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View stunning SlideShares in full-screen with the new Android app!View stunning SlideShares in full-screen with the new iOS app!
Insulin Anabolic 51 amino acids pro- insulin – C peptide removed 2 polypeptide chains – disulphide bridges Beta cells Binds to alpha sub unit of insulin receptor Autophosphorylation of tyrosine kinase Activates protein kinases Gene on short arm of chromosome 11
Effects of Insulin Carbohydrate metabolism Glucose uptake – liver /skeletal muscle Glycogen storage Glucose utilisation as energy source
Effects of Insulin Protein metabolism Stimulates amino acid uptake by cells Stimulates protein synthesis Inhibits Gluconeogenesis