Leprosy - Part 1 - a presentation at www.eyenirvaan.com

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Leprosy - Part 1 - a presentation at www.eyenirvaan.com

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Leprosy - Part 1 - a presentation at www.eyenirvaan.com

  1. 1. Pradnya Gogate B. Optom, LEPROSY PART 1 To view more presentations and articles, visit www.eyenirvaan.com
  2. 2. LEPROSY Hansen’s disease Chronic, granulomatous  Etiology: Mycobacterium leprae  Male: Female ratio –2:1  Transmission in nasal discharge, contact  To view more presentations and articles, visit www.eyenirvaan.com
  3. 3. CLASSIFICATION  Tuberculoid  Lepromatous  Borderline/ Dimorphous To view more presentations and articles, visit www.eyenirvaan.com
  4. 4. TUBERCULOID  Benign  Distribution: Face, skin, gluteal region, limbs  Asymmetrical lesions, anhydrotic  Polyneuritis  Claw hand, foot drop  Nerves involved Eg. Ulnar, peroneal  Loss of sensation To view more presentations and articles, visit www.eyenirvaan.com
  5. 5. LEPROMATOUS Macular, diffuse nodular  Distribution: Face, ear lobes, neck, extremities, trunk  Borderline Intermediate between lepromatous & tuberculoid  Bizarre skin lesions (eyes, nose)  To view more presentations and articles, visit www.eyenirvaan.com
  6. 6. LEPRA REACTIONS Inflammation in pre-existing lesions  Type I: Borderline & tuberculoid  Mechanism: Cell mediated hypersensitivity  Occurs spontaneously, loss of nerve function, swollen skin lesions  Type II: Common in 2nd year of treatment  Fever, painful papules/nodules(erythema nodosum leprosum) To view more presentations and articles, visit www.eyenirvaan.com
  7. 7. OCULAR FEATURES Conjunctivitis  Keratitis  Loss of eyelash/ eyebrows  Scleritis  Corneal anaesthesia  Iritis (lepromatous)  Severe miosis, iris atrophy  To view more presentations and articles, visit www.eyenirvaan.com
  8. 8. LEPROMATOUS IRITIS To view more presentations and articles, visit www.eyenirvaan.com
  9. 9. INVESTIGATIONS  Slit skin smear: Lesions from ear lobe, ring/middle finger  Lepromin test (suspension of dead M.leprae) Classify disease, determine prognosis/treatment To view more presentations and articles, visit www.eyenirvaan.com
  10. 10. MANAGEMENT  Isolation of patient till non-infectious  Three drug therapy: Rifampicin Clofazimine 50mg/day Dapsone 2mg/kg/day  Chemotherapy for lepra reactions: Thalidomide 100mg/6hrs Aspirin 600mg/6hrs Steroids To view more presentations and articles, visit www.eyenirvaan.com
  11. 11. PREVENTION  Avoid contact  Regular treatment  Follow up  Improve socio-economic conditions To view more presentations and articles, visit www.eyenirvaan.com
  12. 12. THANK YOU CONTINUE TO PART II … To view more presentations and articles, visit www.eyenirvaan.com

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