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Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
Comprehensive Report on The Cannabis Extract Movement
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Comprehensive Report on The Cannabis Extract Movement

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Comprehensive Report on The Cannabis Extract Movement

Comprehensive Report on The Cannabis Extract Movement

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  • 1. 1 The Comprehensive Report on the Cannabis Extract Movement and the Use of Cannabis Extracts to Treat Diseases Author: Justin Kander Consulting Editor: Nicholas Davey 4th Edition June 2014 Originally Published October 2013
  • 2. 2 Abstract This report aims to be a comprehensive analysisofthe cannabis extract movement,a collectionof patients,caregivers,doctors, dispensaries,corporations,and activists that advocate for the use of cannabis extract medicine to treat seriousdiseasessuchas cancers, heart disease,diabetes, rheumatoidarthritis, epilepsy, multiple sclerosis,Crohn’s,andotherdisorders. In aggregate, the movementhas demonstratedbeyondreasonable doubt that cannabis extracts can eliminate various typesof cancers in humans, and can control diseasesthat traditional pharmaceuticalsare ineffective against. The ultimate goal of this report issimple – to initiate immediate trialsof cannabis extract medicine inhospice centers. Patients insuch centers have terminal diagnosesand nothingto lose by attemptinga treatment whichhas a very real chance of curing them. Moreover,cannabis extracts are completelynon-toxicandcarry no physiological risks. If proven through hospice trials that cannabis extracts can reliablyeliminate cancers,true clinical trials can beginto determine optimumcannabis extract treatment regimentsand the full extentof cannabinoid medicine’seffectiveness. This report integratesthe latestscientificresearchand experiential resultstomake a compellingcase that cannabis extracts are effective treatmentsfora wide variety ofdiseases. The strength of the arguments, whenanalyzedas a whole,is overwhelming. The report progressesas follows: 1. Overview of Supporting Science 2. History of Rick Simpson and Phoenix Tears 3. Individual Case Reports 4. Corporate and Dispensary Operations 5. Doctor and Team Operations 6. Concluding Discussion
  • 3. 3 1. Overview of Supporting Science While there are noactual clinical studiesoncannabisextractmedicineforthe treatmentof disease currentlyinexistence (althoughsome are scheduledtobeginsoon),there isanimmense bodyof scientificevidence demonstratingthatcannabinoidsare effectiveagainstvirtuallyanydisease. There is alsoa specificcase studyinthe journal CaseReportsin Oncology whichclearlydemonstratesthat cannabisextractscan eliminateleukemicblastcellsinahumanpatient. Most studies focusonthe effectsof individual cannabinoidsincellularandanimal models. Alone, these studies donotprove effectivenessinhumans.Inagreat manycases,cellularandanimal resultsdo not translate tohumansbecause of complex physiological differences. However,everycompoundthat worksfor humansstartsby workingat these smallerlevels. Furthermore,inthe contextof people actuallyusingconcentratedcannabinoidstoachieve curativeeffects,the scientificstudieshave farmore relevance. Substantial quantitiesof researchhave focusedoncannabinoidsandthe cellularmechanismsby whichtheyaffectvariouscancers. Suchmechanismsinclude inductionof apoptosis(programmedcell death),cell-cycle arrest, andinhibitionof angiogenesis(thegrowthof bloodvesselstotumors). However,severalstudieshave pointedoutthatotherprecise pathwaysare still undetermined, indicatingthe needtolearnmore abouthow cannabinoidswork. One of the firstpositive studieswascarriedoutatthe Medical College of Virginiain1974. The study,while intendedtoprove thatcannabisuse damagesthe immune system, actuallyfoundthat tetrahydrocannabinol slowedLewislungadenocarcinomaandleukemiagrowthina dose-dependent relationship(http://www.ncbi.nlm.nih.gov/pubmed?cmd=Retrieve&list_uids=1159836). The effectof THC on braincancer is well documentedbyDr.Manuel Guzmánand histeamof researchersinSpain. In1998, theypublishedastudydocumentingTHC’sabilitytoinduce apoptosisin gliomacells(http://www.ncbi.nlm.nih.gov/pubmed/9771884). In 2005, Guzmán’steam further identifiedthatTHCcoulddecrease productionof vascularendothelial growthfactorandmitigate activationof the relatedreceptorVEGFR-2,whichhelpedstopangiogenesis. Throughthismechanism, culturedgliomacellsandmouse gliomaswere reduced (http://cancerres.aacrjournals.org/content/64/16/5617.full). Additionally,one of Guzmán’sstudiesin 2003 showedactivationof cannabinoidreceptorswasassociatedwithapoptosisof skincancercells, while healthycellsremainedunaffected(http://www.jci.org/articles/view/16116). A 2006 Guzmánstudyon pancreaticcancer deliveredseveral interestingresults,mostnotably the observationsthatTHC inducedapoptosisinmultiple pancreaticcancercell linesandreducedtumor growthin twoanimal models(http://cancerres.aacrjournals.org/content/66/13/6748.full). Italsofound cancer cells expressedhigherlevelsof cannabinoidreceptorsthanhealthycells,possiblyindicatinga innate defensemechanismthe bodyhasagainstcancerouscells. Thatis,as a last resortagainstcancer, if the abnormal cellsthemselvespossessmore cannabinoidreceptors,theywouldbe more susceptible to the apoptosis-inducingeffectsof bothendoandphytocannabinoids. In thiscase,the role of the CB2 receptorwascritical,as blockingthe receptorpreventedTHC-inducedapoptosis;blockingthe synthesis of ceramide,aproapoptoticcompound,alsopreventedapoptoticeffects. A yetfurtherstudyby
  • 4. 4 Guzmán in2008 found gliomacell invasionisinhibitedbyTHC throughthe down-regulationof matrix metalloproteinase-2(http://cancerres.aacrjournals.org/content/68/6/1945.full). THC is particularlyeffective againstlungcancerboth in vitro and in vivo. A 2007 Harvard study showedthatTHC inhibitednonsmall celllungcancercell linesandthatTHC-treated,cancerousmice had 50% reductionsintumorweightandvolume,and60% reductionsinmacroscopiclesions (http://www.aacrmeetingabstracts.org/cgi/content/meeting_abstract/2007/1_Annual_Meeting/4749). A laterApril 2012 studyfoundthat cannabidiol,anothercannabinoidprovingtobe evenmore beneficial than THC, alsohad an anti-metastaticeffectonone of the same lungcancer cell lines,A549,as well as the linesH358 and H460 (http://www.ncbi.nlm.nih.gov/pubmed/22198381). The effectonprostate cancer isalso well documented. A September1999 studyfoundthatTHC couldinduce apoptosisinthe cancerousPC3cell line,andthese effectsoccurredindependently of cannabinoidreceptors(http://www.ncbi.nlm.nih.gov/pubmed/10570948). The receptor-independent phenomenaisdiscussedfurtherbelow. Additionally,asummarizingstudyonthe endocannabinoid systemandprostate cancer discussedthe potential role of the systeminmaintainingprostate homeostasis,aswell asthe abilityof several cannabinoidstoreduce prostate cancercell proliferation and migration(http://www.ncbi.nlm.nih.gov/pubmed/21912423). Researchhasshownthat cannabinoidsexertpositive benefitsatthe geneticlevel. A studyby Dr. SeanMcAllisterinNovember2007 showedthatcannabidiol coulddown-regulate Id-1gene expressioninaggressivebreastcancercells,limitingtheirmetastaticpotential (http://mct.aacrjournals.org/content/6/11/2921.long). A furtherstudyinAugust2011 clarifiedthe pathwaysbywhichId-1 expressionwasinhibited(http://www.ncbi.nlm.nih.gov/pubmed/20859676). A September2004 studyfrom the Departmentof Medical OncologyinLondonshowedthatTHCwas a potentinducerof apoptosisinmultiple leukemiccell linesatleastpartiallythroughchanginggene expressionlevels(http://bloodjournal.hematologylibrary.org/content/105/3/1214.full). A 2012 studyinthe British Journalof Pharmacologyexaminedcannabidiol’ssuccessfulcapability to inhibittumorangiogenesis(http://www.ncbi.nlm.nih.gov/pubmed/22624859). A 2005 study demonstrated cannabidiolinhibitsgliomacell migration (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1576089/). Moreover,itwas shownthatthese effects occurredindependentof cannabinoidreceptors,indicatingthatcannabinoidsinfluence physiological processesbeyondthe activationof receptors. Thissame cannabinoid-receptor-independentproperty was alsomentionedinthe 2004 Londonstudydiscussedabove,andina 2011 MolecularCancer Therapeuticsarticle aboutCBD inducingbreastcancercell death,the propertywasobservedyetagain (http://www.ncbi.nlm.nih.gov/pubmed/21566064). Pancreaticcancer,one of the mostfatal,isalso susceptibletothe apoptosis-inducingeffectsof cannabinoids (http://www.ncbi.nlm.nih.gov/pubmed/16500647). The previousstudy alsostates thatinsome cases, receptoractivationmayor may notbe critical toapoptosis-induction. AnotherstudyinFebruary2008 concludedthatcannabinoidsmaybe aneffective treatmentforinflammationandfibrosisinchronic pancreatitis(http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253501). An October2013 studyfoundthatCBD inhibitedcellproliferationof the U87-MG and T98G gliomacell linesanddecreasedexpressionof proteinsassociatedwithgrowth,invasion,and angiogenesis(http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0076918). A November2013 studyin InternationalJournalof Cancer testedthe effectsof CBDalone andin
