Significance of apoptosis

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Significance of apoptosis

  1. 1. CELLULAR CHANGES DURING APOPTOSIS .
  2. 2. . <ul><li>CONDENSATION OF CHROMATIN </li></ul><ul><li>FRAGMENTATION OF CHROMOSOMAL DNA </li></ul><ul><li>SHRINKAGE AND FRAGMENTATION OF NUCLEOUS </li></ul><ul><li>LOSS OF CYTOPLASM </li></ul><ul><li>BREAKDOWN OF MITOCHONDRIA </li></ul><ul><li>E R FUSES WITH PLASMA MEMBRANE </li></ul><ul><li>CELL DETACHES FROM NEIGHBOURING CELLS APOPTOTIC BODIES ARE FORMED </li></ul><ul><li>NEAR BY CELLS ENGULF AND DESTROY THE APOPTOTIC BODIES </li></ul>
  3. 3. SIGNIFICANCE OF APOPTOSIS .
  4. 4. . <ul><li>MAINTANANCE OF NORMAL TISSUE DURING DEVELOPMENT </li></ul><ul><li>HELP IN DISPOSAL OF CELLS WHICH ARE DAMAGED,UNWANTED AND DANGEROUS </li></ul><ul><li>AVOIDS AUTOIMMUNITY BY ELEMINATING SELF REACTIVE T CELL </li></ul><ul><li>ELEMINATION OF VIRUS INFECTED CELLS </li></ul><ul><li>DEFENCE AGAINST INFECTIONS AND HARMFUL CHEMICALS </li></ul><ul><li>PREVENT TUMOUR FORMATION </li></ul><ul><li>IT MAINTAINS CONSTANT BALANCE BETWEEN CELL DIVISION AND CELL DEATH </li></ul>
  5. 5. THANKS .

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