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european
resuscitation
council




                Summary
                of the main
                changes in the
                Resuscitation
                Guidelines
                ERC Guidelines 2010
2




                         European
                         Resuscitation
                         Council
    To p r e s e r v e h u m a n l i f e b y m a k i n g
    high quality resuscitation available to all
    The Network of National Resuscitation Councils




    Published by:
    European Resuscitation Council Secretariat vzw,
    Drie Eikenstraat 661 - BE 2650 Edegem - Belgium
    Website: www.erc.edu
    Email: info@erc.edu
    Tel: +32 3 826 93 21
    ©
      European Resuscitation Council 2010.
    All rights reserved. We encourage you to send this document to
    other persons as a whole in order to disseminate the ERC Guidelines.
    No part of this publication may be reproduced, stored in a retrieval
    system, or transmitted in any form or by any means, electronic,
    mechanical, photocopying, recording or otherwise for commercial
    purposes, without the prior written permission of the ERC.
    Version1.2
    Disclaimer: No responsibility is assumed by the authors and the
    publisher for any injury and/or damage to persons or property as
    a matter of products liability, negligence or otherwise, or from any
    use or operation of any methods, products, instructions or ideas
    contained in the material herein.
3


Summary of main changes since 2005 Guidelines

Basic life support                             improve the quality of CPR perform-
                                               ance and provide feedback to pro-
Changes in basic life support (BLS) since      fessional rescuers during debriefing
the 2005 guidelines include:
                                               sessions.

  ♦♦ Dispatchers should be trained to
  interrogate callers with strict protocols   Electrical therapies:
  to elicit information. This information     automated external defi-
  should focus on the recognition of          brillators, defibrillation,
  unresponsiveness and the quality of         cardioversion and pacing
  breathing. In combination with unre-
  sponsiveness, absence of breathing or       The most important changes in the 2010
  any abnormality of breathing should         ERC Guidelines for electrical therapies
  start a dispatch protocol for suspect-      include:
  ed cardiac arrest. The importance of
  gasping as sign of cardiac arrest is
  emphasised.                                  ♦♦ The importance of early, uninter-
                                               rupted chest compressions is empha-
                                               sised throughout these guidelines.
  ♦♦ All rescuers, trained or not, should
  provide chest compressions to victims
  of cardiac arrest. A strong empha-           ♦♦ Much greater emphasis on mini-
  sis on delivering high quality chest         mising the duration of the pre-shock
  compressions remains essential. The          and post-shock pauses; the continua-
  aim should be to push to a depth of          tion of compressions during charging
  at least 5 cm at a rate of at least 100      of the defibrillator is recommended.
  compressions min-1, to allow full chest
  recoil, and to minimise interruptions
  in chest compressions. Trained rescu-        ♦♦ Immediate resumption of chest
  ers should also provide ventilations         compressions following defibrillation
  with a compression–ventilation (CV)          is also emphasised; in combination
  ratio of 30:2. Telephone-guided chest        with continuation of compressions
  compression-only CPR is encouraged           during defibrillator charging, the
  for untrained rescuers.                      delivery of defibrillation should be
                                               achievable with an interruption in
                                               chest compressions of no more than 5
  ♦♦ The use of prompt/feedback devic-         seconds.
  es during CPR will enable immediate
  feedback to rescuers and is encour-
  aged. The data stored in rescue equip-       ♦♦ Safety of the rescuer remains par-
  ment can be used to monitor and              amount, but there is recognition in
4



    Adult Basic Life Support

            UNRESPONSIVE?




              Shout for help




              Open airway




       NOT BREATHING NORMALLY?




                Call 112*




          30 chest compressions




            2 rescue breaths
            30 compressions



      *or national emergency number
5



Automated External Defibrillation

                              Unresponsive?



                                                                      Call for help




                               Open airway
                          Not breathing normally

                                                                 Send or go for AED
                                                                     Call 112*

                                                                * or national emergency number
                             CPR 30:2
                           Until AED is attached




                                   AED
                                 assesses
                                 rhythm



   Shock                                                  No shock
  advised                                                  advised


  1 Shock

Immediately resume:                                      Immediately resume:
    CPR 30:2                                                 CPR 30:2
    for 2 min                                                for 2 min


                      Continue until the victim starts
                        to wake up: to move, opens
                       eyes and to breathe normally
In Hospital Resuscitation
                                                Collapsed/sick patient
                                            Shout for HELP & assess patient
                    No                                Signs of life?                      Yes
          Call resuscitation team
                                                                                     Assess ABCDE
                                                                                    Recognise & treat
                                                                               Oxygen, monitoring, iv access
                CPR 30:2
       with oxygen and airway adjuncts
                                                                                  Call resuscitation team
          Apply pads/monitor                                                            If appropriate
    Attempt defibrillation if appropriate
         Advanced Life Support                                                Handover to resuscitation team
        when resuscitation team arrives
6
7




these guidelines that the risk of harm      Adult advanced life
to a rescuer from a defibrillator is very   support
small, particularly if the rescuer is
                                            The most important changes in the 2010
wearing gloves. The focus is now on a
                                            ERC Advanced Life Support (ALS) Guide-
rapid safety check to minimise the pre-     lines include:
shock pause.

                                             ♦♦ Increased    emphasis on the
♦♦ When treating out-of-hospital car-        importance of minimally interrupt-
diac arrest, emergency medical serv-         ed high-quality chest compressions
ices (EMS) personnel should provide          throughout any ALS intervention:
good-quality CPR while a defibrillator       chest compressions are paused briefly
is retrieved, applied and charged, but       only to enable specific interventions.
routine delivery of a pre-specified peri-
od of CPR (e.g., two or three minutes)
before rhythm analysis and a shock is        ♦♦ Increased emphasis on the use of
delivered is no longer recommended.          ‘track and trigger systems’ to detect
For some EMS that have already fully         the deteriorating patient and enable
implemented a pre-specified period of        treatment to prevent in-hospital car-
chest compressions before defibrilla-        diac arrest.
tion, given the lack of convincing data
either supporting or refuting this strat-
egy, it is reasonable for them to con-       ♦♦ Increased awareness of the warn-
tinue this practice.                         ing signs associated with the poten-
                                             tial risk of sudden cardiac death out of
                                             hospital.
♦♦ The use of up to three-stacked
shocks may be considered if VF/VT
occurs during cardiac catheterisation        ♦♦ Removal of the recommendation
or in the early post-operative period        for a pre-specified period of cardiop-
following cardiac surgery. This three-       ulmonary resuscitation (CPR) before
shock strategy may also be considered        out-of-hospital defibrillation following
for an initial, witnessed VF/VT cardiac      cardiac arrest unwitnessed by the EMS.
arrest when the patient is already con-
nected to a manual defibrillator.
                                             ♦♦ Continuation of chest compres-
                                             sions while a defibrillator is charged -
♦♦ Further development of AED pro-           this will minimise the pre-shock pause.
grammes is encouraged – there is a
need for further deployment of AEDs
in both public and residential areas.        ♦♦ The role of the precordial thump is
                                             de-emphasised.
8


                                 Advanced Life Support
                                                       Unresponsive?
                                               Not breathing or only occasional
                                                           gasps


                                                                                                            Call
                                                                                                     Resuscitation Team


                                                           CPR 30:2
                                                  Attach defibrillator/monitor
                                                    Minimise interruptions




                                                                  Assess
                                                                 rhythm


                     Shockable                                                                    Non-shockable
                  (VF/Pulseless VT)                                                               (PEA/Asystole)




                                                              Return of
                     1 Shock                                spontaneous
                                                             circulation




                   Immediately resume:              	 Immediate post cardiac                      Immediately resume:
                       CPR for 2 min                  arrest treatment                               CPR for 2 min
                                                    • Use ABCDE approach
                   Minimise interruptions                                                        Minimise interruptions
                                                    • Controlled oxygenation and
                                                       ventilation
                                                    • 12-lead ECG
                                                    • Treat precipitating cause
                                                    •Temperature control / therapeu-
                                                       tic hypothermia



