Blood indices

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Blood indices

  1. 1. Mr. Govardhan Joshi
  2. 2. Introduction • Purpose of determining blood indices is to correlate the fundamental result obtained in CBC • Also useful to classify anemia
  3. 3. MEAN CORPUSCULAR HEMOGLOBIN • It is defined as the amount of hemoglobin in average red cell Or Average amount of Hb in all the red cell • It is directly proportional to the amount of hemoglobin and the size of the erythrocyte • Normal range = 27-32pg • 1pg=
  4. 4. Formula
  5. 5. Interpretation of MCH values • Low MCH values: are found in microcytic hypochromic anaemias and also when red cells are microcytic and normochromic. In thalassaemia minor the MCH is low even when anaemia is mild (MCHC is often normal) • Raised MCH values: found in macrocytic normochromic anaemia
  6. 6. Mean Corpuscular Volume (MCV) • It is defined as the average volume of red cell • It Provides information on red cell size • It is measured in femtolitres. • Normal range= 87±5fl • 1fL= L
  7. 7. Formula
  8. 8. Interpretation of MCV values • Low MCV values: are found in microcytic anaemias particularly iron deficiency, anaemia of chronic disease and thalassaemia • Raised MCV values: are found in macrocytic anaemias, marked reticulocytosis, and chronic alcoholism
  9. 9. MEAN CORPUSCULAR HEMOGLOBIN CONCENTRATION (MCHC) • The MCHC expresses the average concentration of hemoglobin per unit volume of erythrocytes. • It is expressed in percentage. • Normal value= 32-36%
  10. 10. Basic formula or
  11. 11. Interpretation of MCHC values • Low MCHC values are found in iron deficiency anemia and other conditions in which the red cells are microcytic and hypochromic. • An increased MCHC can occur in marked spherocytosis.
  12. 12. Summary of red cell indices in common anaemias Anemia MCV MCH MCHC Normocytic normochromic N N N Microcytic hypochromic D D D Macrocytic normochromic I I N

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