  • 5. 5 combinationwithachemotherapeuticagentagainst multiple myeloma (http://www.ncbi.nlm.nih.gov/pubmed/24293211). CBD workedbyitself orinsynergywithbortezomib to stronglyinhibitgrowth,arrestcell cycle progression,andinduce cell deathinmultiple myelomacells. A 2010 studyin Urology showedthatCBD inducedapoptosisoccurredviathe regulationof calciuminflux throughthe TRPV2channel protein,atrans-membrane channel inhumanurothelial carcinomacells(http://www.ncbi.nlm.nih.gov/pubmed/20546877). The November2011 issue of AnticancerResearch featuredanarticle aboutCBD and the syntheticcannabinoid WIN-55,212’sabilities to induce apoptosisinprostate andcoloncancercellsthroughthe modulationof complexcell signaling (http://www.ncbi.nlm.nih.gov/pubmed/22110202). Cannabinoidreceptorsingeneral were implicatedinimprovingdisease-free survival of liver cancer patients. A November2006 studyfoundthat disease-free survival wasmuchbetterinpatients withhighexpressionlevelsof CB1and CB2 receptorsthanthose withlow-level expression (http://www.ncbi.nlm.nih.gov/pubmed/17074588). In2005, a Swedishresearchteamfoundthat activatingreceptorswithsyntheticcannabinoidsandendocannabinoidscoulddecreasethe viabilityof mantle cell lymphoma(http://www.ncbi.nlm.nih.gov/pubmed/16337199). An article in2010 by a Chinese researchteamdiscussedthe effectsof cannabinoidreceptoractivationonhepatomacells,and foundactivationinducedapoptosisandinhibitedproliferation (http://www.ncbi.nlm.nih.gov/pubmed/20368112). AlthoughTHCand CBD have receivedthe bulkof attentionwhenitcomestoresearch, other cannabinoidsalsopossessanti-cancereffects. A September2006 article analyzedthe effectsof several cannabinoidsonhumanbreastcarcinoma. Cannabidiol wasfoundtobe the mostpotentinhibitorof cancer cell growth,whereascannabigerol (CBG) andcannabichromene (CBC) were foundtobe effective as well (http://jpet.aspetjournals.org/content/318/3/1375.full). AnOctober2013 article in Anticancer Research foundthat six cannabinoids,includingcannabidiol,cannabigerol,cannabigevarin,andtheir acid forms,couldinhibitleukemiacells independently (http://www.ncbi.nlm.nih.gov/pubmed/24123005). However,whenthe cannabinoidswere combined, the anticancereffectwasevengreater,indicatingasynergisticeffect. Endocannabinoids,the cannabinoid-likemoleculesproducedwithinthe body,have apoptosis- inducingeffectsaswell. A February2006 studyin ExperimentalCell Research foundthat the endogenouscannabinoidanandamide inhibitedthe adhesionandmigrationof breastcancercells,and that the endocannabinoidsystemregulatessuchcancercell proliferation (http://www.ncbi.nlm.nih.gov/pubmed/16343481). A June 2003 studyin Prostateshowedanandamide inducedapoptosisinmultipleprostate cancercell lines,includingthe PC3line,whichhasproven susceptibletoTHC as well (http://www.ncbi.nlm.nih.gov/pubmed/12746841). Evenmetastaticgrowth was inhibited. Additionally,the ceramide theoryof apoptosiswasbolsteredfurther,withthe study concludingthe cytotoxicactionsof anandamide mayoccurthroughthe inductionof intracellular ceramide production. Endocannabinoidswere alsoshowntoinhibitcolorectal cancercell proliferation ina January2008 study(http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755791). An October2011 studydemonstratedthatanandamideandtwootherendocannabinoidscould reduce the viabilityof mice neuroblastomacells (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203169). Priorto this,a 2000 studyin The Journalof
  • 6. 6 Biological Chemistry showedthatanandamide inducedapoptosisinhumanneuroblastomaand lymphomacells(http://www.jbc.org/content/275/41/31938.full). While there are farmore studiesoncannabinoidsandcancer,the above isa fairoverview. More antitumorstudieshave beenelegantlysummarizedandpresentedonthe National Cancer Institute’swebsiteat http://www.cancer.gov/cancertopics/pdq/cam/cannabis/healthprofessional/page4. Before movingontostudiesregardingotherseriousdiseases,itisimportanttoexaminethe endocannabinoidsystem’s(ECS) organism-level functions. Ashasbeensuggestedthroughthe cancer- relatedstudiesalone,the importanceof the ECSis critical. All typesof cannabinoids –phyto,endo,and evensynthetic,caninduce apoptosisincancercellsthroughawide varietyof mechanisms. The factthat cancer cellsexpresshigherlevelsof cannabinoidreceptorsthannormal cellsisalsoremarkably intriguinginlightof endocannabinoidanticancerproperties. Evenwithoutphytocannabinoids,the body has an excellentdefense systemagainstabnormal cells. Whencellsbecome malignant,theydevelop more receptorsandbecome more susceptibleendocannabinoids,andthuscanbe efficientlyeliminated. However,itappearsthatdue to nutritional and/orenvironmental factors,the capabilitiesof endocannabinoidsare oftennotenough,andphytocannabinoidsupplementationisnecessarytorestore balance. Several studieshave pointedtothe homeostatic-maintenance propertiesof the ECS. Homeostasisisthe restingconditionof healthof anorganism, includingbutnotlimitedtofactorssuch as hydration,energy,temperature,andmaintenance of properenzyme,hormone,andneurotransmitter levels. Maintaininghomeostasisisof paramountimportance,forif itistoostronglyimpaired,an organismwill die. Researchisbeginningtoindicate thatthe ECSis the primaryregulatorof homeostasis inthe body. If thisis the case,thenthe astoundingmedicinalpropertiesof phytocannabinoidsbecome much more understandable. All diseaseultimately stemsfromanimbalance of some kind. Although thisstatementisanimmense simplificationof the complexoriginsandmechanismsof variousdiseases, it still accuratelydescribesthe fundamentalnature of disease –imbalance,irregularity,abnormality. Theoretically,phytocannabinoidsfunctioningwithinthe ECScouldrestore homeostaticbalance andthus eliminatebodilydisease. Giventhe factthatin practice humansare usingconcentrated phytocannabinoidstosuccessfullytreat amultitude of diseases, thesehigh-level theoriesonthe ECS mustbe givenmore weight. Asadditional researchisconducted,the exactmechanismsbywhich cannabinoidsheal individualdiseasesandmaintainorganism-wide homeostasiswilldoubtlessbe revealed. Dr. RobertMelamede, formerCEOand Presidentof CannabisScience andAssociate Professorat Universityof ColoradoColoradoSprings,haspioneeredsignificantresearchonthe ECS. Dr. Melamede’s paperon endocannabinoidsasglobal homeostaticregulatorsdiscussesthe remarkablydiverse methods of ECS function(http://necsi.edu/events/iccs6/viewpaper.php?id=70). Otherresearchhasconfirmed the regulatorypropertiesof the ECS. A January 2005 studydiscussedhow the ECSappearedearlyin evolutionandmodulatescritical functionslike the autonomicnervoussystem, immune systemand microcirculationin all vertebrates (http://alcalc.oxfordjournals.org/content/40/1/2.short). A 2006 study inInternationalJournalof Obesity spoke of the ECSas a regulatorof energyhomeostasis,participatingin functionslike fatmetabolismandappetite (http://www.nature.com/ijo/journal/v30/n1s/full/0803276a.html).
