Things you want to know aboutParkinsons DiseaseDr. Charulata SankhlaConsultant NeurophysicianHinduja Hospital, Mumbai
What Is Parkinsons Disease (PD)?• A brain disorder that causes agradual loss of muscle control• Symptoms of PD tend to bem...
James Parkinson 1817“Involuntary tremulousmotion, with lessenedmuscular power, in partnot in action and evenwhen supported...
Progression of the disease• While Parkinsons can be afrightening diagnosis, life expectancydoes not change particularly wi...
Early Signs of this diseaseIt may be subtle and can be confused with otherconditions. They include:• Mild shaking of a fin...
Tremor• It is an early symptom and isseen in about 70% of patients• Usually occurs in a finger orhand when the hand is at ...
Bradykinesia• As we grow older, we slow down. bradykinesia inPD patients mean slow movement which impairsdaily activities•...
Impaired Balance• These patients have difficulty in turning swiftly• They tend to develop a stooped posture, withdrooping ...
Rigidity• Rigidity means stiff muscles which dont relax• It is difficult to move patients arms and legspassively , there i...
Non motor symptoms• Night terrors, Restless sleep• Daytime fatigue• Constipation• Increase tendency to pass urine particul...
Can I get PD?• The average age of onset is 55 as one gets olderthe chances increase• Having a family member with PD slight...
What happens in Brain?• A small area in the brain stem called thesubstantia nigra produces dopamine, a chemicalthat contro...
DAT SCAN
Various strategies in treatment of PD• Multidisciplinary approach• Medical• Surgery• Physiotherapy• Occupational therapy t...
Drugs in PD• Levodopa preparations.• Dopamine receptor agonists.• Monoamine oxidase-B inhibitors.• Catechol-o-methyltransf...
Deep Brain Stimulation• Electrodes are implanted into one of three areasof the brain -- the globus pallidus, thethalamus, ...
Deep brain stimulation
Can we prevent PD?• Various researchers have beentrying to prevent PD or haltprogression of disease, but it is toosoon to ...
The Role of Environmental Toxins• Exposure to pesticidesand herbicides mayincrease the risk of PD• There may be geneticsus...
Parkinsons and Exercise• Exercise may actually have aprotective effect byenabling the brain to usedopamine more effectivel...
Living With PDParkinsons affects many aspects of daily life, butwith medications and supportive therapiespatient can remai...
Caregivers most important person• In addition to loosing motor skills PD patients areemotionally low. Depression often pre...
OPD Appointment Helpline: 022-39818181/67668181/24451515VOPS Schedule: Every Wednesday - 1300 to 1400 hoursOnline Appointm...
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Webinar on Parkinson’s Disease by Hinduja Hospital

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Hinduja hospital conducts regular webinars and tweetinars for online users where they can seek advice from expert doctors of hinduja hospital for free. Above is the webinar conducted by hinduja hospital on Parkinsons Disease where issues like parkinson disease, parkinson disease cure,parkinson disease symptoms,parkinson treatment were discussed successfully by Consultant Neurophysician, Dr. Charulata Sankhla.
To know more about such upcoming webinars and tweetinars from hinduja hospital, visit http://www.hindujahospital.com/communityportal/

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Webinar on Parkinson’s Disease by Hinduja Hospital

