Nir Hus Absite review q5b

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Slides with topics that are covered and were tested in the recent Absite exams.
Nir Hus MD., PhD.
http://www.nirhus.com

Published in: Health & Medicine, Technology
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Nir Hus Absite review q5b

  1. 1. Absite topics 13-15Nir Hus Nir Hus
  2. 2.   The Proper time for prophylactic dosing is:A.  1 hr. preopB.  With induction of anasthesiaC.  At the time of skin incisionD.  2 hrs preop Nir Hus
  3. 3. Q13 – Infection rate of wounds Nir Hus
  4. 4. ~2% 3%-5% 5%-10% >30%Nir Hus
  5. 5. Q14 - Drug dose adjust forHemodialysis for Low MolecularWeight Heparin  For Lovenox, no dose adjustment for H.D.  For CrCl < 30  DVT proph. 30 mg SQ daily not 40.  Normal halflife 4.5-7 hrs. Nir Hus
  6. 6. Q15 - Staphylococcus epidermis  Eradication of Staphylococcus epidermis is difficult to achieve due to: A.  Secretion of exotosins B.  Production of exoslime C.  Release of endotoxin D.  Rapid growth rate Nir Hus
  7. 7. Staphylococcus epidermis  Staphylococcus epidermis exoslime is a polysaccharide composed of glycosaminoglycans which allows for strong intercellular adhesion between bacterial cells and the formation of biofilms.  The ability to form biofilms allows S. epidermidis to cause resistant infections particularly when foreign object are present.  This is due to inability of antibiotics to penetrate the mucopolysaccharide of the biofilm.  The ica operon has been shown to control the production of slime . The ica genes can be tested for as a virulence marker. Nir Hus
  8. 8. Q - Respirator Quotient in sepsis& vent support  Respirator Quotient (RQ) is the ratio of VCO2 (production) to VO2 (consumption).  A characteristic RQ exists for each fuel being metabolized.  Fat: 0.7  Protein: 0.8  Glucose : 1.0  If RQ is greater than 1, strong indicator of overfeeding. Nir Hus

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