  • 7. 7 A June 2010 studyin Pharmacology Biochemistry and Behavior elaboratedonveryintriguing ideas,includingthe role of the ECSin regulatingvariousaspectsof embryological developmentand homeostasis(http://www.sciencedirect.com/science/article/pii/S0091305710000924). The study primarilysuggestedthatthere were aspectsof the ECSwhichbecame dysfunctional inobese people. Since CB1 receptorswere knowntobe involvedinappetite,CB1antagonistdrugswere developedto blockthe activationof the receptorsandthus decrease appetite. While thiswaspartiallyeffective, numerousside effectsoccurredandthe use of such antagonistswasdiscontinued. Giventhe widespreadfunctionof cannabinoidreceptorsbeyondappetite,the verypoorresultsof CB1blockade are notsurprising. The studyconcludesbysayingalternativecannabinoid-basedtherapiesshouldbe openforconsideration. Furtherdiscussionof endocannabinoid systemregulatorymechanismsis examinedinDr.WilliamCourtney’ssegmentof the Doctor and Team Operations section. The ubiquitousnature of the endocannabinoidsystemisdemonstratedbythe fact that it is somehowinvolvedinagreat array of diseases. Althoughthe purposeof thisreportisnotto examine everyscientificarticle oncannabinoids,itisimportanttounderstandthe profoundlyversatile,positive, and diverse benefits of cannabinoids. A January2008 article in Neuropharmacologynotedhow CBD-treated,non-obese diabetes- prone female mice hadonlya32% incidence of diabetesdiagnosis,comparedto100% in the untreated group(http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270485/). The studyalsoreferencedanearlier workwhere cannabidiol loweredthe incidence of diabetesinmice. A June 2007 studyproposedthat the ECS regulatesglucose homeostasisthroughcoordinatedactionsof CB1and CB2 receptors, whilealso showingactivationof CB2receptorsimprovedglucose tolerance (http://www.sciencedirect.com/science/article/pii/S001429990700249X). Intriguingly,the study showedactivatingCB2receptorsresultsinsimilaractionsasblockingCB1receptors,demonstratingthe integral relationshipbetweenbothreceptortypes. A 2010 studyinthe Journalof theAmerican College of Cardiology,partiallyauthoredbyDr. Raphael Mechoulam(the firsttoisolate tetrahydrocannabinol),concludedthatcannabidiol mayhave great therapeuticpotential fordiabetes,throughthe attenuationof oxidative/nitrative stress, inflammation,cell death,andfibrosis(http://www.natap.org/2010/newsUpdates/marijuana.pdf). Benefitforcardiovasculardisorderswasalsosuggested. Infact,a previous2002 studyin Bulletin of ExperimentalBiology and Medicine linkedthe activationof cannabinoidreceptorswithcardioprotective effects,demonstratingthatcannabinoidscanpreventthe deathof healthycellsduringaheartattack (http://www.ncbi.nlm.nih.gov/pubmed?Db=pubmed&Cmd=Retrieve&list_uids=12428278). Also,a March 2006 studyfoundthat the ECS, throughactivationof CB2 receptors,wasimportantforprotection frommyocardial ischemia,aconditionresultingindecreasedbloodflow tothe heart (http://www.ncbi.nlm.nih.gov/pubmed/16618028). Cannabinoidsalsoexertsignificantliverprotectiveeffects. A December2003 studyin Molecular Pharmacology showedthatasyntheticcannabinoidcouldinhibitinflammatoryliverdamage inmice, partiallythroughpromotingthe earlyexpressionof protective genes (http://molpharm.aspetjournals.org/content/64/6/1334.full). A later2008 studyin the same journal concludedthatTHC couldinhibithepatitisinmice byreducinglivertissue injury (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828293/). The studyalsofoundTHC suppressed inflammationandsignificantlyincreasedspecializedliverregulatorycells.
  • 8. 8 HIV is one of the mostdestructive virusesfacinghumanitytoday,andcannabismaybe the solution. Patientshave continuouslyreported thatcannabisuse improvessymptoms,including appetite,muscle pain,nausea,anxiety,nerve pain,anddepression (http://www.ncbi.nlm.nih.gov/pubmed/15857739). Evidence alsosuggeststhatcannabinoidscan inhibitthe HIV virusdirectly. Much insightcomesfromresearchintosimianimmunodeficiencyvirus (SIV),the primate formof HIV. AnApril 2010 studyfoundthatchronic THC treatmentresultedinlower plasmaviral load,lowerlymphnode proviral DNA,andlowerviral gagRNA,irrespective of disease stage (http://www.fasebj.org/cgi/content/meeting_abstract/24/1_MeetingAbstracts/752.6). A June 2011 studyinAIDS Research and Retroviruses confirmedmanyof these results,showingthatchronicTHC administrationdecreasedearlymortalityfromSIV infectioninrhesusmacaques,withanassociated decrease inplasmaandCSF viral loads(http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131805/). The studyalsoanalyzed THC in vitro,findingthe compound decreasedSIV viral replicationinMT4-R5 cells. A December2011 studyin Journalof NeuroimmunePharmacology revealedTHCandanothercannabinoid knownas CP55940 couldreduce the migrationof microglial-like cellstowardsthe proteinTat. Thisis significantbecauseTatisimplicatedinHIV neuropathogenesis; thus, inhibitingTatcan potentiallyhelp control HIV (http://www.ncbi.nlm.nih.gov/pubmed/21735070). Anothersignificantstudy carriedoutby the Mount Sinai School of Medicine andpublishedMarch2012 demonstratedthatactivatingCB2 receptors,butnotCB1 receptors,“reducedinfectionof primaryCD4+T cellsfollowingcell-free andcell- to-cell transmissionof CXCR4-tropicvirus” (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0033961). The report concludedthatCB2 agonistsmay be beneficial fortheirantiviral effectsagainstCXCR4-tropicvirusesin late HIV-1infectionstages. The role of cannabinoidsfortreatmentof epilepticconditionshasbeengainingpopularity recently,andseveral veryprominenttreatmentcasesare discussedinthe case sections. A 1981 study in the Journalof Clinical Pharmacology suggestedthatcannabidiolcouldbe therapeuticallyeffective againstthree of the four majortypesof epilepsy,includinggrandmal,cortical focal,andcomplex partial seizures(http://www.ncbi.nlm.nih.gov/pubmed/6975285). A September2003 studyin JPET useda rat pilocarpine model of epilepsytotestthe effectivenessof THCand anothercannabimimeticonseizures – treatment“completelyabolishedspontaneousepilepticseizures” (http://jpet.aspetjournals.org/content/307/1/129.full). The studyalsotestedaCB1 antagonist,and foundusingitto blockCB1 receptorssignificantlyincreasedseizure duration. Anotherobservationwas that an endogenouscannabinoidknownas 2-arachidonylglycerol significantlyincreasedduringseizures, suggestingthatendocannabinoidsalongwithphytocannabinoidsmodulate seizure activitythroughCB1 activation. A verycomprehensive June2012 studyin Seizure describedthe effectsof cannabidiol onthree modelsof seizures(http://www.ncbi.nlm.nih.gov/pubmed/22520455). A previousstudybythe same teamshowedthatcannabidiol reducedseizureseverityandlethalityin the in vivo model of pentylenetetrazole-inducedgeneralisedseizures. Inthisstudy,the acute pilocarbine model of temporal lobe seizure andthe penicillinmodel of partial seizure were examinedthroughCBDadministrationto rodentsat levelsof 1,10, and100mg/kg. In the pilocarbine model,all levelsof CBDdosessignificantly reducedthe numberof animalsexperiencingthe mostsevere seizures. Inthe penicillinmodel,CBD
