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Open app challenge_-_phase_1_submission_genelex_final
Open app challenge_-_phase_1_submission_genelex_final
Open app challenge_-_phase_1_submission_genelex_final
Open app challenge_-_phase_1_submission_genelex_final
Open app challenge_-_phase_1_submission_genelex_final
Open app challenge_-_phase_1_submission_genelex_final
Open app challenge_-_phase_1_submission_genelex_final
Open app challenge_-_phase_1_submission_genelex_final
Open app challenge_-_phase_1_submission_genelex_final
Open app challenge_-_phase_1_submission_genelex_final
Open app challenge_-_phase_1_submission_genelex_final
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Open app challenge_-_phase_1_submission_genelex_final

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  • 1. YouScript Personalized Prescribing System from Genelex “Putting personalized medicine into practice”Kristine Ashcraft, COO, GenelexCopyright © 2011 Allscripts Healthcare Solutions, Inc. 1
  • 2. Solution Overview  YouScript® is the first and only clinical decision support tool that enables healthcare providers to consider cumulative multi-drug and gene interactions not covered by e-prescribing or EHR software interaction checking.  YouScript integration with Allscript EHRs enables providers to consider the pharmacogenetic risk associated with a patient’s drug regimen at the point of care and to predict and prevent adverse drug events. • Assesses each providers’ patients to highlight those at high-risk, indicate whether pharmacogenetic testing is suggested, and offer risk management options. • Once tested, the patient’s Personalized Prescribing Report and genotype will be added to the patient’s profile. • Continues to monitor changes to the provider’s patient set, alerting the provider to new risks, and reflecting the total interaction risk for the provider’s patient population.  YouScript helps reduce the practice’s overall ADE risk level and contributes to better outcomes.  YouScript is the first real step towards putting personalized medicine into practice.A Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc. 2
  • 3. Solution Overview  Healthcare/Business problem addressed: • Adverse drug events are the third leading cause of death in the U.S. and cost the nation $289 billion in unnecessary healthcare costs. • More than 75% of the population have genetic variations that change how they react to the majority of commonly prescribed medicines. • YouScript helps reduce adverse drug events by ensuring every patient receives the right medication for their unique genotype in the context of their current medication regimen. Ultimately, this helps physicians improve patient outcomes and satisfaction, reduce ER visits and hospitalizations, and save time in medication selection.  The application developed addresses the following category:  Applications that improve management of high cost chronic diseases.  Innovative approaches to addressing value-based care imperatives.  BothA Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc. 3
  • 4. Usability and Design  YouScript leverages the tasking feature of Allscripts EHRs to prompt the provider to review high- risk patients on their schedule and consider pharmacogenetic testing when appropriate.  Once tested, YouScript adds actionable alerts to the Provider’s task list requiring them to review and approve the patient’s personal prescribing report.  YouScript aligns with the Allscript’s physician’s daily workflow by monitoring patient records for medication changes and prompting the provider to take action whenever a patient is placed at significant risk.  YouScript’s actionable Interaction Reports allow the physician to explore implications of possible medication changes, and identify the safest alternatives for the patient prior to prescribing.  YouScript empowers the provider to manage their practice’s overall risk level by providing dashboard views summarizing total population risk, and making concrete recommendations for next steps.A Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc. 4
  • 5. YouScript/Allscripts Workflow One Time 1 Test High 2 3 Review Test PGX Risk 4 Results Adjust Identify High Patients Risk Patients Medication Drug Risk Review Regimen Only YouScript Ongoing 5 6 7 Monitor Alert Provider Drug Change Change if Significant ImpactA Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc.
  • 6. Development Stage Please indicate the development stage as of the Phase 1 Submission Date:  Idea  Prototype  Code development in progress  Code complete  Code complete, tested and approved by Allscripts. • UI design and development is complete. Allscripts integration development is 50% complete with code complete targeted at end of March for a May release date.A Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc. 6
  • 7. Integration Description Current implementation based on available Allscripts APIs include: • Patient Demographic Data for the provider to view through YouScript. • Patient Medication Lists are extracted into YouScript. • YouScript inserts tasks into the provider task list • YouScript inserts new documents as a lab result and attaches them to a task. • YouScript updates patient record with genotype test results Proposed additional features requiring new Allscripts APIs: • Real-time alert of ADE risk increases when medication changes are madeA Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc. 7
  • 8. Integration Description APIs/Web Services calls include: • GetPatient • GetPatientSections • GetSchedule • SearchPatient • SaveDocumentImage • SaveProblemsData • SaveTask • SearchMedsA Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc. 8
  • 9. Go to Market Plans Provide information on business plans, including: • Genelex national sales team will coordinate with Allscripts field sales teams to leverage existing customer relationships and new prospects • Genelex will work with Allscripts to provide Webinar’s and seminars to educate Allscripts customers about the solution. • YouScript will be offered to Allscripts customers on a per user basis as an add- on service. • A 30-day free trial version will be available at Allscripts discretion. • Allscripts will receive a percentage of all per user fees. • Allscripts will receive a percentage of revenue for all tests generated through the ordering process. This is a significant revenue opportunity. • Initial target will be ambulatory physicians with particular emphasis on primary care, cardiology, pain, and psychiatry. • Targeting will expand to Hospitals and Medical Centers in stage 2.A Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc. 9
  • 10. Video Demonstration Video link: http://youtu.be/uDutOUdr2vY Description of what the demo shows • The demo shows the integration points between Allscripts and YouScript with a brief overview of how physicians can use YouScript to identify harmful interactions, prevent possible adverse drug events and lower their practice’s adverse drug event risk.A Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc. 10
  • 11. Why this solution should be selected! Despite widespread use of drug interaction software, one person dies every 5 minutes from “properly” prescribed drugs. Current drug interaction software is only capable of predicting binary drug- drug interactions, overlooking over one-third of significant risks. YouScript is the only software available to predict drug-gene, multi-drug and cumulative interaction risks - and offer safer alternatives, making it the first real step towards putting personalized medicine into practice. Updated bi-weekly, the YouScript database and algorithm is the most comprehensive resource and predictor of possible interactions, encompassing: • Over 2500 drugs & metabolites • Herbals, Over-the-counters, foods, and patient factors • Over 14,000 PubMed links & notes curated by medical experts Empowering physicians with pharmacogenetic insights at the point of care helps physicians provide better care and improves patient outcomes.A Connected Community of Health | Copyright © 2011 Allscripts Healthcare Solutions, Inc. 11

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