	 During CPR                                                               	 Reversible causes
•	 Ensure high-quality CPR: rate, depth, recoil                            •	 Hypoxia
•	 Plan actions before interrupting CPR                                    •	 Hypovolaemia
•	 Give oxygen                                                             •	 Hypo-/hyperkalaemia/metabolic
•	 Consider advanced airway and capnography                                •	 Hypothermia
•	 Continuous chest compressions when advanced airway in place
                                                                           •	 Thrombosis
•	 Vascular access (intravenous, intraosseous)
                                                                           •	 Tamponade - cardiac
•	 Give adrenaline every 3-5 min
                                                                           •	 Toxins
•	 Correct reversible causes
                                                                           •	 Tension pneumothorax
Tachycardia (with pulse)
                                                                                   •	 Assess using the ABCDE approach
                                                                                   •	 Ensure oxygen given and obtain IV access
                                                                                   •	 Monitor ECG, BP, SpO2 ,record 12 lead ECG
                                                                                   •	 Identify and treat reversible causes (e.g. electrolyte abnormalities)



                                                                                                    Assess for evidence of adverse signs
      Synchronised DC Shock*                                  Unstable             	      1. Shock	                            2. Syncope                                 Stable                  Is QRS narrow (< 0.12 sec)?
               Up to 3 attempts
                                                                                   	      3. Myocardial ischaemia	             4. Heart failure



                                                                             Broad                                                                                                                Narrow
   •	 Amiodarone 300 mg IV over
      10-20 min and repeat shock;
      followed by:
   •	 Amiodarone 900 mg over 24 h



                                                 Irregular                 Broad QRS                 Regular                                                  Regular                 Narrow QRS                 Irregular
                                                                        Is QRS regular?                                                                                            Is rhythm regular?




                                               Seek expert help                                                                                                                                   Irregular Narrow Complex
                                                                                                                                               •	Use vagal manoeuvres
                                                                                                                                                                                                  Tachycardia
                                                                                                                                               •	Adenosine 6 mg rapid IV bolus;
                                                                                                                                                                                                  Probable atrial fibrillation
                                                                                                                                                 if unsuccessful give 12 mg;
                                                                                                                                                                                                  Control rate with:
                                                                                                                                                 if unsuccessful give further 12 mg.
                                                                                                                                                                                                  •	ß-Blocker or diltiazem
                                                                                                                                               •	Monitor ECG continuously
                                                                                                                                                                                                  •	Consider digoxin or amiodarone if
                                                                                                                                                                                                     evidence of heart failure
                                                                                                                                                                                                  Anticoagulate if duration > 48h



                                                                                       If Ventricular Tachycardia                              Normal sinus rhythm restored?                                             Seek expert help
                                  Possibilities include:                                                                                                                                            No
                                                                                       (or uncertain rhythm):
                                  •	 AF with bundle branch block
                                                                                       •	 Amiodarone 300 mg IV over 20-60
                                     treat as for narrow complex
                                                                                          min; then 900 mg over 24 h
                                  •	 Pre-excited AF                                                                                                              Yes
                                     consider amiodarone
                                                                                       If previously confirmed
                                  •	 Polymorphic VT
                                                                                       SVT with bundle branch block:
                                     (e.g. torsades de pointes -
                                                                                       •	 Give adenosine as for regular
                                     give magnesium 2 g over 10 min)
                                                                                          narrow complex tachycardia
                                                                                                                                               Probable re-entry PSVT:                            Possible atrial flutter
                                                                                                                                               •	 Record 12-lead ECG in sinus rhythm              •	Control rate (e.g. ß-Blocker)
                                                                                                                                               •	 If recurs, give adenosine again &
*Attempted electrical cardioversion is always undertaken under sedation or general anaesthesia                                                     consider choice of anti-arrhythmic
                                                                                                                                                                                                                                            9




                                                                                                                                                   prophylaxis
10


                                                 Bradycardia
                                  •	Assess using the ABCDE approach
                                  •	Ensure oxygen given and obtain IV access
                                  •	Monitor ECG, BP, SpO2 ,record 12 lead ECG
                                  •	Identify and treat reversible causes (e.g. electrolyte abnormalities)




                                          Assess for evidence of adverse signs:
                                          1 Shock
                            Yes           2 Syncope                                                         No
                                          3 Myocardial ischaemia
                                          4 Heart failure


               Atropine
              500 mcg IV



             Satisfactory
                                                                     Yes
             Response?


                 No                                                                              Risk of asystole?
                                                                                                 • Recent asystole
                                                                     Yes                         • Möbitz II AV block
                                                                                                 • Complete heart block with broad QRS
                                                                                                 • Ventricular pause > 3s

     Interim measures:

     • Atropine 500 mcg IV repeat
        to maximum of 3 mg
     • Isoprenaline 5 mcg min-1
     • Adrenaline 2-10 mcg min-1
     • Alternative drugs*                                                                                         No
     OR
     • Transcutaneous pacing




          Seek expert help                                                                                     Observe
     Arrange transvenous pacing

     * Alternatives include:
        •	 Aminophylline
        •	 Dopamine
        •	 Glucagon (if beta-blocker or calcium channel
           blocker overdose)
        •	 Glycopyrrolate can be used instead of atropine
11




♦♦ The use of up to three quick suc-
cessive (stacked) shocks for ventricular    ♦♦ The potential role of ultrasound
fibrillation/pulseless ventricular tachy-   imaging during ALS is recognised.
cardia (VF/VT) occurring in the cardiac
catheterisation laboratory or in the
immediate post-operative period fol-        ♦♦ Recognition of the potential harm
lowing cardiac surgery.                     caused by hyperoxaemia after ROSC is
                                            achieved: once ROSC has been estab-
                                            lished and the oxygen saturation of
♦♦ Delivery of drugs via a tracheal tube    arterial blood (SaO2) can be moni-
is no longer recommended – if intrave-      tored reliably (by pulse oximetry and/
nous access cannot be achieved, drugs       or arterial blood gas analysis), inspired
should be given by the intraosseous         oxygen is titrated to achieve a SaO2 of
(IO) route.                                 94 – 98%.


♦♦ When treating VF/VT cardiac arrest,      ♦♦ Much greater detail and emphasis
adrenaline 1 mg is given after the third    on the treatment of the post-cardiac
shock once chest compressions have          arrest syndrome.
restarted and then every 3-5 min-
utes (during alternate cycles of CPR).
Amiodarone 300 mg is also given after       ♦♦ Recognition that implementation
the third shock.                            of a comprehensive, structured post
                                            resuscitation treatment protocol may
                                            improve survival in cardiac arrest vic-
♦♦ Atropine is no longer recommend-         tims after ROSC.
ed for routine use in asystole or pulse-
less electrical activity (PEA).
                                            ♦♦ Increased emphasis on the use
                                            of primary percutaneous coronary
♦♦ Reduced emphasis on early tra-           intervention in appropriate (includ-
cheal intubation unless achieved by         ing comatose) patients with sustained
highly skilled individuals with minimal     ROSC after cardiac arrest.
interruption to chest compressions.