  • 9. 9 dosesof 10mg/kg and 100mg/kg significantlyreducedpercentage mortalityasaresultof seizures,but all levelsof dosesdecreasedthe numberof animalsexperiencingthe mostsevere tonic-clonicseizures. Inflammationisatthe core of manydiseases,andmanystudiesimplicate cannabinoidsin controllingexcessive inflammation. Dr.Raphael Mechoulam, amongothers,holdsapatentonthe use of cannabidiol totreatinflammatorydiseases. The diseaseslistedinthe patentincluderheumatoid arthritis,multiple sclerosis,ulcerative colitis,andCrohn’sdisease (http://www.patentstorm.us/patents/6410588/fulltext.html). A detailedstudyinthe Journalof Clinical Investigation alsodescribedthe abilityof the ECSto mediate protectivesignalsthatreduce inflammation(http://www.ncbi.nlm.nih.gov/pmc/articles/PMC385396/). Anotherstudypointedtothe abilityof cannabinoidstomodulateinflammatoryanddegenerativeneuronal damage inmultiple sclerosis,alsoindicatingthatthe ECSis dysregulatedinthe disease (http://brain.oxfordjournals.org/content/130/10/2543.full). The resultspointtothe needforexternally regulatingthe ECSto achieve effective MStreatment. Furthermore,aJuly2003 study foundthat cannabinoidsinhibitedneurodegenerationandprovidedneuroprotectionfrominflammatorydiseases (http://brain.oxfordjournals.org/content/126/10/2191.full). Furthermore,apatentexistsonTHCfor treatingandpreventingsymptomsof MS (http://www.patentstorm.us/applications/20060167084/fulltext.html). A summarizingstudyinthe Journalof the NeurologicalSciences hypothesizedthatthe ECScan provide neuroprotectioninCNS inflammatorydiseases(http://www.ncbi.nlm.nih.gov/pubmed/15894331). Chronicpainis a symptomof manydiseasesanda conditioninitself. Painisthe ultimate driver of desperationandthe sensationthatdestroysall happinessinlife. Itleadspeople todepressionand suicide. Currentmethodsfordealingwith painrelyalmostentirelyonopiates,addictive narcoticsthat cannot provide long-termreliefandresultinahost of terrible side effects,suchasconstipation,mental disconnection,andwithdrawal. The scientificandexperiential evidence suggest thatcannabinoidsare the besttreatmentforpain. A February2003 studystatedCB2 activationinhibitsacute,inflammatory,andneuropathicpain responses(http://www.ncbi.nlm.nih.gov/pubmed/12550743). Later that year,a studyin Anesthesiology referredtocannabinoidreceptoragonists’abilitiestoinhibitinflammatoryhyperalgesia,anincreased sensitivitytopain (http://journals.lww.com/anesthesiology/Fulltext/2003/10000/Inhibition_of_Inflammatory_Hyperalgesi a_by%20.31.aspx). A July2006 studyin CurrentNeuropharmacology demonstratedthatactivationof cannabinoidreceptorsmodulatedpainthresholds,reducedinflammation,andevenworked synergisticallywiththe endogenousopioidsystem (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430692/). An earlier1999 studylinkedanandamide withpainmodulation(http://www.pnas.org/content/96/21/12198.full). In2010, a Public Library of Science article postulatedcannabinoiduse asatreatmentformanagingpostoperativepain,andstated that endocannabinoidsinhibitednociceptive painprocessingthroughactivationof bothCB1 andCB2 (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878341/). A 2006 studyin CurrentMedicalResearch and Opinion testedTHCtreatmentonfibromyalgiapatientswheresignificantreductionof painwas observed,althoughseveralpatientswithdrew fromthe studydue toadverse side effects,mostlikely psychoactive innature (http://www.ncbi.nlm.nih.gov/pubmed/16834825). A May 2012 studyin The Journalof Neurosciencedemonstrated thatthe CB1 receptorwasassociatedwithbothreducedpainand
  • 10. 10 neurotoxicityproducedbychemotherapy,specificallythe chemotherapeuticagentcisplatin (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366638/). A fantasticsummaryof cannabinoidpain-reductioneffectsisdetailedinthe June 2003 issue of Journalof Pain and SymptomManagement,viaalettertothe editor (http://www.jpsmjournal.com/article/S0885-3924(03)00142-8/fulltext). The overview statesthat, “Cannabinoidsblockpainresponsesinvirtuallyeverylaboratorypainmodel tested.Inmodelsof acute or physiological pain,cannabinoidsare highlyeffective againstthermal,mechanical,andchemical pain, and are comparable toopioidsinpotencyandefficacy.Inmodelsof chronicpain,cannabinoidsexhibit efficacyinthe modulationof bothinflammatory andneuropathicpain.” The article alsodescribesthree caseswhere mere smokedcannabiswasable toreduce heavyopiate use byconsiderable amounts. Giventhatsmokedcannabis delivers cannabinoids inahighlyinefficientmanner,itisastoundingthat smokingstill worksmore effectivelythanpharmaceutical-grade opiates. The most powerful pieceof scientificevidence demonstratinganticancereffectsof cannabis extractsinhumans is a November2013 article in Case Reportsin Oncology (http://www.karger.com/Article/FullText/356446). The article describedthe case of a 14-year old female withterminal acute lymphoblasticleukemiawithaPhiladelphiachromosome mutation. This formof leukemiaismuchmore aggressive thanothertypes. 34 monthsof chemotherapyandradiation failedtostopthe cancer, and the patientwasplacedinpalliative home care. The familydecidedtouse cannabisoil as a lastresort afterconductingresearchindicating potential effectiveness. The firstdose of extractwasgivenonFebruary21st , 2009. Priorto this,from February4th to the 20th , the patient’sleukemicblastcell countrose from51,490 to 194,000. Even afterbeginningthe oil,the count continuedtorise,peakingat374,000 onFebruary25th . However,there wassubsequentlyasharp decrease inblastcount,whichcorrelatedwithanincrease indose. ByDay 39, the blastcount had decreasedto300. The total treatmentlasted78 days,at whichpointthe leukemicblastcellswere almostcompletelygone. Unfortunately,the patientpassedawaydue toa bowel perforation,which apparentlywas causedbythe side effectsof the priorintense chemotherapyregiment. The study concluded, “The resultsshownhere cannotbe attributedtothe phenomenonof ‘spontaneousremission' because a dose response curve wasachieved.Three factors,namelyfrequencyof dosing,amountgiven (therapeuticdosing) andthe potencyof the cannabisstrains,were critical indeterminingresponse and disease control.Byviewingfigure 6,itcan be seenthatintroducingstrainsthatwere lesspotent,dosing at intervals>8 h and suboptimal therapeuticdosingconsistentlyshowedincreasesinthe leukemicblast cell count.It couldnot be determinedwhichcannabinoidprofilesconstituteda‘potent'cannabisstrain because the resinwasnotanalyzed.Researchisneededtodeterminethe profile andratiosof cannabinoidswithinthe strainsthatexhibitantileukemicproperties. These resultscannotbe explainedbyanyother therapies,asthe childwasunderpalliativecare and wassolelyoncannabinoidtreatmentwhenthe response wasdocumentedbythe SickKidsHospital. The toxicologyreportsruledoutchemotherapeuticagents,andonlyshowedhertobe positive forTHC (tetrahydrocannabinol) whenshe had‘arecentmassive decrease of WBCfrom350,000 to 0.3' inducing tumor lysissyndrome,asreportedbythe primaryhematologist/oncologistatthe SickKidsHospital. Thistherapyhas to be viewedaspolytherapy,asmanycannabinoidswithinthe resinousextract have demonstratedtargeted,antiproliferative,proapoptoticandantiangiogenicproperties.Thisalso needstobe exploredfurther,asthere ispotential thatcannabinoidsmightshow selectivitywhen attackingcancer cells,therebyreducingthe widespreadcytotoxiceffectsof conventional chemotherapeuticagents.Itmustbe notedthatwhere ourmost advancedchemotherapeuticagents
  • 11. 11 had failedtocontrol the blastcountsand had devastatingside effectsthatultimatelyresulted inthe deathof the patient,the cannabinoidtherapyhadnotoxicside effectsandonlypsychosomatic properties,withanincrease inthe patient'svitality.” (Note:HempOil referstoTHC-richcannabis-derivedextract,nothempseedoil) Reportsof successwithcannabisstretchback to the post-Civil Warera. The March 1868- February1869 issue of TheMedical Record recordsseveral casesof physiciansusingcannabisextractsin theirpractice (http://books.google.ca/books?id=8DVYAAAAMAAJ&printsec=frontcover). Twocasesare attachedbelow.