  1. 1. Things you want to know aboutParkinsons DiseaseDr. Charulata SankhlaConsultant NeurophysicianHinduja Hospital, Mumbai
  2. 2. What Is Parkinsons Disease (PD)?• A brain disorder that causes agradual loss of muscle control• Symptoms of PD tend to bemild initially and cansometimes be unnoticed.• Typical signs includetremors, stiffness, slowedbody movements, and poorbalance. Parkinsons wasoriginally called a "shakingpalsy," but not everyone withParkinsons has a tremor
  3. 3. James Parkinson 1817“Involuntary tremulousmotion, with lessenedmuscular power, in partnot in action and evenwhen supported; with apropensity to bend thetrunk forward, and topass from a walking to arunning pace: thesenses and intellectbeing uninjured”
  4. 4. Progression of the disease• While Parkinsons can be afrightening diagnosis, life expectancydoes not change particularly withbetter care. and prompt treatment• symptoms progress slowly over 10 to20years• Early treatment can allow patients tolive a normal life , maintain their job• We see young patients with PD inIndia as compared to west• Two advocates for researchdevelopment in PD: BoxerMuhammad Ali at age 42 and actorMichael J. Fox at age 30
  5. 5. Early Signs of this diseaseIt may be subtle and can be confused with otherconditions. They include:• Mild shaking of a finger, hand, leg, or lip• Frozen shoulder• Stiffness or difficulty walking• Difficulty getting out of a chair• Small, crowded handwriting• Stooped posture• A masked face, lack of expression
  6. 6. Tremor• It is an early symptom and isseen in about 70% of patients• Usually occurs in a finger orhand when the hand is at restwhen patient is walking orwatching TV- but not when thehand is in use• Hands and fingers shake as ifrolling a pill between thethumb and index finger
  7. 7. Bradykinesia• As we grow older, we slow down. bradykinesia inPD patients mean slow movement which impairsdaily activities• They tend to take small steps. They may suddenlystop particularly near doors or in crowded places.Their body does not respond to commands rightaway• The PD patients blink less and have mask like faceand have a soft voice or slurred speech
  8. 8. Impaired Balance• These patients have difficulty in turning swiftly• They tend to develop a stooped posture, withdrooping shoulders and their head jutted forward• They may have a problem with balance. Thisincreases the risk of falling• They tend to run in small steps forward
  9. 9. Rigidity• Rigidity means stiff muscles which dont relax• It is difficult to move patients arms and legspassively , there is some resistance• Due to rigidity the arms may not swing when aperson is walking• There may be cramping or pain in the muscles
  10. 10. Non motor symptoms• Night terrors, Restless sleep• Daytime fatigue• Constipation• Increase tendency to pass urine particularly innight• Difficulty swallowing• Memory problems, confusion, or dementia• Oily skin and dandruff
  11. 11. Can I get PD?• The average age of onset is 55 as one gets olderthe chances increase• Having a family member with PD slightlyincreases the risk• Men are more likely to have Parkinsons thanwomen
  12. 12. What happens in Brain?• A small area in the brain stem called thesubstantia nigra produces dopamine, a chemicalthat controls movements, their speed, planning• In PD these dopamine-producing cells die;• Resulting in the misplanning and altered speed ofthe movement. Also there is difficulty ininitiating movements
  13. 13. DAT SCAN
  14. 14. Various strategies in treatment of PD• Multidisciplinary approach• Medical• Surgery• Physiotherapy• Occupational therapy to modify home• Support group to increase awareness• Speech therapy
  15. 15. Drugs in PD• Levodopa preparations.• Dopamine receptor agonists.• Monoamine oxidase-B inhibitors.• Catechol-o-methyltransferase inhibitors.• Anticholinergics.• Amantadine
  16. 16. Deep Brain Stimulation• Electrodes are implanted into one of three areasof the brain -- the globus pallidus, thethalamus, or the subthalamic nucleus -- on one orboth sides. A pulse generator goes in the chest.• Electric pulses stimulate the brain to reduce apatients rigidity, tremors, and bradykinesia.• It doesn’t stop the progression of PD or affectother symptoms. Not everyone is a goodcandidate for this surgery. Selection of a properpatient is essential for good outcomepostoperatively
  17. 17. Deep brain stimulation
  18. 18. Can we prevent PD?• Various researchers have beentrying to prevent PD or haltprogression of disease, but it is toosoon to tell whether this works• Well water drinking in early agehave been found to increase thechances of developing the disease• Coffee drinkers and smokers mayhave a lower risk of developingParkinsons (although smokingobviously has other serious healthconsequences)
  19. 19. The Role of Environmental Toxins• Exposure to pesticidesand herbicides mayincrease the risk of PD• There may be geneticsusceptibility toenvironmental exposures• Workers exposed tomanganese in mines inIndia developedparkinsonian features
  20. 20. Parkinsons and Exercise• Exercise may actually have aprotective effect byenabling the brain to usedopamine more effectively.It also helps improve motorcoordination, balance, gait,and tremor. It releasesnerve growth factor whichmay play key role in PDbrains. Working out on atreadmill or biking havebeen shown to have abenefit. Tai chi and yogamay help with balance andflexibility.
  21. 21. Living With PDParkinsons affects many aspects of daily life, butwith medications and supportive therapiespatient can remain active. Medication can helppatients cope with mood disorders, such asdepression and anxiety. An occupationaltherapist can provide a home safety evaluationsuch as to remove fall hazards, throw rugs orcords, and add grab bars in the bathroom. Aspeech therapist can help with swallowing andspeech problems.
  22. 22. Caregivers most important person• In addition to loosing motor skills PD patients areemotionally low. Depression often precedes motorslowness.• To do daily tasks are marathon efforts for PD patients andthey should be constantly encouraged to do simple tasksindependently• Caregivers need to understand this and provide necessarysupport to keep patient active and independent• Support groups and online forums are available
  23. 23. OPD Appointment Helpline: 022-39818181/67668181/24451515VOPS Schedule: Every Wednesday - 1300 to 1400 hoursOnline Appointment: http://www.hindujahospital.com/vops/Visit us on: http://www.hindujahospital.com/dr-charulata-sankhla/For any Queries, please write us on: info@hindujahospital.comThank You!

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