                                            ♦♦ Revision of the recommendation
♦♦ Increased emphasis on the use of         for glucose control: in adults with sus-
capnography to confirm and continu-         tained ROSC after cardiac arrest, blood
ally monitor tracheal tube placement,       glucose values >10 mmol l-1 (>180 mg
quality of CPR and to provide an early      dl-1) should be treated but hypoglycae-
indication of return of spontaneous         mia must be avoided.
circulation (ROSC).
12



                                                                                                      ACS
                                   Patient with clinical signs and symptoms of ACS


                                                                                           12 lead ECG


                       ST elevation
        ≥ 0.1 mV in ≥ 2 adjacent limb leads and/                                                                                         Other ECG alterations
          or ≥ 0.2 mV in ≥ adjacent chest leads                                                                                                        (or normal ECG)
               or (presumably) new LBBB




                                                                                                                = NSTEMI if troponins                                = UAP if troponins
                                                                                                                   (T or I) positive                                  remain negative


                              STEMI

                                                                                                                                               non-STEMI-ACS
                                                                                                                                  High risk
                                                                                                                                  • dynamic ECG changes
                                                                                                                                  • ST depression
                                                                                                                                  • haemodynamic/rhythm instability
                                                                                                                                  • diabetes mellitus




                                                                                                   ECG
                                                                                                       ECG

                                                            Pain relief 	 Nitroglycerin sl if systolic BP > 90 mmHg
                                                            	             ± Morphine (repeated doses) of 3-5 mg until pain free




                                                        Antiplatelet treatment	 160-325mg Acetylsalicylic acid chewed tablet (or iv)
                                                        	                                     75 – 600 mg Clopidogrel according to strategy*




                                             STEMI                                                                                                Non-STEMI-ACS



     Thrombolysis preferred if                              PCI preferred if                                        Early invasive strategy#                       Conservative
     no contraindications and                               • timely and available in a high                        UFH                                            or delayed invasive strategy#
     inappropriate delay to PCI                                volume center
                                                                                                                    Enoxaparin or bivalirudin may be               UFH (fondaparinux or bivalirudin
                                                            • contraindications for fibrinolysis
                                                               cardiogenic shock (or severe left                    considered                                     may be considered in pts with high
     Adjunctive therapy:                                       ventricular failure)                                                                                bleeding risk)
     UFH, enoxaparin or fondaparinux                        Adjunctive therapy:
                                                            UFH, enoxaparin or bivalirudin may
                                                            be considered



                   # According to risk stratification
13




 ♦♦ Use of therapeutic hypothermia to        ♦♦ The role of chest pain observation
 include comatose survivors of cardiac       units (CPUs) is to identify, by using
 arrest associated initially with non-       repeated clinical examinations, ECG
 shockable rhythms as well shockable         and biomarker testing, those patients
 rhythms. The lower level of evidence        who require admission for invasive
 for use after cardiac arrest from non-      procedures. This may include provoca-
 shockable rhythms is acknowledged.          tive testing and, in selected patients,
                                             imaging procedures such as cardiac
                                             computed tomography, magnetic res-
 ♦♦ Recognition that many of the             onance imaging etc.
 accepted predictors of poor outcome
 in comatose survivors of cardiac arrest
 are unreliable, especially if the patient   ♦♦ Non-steroidal   anti-inflammatory
 has been treated with therapeutic           drugs (NSAIDs) should be avoided.
 hypothermia.

                                             ♦♦ Nitrates should not be used for
Initial management of                        diagnostic purposes.
acute coronary syndromes
Changes in the management of acute           ♦♦ Supplementary oxygen is to be giv-
coronary syndrome since the 2005             en only to those patients with hypox-
guidelines include:                          aemia, breathlessness or pulmonary
                                             congestion. Hyperoxaemia may be
 ♦♦ The term non-ST-elevation myo-           harmful in uncomplicated infarction.
 cardial infarction-acute coronary syn-
 drome (non-STEMI-ACS) has been
 introduced for both NSTEMI and              ♦♦ Guidelines for treatment with
 unstable angina pectoris because the        acetyl salicylic acid (ASA) have been
 differential diagnosis is dependent on      made more liberal: ASA may now be
 biomarkers that may be detectable           given by bystanders with or without
 only after several hours, whereas deci-     EMS dispatcher assistance.
 sions on treatment are dependent on
 the clinical signs at presentation.
                                             ♦♦ Revised guidance for new anti-
                                             platelet and anti-thrombin treatment
 ♦♦ History,   clinical examinations,        for patients with STEMI and non-STE-
 biomarkers, ECG criteria and risk scores    MI-ACS based on therapeutic strategy.
 are unreliable for the identification of
 patients who may be safely discharged
 early.
14




     ♦♦ Gp IIb/IIIa inhibitors before angiog-        - Angiography and, if necessary, PCI
     raphy/percutaneous coronary inter-              may be reasonable in patients with
     vention (PCI) are discouraged.                  return of spontaneous circulation
                                                     (ROSC) after cardiac arrest and may
                                                     be part of a standardised post-cardi-
     ♦♦ The    reperfusion strategy in               ac arrest protocol.
     ST-elevation myocardial infarction has
     been updated:                                   - To achieve these goals, the creation
                                                     of networks including EMS, non PCI
       - Primary PCI (PPCI) is the preferred         capable hospitals and PCI hospitals
       reperfusion strategy provided it is           is useful.
       performed in a timely manner by an
       experienced team.
                                                   ♦♦ Recommendations for the use
       - A nearby hospital may be bypassed         of beta-blockers are more restrict-
       by emergency medical services               ed: there is no evidence for routine
       (EMS) provided PPCI can be achieved         intravenous beta-blockers except in
       without too much delay.                     specific circumstances such as for
                                                   the treatment of tachyarrhythmias.
       - The acceptable delay between start        Otherwise, beta-blockers should be
       of fibrinolysis and first balloon infla-    started in low doses only after the
       tion varies widely between about 45         patient is stabilised.
       and 180 minutes depending on inf-
       arct localisation, age of the patient,
       and duration of symptoms.                   ♦♦ Guidelines on the use of prophy-
                                                   lactic anti-arrhythmics angiotensin,
       - ‘Rescue PCI’ should be undertaken         converting enzyme (ACE) inhibitors/
       if fibrinolysis fails.                      angiotensin receptor blockers (ARBs)
                                                   and statins are unchanged.
       - The strategy of routine PCI imme-
       diately after fibrinolysis (‘facilitated
       PCI’) is discouraged.
                                                  Paediatric life support
       - Patients with successful fibrinolysis
       but not in a PCI-capable hospital          Major changes in these new guidelines
       should be transferred for angiog-          for paediatric life support include:
       raphy and eventual PCI, performed
       optimally 6 – 24 hours after fibri-         ♦♦ Recognition of cardiac arrest -
       nolysis (the ‘pharmaco-invasive’            Healthcare providers cannot reliably
       approach).                                  determine the presence or absence
                                                   of a pulse in less than 10 seconds in
15




infants or children. Healthcare provid-     minimise no-flow time. Compress
ers should look for signs of life and if    the chest to at least 1/3 of the ante-
they are confident in the technique,        rior-posterior chest diameter in all
they may add pulse palpation for            children (i.e., approximately 4 cm in
diagnosing cardiac arrest and decide        infants and approximately 5 cm in chil-
whether they should begin chest com-        dren). Subsequent complete release is
pressions or not. The decision to begin     emphasised. For both infants and chil-
CPR must be taken in less than 10           dren, the compression rate should be
seconds. According to the child’s age,      at least 100 but not greater than 120
carotid (children), brachial (infants) or   min-1. The compression technique for
femoral pulse (children and infants)        infants includes two-finger compres-
checks may be used.                         sion for single rescuers and the two-
                                            thumb encircling technique for two
                                            or more rescuers. For older children,
♦♦ The compression ventilation (CV)         a one- or two-hand technique can be
ratio used for children should be based     used, according to rescuer preference.
on whether one, or more than one
rescuer is present. Lay rescuers, who
usually learn only single-rescuer tech-     ♦♦ Automated external defibrillators
niques, should be taught to use a ratio     (AEDs) are safe and successful when
of 30 compressions to 2 ventilations,       used in children older than one year
which is the same as the adult guide-       of age. Purpose-made paediatric pads
lines and enables anyone trained in         or software attenuate the output of
BLS to resuscitate children with mini-      the machine to 50–75 J and these are
mal additional information. Rescuers        recommended for children aged 1-8
with a duty to respond should learn         years. If an attenuated shock or a man-
and use a 15:2 CV ratio; however, they      ually adjustable machine is not avail-
can use the 30:2 ratio if they are alone,   able, an unmodified adult AED may
particularly if they are not achieving      be used in children older than 1 year.
an adequate number of compressions.         There are case reports of successful
Ventilation remains a very important        use of AEDs in children aged less than
component of CPR in asphyxial arrests.      1 year; in the rare case of a shockable
Rescuers who are unable or unwilling        rhythm occurring in a child less than
to provide mouth-to-mouth ventila-          1 year, it is reasonable to use an AED
tion should be encouraged to perform        (preferably with dose attenuator).
at least compression-only CPR.