  • 12. 12 Thisconcludesthe study-level analysis,buthundredsof furtherstudiesandnewsarticlescanbe foundat http://www.letfreedomgrow.com/cmu/Grannys%20List%20January%202013.pdf. The listof studies,collectedbyanactivistknownasGranny StormCrow,features research showingthe effectivenessof cannabinoidsfornearlyanydisease imaginable. Inadditiontothe diseasesdiscussed above,the listcontainsstudiesrelatingtoADD/ADHD,addiction,depression,Parkinson’s,and osteoporosis. Effectsonless well knowndiseasesare alsodocumented,likeMeige’ssyndrome and Niemann-Pickdisease. Cannabisisfurther useful forconditionswe donotthinkof as serious,suchas the hiccups. Much is lefttobe learnedaboutthe endocannabinoidsystemandits complex interactions with phytocannabinoids. The exactmechanismsof ECSfunction,anddysfunction, are still notentirely understood. Despitethe vastmysteriouslandscape ahead,manyconcrete observationscanbe gleaned fromthe existingresearch,whichthankfullyisstillquite robust. First,bothendocannabinoidsand phytocannabinoids exerttherapeuticeffectsforvirtuallyanydisease. Evensyntheticcannabinoidshave beenshowntoinduce benefitthroughactivationof cannabinoidreceptors. The ECShas been implicatedinmaintaininghomeostasisthrougha manybodysystems; thishomeostaticregulatory propertywouldexplain whycannabinoidsare effective againstsomanydifferentconditions. When examinedapartfromexperientialdata,thisresearchissimplypromising,andnomore. However,given that humansare actuallyusingconcentratedcannabinoidstoachieve cure-levelresultsforconditions where curative powers are potentiallyimplied,thisresearchmustbe takenfarmore seriously. Infact, evenif thisresearchdidn’texist,the magnitudeof the experiential dataisimpossible toignore. Current scientificstudiesgrantlegitimatecredibilityandilluminate cellularmechanismsbywhichthese curative resultsare occurring. In the future,more researchwill reveal notonly more abouthow the ECS functions,butthe beststrains,dosages,andconstituentsforcannabisextractmedicine. Forexample, differentratiosof THC/CBDmay be betterfor differentconditions;likewise,the ideal use of sativa, indica,or hybridstrainsmustalsobe examined,alongwiththe potential rolesof juicingandothernew administrationmethods. Researchersanddoctorsaroundthe countryare movingquicklytoembrace the inevitable future of cannabismedicine. Inlate September2013, GW Pharmaceuticalsannouncedthe startof clinical trialsof a newcannabistreatmentforepilepsy (http://www.leafscience.com/2013/09/20/around-world-researchers-begin-clinical-trials-cannabis- epilepsy/). InNovember2013, theyannouncedthe commencementof trialsforrecurrentglioblastoma multiforme, atype of braincancer (http://www.prnewswire.com/news-releases/gw-pharmaceuticals- commences-phase-1b2a-clinical-trial-for-the-treatment-of-glioblastoma-multiforme-gbm-
  • 13. 13 231391971.html). Dr. Orrin Devinsky,Directorof the Comprehensive EpilepsyCenteratNew York University,alsorecentlyreceivedFDA approval fora clinical trial of CBDfor childrenwithepilepsy. A recentstudyinSpain,fundedbythe SpanishMinistryof Science andInnovationandComplutense University,resultedinthe developmentof amicroparticle deliverysystemforTHC (http://www.leafscience.com/2013/09/07/cancer-researchers-develop-micro-delivery-system-for-thc/). Usingsuch a deliverysystemwasshowntobe betteratinhibitingcancercell growththanTHC alone,as the microparticlesallow forbetterabsorptionandsustainedrelease. Dr.SeanMcAllister,ascientist mentionedabove whohasconductedresearchonCBDand breastcancer,is seekingtoinitiateFDA- approvedtrialsforCBD and cancer inhumans(http://www.leafscience.com/2013/11/08/cancer- researchers-verge-human-trials-cannabis/). A December11th , 2013 pressrelease fromGWPharmaceuticalsannouncedaUSPatent Allowance forthe use of cannabinoidsintreatingglioma (http://www.gwpharm.com/GW%20Pharmaceuticals%20plc%20Announces%20US%20Patent%20Allowa nce%20for%20Use%20of%20Cannabinoids%20in%20Treating%20Glioma.aspx). Itisimportantto point out thispatentrelatestothe treatmentof cancer,not side effectsof chemotherapy. “The subjectpatentspecificallycoversamethodfortreatinggliomainahumanusinga combinationof cannabidiol (CBD) andtetrahydrocannabinol (THC) whereinthe cannabinoidsare ina ratioof from1:1 to1:20 (THC:CBD) withthe intenttoreduce cell viability,inhibitcell growthorreduce tumor volume.” An earlierpatentfiledonMarch 11, 2011, coversthe general applicationof phytocannabinoids inthe treatmentof cancer(http://www.google.com/patents/US20130059018). As more researchisconductedintocannabinoidmedicine,furtherinnovationsandusesare boundto be discovered. Fornow,the scientificevidence stronglysupports every anecdotal claim. Thispaper’scoverpicture comesfromthe followingscientific article - http://www.cell.com/trends/pharmacological-sciences/abstract/S0165-6147(09)00128-X.
  • 14. 14 2. History of Rick Simpson and Phoenix Tears Giventhe multitude of referencestoRickSimpsonthroughoutthisreport,andhiscritical importance tothe beginningof the moderncannabisextractmovement,hishistoryisdescribedindetail below. RickSimpsonwasborninSpringhill,NovaScotiaonNovember30,1949. He beganworkat the age of 16, and transitionedtoacareerin powerengineeringat18. Rickworkedas an engineeruntil 1997, whenhe sufferedawork-relatedinjuryandwasdiagnosedwithpost-concussionsyndrome. He was prescribedanumberof drugsto alleviate hiscondition,butnone were effective. In late 1998, Rick watchedan episode of “The Nature of Things”,inwhichDr.David Suzuki interviewedmedical marijuanapatientswhohadachievedastoundingresultswithcannabis. This promptedRickto try itfor himself. He quicklynoticedthatsmoking cannabisdidmore forhiscondition than anyof the pillshe wastaking. Despite the effectivenessof hisself-administeredmedication,Rick’s doctor wouldnotprovide alegal prescriptionforcannabis,statingthe herbwas“badfor the lungs”. In response,Rickaskedif itwouldbe bettertoextractthe essential oilsfromcannabis,knowingsucha
  • 15. 15 methodwouldbypassthe needforsmoking. Hispleafailed,asthe doctorstill refusedtowrite a prescription. Nonetheless,Rickdecidedtopursue thiscourse anyway,andthroughtrial-and-error developedanacceptable methodforproducingcannabisoil. Until 2001, Rickcontinuedtakingprescriptionmedicinesuntilhisdoctortoldhimthere was nothingmore theycoulddo. Rick thenceaseduse of pharmaceuticals,leavingcannabisoil ashisonly medication. Thiscourse greatlyimprovedhiscondition. In late 2002, Rick wasdiagnosedwithskincancer,whichwaspresentonthree partsof his body; twopatcheson hisface andone on hischest. InJanuary 2003, Rick had one areaof skincancer removedsurgically,withthe remainingtwopartsscheduledtobe removedlater. Shortlyafterthe surgery,Rickrecalledaradioshowhe’dheardabout the 1974 Universityof Virginiastudyindicating tetrahydrocannabinol inhibitedcancergrowth (http://www.ncbi.nlm.nih.gov/pubmed?cmd=Retrieve&list_uids=1159836). Rick knew cannabisoil containedconcentratedTHC,sohe decidedtophysicallytestitonhimself. He appliedhomemadeoil to bandagesandplacedthemdirectlyonthe skincancersites. In fourdays,the cancers were gone. Excited,Rickwentbackto hisdoctor’soffice toinformthemthat he had curedhimself withcannabisoil, but the reactionsfromboththe receptionistanddoctorwere negative. Afterhisincrediblepersonalexperiences,Rickdecidedhe wantedtohelpothers. He began growingcannabisinmassive quantitiesinhisbackyard,usingittoproduce thousandsof gramsof oil, whichhe gave away forfree to anyone inneed. He quicklyobservedthatcannabisoil exertedpanacea- like effects. Iteliminatedanytype of cancerhe came across andreversednearlyanytype of medical condition. Diabetes,chronicpain,multiple sclerosis,nerve damage,inflammatoryandautoimmune disorders,andmental conditionsbecame completelycontrolledordisappeared. Mostpatientscame to Rick as a lastresort,not believingsomethingassimple ascannabisoil couldreallywork. The standard treatmentprovidedwas60 gramsto be usedover90 days;thiswas the dosinglevel Rickobservedwas necessarytoachieve curative effects. However,as massingevidenceindicates,sometimesmuchlessor much more cannabis oil isneededtorealize sucheffects. Rick’sactivitiesattractedbothmediaandlaw enforcementattention. Inlate 2006, storiesabout Rick appearedonGlobal National NewsandGlobal MaritimesEveningNews,twopopularCanadian newsprograms. Priorto that, onAugust3rd , 2005, the Royal CanadianMountedPolice (RCMP) raided Rick’shome,andconfiscated1,190 cannabisplants (http://www.cumberlandnewsnow.com/Justice/2007-09-13/article-370849/Seized-marijuana-plants- had-value-up-to-830000-RCMP/1). Althoughthe citedarticle states1,190,Rick saidthe plantcount was actually1,620; one of the newsreportsalsomentionsacountnumberaround1,600. The raid ledto a trial in September2007, where Rickfacedchargesincludingpossessionof lessthan30 gramsof cannabis,possessionof lessthanthree kilogramsof tetrahydrocannabinolforthe purpose of trafficking, and unlawful productionof cannabis. He wasfoundguiltyonall charges. Whendiscussingan adjournmentforsentencing,Ricksaidthe followingtoJudge FelixCacchione: “It may be betterto lockme up rightnow.As soonas I get home I’mgoingto treatmy patients.I’m goingto growthat plantuntil the day I die,soI mightas well be putinjail today.I can’t stopinthe middle of [treatment].People’slivesare atstake here.” (http://www.cumberlandnewsnow.com/Justice/2007-09-19/article-381209/Simpson-guilty/1).
