Computer Aided Detection-Exploring New Realms of Clinical Applications


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Research associate, Kaavya Karunanithi, explores computer aided detection within the healthcare industry.

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Computer Aided Detection-Exploring New Realms of Clinical Applications

  1. 1. Computer Aided Detection – Exploring New Realms of Clinical Applications Kaavya Karunanithi, Research Associate Healthcare September 8, 2011
  2. 2. Today’s Presenter: Kaavya Karunanithi Functional Expertise •Market research in the Medical Imaging sector •Competitive analysis and benchmarking skills •3 years of research experience in various sectors of biotechnology, biomedical and biomaterials engineering Implementation of Strategies Industry Expertise •Knowledge of various Medical Imaging and devices sectors in the European market •Authored various market insights and research services in the medical imaging sector What I bring to the team •Novel outlook at the market perspectives Evaluation of •Technical expertise and skilled analytics Opportunities & StrategiesKAAVYA KARUNANITHIResearch Associate- Career highlightsHealthcare •Co-authored articles in international peer reviewed journals •Worked on cloning and characterization of BCAS and OCIAD genes in Indian Institute of ScienceFrost & Sullivan, Europe •Worked on cloning and characterization of HCN 4 genes at Dr KM Cherian tissue engineeringChennai, India institute •Worked on design and optimization of coils for cerebral aneurysms using computational fluid dynamics principles at Australian School of Advanced medicine Generation of •Member of Association of Professional Engineers, Scientists and Managers, Australia (APESMA) Opportunities & Strategies Education •Masters in Biomedical engineering, University of Sydney, Sydney, Australia •Bachelor of Biotechnology, SRM university, India •Business English Communication (Cambridge University)- certified 2
  3. 3. Focus Points Market overview Supply chain analysis Industry challenges Market drivers and restraints Market forecasts Geographic trends Competitive analysis Strategic recommendations 3
  4. 4. Market Overview •CAD has long since left behind its branding as a supplement tool and has now widened its application areas. It is now a valuable tool for detection and diagnosis of various types of cancer. This European CAD market is in its early growth stageCAD software constitutes a set of algorithms, which and is highly dependent on its corresponding imagingby using the technique of pattern recognition, aides modality market dynamics for its market penetration.the radiologist in detecting potentially diseased With increasing use of CAD software for variousregions and lesions. This is done by using clinical diagnostic applications of oncology, the market can beimages obtained from various imaging modalities as described as highly specialized, competitive anda platform. dynamic with considerable growth potential. A unique feature of CAD market is the OEMs that incorporate CAD solutions into their modalities have a huge role to play in determining the market dynamic parameters, along with CAD suppliers. 4
  5. 5. Market ScopeProduct segmentation Geographic scope CAD United Kingdom Germany Breast CAD Chest CAD Benelux France Colon CAD Prostate CAD Scandinavia Spain Liver CAD Italy Bone CAD 5
  6. 6. Technology and Market Trends• The European CAD market will have increasing growth rates as the need for digitization and highly automated RIS integrated workflow will increase with widening clinical Demographic reports applications of CAD and development of multimodal imaging solutions.• The commercialization of investigational CAD Imaging applications will lead to new entries in the market Modality thereby expanding the product portfolio available in terms of technologically superior variants such as Medic sights colon CAD 4.0. The increased competition may CAD also result in price fluctuation.• There is a need for large scale clinical studies validating the competence of CAD products. This will aid in its Diagnostic Image Imaging Storage widespread penetration throughout Europe. workstation• The market is expected to grow steadily during the forecast period. Newer segments like chest, colon, Online Off line Data Image recovery prostate, liver and bone will have an increased percent storage back up revenue contribution to the total CAD market of Europe. Source: Frost & Sullivan 6
  7. 7. Market Adoption Trends •From the graphical representation we 3.5 can see that there has been a steady rise 3.0 in the number of cancer incidences 2.5 reported for the past 5 years. 2.0 1.5 •Germany, France, Spain and Italy has 1.0 the highest compound annual growth 0.5 rate of cancer occurrence. 0.0 United Scandina •Breast, prostrate and colon cancer Germany France Spain Italy Benelux Kingdom via along with coronary artery disease acts 1.3 1.6 2.9 2.6 3.3 0.1 1.6 CAGR of cancer incidence for 2005-2010 in % as the single largest cause of death in Europe according to the report published by European Union. Compound annual growth rate of reported cancer •This has in turn increased the need for incidences (Europe), 2005-2010 early detection of the mentioned conditions by using various prognostic/diagnostic measures like CT, MRI and US scans, which incorporate CAD modality within them.Source: Frost & Sullivan 7
  8. 8. Healthcare Expenditure Overview - Europe 60,000.0 Benelux •A number of large scale multi Scandinavia 50,000.0 centric clinical trials are being held Italy for validating the efficiency of 40,000.0 France established CAD regimes namely, Germany 30,000.0 United Kingdom breast and colon CAD. Spain 20,000.0 •The results of these studies indicate a 15 to 40 percent 10,000.0 reduction in the cancer mortality 0.0 rate. 0.0 1,000.0 2,000.0 3,000.0 4,000.0 5,000.0 6,000.0 •Additional short term clinical H e a lt hc a re e xpe ndit ure pe r c a pit a $ studies on newer clinicalSource: Frost & Sullivan applications of CAD including Due to increased prevalence of cancer, European bone, prostate and liver offer countries have and are continuously increasing their promising results which imply percent GDP spent on cancer prevention and CAD as a robust diagnostic tool in regulation. the early detection of cancer. This is evident from the healthcare expenditure per capita data given above. 8
