Brian D Strahl, Faculty Director of the UNC Peptide Synthesis Core Facility

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The mission of the High-throughput Peptide Synthesis and Array Facility is to provide researchers with high quality consultation and peptide synthesis services including production, purification, and characterization of polypeptides and custom designed peptide arrays.

We are reasonably priced, fast and offer the highest possible quality and standards. We will work with you to help design the right peptide for your needs.

Synthetic peptides including peptides containing nonstandard (modified or unnatural) amino acids, e.g. acetylated Lys, methylated Lys or Arg, phosphorylated Ser Thr or Tyr residues, fluorescent tags, biotinylation, D-amino acids, unnatural amino acids (e.g. 6-Cl-Trp), stable isotopes (2H, 13C, 15N) and PEG linkers/spacers. Synthesis of peptide libraries (~100 peptides). Preparation of peptide microarrays up to 4000 spots per slide. Synthesis of Multiple Antigenic Peptides (MAPs) for antibody production.

Director: Krzysztof Krajewski, PhD; Faculty Director: Brian Strahl, PhD
E-mail: peptides@unc.edu

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Brian D Strahl, Faculty Director of the UNC Peptide Synthesis Core Facility

  1. 1. HTPSA Core Facility Peptide Synthesis FacilityFast synthesis of high quality peptides, including peptides containing singleto multiple post-translational modifications, fluorescent tags, biotin andunnatural amino acids, for multiple research applications including:- antibody production- ITC, FP, crystallography and NMR studies- protein interaction studies O OH- peptide arrays O O O O- biological and enzyme assays HN NH2- peptide ligation HOModifications we specialize in include: acetylation, methylation,phosphorylation, biotinylation, lipopeptides, fluorescent tags, stapledpeptides, and peptide thioesters for native chemical ligation.We are reasonably priced, fast and offer the highest possible quality andstandards. We will work with you to help design the right peptide for yourneeds.To learn more, please visit www.med.unc.edu/biochem/unc-peptidesor contact us at peptides@unc.eduSeveral recent references of our work:Nat. Struct. Mol. Biol. (2012) 19, 1155; Curr. Biol. (2011) 21; 53;Methods Enzymol. (2012) 512, 107-35; Genome Res. (2012) 22, 1646.High-Throughput Peptide Synthesis and Arrays Core Facility, UNC Chapel Hill E-mail: peptides@unc.edu Phone: 919-843-3935

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