• Share
  • Email
  • Embed
  • Like
  • Save
  • Private Content
Mood, Movement and Memory 2013
 

Mood, Movement and Memory 2013

on

  • 1,328 views

Learn how exercise can powerfully influence your risk of mood disorders and Alzheimer's disease.

Learn how exercise can powerfully influence your risk of mood disorders and Alzheimer's disease.

Statistics

Views

Total Views
1,328
Views on SlideShare
1,306
Embed Views
22

Actions

Likes
0
Downloads
0
Comments
0

2 Embeds 22

http://www.esserhealth.com 20
http://esserhealth.com 2

Accessibility

Upload Details

Uploaded via as Microsoft PowerPoint

Usage Rights

© All Rights Reserved

Report content

Flagged as inappropriate Flag as inappropriate
Flag as inappropriate

Select your reason for flagging this presentation as inappropriate.

Cancel
  • Full Name Full Name Comment goes here.
    Are you sure you want to
    Your message goes here
    Processing…
Post Comment
Edit your comment
  • http://i.i.com.com/cnwk.1d/i/tim2/2013/05/16/militarystock_620x350.jpg http://www.thegatewaypundit.com/wp-content/uploads/2012/12/adam-lanza.jpg Adam lanza
  • http://www.nimh.nih.gov/statistics/1anymooddis_adult.shtml Estimated $147 billion in costs
  • YLD’s years lived with disability
  • Sleep Interest Guilt Energy Concentration Appetite Psychomotor slowing Suicidailty
  • http://www.nature.com/ijo/journal/v27/n4/abs/0802204a.html http://www.psychosomaticmedicine.org/content/69/8/740.short
  • The Substance Abuse and Mental Health Services Administration ... OF 8million on disability, nearly 2million for “ mood disorder” 2 nd largest diagnostic cause for disability 2 nd to MSK disorders (ie: back pain etc)
  • Cogito ergo sum…………rene decartes challenges our sense of personhood…our sense of identity….
  • Cadaveric study on a woman with an unusual mental illness…..with memory loss, language problems and odd behavior….found some off things in the brain we will talk about..
  • Approx. 1,300,000 new cases per year www.cdc.gov/.../mmwrhtml/ figures/m846qsf.gif www.ncbi.nlm.nih.gov/ bookshelf/picrender.fcgi.. http://www.ctahr.hawaii.edu/CS/blogs/sustainable_agriculture/cdc_logo(2).jpg
  • http://www.alz.org/alzheimers_disease_facts_and_figures.asp
  • http://ladulab.anat.uic.edu/images/ADstain.jpg
  • Smoking: http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(97)07541-7/fulltext http://www.neurology.org/content/52/7/1408.short Obesity: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC558283/?rendertype=abstract Diabetes: http://aje.oxfordjournals.org/content/145/4/301.short http://aje.oxfordjournals.org/content/154/7/635.short Homocysteine http://www.sciencedirect.com/science/article/pii/S1474442203004381 http://www.alz.org/alzheimers_disease_causes_risk_factors.asp
  • --http://www.cdc.gov/nccdphp/publications/factsheets/Prevention/pdf/obesity.pdf --http://www.cdc.gov/nccdphp/publications/factsheets/Prevention/obesity.htm
  • http://www.heart.org/idc/groups/heart-public/@wcm/@sop/@smd/documents/downloadable/ucm_319587.pdf The prevalence of hypertension (defined as high blood pressure or taking antihypertensive medication) increases with age. In 2005–2008, 33%–34% of men and women 45–54 years of age had hypertension, compared with 67% of men and 80% of women 75 years of age and over (Table 67).
  • http://www.cdc.gov/nchs/data/databriefs/db92_fig1.png