  • 16. 16 Simpsonwasscheduledtoreturntocourt forsentencingonNovember30, 2007. However,while awaitingsentencing,SimpsonwasarrestedagainfortraffickingTHC,and wasremandedforfourdays until beingreleased. WhenSimpsonwassentencedforhisfirstcharges,he receiveda$2,000 fine, prohibitiononownershipof firearms(asisthe case withmostdrug charges),andone day custody, deemedservedbyhiscourtappearance. Judge Cacchione explainedhisdecision,saying,“Mr.Simpson has a sincere belief he hasa cure withthisoil and shouldbe commended,butinreality,he broke the law”(http://www.cumberlandnewsnow.com/Justice/2008-02-11/article-382416/Simpson-considers- leaving-country/1). Inearly2008, Rickreturnedto court to face the charge relatedtohis secondarrest, and wassentencedtoeightdaysincustodyby Judge Carole Beaton. Aswiththe firstcase,the custody time wasdeemedservedbyRick’spreviousremandtime. “Mr. Simpsonisinan unusual position,because unlike otherpeople engagedinthe drugtrade, he was not engagedintraffickingforfinancial gain,"saidJudge CaroleBeaton."He wasengagedinan altruisticactivityandwasfirminhisbelief thathe washelpingothers”(http://www.salem- news.com/articles/december052009/rick_simpson_bk.php). Withtwo separate legal incidentshappeningonlymonthsapart,Rickwasforcedto cease his activitiesforsome time. InNovember2009, Rick wenttoAmsterdamto receive the HighTimes FreedomFighterof the YearAward(http://www.hightimes.com/read/rick-simpson-seeks-political- refuge-europe). While inEurope,Rick’shome was raidedagainbypolice,resultinginmore cannabis productionandpossessioncharges,alongwithchargesrelatedtothe breakingof hisfirearms prohibition. (http://www.cumberlandnewsnow.com/Justice/2009-12-17/article-818327/Summons- issued-for-cannabis-crusader/1). Asa result,RickdecidedtostayinEurope for several years,wherehe continuedtoeducate people personallyandthroughhisorganization,Phoenix Tears. The 2009 charges were withdrawnin2012 by CrownattorneyDougShatfordaftera forfeiture applicationof seizeditems was approved(http://www.cumberlandnewsnow.com/News/Local/2012-05-14/article- 2978460/Charges-against-Simpson-withdrawn/1). Currently,RickandPhoenix Tearsare lookingtotake advantage of the legalizationlaw inColoradotoagain provide cannabisextractmedicine toanyone who needsit. Rick Simpson’sendeavortoheal people withcannabisoilwaspublicizedinthe documentary Run From theCure, releasedFebruary2008 (http://www.youtube.com/watch?v=pjhT9282-Tw). The documentaryelaboratesuponRick’sstoryandhow he discoveredcannabisoil couldeliminate various cancers andotherdiseases. The filmalsoprovidesstep-by-stepinstructionsonhow tomake cannabis oil and featuresinterviewswithcuredpatients,includingthose once deemedterminal. Itisof note that much betterprocessesforextractingcannabisoil have beendiscoveredsince the publishingof Run From the Cure. Alcohol,vegetable oil,carbondioxide,and othernon-petroleum-basedsolventsare fast becomingthe choice waystoprocesscannabisintoextracts. Furtherdiscussedinthe documentaryisanincidentinvolvingRickDwyer,formerpresidentof the Maccan Branch of the Royal CanadianLegion. AfterseeingsuccesswithhisfatherEdforterminal lungcancer, Dwyertriedtoshare the informationthroughhisLegionbranch. However,uponlearningof whatthe branchwas promoting,ProvincialCommandintervenedandremovedDwyerfromhisposition, claimingthatadvocatingthe use of an illegal substance wasunacceptable (http://www.canada.com/globaltv/national/story.html?id=70817eb6-a515-4af7-bf0d-3050413f0ebc).
  • 17. 17 Thistrendof disregardanddisbelief forcannabisextractmedicinehasbeenaperpetuallystrong presence. RickDwyer’sincidentwasonlythe beginning –RickSimpsonalsoexperiencedrejectionfrom everyorganizationhe contacted,includingcancerresearchcenters. He offeredtopresentevidence directlyfrompatientsprovingthe effectivenessof cannabisoil,butnoone listened. Itwasnot even until August2013 that the firsttrulymainstreamtestimonial forcannabisextractmedicinewasshown to the world,inthe form of Dr. SanjayGupta’s Weed documentaryanditsdiscussionof child-patient Charlotte Figi. Throughthe use of non-psychoactivehigh-cannabidiol oil (whichdiffersfromtraditional psychoactive high-THCoil),Charlotte’sseizuresdroppedfrom300 grand mal seizures aweektoless than three minorseizuresamonth. The use of cannabisoil wascommencedonlyaftereverypossible combinationof powerfulpharmaceuticalsfailed. Threehundred severeseizures a weekto less than three minorseizures a month. Charlotte’scase isjustthe latestinanincrediblylonganddiverselistof successesthathave beenachievedsincethe releaseof Run FromtheCure. Interestinglyenough,RickSimpsoniscitedinthe November2013 CaseReportsin Oncology study inthe previoussection,ashe helpedassistthe studiedpatientwithproducingherownoil. Run From theCure was directedbyChristianLaurette,whohimself hadaverypositive healing experience withcannabisoilforbackproblems. He iscurrentlydirecting Run FromtheCure2, whichwill feature manyof the developmentsthathave occurredsince the firstfilm.
  • 18. 18 3. Individual Case Reports Patientshave alwaysbeenthe central focusof the cannabisextract movement;real people whohave facedreal prospectsof painand death,yetrecoveredsuccessfully throughthe use of cannabisextract medicine. The followingtestimonialsare pulledprimarilyfromsocial mediaandnewssources,aswell as frompersonal interviewsof the author. Several casesalsoinclude officialmedicaldocumentationof diagnosisandsubsequentremission. The most fittingplace tostart isthe documentary Run Fromthe Cure,whichfeaturedseveral patientswhoexperiencedincrediblehealingbenefits. Eric Donkinhad fouropen-heartsurgeriesandfive pacemakers,andthroughthe use of Rick’s oil,wasable to live life nearlypainfree andgobackto work. Doctorshad toldhimhe wouldonlybe able to siton the couch and watchTV for the restof hislife. Ericalsoremarkedthatthe oil waseffective for hisfather’scancer,andit was because of hisfatherthathe beganonthe oil aswell. Rick Dwyersufferedfrommajordepressionsince 27,alongwithpanicattacks. Three back injuriesresultedinchronicbackpainwithconstantaching. The oil cut downhispanic attacks,reduced back aches,and continuouslyimproveddepressionandanxietysymptoms. Debbie Donkinhadsuspectedskincanceronher shoulder,andafterusingthe oil fortwoweeks (byputtingthe oil ona bandage,andreapplyingoil/changingthe bandage afew timesthroughout),the site wascompletelyclear. Cecil Hoeghad melanomaonhisface,whichhadpreviouslybeentreatedmanytimeswith radiation. Althoughthe radiationtreatmentswere ineffective, Rick’scannabisoil provedeffective at finallygettingridof the cancer. Margaret Dwyerusedcannabisoil withefficacyformigraines,anovariancyst,arthritis,skin allergies,stomachproblems,and evensnoring. The most dramaticcase featuredisJamesLaBlanc,a patientwithterminal cancerwhowas healedwithcannabisoil. WhileJames’storyisrelativelybrief inthe documentary,the authorof this reportspoke extensivelywithJamesin2008, and recorded several importantdetails. Some information isalso takenfromthe original incarnationof the Phoenix Tearswebsite.
  • 19. 19 Jameswasdiagnosedwithstomachcanceron May 18th , 2005. Overthe subsequentfew months, LeBlancenduredsurgery,chemotherapy,andradiationtreatments. OnNovember30th , 2005, the cancer wasvirtuallygone. ItreturnedinOctober2006, and thistime hadspreadthroughoutJames’ lymphnode system. InNovember2006, LeBlancwas giventwomonthsto live,asthe cancer was completelyuntreatable. Onlypalliativemedicinewasprescribed. ItwasinDecember2006 that LeBlanc became aware of cannabisoil,andwas broughtto AmhersttomeetRickSimpson. He was initially skeptical of the endeavor–like mostpeople atthe time,he wasusingcannabisoil asa last resortwith little hope. AfterspeakingextensivelywithRick,LeBlanc’shopeswere raisedandhe startedthe oil on January1st , 2007. OnApril 4th , 2007, LeBlanchad hisfirstCT scan since startingthe oil andreceivedthe resultsonApril 24th . The doctor presentedJameswithextremelygoodnews;notonlywasthe cancer not spreading,butitwasdying. By late July,the secondCTscan showedthatonlya small bitof cancer remained,andbythe final CTscan in December2007, the cancer wascompletelygone. Afterbeating terminal cancer,Jamesreturnedtowork. Rick Dwyer,apatientmentionedabove andformerpresidentof the Maccan Branch of the Royal CanadianLegion,spoke onGlobal MaritimesEveningNewsinDecember2006. He spoke aboutissues withthe RCMP and the successhisfather, 82-year-oldEdDwyer, experienced throughcannabisoil consumption. The treatmenthelpeddrainfluidfromEd’slungs,repairhisprostate,andeliminate his needforinsulintocontrol hisdiabetes. Throughthe use of cannabisoil,the fluidfromEd’slungswas drained,hisprostate wasrepaired,andhe nolongerneededtotake insulinforcontrollinghisdiabetes. Most importantly, Ed’sterminal lungcancerwasheldatbay,despite atone pointhavinga prognosisof only24 hoursto live. Later inthe documentary,RickDwyer discussedhow he came tomeetRick Simpson andlearn the truth of his claims bytalkingwithcuredpatients. AsDwyer stated,“IinvestigateditasI should’ve.” Despite effortstoshare the informationwithProvincial Commandandsolicitanhonestreview of the claims,theydidnotlisten. Dwyerevenstartedapetitionaskingparliamenttoenactlegislationin supportof clinical testingoncannabisoil.
