Results of breast-conserving surgery in cancer patient
Kamila RakhimovaAdvisor:M.N.Shepet’ko,MD PhD,Associate ProfessorResults of breast-conservingsurgery in cancer patient
TopicalityMastectomy-all of the breast tissue isremoved, sometimesalong with other nearbytissues and lymphaticnodesSegmental resection-removes a part of the affectedbreast (less traumatic, keepsaesthetic appearance, betterquality of life)Surgery results
MissionCompare effectiveness of segmental resection versus Maddenmastectomy in breast cancer (BC) women.
Materials and methods:Study 136 patients historyHospital Minsk Clinical Oncology DispensaryDuration Years 2009-2013BeginningEndDate of surgeryMarch, 2013Assessment Disease stage, surgery tactic, adjuvant therapy, incidence ofrecurrence, metastasis, mortality.
Results and discussionsStatistics matching in clinical groupsGroups Segmental resection MastectomyTotal number 97 39Age 56±20 (36÷83) 59±16 (37÷75)Radio Therapy (RT) in thebreast location97 39RT in axillar ( under arm)zone32 39
Results and discussions IIChemotherapy Segmental resection MastectomyTotal number of patient 84 (86,6%) 38 (97,4%)3 courses 5 (5,2%) 0 (0 %)4 courses 23 (23,7%) 7 (17,9 %)5 courses 19 (19,6%) 6 (15,4%)6 courses 36 (37,1%) 23 (59%)Additional courses 1 2Statistics matching in clinical groups
Results and discussions IIIBC stage Complications Segmental resection97 patientsMadden mastectomy39 patientsNumber ofpatients% Number ofpatients%I A-B Recurrence in the scar 2 4,1 - -Metastasis 3 6,2 - -Mortality 0 0 - -II A-B Recurrence in the scar 1 4 1 2,6Metastasis 6 12 3 7,7Mortality* 1 2,8 0 0III A-С Recurrence in the scar * 2 20 - -Metastasis* 5 38,5 - -Mortality* 2 15,4 - -*- statistic significance ≤0,05рIncidence of complications in BC surgery patients
Results and discussions IVType of surgery Total number ofsurvivals, with nometastasis andrecurrence in %Survival withno recurrencein %Survival with nometastasis in %Segmentalresection*77,3 94,8 85,6MaddenMastectomy*89,7 97,4 92,3*- statistic significance p≤0,05
Conclusions:• Madden mastectomy, assuming all other conditions equal,revealed less recurrence, metastasis and mortality.• While the research got in stage I A-B only the segmentalresection performed the results cannot be statisticallyconsidered.• Survivals number after Madden mastectomy in theconditions of this study with no metastasis and recurrenceprove maximum radicalism justified.