                                            ♦♦ To reduce the no flow time, when
♦♦ The emphasis is on achieving             using a manual defibrillator, chest
quality compressions of an adequate         compressions are continued while
depth with minimal interruptions to         applying and charging the paddles or
16




      Paediatric Basic Life Support
     Health professionals with a duty to respond

                        UNRESPONSIVE?



                          Shout for help



                          Open airway



                  NOT BREATHING NORMALLY?



                         5 rescue breaths



                       NO SIGNS OF LIFE?



                     15 chest compressions



                        2 rescue breaths
                        15 compressions


          Call cardiac arrest team or Paediatric ALS team
17



                 Paediatric Advanced Life Support

                                                   Unresponsive?
                                        Not breathing or only occasional gasps




                                            CPR (5 initial breaths then 15:2)                           Call Resuscitation
                                             Attach defibrillator/monitor                                     Team
                                               Minimise interruptions                                   (1 min CPR first, if alone)




                                                            Assess
                                                           rhythm



                   Shockable                                                                   Non-shockable
                (VF/Pulseless VT)                                                              (PEA/Asystole)




                                                           Return of
               1 Shock 4 J/Kg                            spontaneous
                                                          circulation




               Immediately resume:                	 Immediate post cardiac                  Immediately resume:
                   CPR for 2 min                     arrest treatment                           CPR for 2 min
               Minimise interruptions             • Use ABCDE approach                      Minimise interruptions
                                                  • Controlled oxygenation and
                                                     ventilation
                                                  • Investigations
                                                  • Treat precipitating cause
                                                  • Temperature control
                                                  • Therapeutic hypothermia?



	 During CPR                                                          	 Reversible causes
                                                                      • Hypoxia
• Ensure high-quality CPR: rate, depth, recoil
• Plan actions before interrupting CPR                                • Hypovolaemia
• Give oxygen                                                         • Hypo-/hyperkalaemia/metabolic
• Vascular access (intravenous, intraosseous)                         • Hypothermia
• Give adrenaline every 3-5 min
• Consider advanced airway and capnography                            • Tension pneumothorax
• Continuous chevvst compressions when advanced airway                • Toxins
  in place                                                            • Tamponade - cardiac
• Correct reversible causes                                           • Thromboembolism
18


                                            Newborn Life Support
     At all stages ask: Do you need HELP?                    Dry the baby                         Birth
                                                  Remove any wet towels and cover
                                                   Start the clock or note the time



                                                            Assess (tone),                        30 sec
                                                       breathing and heart rate



                                                      If gasping or not breathing
                                                            Open the airway
                                                         Give 5 inflation breaths
                                                          Consider SpO2 monitoring                60 sec


                                                                    Re-assess
                                                           If no increase in heart rate
                                                           Look for chest movement




                                                                                                 Acceptable*
                                                              If chest not moving
                                                                                                 pre-ductal SpO2
                                                       Recheck head position
                                                 Consider two-person airway control              2 min : 60%
                                                    or other airway manoeuvres                   3 min : 70%
                                                      Repeat inflation breaths                   4 min : 80%
                                                          Consider SpO2 monitoring
                                                                                                 5 min : 85%
                                                             Look for a response
                                                                                                 10 min : 90%




                                                       If no increase in heart rate
                                                       Look for chest movement



                                                       When the chest is moving
                                            If the heart rate is not detectable or slow (< 60)
                                                        Start chest compressions
                                                         3 compressions to each breath




                                                            Reassess heart rate
                                                             every 30 seconds
                                            If the heart rate is not detectable or slow (< 60)
                                                       Consider venous access and drugs
19




self-adhesive pads (if the size of the       ♦♦ Implementation      of a rapid
child’s chest allows this). Chest com-       response system in a paediatric in-
pressions are paused briefly once the        patient setting may reduce rates of
defibrillator is charged to deliver the      cardiac and respiratory arrest and in-
shock. For simplicity and consistency        hospital mortality.
with adult BLS and ALS guidance, a
single-shock strategy using a non-
escalating dose of 4 J kg-1 (preferably      ♦♦ New topics in the 2010 guidelines
biphasic, but monophasic is accepta-         include channelopathies and several
ble) is recommended for defibrillation       new special circumstances: trauma,
in children.                                 single ventricle pre and post 1st stage
                                             repair, post Fontan circulation, and
                                             pulmonary hypertension.
♦♦ Cuffed tracheal tubes can be used
safely in infants and young children.
The size should be selected by apply-      Resuscitation of babies at
ing a validated formula.                   birth
                                           The following are the main changes that
♦♦ The safety and value of using cricoid   have been made to the guidelines for re-
pressure during tracheal intubation is     suscitation at birth in 2010:
not clear. Therefore, the application of
cricoid pressure should be modified or       ♦♦ For uncompromised babies, a
discontinued if it impedes ventilation       delay in cord clamping of at least one
or the speed or ease of intubation.          minute from the complete delivery of
                                             the infant, is now recommended. As
                                             yet there is insufficient evidence to
♦♦ Monitoring exhaled carbon diox-           recommend an appropriate time for
ide (CO2), ideally by capnography, is        clamping the cord in babies who are
helpful to confirm correct tracheal          severely compromised at birth.
tube position and recommended dur-
ing CPR to help assess and optimise its
quality.                                     ♦♦ For term infants, air should be used
                                             for resuscitation at birth. If, despite
                                             effective ventilation, oxygenation (ide-
♦♦ Once spontaneous circulation is           ally guided by oximetry) remains unac-
restored, inspired oxygen should be          ceptable, use of a higher concentration
titrated to limit the risk of hyperoxa-      of oxygen should be considered.
emia.
20




     ♦♦ Preterm babies less than 32 weeks       start mask ventilation, particularly if
     gestation may not reach the same           there is persistent bradycardia.
     transcutaneous oxygen saturations in
     air as those achieved by term babies.
     Therefore blended oxygen and air           ♦♦ If adrenaline is given then the
     should be given judiciously and its use    intravenous route is recommended
     guided by pulse oximetry. If a blend       using a dose of 10-30 microgram kg-1.
     of oxygen and air is not available use     If the tracheal route is used, it is likely
     what is available.                         that a dose of at least 50-100 micro-
                                                gram kg-1 will be needed to achieve
                                                a similar effect to 10 microgram kg-1
     ♦♦ Preterm babies of less than 28          intravenously.
     weeks gestation should be completely
     covered in a food-grade plastic wrap or
     bag up to their necks, without drying,     ♦♦ Detection of exhaled carbon diox-
     immediately after birth. They should       ide in addition to clinical assessment
     then be nursed under a radiant heater      is recommended as the most reliable
     and stabilised. They should remain         method to confirm placement of a tra-
     wrapped until their temperature has        cheal tube in neonates with spontane-
     been checked after admission. For          ous circulation.
     these infants delivery room tempera-
     tures should be at least 26°C.
                                                ♦♦ Newly born infants born at term or
                                                near-term with evolving moderate to
     ♦♦ The recommended compression:            severe hypoxic – ischaemic encepha-
     ventilation ratio for CPR remains at 3:1   lopathy should, where possible, be
     for newborn resuscitation.                 treated with therapeutic hypother-
                                                mia. This does not affect immediate
                                                resuscitation but is important for post-
     ♦♦ Attempts to aspirate meconium           resuscitation care.
     from the nose and mouth of the
     unborn baby, while the head is still on
     the perineum, are not recommended.
     If presented with a floppy, apnoeic
     baby born through meconium it is rea-
     sonable to rapidly inspect the orophar-
     ynx to remove potential obstructions.
     If appropriate expertise is available,
     tracheal intubation and suction may
     be useful. However, if attempted intu-
     bation is prolonged or unsuccessful,
21




Principles of education in                   ♦♦ Basic and advanced life support
resuscitation                                knowledge and skills deteriorate in as
                                             little as three to six months. The use
The key issues identified by the Educa-      of frequent assessments will identify
tion, Implementation and Teams (EIT)
                                             those individuals who require refresh-
task force of the International Liaison
Committee on Resuscitation (ILCOR)           er training to help maintain their
during the Guidelines 2010 evidence          knowledge and skills.
evaluation process are:

                                             ♦♦ CPR prompt or feedback devices
 ♦♦ Educational interventions should         improve CPR skill acquisition and
 be evaluated to ensure that they            retention and should be considered
 reliably achieve the learning objec-        during CPR training for laypeople and
 tives. The aim is to ensure that learn-     healthcare professionals.
 ers acquire and retain the skills and
 knowledge that will enable them to
 act correctly in actual cardiac arrests     ♦♦ An increased emphasis on non-
 and improve patient outcomes.               technical skills (NTS) such as leader-
                                             ship, teamwork, task management
                                             and structured communication will
 ♦♦ Short video/computer self-instruc-       help improve the performance of CPR
 tion courses, with minimal or no            and patient care.
 instructor coaching, combined with
 hands-on practice can be considered
 as an effective alternative to instruc-     ♦♦ Team briefings to plan for resusci-
 tor-led basic life support (CPR and         tation attempts, and debriefings based
 AED) courses.                               on performance during simulated or
                                             actual resuscitation attempts should
                                             be used to help improve resuscitation
 ♦♦ Ideally all citizens should be trained   team and individual performance.
 in standard CPR that includes com-
 pressions and ventilations. There are
 circumstances however where train-          ♦♦ Research about the impact of
 ing in compression-only CPR is appro-       resuscitation training on actual patient
 priate (e.g., opportunistic training        outcomes is limited. Although manikin
 with very limited time). Those trained      studies are useful, researchers should
 in compression-only CPR should be           be encouraged to study and report the
 encouraged to learn standard CPR.           impact of educational interventions
                                             on actual patient outcomes.
22




                          Edited by Jerry Nolan



                                     Authors

     Jerry P. Nolan                              Charles Deakin

     Jasmeet Soar                                Rudolph W. Koster

     David A. Zideman                            Jonathan Wyllie

     Dominique Biarent                           Bernd Böttiger

     Leo L. Bossaert                             on behalf of the ERC Guidelines
                                                 Writing Group




     Acknowledgements: The ERC staff members Annelies Pické, Christophe Bostyn,
     Jeroen Janssens, Hilary Phelan and Bart Vissers for their administrative support. Het
     Geel Punt bvba, Melkouwen 42a, 2590 Berlaar, Belgium (hgp@hetgeelpunt.be) for
     creating the algorithms and Griet Demesmaeker (grietdemesmaeker@gmail.com)
     for the cover design.
23




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You can choose between

  * Full membership on paper and electronic
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Full members on paper and electronic (€ 140 for 12 months) enjoy:

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Full members electronic version only (€ 115 for 12 months) enjoy:

     - online access to Resuscitation (including all previous issues)
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These benefits add to all the benefits you experienced as a web member:

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IMPORTANT
ERC currently offers combined membership possibilities with a number of
organisations, with an additional discount: Belgian Resuscitation Council,
Norwegian Resuscitation Council, Resuscitation Council UK.
If you are already a member of one of these organisations, please contact
their secretariat for additional information about combined membership
possibilities.
www.erc.edu

www.CPRguidelines.eu

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Executive summary vf20101018