  • 20. 20 Insteadof examiningthe evidence,LegionCommandcame inandshutdownthe Maccan Branch. Rick Dwyer’seffortstoshare the scientificandhumanevidence were ignored. Provincial Commandonly cared that the Royal CanadianLegionname andinsigniawere notusedtopromote illegal information. Steve Wessel,CommandChairmanof NovaScotia,said sharingsuchinformationcoulddamage the integrityandreputationof the Legion. Giventhatno actual medical documentationof curative resultswere includedin Run Fromthe Cure,the documentary wasinitially,andstill tothisday,metwithheavyskepticism. Tocounterthis skepticism, Rick Simpsonsimplystated,“If youdon’tbelieveme,putsome oil onaskincancer, and watch itdisappear.” Indeed,since the 2008 release of Run FromtheCure,thousandsof people have takenthischallenge andmore, seeingRick’sseeminglyabsurdclaimsconfirmedtime andtime again. DavidTripletttreatedskincanceronhisnose withcannabisoil,anddocumentedthe curative resultsinhismini-filmCured:A CannabisStory,releasedinJuly2010. (http://www.youtube.com/watch?v=JPm0Jq9bj98).
  • 21. 21
  • 22. 22 The above imagesare capturedfrom the documentary,whichalsoincludesfurtherimagesand information. A womannamedMaggie Perondiscussedthe use of cannabisoil forher65-year oldfather,who had squamouscell carcinomaonhishands(http://www.youtube.com/watch?v=Ui68B_rjzLk). He hadto deal withconstantscabs,pus,sores,and pain. Maggie boughtcannabisoil fromGersh Avery,whooften goesby the pseudonymPeanutButter. She convincedherdadtotry it topicallyone night,andthe very nextdayhe reportedsubstantiallyreducedpain. Overamonth,the scabs and soresalmostcompletely disappeared. Hardlyanyscaring,and pushad gone away completely. Maggie:“That’sthe mainthing, there’snopain.” GershAveryhas treatedmanypeople andinformallycollectedreportedresultsinaspreadsheet. He insistedthiswasnota formal studyinthe slightest,andwasjustobservationshe collectedfrom patients. Ratingsare on a 1 to 10 scale,with1 beingthe leastsevere and10 beingthe mostsevere symptomintensity. Measuredsymptomsincludeacid,tension,gurgling,diarrhea,andpain.
  • 23. 23 A newsreportfeaturinganchorsEricSingerandHeatherSkoldof ABC NewsChannel 13discussedthe use of cannabisoil forneckcancer (http://www.youtube.com/watch?v=0F3mTf1z3Yo). BrettStrauss firsthad cancer in2007, andafter beatingittraditionally,the cancerreturnedinthe formof five malignanttumorsinJanuary2010. He decidedtotrytopicallyusingacannabisextractbalmon hisneck, and inMarch 2010, doctorsconfirmedonly one tumorwasmalignant. Afterthisexperience,Brett wantedtoresearchthe effectsof cannabisoil forothercancerpatients. Althoughthere isnofurther readilyavailable material regardingBrett’sendeavororfurthercancertreatment,hisstoryis notable nonetheless. ShonaBanda isa particularlyunique patientandactivistwhohas Crohn’sdisease. Shonabattledfor eightyearsagainsta verysevere case of Crohn’s,usinganarray of powerful pharmaceuticalsincluding Remicade,which oftenhasseriousandpainful side effects. Whenshe beganusingcannabisoil inMarch
  • 24. 24 2009, herconditiongreatlyimproved. The drastic,overwhelmingsuccesspromptedShonatowrite a bookabout herexperience called LiveFree or Die. The bookstartedas a journal thatShonakeptto documentthe effectsof cannabisoil,andshe expandeduponthe journal withotherinformation to create her book. Live Free or Die isespeciallypowerful becauseof Shona’scourage toreveal the specific waysin whichCrohn’saffectedherlife. Onseveral occasionsshe thoughtshe wasgoingtodie. The other interestingaspectof Shona’sstoryisthe wayshe producedcannabisoil. Havingseen Run From theCure and knowingshe couldn’tacquire the recommendedamountsof cannabistomake oil from(inthe documentary,apoundor as little asone ounce isrecommended),Shonabelievedshe wouldnevertryit. However,aftervaporizingcannabisinaglobe-type device,she noticedresidue accruing alongthe sides,whichlookedlikethe cannabisoil she’dseenin Run FromtheCure. With nothingtolose,Shonabegancollectingandconsumingthe oil residue incapsules. Withinaweekanda half,she noticedremarkable improvements; althoughsome abdominal paininitiallyintensified, Shona attributedthistoscar tissue changingandfallingoff. Overthe nextfew months,asidefromperiods where cannabiswasunavailable,Shonacontinuouslyimproved. She wentfromliterallybeingonthe verge of deathto feelingalmostcompletelydisease-free. The detailsinherbookare trulyremarkable, and a must-readforanyone legitimatelyinterestedinthisissue. The painShonaovercame withher improvisedformof cannabisoil isnothingshortof incredible. Furthermore,otherpatientswithout access to large amountsof cannabishave usedhervaporizationmethodtomake oil fromsmall quantities. Shonarecordedabrief summaryof herstory in2010 (http://www.youtube.com/watch?v=4cQrT0sDxyc). Herbook Live Free orDie is available inhardcopy and the Kindle (http://www.amazon.com/Live-Free-Die-Reclaim-Life/dp/1449045561 and http://www.amazon.com/Live-Free-or-Die-ebook/dp/B005GHM244). A videopostedonOctober5,2011 discussedthe storyof anelderlywomanwhoovercame Stage IV cancer and lupuswithcannabisoil (http://www.youtube.com/watch?v=jxis8lqaEGE). InJanuary2011, the woman(knownas“Granny”) was toldshe had“days, weeksatthe most” tolive,asher condition was especially taxing. Inadditiontothe cancer, she was paralyzedfromthe leftside of herface,starting
  • 25. 25 fromthe jaw, to the waist. A compassionate strangerlearnedof herstoryand donated cannabisoil to help. A litanyof improvementsimmediatelystarted afterGrannybeganthe treatment,including reductionof tumors,almostcomplete eliminationof chronicpain,ceasingof constantvomiting,and remarkable concurrentimprovementsforlupusandfibromyalgia. Grannyforewentchemotherapyand surgeryforthis path,and stronglybelieves,basedonthe poorprognosisfromdoctorsandthe state she was in,that if notfor cannabisoil she wouldbe dead. Cannabisoil hasprovento be effectiveagainstevenlong-standingchronicpain (http://www.youtube.com/watch?v=gu5VNQHxKkU). A videoreleasedinOctober2011 featuresTomas Harner,who for30 years enduredbackpainas a resultof accidents. Inthe last 10 years,he saidhis conditionbecame worse,anddoingsimple tasks likeputtingonshoeswere becomingdifficult. Within the firstweekof consumingcannabisoil,the sharppainswhichinhibitedhismovementswere gone. Tomas maintains awarenessof hisinjury,butthe vastmajorityof his painhas disappearedandhisrange of movementhasimproveddramatically. He believesthattakingmore oil will eliminate remnantsof pain.