  9. 9. Geographic Trends• Numerous nationwide screening programs for detection of breast cancer using digital mammography techniques which incorporate CAD along with colon cancer screening programs are already in place in most of the European countries like the United Kingdom, Germany, France etc.• NHS has recently introduced an informed choice, Prostate cancer risk management program based on the results of the European Randomized Screening for Prostate Cancer (ERSPC) study.• Informed choice programs for low dose helical CT scanning for lung cancer has been introduced in France and Benelux. 9
  10. 10. Supply Chain Analysis•The supply chain for the CAD industry in Europe isversatile in nature.•There are absolute standalone workstations or CADintegrated with the imaging modality. A fair share of market CADparticipants have started offering web-based services of ManufacturerCAD solution.•CAD solutions of non Europe-based manufacturers is soldthrough regional distributors. Some of the CADmanufacturers like iCAD and EDDA technologies havestrategic alliances with the OEMs, which involve in selling Alliances Direct with OEMthe third party CAD software as a part of their imaging Distributors Sales/Web Manufactumodality. services rers•The larger OEMs like GE and Siemens also integrate their inhouse CAD algorithms into their CT and MRI scanner.•The newer trend of web-based services and pay-per-use End Usersmodel is gaining acceptance with the users as they get to (Hospitalshave a say in the customized payment model. and Clinics)•In future, we can expect an increased preference for thismode of distribution. At the end of forecast period, this shift ,will be evident. Nevertheless the standard procedure of salesthrough software distributors and integrated workstationswill also be practiced. Source: Frost & Sullivan 10
  11. 11. Industry Challenges Need for large-scale clinical studies validating the efficiency of CAD procedures Ambiguous reimbursement patterns affect the adoption rate of the technology Industry Challenges Dynamic market state, in terms of technology and competition, demands continuous evolution of its products Inhibition of radiologists against CAD utilization and shortage of resources and trained personnel 11
  12. 12. Market Drivers and Restraints Very High High Growth Growth Commercialization Impact Impact of investigational Increased prevalence and CAD areas awareness of cancer and coronary artery disease Growth and performance of CAD software manufacturers have greater dependence on larger OEMs Urgent need for a high number of white papers and publications High cost of solution validating efficiency and a highly competitive market Transition to Electronic Low induces price war Health Records (EHR) Medium Growth Growth Impact Impact DRIVER RESTRAINT Source: Frost & Sullivan 12
  13. 13. Product Lifecycle Analysis Innovators Early adopters Early majority Late majority Laggards Breast CADAdoption Chest CAD Colon CAD Prostate CAD Liver CAD Bone CAD Time Source: Frost & Sullivan 13
  14. 14. Market Parameters and Forecasts Number of 1. 0 0 . 5 % % Per cent revenue competitors 3.5% % 1. 6 contribution by segments (2010) 14 . 4 % 17+ Average price 79.0% per unit $50,000-Breast Chest Colon $150,000Prost rat e Liver Bone $822.7 M R&D Spend as a Percent of $234.8 M Market Revenue Marketing Spend as a Percent of 6% CAGR (2010-2017) 20.7% Market Revenue 4.5%2010 2017 Source: Frost & Sullivan 14
  15. 15. Competitive Analysis •SiemensTier 1 •Philips Competitive Factors •GE •iCAD -Product portfolio width -Geographic presence -Price •Medicsight -Business Model •Sectra - Vendor Relationship •Riverain medicalTier 2 & 3 •Medipattern •Median •EDDA •im3D •Confirm 15
  16. 16. Strategic Recommendations Widening the scope of clinical applications to all areas of oncology and cardiology is a key technological trend. Chest CAD solutions is likely to have exponential growth in the next 3-4 years. Prostate CAD will also be a high growth rate segment. Heavy marketing of bone CAD and slow growth of colon and liver CAD will be observed.CONCLUDING Mammo CAD is likely to reach a steady growth rate and will reach the pinnacle in terms of POINTS adoption, whereas breast MRI and ultrasound CAD is here to grow. Need for digitization and automated integrated workflow processes will act as major drivers for market. Large scale, long-term clinical studies and white papers will be needed to prove potency in CAD’s newer segments. Germany, UK and France are big markets for chest and prostate CAD. Scandinavia and Benelux will have a high adoption rate in terms of emerging segments of CAD; and Spain and Italy will continue to contribute to colon CAD’s revenue. Breast CAD will have a uniform penetration rate throughout Europe. 16
  17. 17. Next Steps Request a proposal for Growth Partnership Services or Growth Consulting Services to support you and your team to accelerate the growth of your company. ( Join us at our annual Growth, Innovation, and Leadership 2012: A Frost & Sullivan Global Congress on Corporate Growth occurring 15 – 16 May, 2012 ( Register for Frost & Sullivan’s Growth Opportunity Newsletter and keep abreast of innovative growth opportunities ( 17
  18. 18. Your Feedback is Important to Us What would you like to see from Frost & Sullivan?Growth Forecasts?Competitive Structure?Emerging Trends?Strategic Recommendations?Other? Please inform us by rating this presentation Frost & Sullivan’s Growth Consulting can assist with your growth strategies 18
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  20. 20. For Additional InformationKatja Feick Noel AndersonCorporate Communications European Vice PresidentHealthcare New Business Development0049 (0) 69 7703343 +44 (0)207 343 noel.anderson@frost.comKaavya KarunanithiResearch Associate - MedicalTechnologiesHealthcare+91 44 6160 20