  • In 2005-2008 11% of adults 20 years of age or older had diabetes. In 2005-2008 the percentage of adults with dm increased with age from 4% of persons 20-44 to 27% of adults 65 years of age or older http://meps.ahrq.gov/mepsweb/ Medical Expenditure Panel survey
  • http://www.cdc.gov/nchs/fastats/exercise.htm
  • http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654704/ 2003-2004 NHANS Data set…… National Health and Nutrition Examination Survey (NHANES)
  • Cholinesterase Inhibitors……….. Razadyne® (galantamine), Exelon® (rivastigmine), and Aricept® (donepezil). Another drug, Cognex® (tacrine) Namenda® (memantine), an N-methyl D-aspartate (NMDA) antagonistAmantadine,
  • Obesity inc by 78% Smoking inc by 200%..... Cognitive reserves…… Smoking: http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(97)07541-7/fulltext http://www.neurology.org/content/52/7/1408.short Obesity: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC558283/?rendertype=abstract Diabetes: http://aje.oxfordjournals.org/content/145/4/301.short http://aje.oxfordjournals.org/content/154/7/635.short http://www.alz.org/alzheimers_disease_causes_risk_factors.asp
  • What’s the best workout plan.com Hahashop.com
  • Smoking: http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(97)07541-7/fulltext http://www.neurology.org/content/52/7/1408.short Obesity: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC558283/?rendertype=abstract Diabetes: http://aje.oxfordjournals.org/content/145/4/301.short http://aje.oxfordjournals.org/content/154/7/635.short Homocysteine http://www.sciencedirect.com/science/article/pii/S1474442203004381 http://www.alz.org/alzheimers_disease_causes_risk_factors.asp
  • ( Journal of the American Medical Association JAMA: 2000, Vol. 283. No. 22, pp. 2961-2967) http://www.news.harvard.edu/gazette/1999/10.21/diabetes.html http://www.reuters.com/article/healthNews/idUSTRE53E71N20090415?feedType=RSS&feedName=healthNews http://www.nature.com/bjc/index.html http://www.ncbi.nlm.nih.gov/pubmed/18599492?ordinalpos=18&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
  • Increases the cognitive reserves…….
  • http://www.neurology.org/content/early/2012/04/18/WNL.0b013e3182535d35.abstract http://articles.latimes.com/2012/apr/18/news/la-heb-alzheimers-physical-activity-elderly-20120418 http://140.116.183.158:100/BFRC/upload/4f3666d911077-exercise_is_associated_with_reduced_risk_for_incident_dementia_among_persons_65_years_of_age_and_older.pdf http://archneur.jamanetwork.com/article.aspx?volume=58&issue=3&page=498
  • Exercise Program for Nursing Home Residents with Alzheimer’s Disease: A 1-Year Randomized, Controlled TrialJ Am Geriatr Soc 55:158–165, 2007.
  • Example…if you take up running for the first time…success should not be running a marathon in 2 hours……rather 15 minutes without running may be a legitimate goal etc
  • SpecificWell definedClear to anyone that has a basic knowledge of the project MeasurableKnow if the goal is obtainable and how far away completion is Know when it has been achievedAgreed UponAgreement with all the stakeholders what the goals should be RealisticWithin the availability of resources, knowledge and time Time BasedEnough time to achieve the goalNot too much time, which can affect project performance
  • I hope you moved one step down the path of change…from thinking to doing, or from doing to embracing….
  • Frequqncy: How often? Intensity……..start slowly…build up gradually…….

