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The Global Leptospirosis Environmental Action Network: strengthening the public health prevention and outbreak control strategy
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The Global Leptospirosis Environmental Action Network: strengthening the public health prevention and outbreak control strategy

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Eric BERTHERAT1, Michel JANCLOES2, Emily FIRTH1, Kara DURSKI1 …

Eric BERTHERAT1, Michel JANCLOES2, Emily FIRTH1, Kara DURSKI1

1WHO, Switzerland; 2Health and Climate Foundation


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  • Expérience du réseau MERIT(Meningitis environment risk Information Technologies)
  • Transcript

    • 1. LEPTOSPIROSIS:Strengthening the public health prevention and outbreak control strategy Michel Jancloes MD, MPH, PHD Health and Climate Foundation 4th International Disaster and Risk Conference Davos 2012
    • 2. GlobalLeptospirosisEnvironmentalActionNetwork An intersectoral initiative ERIC BERTHERAT, MD, MPH, MSc GLEAN COORDINATOR Pandemic and Epidemic Disease WHO Geneva Health and Climate Global risk Forum Davos 28 08 2012 Foundation
    • 3. LEPTOSPIROSIS: Magnitude• A global endemic +epidemic disease• Of increasing magnitude through severe post-disaster outbreaks• Counting annually worldwide, – 557,000 cases – 55,8000 deaths• Estimated, when adjusted(LERG OMS) forpotential underreporting to cause annually – 1,730,000 cases, – 123,000 deaths• http://www.who.int/zoonoses/diseases/lerg/en/ Global risk Forum Davos 28 08 2012
    • 4. A Public Health Threat• A Major, – yet neglected, – non-detected, – under-reported disease• Absence of control strategy due to – Nonspecific symptoms – Complex transmission – Complex pathogen agent with multiple variants (>250 sero-variants)• Economic Impact: an important zoonosis• Probable impact of climate change• Increasing concerns at country level and request for technical support Global risk Forum Davos 28 08 2012
    • 5. Philippines, 2009 680 cases of leptospirosis /yr with seasonal peak during the rainy seasonTyphoonPepeng:3 OctoberTyphoon Ondoy:26 SeptemberThousands of people displaced and In the 2 following weeks, 505 suspecthoused in emergency evacuation ! cases and 15 deaths in Manila alonecenters Global risk Forum Davos 28 08 2012
    • 6. The Global Leptospirosis Environmental Action Network GLEAN:GLEAN: A response to a multidisciplinary and inter-sectorialchallenge for clinicians, public health, water and sanitationspecialists, veterinarians, climatologists, biologists, statisticians,anthropologists, economists. Global risk Forum Davos 28 08 2012
    • 7. GLEAN DevelopmentTo reduce the impact of post disaster outbreaks:1. Inventory of scientific evidence-state of the arts: Marseille 7-8 February 20112. Identification of knowledge and capacity gaps ISPRA 17—19 January 2012 Detection and confirmation: Case management Vaccination Mass chemoprophylaxis Rodent control Decontamination Environment Global risk Forum Davos 28 08 2012
    • 8. GLEAN Objectives 5 years strategic plan PREDICT PREVENT DETECT INTERVENEBaseline Incidence? Case definition? Operational Effectiveness of preventive Guidance forMain drivers and measures? outbreak control predictive Laboratory case value? Role of vectors? confirmation? Outbreak preparednessInforming public Role of human Algorithms for health decision? and animal outbreak vaccination ? detection ?Tools to validate at risk sites? Global risk Forum Davos 28 08 2012
    • 9. Global risk Forum Davos 28 08 2012
    • 10. Plan 2012• Preliminary recommendations for the control of human leptospirosis in post disasters situations .• Informing and mobilizing new partnership – Literature review (Minnesota University) – World mapping of the leptospirosis (endemic and epidemics) (WHO Washington) – Economic impact studies.• Laboratory consortium development• Rapid tests document (KIT Amsterdam et Pasteur Institut Paris) Global risk Forum Davos 28 08 2012
    • 11. Operational Recommendations summaryBased on current scientific evidence based data, the following may be recommended1. Systematic detection and empirical treatment of probable cases2. Collection and sending in number of laboratory samples of suspected cases to the laboratories of reference(confirmation and identification of pathogenic agents3. Protection of individuals at risk by port of protection devices4. Chemo prophylaxis of individuals at high risk5. Mass information.(integrated health education)In post-catastrophe phases, there is currently no evidence of impact of:1. Mass Vaccination: (human and animal)2. Mass chemo prophylaxis nor disinfecting waters : these measures are limited to for high-risk workers.3. Control of rodents out of context epidemic-(late intervention without on human transmission) Global risk Forum Davos 28 08 2012
    • 12. Health and ClimateTHANKS! (photos thanks to SABY) Foundation Global risk Forum Davos 28 08 2012

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