Nocturnal enuresis is defined as the repeated involuntary discharge of urine during sleep after a child is developmentally expected to attain bladder control. It is diagnosed when a child voids twice a week for at least 3 months and experiences distress. Nocturnal enuresis is more common in boys than girls and affects around 15-20% of 5 year old children, with 90% experiencing the persistent type. Causes include genetic factors, physiological immaturity, psychological stress, and organic issues like urinary tract infections. Treatment begins with behavioral modifications like rewards, scheduled voiding, and alarms, with medication options if unsuccessful.