
    Results in significant reduction in medication requirement
    Resolution dependent on preoperative duration and severity of T2DM, and on ultimate weight loss
  • Conclusions
    Gastric bypass continues to be the dominant weight loss operation in the US.
    Center of Excellent data demonstrates a morbidity rate of 14% and an overall mortality rate of 0.14%.
    The effects of gastric bypass are durable.
    Gastric bypass results in 89% reduction in risk of early death.
    Early surgical intervention is the most effective treatment for DM2
  • Thank you!