Mood, Movement and Memory 2013 Mood, Movement and Memory 2013 Presentation Transcript

  •   Movement, Mood and Memory:  Exploring connections, setting goals Stephan Esser MD www.esserhealth.com
  • Exercise? Fingers, Feet and ForksFingers, Feet and Forks
  • I want you to…… • Be familiar with basic mood disorders • Know what Alzheimer’s is • Understand the basics of Exercise • Prepare to apply the information to your  health
  • Mood Disorders • A group of mental disorders involving a  disturbance of mood, along with either a full  or partial excessively happy (manic) or  extremely sad (depressive) syndrome not  caused by any other physical or mental  disorder. Mood refers to a prolonged emotion • Depression • Bipolar: Cyclic lows and highs http://medical-dictionary.thefreedictionary.com/mood+disorder The mind is its own place, and in itself can make a Heav'n of Hell……a Hell of Heav'n. JOHN MILTON (1608-1674) The mind is its own place, and in itself can make a Heav'n of Hell……a Hell of Heav'n. JOHN MILTON (1608-1674)
  • Mood Disorders
  • Depression • Epidemiology:  – about 121 million people worldwide. – NIMH: In any given 1-year period, 9.5 percent of the population, or about 20.9  million American adults, suffer from a depressive illness – 1 in 10 Adults • Cost of Care: – leading cause of disability as measured by YLDs  – By 2020, depression is projected to reach 2nd place in the ranking of DALYs  calculated for all ages, both sexes with more spending then on CV disease. – Workplace: annual workplace cost of depression in America      at over $40 billion – Personal:  Incalculable • Associated Factors: -ass. with 850,000 suicides/yr "Men are disturbed not by "Men are disturbed not by  things, but by the view things, but by the view  which they take of them.“which they take of them.“ EpicletusEpicletus -The Enchiridion--The Enchiridion- "Men are disturbed not by "Men are disturbed not by  things, but by the view things, but by the view  which they take of them.“which they take of them.“ EpicletusEpicletus -The Enchiridion--The Enchiridion-
  • Depression A: one of the criteria from category 1 and three of the  criteria from category 2 for most of the day nearly every  day for at least 2 weeks – Category 1: • Persistent depressed mood • Anhedonia – Category 2: • SIGECAPS B: symptoms do not meet criteria for mixed episode C: symptoms cause significant impairment D: symptoms not due to substance or GMC
  • Etiology • Combination: –Genetic –Environmental • Psychosocial • Neurophysiologic • Nutritional • Pharmacologic We can Nurture  Nature We can Nurture  Nature
  • Risk Factors • Gender: Women • Family:  • Marital Status:  Divorced, widowed,  separated • Social Class: Poverty • Life Events/Traumas • Medical Co-morbidities • Obesity • Gender: M=F • Family:    • Marital Status:  Divorced, widowed,  separated • Social Class: = Exercise, Nutrition, Sleep, Sunlight (Vitamin D Status), Metabolic DysfunctionExercise, Nutrition, Sleep, Sunlight (Vitamin D Status), Metabolic Dysfunction
  • What we know about  Mood Disorders • Common • Many Risk Factors: Multifactorial etiology • Expensive: $135 Billion SAMSHA 2012 • Debilitating • Complex • Prevention must be primary
  • TransitionTransition
  • Alzheimer’s The most common form of Dementia
  • Definitions • Dementia: – Latin roots: De (absence) ment-(mind) – loss of cognitive ability in a previously healthy  person, that is greater then what would be  expected from natural aging alone – Frequent Deficits: • Memory • Attention • Language • Problem solving
  • Dementia • Types: – Alzheimer’s – Vascular – Fronto-Temporal – Dementia with Lewy Bodies – Mixed – Other:  Metabolic, Vitamin Deficiency’s, Syphillis,  HIV, Medication s/e’s, dementia pugilistica etc