  • 1. european resuscitation council Summary of the main changes in the Resuscitation Guidelines ERC Guidelines 2010
  • 2. 2 European Resuscitation Council To p r e s e r v e h u m a n l i f e b y m a k i n g high quality resuscitation available to all The Network of National Resuscitation Councils Published by: European Resuscitation Council Secretariat vzw, Drie Eikenstraat 661 - BE 2650 Edegem - Belgium Website: www.erc.edu Email: info@erc.edu Tel: +32 3 826 93 21 © European Resuscitation Council 2010. All rights reserved. We encourage you to send this document to other persons as a whole in order to disseminate the ERC Guidelines. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise for commercial purposes, without the prior written permission of the ERC. Version1.2 Disclaimer: No responsibility is assumed by the authors and the publisher for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions or ideas contained in the material herein.
  • 3. 3 Summary of main changes since 2005 Guidelines Basic life support improve the quality of CPR perform- ance and provide feedback to pro- Changes in basic life support (BLS) since fessional rescuers during debriefing the 2005 guidelines include: sessions. ♦♦ Dispatchers should be trained to interrogate callers with strict protocols Electrical therapies: to elicit information. This information automated external defi- should focus on the recognition of brillators, defibrillation, unresponsiveness and the quality of cardioversion and pacing breathing. In combination with unre- sponsiveness, absence of breathing or The most important changes in the 2010 any abnormality of breathing should ERC Guidelines for electrical therapies start a dispatch protocol for suspect- include: ed cardiac arrest. The importance of gasping as sign of cardiac arrest is emphasised. ♦♦ The importance of early, uninter- rupted chest compressions is empha- sised throughout these guidelines. ♦♦ All rescuers, trained or not, should provide chest compressions to victims of cardiac arrest. A strong empha- ♦♦ Much greater emphasis on mini- sis on delivering high quality chest mising the duration of the pre-shock compressions remains essential. The and post-shock pauses; the continua- aim should be to push to a depth of tion of compressions during charging at least 5 cm at a rate of at least 100 of the defibrillator is recommended. compressions min-1, to allow full chest recoil, and to minimise interruptions in chest compressions. Trained rescu- ♦♦ Immediate resumption of chest ers should also provide ventilations compressions following defibrillation with a compression–ventilation (CV) is also emphasised; in combination ratio of 30:2. Telephone-guided chest with continuation of compressions compression-only CPR is encouraged during defibrillator charging, the for untrained rescuers. delivery of defibrillation should be achievable with an interruption in chest compressions of no more than 5 ♦♦ The use of prompt/feedback devic- seconds. es during CPR will enable immediate feedback to rescuers and is encour- aged. The data stored in rescue equip- ♦♦ Safety of the rescuer remains par- ment can be used to monitor and amount, but there is recognition in
  • 4. 4 Adult Basic Life Support UNRESPONSIVE? Shout for help Open airway NOT BREATHING NORMALLY? Call 112* 30 chest compressions 2 rescue breaths 30 compressions *or national emergency number
  • 5. 5 Automated External Defibrillation Unresponsive? Call for help Open airway Not breathing normally Send or go for AED Call 112* * or national emergency number CPR 30:2 Until AED is attached AED assesses rhythm Shock No shock advised advised 1 Shock Immediately resume: Immediately resume: CPR 30:2 CPR 30:2 for 2 min for 2 min Continue until the victim starts to wake up: to move, opens eyes and to breathe normally
  • 6. In Hospital Resuscitation Collapsed/sick patient Shout for HELP & assess patient No Signs of life? Yes Call resuscitation team Assess ABCDE Recognise & treat Oxygen, monitoring, iv access CPR 30:2 with oxygen and airway adjuncts Call resuscitation team Apply pads/monitor If appropriate Attempt defibrillation if appropriate Advanced Life Support Handover to resuscitation team when resuscitation team arrives 6
  • 7. 7 these guidelines that the risk of harm Adult advanced life to a rescuer from a defibrillator is very support small, particularly if the rescuer is The most important changes in the 2010 wearing gloves. The focus is now on a ERC Advanced Life Support (ALS) Guide- rapid safety check to minimise the pre- lines include: shock pause. ♦♦ Increased emphasis on the ♦♦ When treating out-of-hospital car- importance of minimally interrupt- diac arrest, emergency medical serv- ed high-quality chest compressions ices (EMS) personnel should provide throughout any ALS intervention: good-quality CPR while a defibrillator chest compressions are paused briefly is retrieved, applied and charged, but only to enable specific interventions. routine delivery of a pre-specified peri- od of CPR (e.g., two or three minutes) before rhythm analysis and a shock is ♦♦ Increased emphasis on the use of delivered is no longer recommended. ‘track and trigger systems’ to detect For some EMS that have already fully the deteriorating patient and enable implemented a pre-specified period of treatment to prevent in-hospital car- chest compressions before defibrilla- diac arrest. tion, given the lack of convincing data either supporting or refuting this strat- egy, it is reasonable for them to con- ♦♦ Increased awareness of the warn- tinue this practice. ing signs associated with the poten- tial risk of sudden cardiac death out of hospital. ♦♦ The use of up to three-stacked shocks may be considered if VF/VT occurs during cardiac catheterisation ♦♦ Removal of the recommendation or in the early post-operative period for a pre-specified period of cardiop- following cardiac surgery. This three- ulmonary resuscitation (CPR) before shock strategy may also be considered out-of-hospital defibrillation following for an initial, witnessed VF/VT cardiac cardiac arrest unwitnessed by the EMS. arrest when the patient is already con- nected to a manual defibrillator. ♦♦ Continuation of chest compres- sions while a defibrillator is charged - ♦♦ Further development of AED pro- this will minimise the pre-shock pause. grammes is encouraged – there is a need for further deployment of AEDs in both public and residential areas. ♦♦ The role of the precordial thump is de-emphasised.
  • 8. 8 Advanced Life Support Unresponsive? Not breathing or only occasional gasps Call Resuscitation Team CPR 30:2 Attach defibrillator/monitor Minimise interruptions Assess rhythm Shockable Non-shockable (VF/Pulseless VT) (PEA/Asystole) Return of 1 Shock spontaneous circulation Immediately resume: Immediate post cardiac Immediately resume: CPR for 2 min arrest treatment CPR for 2 min • Use ABCDE approach Minimise interruptions Minimise interruptions • Controlled oxygenation and ventilation • 12-lead ECG • Treat precipitating cause •Temperature control / therapeu- tic hypothermia During CPR Reversible causes • Ensure high-quality CPR: rate, depth, recoil • Hypoxia • Plan actions before interrupting CPR • Hypovolaemia • Give oxygen • Hypo-/hyperkalaemia/metabolic • Consider advanced airway and capnography • Hypothermia • Continuous chest compressions when advanced airway in place • Thrombosis • Vascular access (intravenous, intraosseous) • Tamponade - cardiac • Give adrenaline every 3-5 min • Toxins • Correct reversible causes • Tension pneumothorax
  • 9. Tachycardia (with pulse) • Assess using the ABCDE approach • Ensure oxygen given and obtain IV access • Monitor ECG, BP, SpO2 ,record 12 lead ECG • Identify and treat reversible causes (e.g. electrolyte abnormalities) Assess for evidence of adverse signs Synchronised DC Shock* Unstable 1. Shock 2. Syncope Stable Is QRS narrow (< 0.12 sec)? Up to 3 attempts 3. Myocardial ischaemia 4. Heart failure Broad Narrow • Amiodarone 300 mg IV over 10-20 min and repeat shock; followed by: • Amiodarone 900 mg over 24 h Irregular Broad QRS Regular Regular Narrow QRS Irregular Is QRS regular? Is rhythm regular? Seek expert help Irregular Narrow Complex • Use vagal manoeuvres Tachycardia • Adenosine 6 mg rapid IV bolus; Probable atrial fibrillation if unsuccessful give 12 mg; Control rate with: if unsuccessful give further 12 mg. • ß-Blocker or diltiazem • Monitor ECG continuously • Consider digoxin or amiodarone if evidence of heart failure Anticoagulate if duration > 48h If Ventricular Tachycardia Normal sinus rhythm restored? Seek expert help Possibilities include: No (or uncertain rhythm): • AF with bundle branch block • Amiodarone 300 mg IV over 20-60 treat as for narrow complex min; then 900 mg over 24 h • Pre-excited AF Yes consider amiodarone If previously confirmed • Polymorphic VT SVT with bundle branch block: (e.g. torsades de pointes - • Give adenosine as for regular give magnesium 2 g over 10 min) narrow complex tachycardia Probable re-entry PSVT: Possible atrial flutter • Record 12-lead ECG in sinus rhythm • Control rate (e.g. ß-Blocker) • If recurs, give adenosine again & *Attempted electrical cardioversion is always undertaken under sedation or general anaesthesia consider choice of anti-arrhythmic 9 prophylaxis
  • 10. 10 Bradycardia • Assess using the ABCDE approach • Ensure oxygen given and obtain IV access • Monitor ECG, BP, SpO2 ,record 12 lead ECG • Identify and treat reversible causes (e.g. electrolyte abnormalities) Assess for evidence of adverse signs: 1 Shock Yes 2 Syncope No 3 Myocardial ischaemia 4 Heart failure Atropine 500 mcg IV Satisfactory Yes Response? No Risk of asystole? • Recent asystole Yes • Möbitz II AV block • Complete heart block with broad QRS • Ventricular pause > 3s Interim measures: • Atropine 500 mcg IV repeat to maximum of 3 mg • Isoprenaline 5 mcg min-1 • Adrenaline 2-10 mcg min-1 • Alternative drugs* No OR • Transcutaneous pacing Seek expert help Observe Arrange transvenous pacing * Alternatives include: • Aminophylline • Dopamine • Glucagon (if beta-blocker or calcium channel blocker overdose) • Glycopyrrolate can be used instead of atropine
