Antimicrobal Resistance

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Antimicrobal Resistance

  1. 1. The antimicrobialresistance { Growing threat and the options for action V. Harutyunyan M.D.
  2. 2. Antimicrobial Resistance: a global issue Cause of considerable mortality Greatly increases care costs and productivity losses Impediment to control of infectious diseases Jeopardizes healthcare gains for individuals and society Treat to international travel and trade Dwindling options for treatment of the infectious diseases
  3. 3. Mortality & Cost 25,000 deaths/year in hospitals Europe 63,000 year in USA in outpatients Mortality due to AMR in community settings Mortality in developing countries 1.5 billion € for the EU region 25-35 billion USD: total additional costs of the US hospitals Costs for the individuals, families and societies hard to quantify
  4. 4. Cost of AMRContaining antimicrobial resistance. Geneva, World Health Organization, 2005, WHO Policy Perspectives on Medicines, No.10 (http://whqlibdoc.who.int/hq/2005/WHO_PSM_ 2005.1.pdf, accessed 9 January 2012).
  5. 5. Treat to global health 290,000 new multidrug resistance (MDR) TB cases in 2010 Malaria: Emergence of Artemisinin resistance HIV: 10%-20% of the resistance rates to anti HIV regimens in the US and Europe Increasing spread of common bacterial infections resistant to antibiotics in health care settings, communities and across borders
  6. 6. Dwindling treatment optionsThe evolving threat of antimicrobial resistance: options for action. WHO 2012
  7. 7. WHO global response WHO Global Strategy for Containment of AMR (2001) WHO Regional Committee Resolutions (e.g. AFRO, PAHO, SEARO) World Health Assembly Resolutions WHD 2011 Six Point Policy Package
  8. 8. WHO actions Promote the sharing of information about, understanding of resistance and coordination of actions to control the spread of AMR Raise awareness of the problems posed by antimicrobial resistance Build consensus on the methods of AMR surveillance and control Provide strategic and technical guidance on interventions to contain resistance Assist Member States to implement these interventions Stimulate innovation and research to improve understanding of antimicrobial resistance and to encourage research and development of new drugs, vaccines and diagnostics

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