  • Alzheimer’s • 1906: Described by German psychiatrist Alois  Alzheimer MD • “Alzheimer’s disease is an irreversible,  progressive brain disease that slowly destroys  memory and thinking skills and, eventually  even the ability to carry out the simplest tasks  of daily living.”  National Institute of Aging, NIH 2012
  • Mortality Statistics
  • Statistics • 5.4 mill. Americans have Alzheimer’s • 1 in 8 adults over 65 y/o • Spending: – 300% higher Medicare costs if pt has dementia – Projected thru 2050 a 500% increase in combined Medicare and Medicaid spending
  • Cause ?
  • Outcomes Beta-amyloid plaquesBeta-amyloid plaques Neurofibrilary TanglesNeurofibrilary Tangles
  • Cause ?
  • Risk Factors Non-Modifiable • Age >65 – 5 yrs = double risk • Gender ? • Family History • Ethnicity • Genetics –  risk – Apo-E Modifiable • HBP/HLD/CAD • Homocysteine • Obesity 78% • Diabetes • Smoking 200% • Head Trauma • Exercise • Nutrition • Education
  • 2 of 32 of 3
  • The Problem • High Blood Pressure: – 1 in 3 adults 1:3 adults1:3 adults
  • 1:6 adults1:6 adults
  • The Problem 1:9 adults1:9 adults
  • Exercise • Achieve recommended levels of Exercise: – 20% of all adults >20 y/o – 13% of those age 65-74 y/o – 6% of those >75 y/o
  • Nutrition Consume Recommended Servings of Fruits and Vegetables: -Adolescents: 0.9% -Men: 2.2% -Women: 3.5% Consume Recommended Servings of Fruits and Vegetables: -Adolescents: 0.9% -Men: 2.2% -Women: 3.5%
  • What we know • Basics of Alzheimer’s • Foundational Statistics • Risk Factors We “Ain’t doing so good”
  • Treatment • No Proven Universal Cure • Medications: – Delay institutionalization • Symptom Focused – Behavior, incontinence, depression • Environmental
  • To Maintain Mood and Memory Prevention is Essential
  • Risk Factors •Gender: Women •Family •Marital Status •Social Class •Events/Traumas •Medical Co-morbidities •Obesity
  • Exercise
  • Definitions • Exercise: –movement of the body resulting in the enhancement of health and improvement of function
  • Categories • Leisure time Exercise: organized sports, running, gym activities, rehabilitation etc. • Lifestyle Exercise: activity incorporated into our daily pattern of life – eg: parking in the distant portion of the parking lot rather then the first bumper, taking the stairs instead of the elevator, mowing your own lawn, sweeping the house etc.
  • Exercise • Flexibility: 2-3 x’s/wk • Balance: 2-3 x’s/wk • Strength: 2-3 days/wk • Cardiovascular: 150 min/wk
  • How could we hypothesize exercise might reduce Alzheimer’s risk?
  • Risk Factors Non-Modifiable • Age >65 – 5 yrs = double risk • Gender ? • Family History • Ethnicity • Genetics –  risk – Apo-E Modifiable • HBP/HLD/CAD • Homocysteine • Obesity 78% • Diabetes • Smoking 200% • Head Trauma • Exercise • Nutrition • Education
  • Benefits of Exercise •  risk of HBP/Hchol/CAD •  risk of Obesity •  risk of Type 2 Diabetes • Less likely to smoke • More likely to eat health promoting foods
  • Exercise and Physical Health • Reduces risk of – Heart Disease ≈ 40% – Obesity: ≈ 30-100% – Stroke ≈ 50% – Type 2 Diabetes ≈ 50% – Hypertension ≈ 50% – Disability delayed ≈15 years – Colon Cancer ≈ 25-40% – Breast Cancer ≈ 20%-44% – Osteoporosis ≈ 20+% • As many as 250,000 deaths per year in the United States areattributable to a lack of regular physical activity
  • Benefits of Exercise • Obvious physiologic benefits • Cognitive value • Multi-system – Cognitive, balance, coordination, strength, CV etc – Executive, purpose, intention, goal-setting etc
  • Exercise and Alzheimers • Delays the onset and reduces incidence • Those who are in the top 10% of exercisers have a 250% lower risk of alzheimers
  • “A simple exercise program, 1 hour twice a week, led to significantly slower decline in ADL score inpatients with AD living in a nursing home than routine medical care.” 2007 “A simple exercise program, 1 hour twice a week, led to significantly slower decline in ADL score inpatients with AD living in a nursing home than routine medical care.” 2007 Exercise training for depressed older adults with Alzheimer's disease 2008 “…with severe AD evidenced a clear benefit to participants in this study “ Exercise training for depressed older adults with Alzheimer's disease 2008 “…with severe AD evidenced a clear benefit to participants in this study “