  • 11. 11 ♦♦ The use of up to three quick suc- cessive (stacked) shocks for ventricular ♦♦ The potential role of ultrasound fibrillation/pulseless ventricular tachy- imaging during ALS is recognised. cardia (VF/VT) occurring in the cardiac catheterisation laboratory or in the immediate post-operative period fol- ♦♦ Recognition of the potential harm lowing cardiac surgery. caused by hyperoxaemia after ROSC is achieved: once ROSC has been estab- lished and the oxygen saturation of ♦♦ Delivery of drugs via a tracheal tube arterial blood (SaO2) can be moni- is no longer recommended – if intrave- tored reliably (by pulse oximetry and/ nous access cannot be achieved, drugs or arterial blood gas analysis), inspired should be given by the intraosseous oxygen is titrated to achieve a SaO2 of (IO) route. 94 – 98%. ♦♦ When treating VF/VT cardiac arrest, ♦♦ Much greater detail and emphasis adrenaline 1 mg is given after the third on the treatment of the post-cardiac shock once chest compressions have arrest syndrome. restarted and then every 3-5 min- utes (during alternate cycles of CPR). Amiodarone 300 mg is also given after ♦♦ Recognition that implementation the third shock. of a comprehensive, structured post resuscitation treatment protocol may improve survival in cardiac arrest vic- ♦♦ Atropine is no longer recommend- tims after ROSC. ed for routine use in asystole or pulse- less electrical activity (PEA). ♦♦ Increased emphasis on the use of primary percutaneous coronary ♦♦ Reduced emphasis on early tra- intervention in appropriate (includ- cheal intubation unless achieved by ing comatose) patients with sustained highly skilled individuals with minimal ROSC after cardiac arrest. interruption to chest compressions. ♦♦ Revision of the recommendation ♦♦ Increased emphasis on the use of for glucose control: in adults with sus- capnography to confirm and continu- tained ROSC after cardiac arrest, blood ally monitor tracheal tube placement, glucose values >10 mmol l-1 (>180 mg quality of CPR and to provide an early dl-1) should be treated but hypoglycae- indication of return of spontaneous mia must be avoided. circulation (ROSC).
  • 12. 12 ACS Patient with clinical signs and symptoms of ACS 12 lead ECG ST elevation ≥ 0.1 mV in ≥ 2 adjacent limb leads and/ Other ECG alterations or ≥ 0.2 mV in ≥ adjacent chest leads (or normal ECG) or (presumably) new LBBB = NSTEMI if troponins = UAP if troponins (T or I) positive remain negative STEMI non-STEMI-ACS High risk • dynamic ECG changes • ST depression • haemodynamic/rhythm instability • diabetes mellitus ECG ECG Pain relief Nitroglycerin sl if systolic BP > 90 mmHg ± Morphine (repeated doses) of 3-5 mg until pain free Antiplatelet treatment 160-325mg Acetylsalicylic acid chewed tablet (or iv) 75 – 600 mg Clopidogrel according to strategy* STEMI Non-STEMI-ACS Thrombolysis preferred if PCI preferred if Early invasive strategy# Conservative no contraindications and • timely and available in a high UFH or delayed invasive strategy# inappropriate delay to PCI volume center Enoxaparin or bivalirudin may be UFH (fondaparinux or bivalirudin • contraindications for fibrinolysis cardiogenic shock (or severe left considered may be considered in pts with high Adjunctive therapy: ventricular failure) bleeding risk) UFH, enoxaparin or fondaparinux Adjunctive therapy: UFH, enoxaparin or bivalirudin may be considered # According to risk stratification
  • 13. 13 ♦♦ Use of therapeutic hypothermia to ♦♦ The role of chest pain observation include comatose survivors of cardiac units (CPUs) is to identify, by using arrest associated initially with non- repeated clinical examinations, ECG shockable rhythms as well shockable and biomarker testing, those patients rhythms. The lower level of evidence who require admission for invasive for use after cardiac arrest from non- procedures. This may include provoca- shockable rhythms is acknowledged. tive testing and, in selected patients, imaging procedures such as cardiac computed tomography, magnetic res- ♦♦ Recognition that many of the onance imaging etc. accepted predictors of poor outcome in comatose survivors of cardiac arrest are unreliable, especially if the patient ♦♦ Non-steroidal anti-inflammatory has been treated with therapeutic drugs (NSAIDs) should be avoided. hypothermia. ♦♦ Nitrates should not be used for Initial management of diagnostic purposes. acute coronary syndromes Changes in the management of acute ♦♦ Supplementary oxygen is to be giv- coronary syndrome since the 2005 en only to those patients with hypox- guidelines include: aemia, breathlessness or pulmonary congestion. Hyperoxaemia may be ♦♦ The term non-ST-elevation myo- harmful in uncomplicated infarction. cardial infarction-acute coronary syn- drome (non-STEMI-ACS) has been introduced for both NSTEMI and ♦♦ Guidelines for treatment with unstable angina pectoris because the acetyl salicylic acid (ASA) have been differential diagnosis is dependent on made more liberal: ASA may now be biomarkers that may be detectable given by bystanders with or without only after several hours, whereas deci- EMS dispatcher assistance. sions on treatment are dependent on the clinical signs at presentation. ♦♦ Revised guidance for new anti- platelet and anti-thrombin treatment ♦♦ History, clinical examinations, for patients with STEMI and non-STE- biomarkers, ECG criteria and risk scores MI-ACS based on therapeutic strategy. are unreliable for the identification of patients who may be safely discharged early.
  • 14. 14 ♦♦ Gp IIb/IIIa inhibitors before angiog- - Angiography and, if necessary, PCI raphy/percutaneous coronary inter- may be reasonable in patients with vention (PCI) are discouraged. return of spontaneous circulation (ROSC) after cardiac arrest and may be part of a standardised post-cardi- ♦♦ The reperfusion strategy in ac arrest protocol. ST-elevation myocardial infarction has been updated: - To achieve these goals, the creation of networks including EMS, non PCI - Primary PCI (PPCI) is the preferred capable hospitals and PCI hospitals reperfusion strategy provided it is is useful. performed in a timely manner by an experienced team. ♦♦ Recommendations for the use - A nearby hospital may be bypassed of beta-blockers are more restrict- by emergency medical services ed: there is no evidence for routine (EMS) provided PPCI can be achieved intravenous beta-blockers except in without too much delay. specific circumstances such as for the treatment of tachyarrhythmias. - The acceptable delay between start Otherwise, beta-blockers should be of fibrinolysis and first balloon infla- started in low doses only after the tion varies widely between about 45 patient is stabilised. and 180 minutes depending on inf- arct localisation, age of the patient, and duration of symptoms. ♦♦ Guidelines on the use of prophy- lactic anti-arrhythmics angiotensin, - ‘Rescue PCI’ should be undertaken converting enzyme (ACE) inhibitors/ if fibrinolysis fails. angiotensin receptor blockers (ARBs) and statins are unchanged. - The strategy of routine PCI imme- diately after fibrinolysis (‘facilitated PCI’) is discouraged. Paediatric life support - Patients with successful fibrinolysis but not in a PCI-capable hospital Major changes in these new guidelines should be transferred for angiog- for paediatric life support include: raphy and eventual PCI, performed optimally 6 – 24 hours after fibri- ♦♦ Recognition of cardiac arrest - nolysis (the ‘pharmaco-invasive’ Healthcare providers cannot reliably approach). determine the presence or absence of a pulse in less than 10 seconds in
  • 15. 15 infants or children. Healthcare provid- minimise no-flow time. Compress ers should look for signs of life and if the chest to at least 1/3 of the ante- they are confident in the technique, rior-posterior chest diameter in all they may add pulse palpation for children (i.e., approximately 4 cm in diagnosing cardiac arrest and decide infants and approximately 5 cm in chil- whether they should begin chest com- dren). Subsequent complete release is pressions or not. The decision to begin emphasised. For both infants and chil- CPR must be taken in less than 10 dren, the compression rate should be seconds. According to the child’s age, at least 100 but not greater than 120 carotid (children), brachial (infants) or min-1. The compression technique for femoral pulse (children and infants) infants includes two-finger compres- checks may be used. sion for single rescuers and the two- thumb encircling technique for two or more rescuers. For older children, ♦♦ The compression ventilation (CV) a one- or two-hand technique can be ratio used for children should be based used, according to rescuer preference. on whether one, or more than one rescuer is present. Lay rescuers, who usually learn only single-rescuer tech- ♦♦ Automated external defibrillators niques, should be taught to use a ratio (AEDs) are safe and successful when of 30 compressions to 2 ventilations, used in children older than one year which is the same as the adult guide- of age. Purpose-made paediatric pads lines and enables anyone trained in or software attenuate the output of BLS to resuscitate children with mini- the machine to 50–75 J and these are mal additional information. Rescuers recommended for children aged 1-8 with a duty to respond should learn years. If an attenuated shock or a man- and use a 15:2 CV ratio; however, they ually adjustable machine is not avail- can use the 30:2 ratio if they are alone, able, an unmodified adult AED may particularly if they are not achieving be used in children older than 1 year. an adequate number of compressions. There are case reports of successful Ventilation remains a very important use of AEDs in children aged less than component of CPR in asphyxial arrests. 1 year; in the rare case of a shockable Rescuers who are unable or unwilling rhythm occurring in a child less than to provide mouth-to-mouth ventila- 1 year, it is reasonable to use an AED tion should be encouraged to perform (preferably with dose attenuator). at least compression-only CPR. ♦♦ To reduce the no flow time, when ♦♦ The emphasis is on achieving using a manual defibrillator, chest quality compressions of an adequate compressions are continued while depth with minimal interruptions to applying and charging the paddles or
  • 16. 16 Paediatric Basic Life Support Health professionals with a duty to respond UNRESPONSIVE? Shout for help Open airway NOT BREATHING NORMALLY? 5 rescue breaths NO SIGNS OF LIFE? 15 chest compressions 2 rescue breaths 15 compressions Call cardiac arrest team or Paediatric ALS team
