Discovery of novel cosmeceuticals (cosmetic products that have medicinal or
drug-like benefits) and nutraceuticals (dietar...
THE NEXT INGREDIENT IN ANTI-AGING SKIN CARE
Chemical peels
Exfoliants
CoQ10
Niacinamide
Peptides (EGF)
Retinol
Sunscreen
i...
GENETIKSIGNAL ANTI-AGING INNOVATION
DIETARY/
CALORIC
RESTRICTION
mTORC1
MITOCHONDRIA
Free radicals
ANTIOXIDANTS
Aging
Enzy...
Aging can be slowed: Dietary restriction
0
0.2
0.4
0.6
0.8
1
0 20 40 60 80
Age (Cell Divisions)
FractionViable
10 20 30 40...
VALUE PROPOSITION
Exclusive
license for IP;
methods U. S.
patents
Chemo
Preventative
Non-
carcinogen
No FDA
approval for
c...
MARKET OPPORTUNITY
Cosmeceuticals, Nutraceuticals
* Technology Insight Report – Antiaging skin care compositions –Patent I...
BUSINESS MODEL
Distributed partnering model
(Kauffman foundation)
Product
Definition
Company
Discovery
Definition
Developm...
BUSINESS STRATEGY
YEAR 1
• COMPOUND
IDENTIFICATION
• IN VITRO ANTI-
AGING YEAST
SCREENS
YEAR 2
• MAMMALIAN/
SKIN
FIBROBLAS...
MANAGEMENT TALENT:
CSO/CEO: GINA DEVASAHAYAM, BIOENTREPRENEUR
VP-CHEMISTRY: RYAN VAN DE WATER, MEDICINAL CHEMIST
SCIENTIFI...
THANK YOU!
www.genetiksignal.com
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  • Naturally derived next gen antioxidants, issued US patent
  • Genetiksignal_crowdfund

    1. 1. Discovery of novel cosmeceuticals (cosmetic products that have medicinal or drug-like benefits) and nutraceuticals (dietary supplement or food ingredient) by innovative anti-aging methods for healthy aging in skincare and nutrition
    2. 2. THE NEXT INGREDIENT IN ANTI-AGING SKIN CARE Chemical peels Exfoliants CoQ10 Niacinamide Peptides (EGF) Retinol Sunscreen ingredients Botox Hyaluronic acid Probiotics Microalgal Resveratrol Stem cells Anti-aging Skincare Compositions ingredients “cosmeceutical” refers to cosmetic products that have medicinal or drug-like benefits
    3. 3. GENETIKSIGNAL ANTI-AGING INNOVATION DIETARY/ CALORIC RESTRICTION mTORC1 MITOCHONDRIA Free radicals ANTIOXIDANTS Aging Enzymes (collagen, elastin) mRNA TRANSLATION AUTOPHAGY
    4. 4. Aging can be slowed: Dietary restriction 0 0.2 0.4 0.6 0.8 1 0 20 40 60 80 Age (Cell Divisions) FractionViable 10 20 30 40 Age (days) 0 0.2 0.4 0.6 0.8 1 0 FractionViable Control DR Control DR DR DR Control Control DR in yeast accomplished by decreasing glucose concentration from 2% to 0.5% or lower
    5. 5. VALUE PROPOSITION Exclusive license for IP; methods U. S. patents Chemo Preventative Non- carcinogen No FDA approval for cosmeceutical Low cost of starting compounds modulaTOR discovery portfolio Naturally derived next gen antioxidants
    6. 6. MARKET OPPORTUNITY Cosmeceuticals, Nutraceuticals * Technology Insight Report – Antiaging skin care compositions –Patent InSight Pro (2010) Cosmeceuticals –US industry study with forecasts for 2015 & 2020 by Freedonia Group, July 2011 Anti-aging • Global market for anti-aging products (which includes pharmaceutical products for age related health issues, supplements and appearance based products which include skin care) is an estimated $291.9 billion by the year 2015 * -100 0 100 200 300 400 $millions Vitamin A Vitamin E Vitamin C CoQ10 $700 million cosmeceutical skin care antioxidant market by 2017
    7. 7. BUSINESS MODEL Distributed partnering model (Kauffman foundation) Product Definition Company Discovery Definition Development Delivery IN-LICENSING OUT-LICENSING
    8. 8. BUSINESS STRATEGY YEAR 1 • COMPOUND IDENTIFICATION • IN VITRO ANTI- AGING YEAST SCREENS YEAR 2 • MAMMALIAN/ SKIN FIBROBLAST IN VITRO SCREENS • CRO • MARKETING YEAR 3 • PRODUCTION • MANUFACTURING • FORMULATION AND DELIVERY VALUE INFLECTION “COSMECEUTICAL DISCOVERY” SERIES A ROUND VALUE CREATION REVENUE (CUSTOMER) ROI IS 5-10X Strategic Alliances/ Partners: Cosmetics companies (Cosmeceuticals) Pharma consumer health companies (Nutraceuticals)
    9. 9. MANAGEMENT TALENT: CSO/CEO: GINA DEVASAHAYAM, BIOENTREPRENEUR VP-CHEMISTRY: RYAN VAN DE WATER, MEDICINAL CHEMIST SCIENTIFIC ADVISORY BOARD: MATT KAEBERLEIN, ASSOCIATE PROFESSOR FRANCIS BURROWS, CSO, AARDEN PHARMA LEGAL COUNSEL: CHARLES KATZ, EMERGING COMPANY & VC PRACTICE, MORRISON & FOERSTER BUSINESS ADVICE AND CONSULTING: INNOVATE PROGRAM (JHU, UMBC, MARYLAND) PROPRIETARY INTELLECTUAL ASSET: IP FROM UNIVERSITY OF WASHINGTON, SEATTLE
    10. 10. THANK YOU! www.genetiksignal.com
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