  • Depression
  • Exercise and Depression • The Antidepressive Effects of Exercise CJSM 2009 – Meta Analysis of 58 randomized studies (n = 2982) – Participants in the exercise treatment had significantly lower depression scores – In many studies, similar outcomes to medication – Dropout rates for the exercise treatment were similar to those found in psychotherapeutic and drug interventions.
  • How could we hypothesize exercise might influence Depression?
  • How does it Work? • Psychology • Neurogenesis • Neuro-Biochemistry
  • Psychology • Exercise and clinical depression: examining two psychological mechanisms Psych. of Sport and Exercise 2005 – 2 Groups: Exercise vs Control – 9 wk program – Exercisers: • Dec. Depression Scores • Inc. Coping and Self Efficacy • Less Rumination • Less evidence that increased distraction was etiology
  • Neurogenesis • Antidepressant effects of exercise: Evidence for an adult-neurogenesis hypothesis? Journal of Psychiatry and Neuroscience 2006 – Exercise increases synthesis of new neurons in the adult brain – Up to 2-3 x’s growth in Hippocampus – Facilitates improved memory, completion of functional tasks, learning of new tasks/materials – Opposite effect seen with excessive stress
  • Neuro-Chemistry • Exercise results in increased production of – Norepinephrine – Serotonin – B-Endorphins
  • Transition
  • Stages of Change (Prochaska and DiClemente) 1: Pre-contemplation 2: Contemplation 3: Preparation/planning 4: Action 5: Maintenance 6: Permanent Maintenance (Termination)
  • My Reasons to Exercise • Feel good in my skin • Increase energy, Reduce stress • Increase my confidence, discipline • Be a role model, socialize, family time • It’s fun, I love to sweat and work hard • I love challenges • Reduce disease risk • Lower disability risk • Maintain independence Reduce my risk of Alzheimer’s and Depression Reduce my risk of Alzheimer’s and Depression
  • What are your reasons?
  • My Reasons NOT to Exercise • Time • I’m tired or lazy • Inconvenience (I forgot my clothes etc…) • Money (shoes, travel, racquets) • Other priorities • Hate Change • Don’t know what to do • I’m Injured
  • What are your reasons NOT to Exercise?
  • “Physical fitness can neither be achieved by wishful thinking nor outright purchase.” Joseph Pilates
  • You are never too old to set another goal or to dream a new dream C.S. Lewis
  • Defining Success • What is success for you? • Are such goals achievable, legitimate? • What will you do if you fail to “succeed”?
  • Setting Goals •Specific •Measureable •Achievable •Realistic •Timely
  • • “You have to work at living, period. You’ve got to train like you are training for an athletic event. Most older people just give up. They think, “I’m too old for that,” because they have an ache here or a pain there. Life is a pain in the butt; you’ve got to work at it.” - Jack LaLanne -
  • Establishing Priorities • Potential responsibilities, limitations • Discover balance • Be dynamic, flexible
  • If you have decided to start or increase your activity level…….now what?
  • FITT • Frequency • Intensity • Time • Type
  • Lasting Change • Track your efforts and progress • Re-visit your goals regularly • Adjust to meet your needs • Thrive!
  • “Eating alone will not keep a man well; he must also take exercise. For food and exercise…… work together to produce health.” Hippocrates Regimen 400 BC
  • “Exercise is just as essential as a rational diet” Dr. William Esser N.D. DC.
  • “First say to yourself what you would be; and then do what you have to do” Epictectus Greek Stoic Philosopher AD 55–AD 135
  • Thank You! Stephan Esser MD www.esserhealth.com