  • 17. 17 Paediatric Advanced Life Support Unresponsive? Not breathing or only occasional gasps CPR (5 initial breaths then 15:2) Call Resuscitation Attach defibrillator/monitor Team Minimise interruptions (1 min CPR first, if alone) Assess rhythm Shockable Non-shockable (VF/Pulseless VT) (PEA/Asystole) Return of 1 Shock 4 J/Kg spontaneous circulation Immediately resume: Immediate post cardiac Immediately resume: CPR for 2 min arrest treatment CPR for 2 min Minimise interruptions • Use ABCDE approach Minimise interruptions • Controlled oxygenation and ventilation • Investigations • Treat precipitating cause • Temperature control • Therapeutic hypothermia? During CPR Reversible causes • Hypoxia • Ensure high-quality CPR: rate, depth, recoil • Plan actions before interrupting CPR • Hypovolaemia • Give oxygen • Hypo-/hyperkalaemia/metabolic • Vascular access (intravenous, intraosseous) • Hypothermia • Give adrenaline every 3-5 min • Consider advanced airway and capnography • Tension pneumothorax • Continuous chevvst compressions when advanced airway • Toxins in place • Tamponade - cardiac • Correct reversible causes • Thromboembolism
  • 18. 18 Newborn Life Support At all stages ask: Do you need HELP? Dry the baby Birth Remove any wet towels and cover Start the clock or note the time Assess (tone), 30 sec breathing and heart rate If gasping or not breathing Open the airway Give 5 inflation breaths Consider SpO2 monitoring 60 sec Re-assess If no increase in heart rate Look for chest movement Acceptable* If chest not moving pre-ductal SpO2 Recheck head position Consider two-person airway control 2 min : 60% or other airway manoeuvres 3 min : 70% Repeat inflation breaths 4 min : 80% Consider SpO2 monitoring 5 min : 85% Look for a response 10 min : 90% If no increase in heart rate Look for chest movement When the chest is moving If the heart rate is not detectable or slow (< 60) Start chest compressions 3 compressions to each breath Reassess heart rate every 30 seconds If the heart rate is not detectable or slow (< 60) Consider venous access and drugs
  • 19. 19 self-adhesive pads (if the size of the ♦♦ Implementation of a rapid child’s chest allows this). Chest com- response system in a paediatric in- pressions are paused briefly once the patient setting may reduce rates of defibrillator is charged to deliver the cardiac and respiratory arrest and in- shock. For simplicity and consistency hospital mortality. with adult BLS and ALS guidance, a single-shock strategy using a non- escalating dose of 4 J kg-1 (preferably ♦♦ New topics in the 2010 guidelines biphasic, but monophasic is accepta- include channelopathies and several ble) is recommended for defibrillation new special circumstances: trauma, in children. single ventricle pre and post 1st stage repair, post Fontan circulation, and pulmonary hypertension. ♦♦ Cuffed tracheal tubes can be used safely in infants and young children. The size should be selected by apply- Resuscitation of babies at ing a validated formula. birth The following are the main changes that ♦♦ The safety and value of using cricoid have been made to the guidelines for re- pressure during tracheal intubation is suscitation at birth in 2010: not clear. Therefore, the application of cricoid pressure should be modified or ♦♦ For uncompromised babies, a discontinued if it impedes ventilation delay in cord clamping of at least one or the speed or ease of intubation. minute from the complete delivery of the infant, is now recommended. As yet there is insufficient evidence to ♦♦ Monitoring exhaled carbon diox- recommend an appropriate time for ide (CO2), ideally by capnography, is clamping the cord in babies who are helpful to confirm correct tracheal severely compromised at birth. tube position and recommended dur- ing CPR to help assess and optimise its quality. ♦♦ For term infants, air should be used for resuscitation at birth. If, despite effective ventilation, oxygenation (ide- ♦♦ Once spontaneous circulation is ally guided by oximetry) remains unac- restored, inspired oxygen should be ceptable, use of a higher concentration titrated to limit the risk of hyperoxa- of oxygen should be considered. emia.
  • 20. 20 ♦♦ Preterm babies less than 32 weeks start mask ventilation, particularly if gestation may not reach the same there is persistent bradycardia. transcutaneous oxygen saturations in air as those achieved by term babies. Therefore blended oxygen and air ♦♦ If adrenaline is given then the should be given judiciously and its use intravenous route is recommended guided by pulse oximetry. If a blend using a dose of 10-30 microgram kg-1. of oxygen and air is not available use If the tracheal route is used, it is likely what is available. that a dose of at least 50-100 micro- gram kg-1 will be needed to achieve a similar effect to 10 microgram kg-1 ♦♦ Preterm babies of less than 28 intravenously. weeks gestation should be completely covered in a food-grade plastic wrap or bag up to their necks, without drying, ♦♦ Detection of exhaled carbon diox- immediately after birth. They should ide in addition to clinical assessment then be nursed under a radiant heater is recommended as the most reliable and stabilised. They should remain method to confirm placement of a tra- wrapped until their temperature has cheal tube in neonates with spontane- been checked after admission. For ous circulation. these infants delivery room tempera- tures should be at least 26°C. ♦♦ Newly born infants born at term or near-term with evolving moderate to ♦♦ The recommended compression: severe hypoxic – ischaemic encepha- ventilation ratio for CPR remains at 3:1 lopathy should, where possible, be for newborn resuscitation. treated with therapeutic hypother- mia. This does not affect immediate resuscitation but is important for post- ♦♦ Attempts to aspirate meconium resuscitation care. from the nose and mouth of the unborn baby, while the head is still on the perineum, are not recommended. If presented with a floppy, apnoeic baby born through meconium it is rea- sonable to rapidly inspect the orophar- ynx to remove potential obstructions. If appropriate expertise is available, tracheal intubation and suction may be useful. However, if attempted intu- bation is prolonged or unsuccessful,
  • 21. 21 Principles of education in ♦♦ Basic and advanced life support resuscitation knowledge and skills deteriorate in as little as three to six months. The use The key issues identified by the Educa- of frequent assessments will identify tion, Implementation and Teams (EIT) those individuals who require refresh- task force of the International Liaison Committee on Resuscitation (ILCOR) er training to help maintain their during the Guidelines 2010 evidence knowledge and skills. evaluation process are: ♦♦ CPR prompt or feedback devices ♦♦ Educational interventions should improve CPR skill acquisition and be evaluated to ensure that they retention and should be considered reliably achieve the learning objec- during CPR training for laypeople and tives. The aim is to ensure that learn- healthcare professionals. ers acquire and retain the skills and knowledge that will enable them to act correctly in actual cardiac arrests ♦♦ An increased emphasis on non- and improve patient outcomes. technical skills (NTS) such as leader- ship, teamwork, task management and structured communication will ♦♦ Short video/computer self-instruc- help improve the performance of CPR tion courses, with minimal or no and patient care. instructor coaching, combined with hands-on practice can be considered as an effective alternative to instruc- ♦♦ Team briefings to plan for resusci- tor-led basic life support (CPR and tation attempts, and debriefings based AED) courses. on performance during simulated or actual resuscitation attempts should be used to help improve resuscitation ♦♦ Ideally all citizens should be trained team and individual performance. in standard CPR that includes com- pressions and ventilations. There are circumstances however where train- ♦♦ Research about the impact of ing in compression-only CPR is appro- resuscitation training on actual patient priate (e.g., opportunistic training outcomes is limited. Although manikin with very limited time). Those trained studies are useful, researchers should in compression-only CPR should be be encouraged to study and report the encouraged to learn standard CPR. impact of educational interventions on actual patient outcomes.
  • 22. 22 Edited by Jerry Nolan Authors Jerry P. Nolan Charles Deakin Jasmeet Soar Rudolph W. Koster David A. Zideman Jonathan Wyllie Dominique Biarent Bernd Böttiger Leo L. Bossaert on behalf of the ERC Guidelines Writing Group Acknowledgements: The ERC staff members Annelies Pické, Christophe Bostyn, Jeroen Janssens, Hilary Phelan and Bart Vissers for their administrative support. Het Geel Punt bvba, Melkouwen 42a, 2590 Berlaar, Belgium (hgp@hetgeelpunt.be) for creating the algorithms and Griet Demesmaeker (grietdemesmaeker@gmail.com) for the cover design.
  • 23. 23 Become a member of the ERC You can choose between * Full membership on paper and electronic * Full membership electronic version only Full members on paper and electronic (€ 140 for 12 months) enjoy: - a subscription to Resuscitation, the official Journal of the ERC - online access to Resuscitation (including all previous issues) - reduction in the ERC-shop - special registration rates at ERC congresses Full members electronic version only (€ 115 for 12 months) enjoy: - online access to Resuscitation (including all previous issues) - reduction in the ERC-shop - special registration rates at ERC congresses These benefits add to all the benefits you experienced as a web member: - participate in ERC forums - download items from libraries - stay updated with our ERC News Letter IMPORTANT ERC currently offers combined membership possibilities with a number of organisations, with an additional discount: Belgian Resuscitation Council, Norwegian Resuscitation Council, Resuscitation Council UK. If you are already a member of one of these organisations, please contact their secretariat for additional information about combined membership possibilities.