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ELIXIR and Impact

19 November 2013

Jackie Hunter
Chief Executive, BBSRC
Grand challenges
• the growing demands for food, water and energy
• an ageing population

• environmental degradation
• th...
Three major strategic science priorities

Bioenergy and
Industrial biotechnology

Food Security

(Grand Challenges)

Basic...
BBSRC priorities and supporting requirements
• Food Security/Agriculture

Sustainable
infrastructure

• Combating Infectio...
ELIXIR broad impacts
– Underpins access to information from other
investments
– Promotes innovation & collaboration
– Enha...
Where can bioinformatics have most
impact?
• Bridging the genotype to phenotype gap
–
–
–
–

Plants
Animals
Man
In healthy...
Impact for new medicines development
• Addressing the variational range of European human
genome data
• Enabling better pr...
Model of the human metabolic
network
• Multi national collaboration provided results only made
possible by a big data appr...
Goals of US report – “Unleashing a Decade of
Innovation in Plant Science”
•

Increase the ability to predict plant traits
...
Virtual Organisms and Crop Science
•

Combining e-organisms (virtual
leaf, root, seed etc.) with
genome & phenome data

•
...
Working together will maximise
global impact
ELIXIR and impact
• Real opportunity to bridge genotype to
phenotype gap
• Create new communities
• Build skills and capab...
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ELIXIR and Impact presentation given by Jackie Hunter, Chief Executive, BBSRC, at ELIXIR Launch event 18th December 2013

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ELIXIR and Impact presentation given by Jackie Hunter, Chief Executive, BBSRC, at ELIXIR Launch event 18th December 2013

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Transcript of "ELIXIR and Impact presentation given by Jackie Hunter, Chief Executive, BBSRC, at ELIXIR Launch event 18th December 2013"

  1. 1. ELIXIR and Impact 19 November 2013 Jackie Hunter Chief Executive, BBSRC
  2. 2. Grand challenges • the growing demands for food, water and energy • an ageing population • environmental degradation • the loss of biodiversity • the need to respond rapidly to emerging global threats such as pandemics and bioterrorism
  3. 3. Three major strategic science priorities Bioenergy and Industrial biotechnology Food Security (Grand Challenges) Basic Bioscience Underpinning Health Three crucial enabling themes KE, Innovation and Skills Exploiting New Ways of Working Partnerships 1.Thinkstock 2011. 2. IBERS. 3.Thinkstock 2011. 4. BBSRC. 5.Thinkstock 2011 6.Thinkstock 2011
  4. 4. BBSRC priorities and supporting requirements • Food Security/Agriculture Sustainable infrastructure • Combating Infectious Diseases Central delivery to ensure excellence in life science data management • Translation to Clinical Research • Enabling Technology Development • Enhancing Links with the industry sectors Increased competence and size of user community ELIXIR can support all of this
  5. 5. ELIXIR broad impacts – Underpins access to information from other investments – Promotes innovation & collaboration – Enhances training & dissemination – Increases research productivity & performance – Improved integration of life science data & services throughout Europe – Enabling the management of data in a seamless way
  6. 6. Where can bioinformatics have most impact? • Bridging the genotype to phenotype gap – – – – Plants Animals Man In healthy organisms and disease • Better target validation – For new plant varieties – For new medicines • Tracking biodiversity to sustain natural resources
  7. 7. Impact for new medicines development • Addressing the variational range of European human genome data • Enabling better prediction of drug actions & drug combinations on individual patients • Ultimately creating a seamless continuum from genomic data through preclinical data to electronic health records Credit: thinkstock
  8. 8. Model of the human metabolic network • Multi national collaboration provided results only made possible by a big data approach • Model provides a framework to understand better the relationship between an individual’s genetic make-up and his/her lifestyle – step closer to ‘personalised medicine’ http://humanmetabolism.org Credit: istockphoto
  9. 9. Goals of US report – “Unleashing a Decade of Innovation in Plant Science” • Increase the ability to predict plant traits from plant genomes in diverse environments • Assemble plant traits in different ways to solve problems • Discover, catalogue, and utilise plantderived chemicals • Enhance the ability to find answers in a torrent of data • Create a T-training environment for plant science doctoral students
  10. 10. Virtual Organisms and Crop Science • Combining e-organisms (virtual leaf, root, seed etc.) with genome & phenome data • Building models using local and distributed high-performance computing infrastructure • Enabled by advances in image quality at both the micro and macro level and improvements in image analysis Credit: University of Nottingham
  11. 11. Working together will maximise global impact
  12. 12. ELIXIR and impact • Real opportunity to bridge genotype to phenotype gap • Create new communities • Build skills and capabilities • Enhance EU competitiveness • Promote problem led large scale integrative bioscience
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