  • 26. 26 A medicinal cannabisoil producernamedAamannDegarthhas observed amazingresultswithcannabis oil,andhas documentedthe resultsinsharedvideos. One November2011 account detailshiswork withreflex sympatheticdystrophy,now more commonlyknownascomplex regionalpainsyndrome (http://www.youtube.com/watch?v=Xvw19POCN4g). Aamannwasreferredtothe RSDpatientbya friend,andmanagedto procure oil for her. The patienthadextremelylittle experience withcannabis, and Aamanntookmeasurestoensure she startedoff slowly. He packagedthe oil invariousdelivery mechanismsandsentit off. He wasunsure of what the effectswouldbe,asRSDwas a conditionhe hadn’theardof. The day afterstartingthe oil,the patientreportedbeingpainfree,rightfromthe first dose. Aamannwassurprisedbythe speedof thisparticulartreatment. A laterJune 2012 videofrom Aamannprovidedanupdate onRSD/CRPStreatmentswithcannabisoil,reportingthatotherpatients had experiencedimmense success(http://www.youtube.com/watch?v=OvEztT4VHCg). Again,even small amountsof oil were reportedtobe effective atstoppingpain. Aamannhas treatedanddocumentedawide varietyof conditions,includingallergies (http://www.youtube.com/watch?v=V0fgTIorzXI),ADD (http://www.youtube.com/watch?v=C4ljMHUW4uI),neuropathy (http://www.youtube.com/watch?v=p4Y0CW10RTg),insomnia (http://www.youtube.com/watch?v=n1odhWwHSps),cyclical vomitingsyndrome (http://www.youtube.com/watch?v=3tVtUf1hTQs), lymedisease (http://www.youtube.com/watch?v=d_HAOkPSzgw)andmore. A particularlyintensecase describesa patient’sexperience withtrigeminal neuralgia,aconditionsoterrible itisnicknamed“suicidedisease.” TN isa neuropathicdisorderthatinvolvesepisodesof intense,stabbingpaintothe face. Aamann providedcannabis oil toa TN patientand observedthatit worked remarkablywell,withthe patient reportingzeroproblems (http://www.youtube.com/watch?v=S495AUPbka0). Before movingforward,itisimportanttohighlightthe trendregardingcannabisoilandpain. Currently,the primarytreatmentforpainisopiates. Manypatientshave reportedthatnotonlyare opiatesineffectiveoverthe long-term,buttheycause immense physical discomfort,cloudinessof the
  • 27. 27 mind,andorgan damage. So manypatientshave stronglyinsisted thatcannabisoil isfarmore effective than opiateswithnone of the side effects. Theyfeel cannabinoidtreatmentattacksthe rootsof their pain,ratherthan providingamere numbingeffect. Sucheffectsare difficulttoobjectivelymeasure because theyare entirelysubjective,butthisremarkablystrongtrendissomethingthatcannotbe ignored. A January2012 videofeaturingthree patients,Mike Stone, Tom,andJeff,illustratedthe benefitsof cannabisoil formultiplesclerosis,rheumatoidarthritis,andmesothelioma (http://www.youtube.com/watch?v=V-uGtEHzZUE). Mike hadbeendiagnosedwithrelapsing-remitting multiple sclerosis17 yearspriorto the video’sfilming. Tocombat the disease,he wasprescribedalitany of drugs,whichcreatedmanyunpleasantside effects,includingsuicidalthoughts. AfterseeingRun Fromthe Cure,Mike decidedtotry a 90-day cannabisoil treatmentprogram. He concurrentlyceased all use of pharmaceuticals. He foundthe oil to workveryeffectively,whileeliminating the remainingside effectsfrompriorpharmaceutical use. The nextpatientfeatured,Tom,wasdiagnosedfouryearspriortofilmingwithsevere rheumatoid arthritis. Lack of treatmentformanyyearscausedextensive damage inhishands. TommetMike Stone, the above patient,ata May 2011 medicinal cannabisinformational meeting. Mike toldTomaboutthe potential benefitsof cannabisoil,andTomwasable to secure some. He startedwithone small dose a day forthe monthof June, while stilltaking hispreviouspharmaceuticals. Afteramonth,he decidedto go for the full 90-daytreatment. InearlyAugust2011, he stoppedtakingmethotrexate,a chemotherapydrugalsousedforrheumatoidarthritis, whichcausedespeciallysevere side effects. By August25th , he startedtakingcannabisoil three timesaday for90 days. Tom’srheumatologisttoldhim that swellingwasanindicatorof if hisrheumatoidarthritiswasactive – afterthe treatment,Tom’s swellingcompletelydisappeared,indicatingapparentinhibitionof the disease. He currentlytakesone dose of oil a day to helphimsleepatnightandkeepthe effectsof rheumatoidarthritisatbay.
  • 28. 28 The third personinthe film,Jeff,foundouthe hadfive tumorsonhisleftlung, diagnosedas mesothelioma. Like Tom,Jeff foundoutaboutcannabisoil from Mike Stone. Mike showedJeff howto make hisowncannabisoil,andJeff begantreatinghimself byputtingtwodropsonhistongue every morningwithaneyedropper. OnDecember21st ,2011, Jeff wastoldall histumorswere gone andhe was cancerfree. “BestChristmaspresentIeverhad,”remarkedJeff. He alsostoppedtakinghisblood pressure medication, givenhisBPhad normalized. Jeff isalsosuccessfullycontrollinghisdiabetes,with hissugar levelsneverbeingover110. He’s off hisallergymedicinesandcholesterol medicinesaswell. He still hassome problemsbreathingasa resultof emphysema. However,overall,Jefffeelshislife has drasticallyimproved. At an eventknownas“Uncle Pete’sCannabisCamp”inJune 2012, where people are taughtaboutthe healingeffectsof cannabisoil alongwithhow tomake it,the testimonial of Joe Crowe wasrecorded (http://www.youtube.com/watch?v=W0nwqBtxXKc). Joe hada fist-sizedtumorinhisupperchest, diagnosedasHodgkin’slymphoma. He hadpreviouslyreceived chemotherapyandbone marrow transplants,butthe treatments were ineffective. Inthe fall of 2011, Joe wasconnectedwithGrow Goddess,a female caregiverinMichigan. The properformswere filedforGrow Goddesstolegally
  • 29. 29 become Joe’scaregiver. Withinthree months of cannabisoil treatment,Joe felthistumorbeganto shrink. By five months,he wascancerfree. On December4th ,2013, Joe releasedanupdate videostatinghe isstill cancerfree afterayear (https://www.youtube.com/watch?v=-spOVv8EobU). He emphasizedthe importanceof continuingto take a maintenance dose of oil topreventcancerfromreturning,especiallydue tothe large amountof environmental toxinshumansare exposedtodaily. Joe now helps otherpeoplemake anduse cannabis oil therapeutically,andatthe endof the videorecountsanexperiencewithaStage IV cancer patient whowentintoremissionwith self-madeoil. A case veryclose to the author isthat of DennisHill. Dennisisanestablishedteacherof meditative practices,andhas writtenseveral booksonmeditationandyoga. He alsoworkedinthe fieldof cancer researchforten years. In February2010, six biopsiesrevealedhighlyinvasive andaggressive prostate cancer.
  • 30. 30
  • 31. 31 Denniswas stunnedtohearthisdiagnosis afterhavinglivedsucha healthylife,butgiventhatprostate cancer wasprevalentinhis family,he knew the possibilityhadalwaysexisted. Priorexperience in cancer researchmade Denniswanttoavoid the traditional routesof chemotherapy,radiation,or surgery,giventhe likelypainful sideeffects. He beganto researchalternativemethodsof cancer treatment,andlearnedaboutcannabisoil. Ashe researchedfurther,he decidedthiswasthe pathfor him. Dennis’treatmentjournal,startingonJuly8,2010, isrecordedonline (https://dl.dropboxusercontent.com/u/27713298/Web/cure/Treatment.html). However,priortothe firstentry,Dennis hadbeenconsumingcannabis-infusedbutter,ashe hadnot acquiredfull-strengthoil yet. Afterprocuringsuchoil,hisconditionsteadilyimproved,until aprostate biopsywastakenon January25, 2011 to determine if the cancerwasgoingintoremission. OnFebruary8th , 2011, Dennis receivedthe newsthathe wascancer free (https://dl.dropboxusercontent.com/u/27713298/Web/cure/Cured.html). The onlypharmaceutical- type treatmentDennisreceivedthroughthisperiodwasthree injectionsof Lupron,anandrogen antagonistwhichcanpotentiallyslowthe rate of cancer growth. However,italone cannotleadtothe shrinkage of tumors.
  • 32. 32 Dennisalsoappearedona programcalled“Spiral Up withAvaMarie” to tell hisstory (http://www.youtube.com/watch?v=Q7ytJu4Zcrk).
  • 33. 33 Denniscontinues totake amaintenance dose of cannabisoil andhasintegratedcancer-fightingfoods intohisdietto ensure he stayshealthy. DustyFrank, a local musician,wasdiagnosedwithprostatecancerinOctober2013 (http://www.cureyourowncancer.org/dusty-franks-story-beating-prostate-cancer-with-cannabis- oil.html). The traditional optionshe waspresentedwithwerenotpreferable due tonegativeside effects,andDustywantedanalternative. He quicklylearnedaboutcannabis oil,andextractedhisown fromraw cannabis. Althoughhisdoctorsadvisedagainstthe treatmentandDustyhimself haddoubts aboutthe oil’sefficacy,he wentaheadwithathree monthregiment. OnJanuary23rd , 2014, a Tesla3 MRI reportstatedthere were nolongeranysignsof cancer (medical documentationfoundatlink above). Perhapsevenmore remarkable thanthe cancerremission wereall the otherside benefits. Bloodpressure normalizedandrelevantmedicationswere discontinued. Aninflamedbig toe joint normalized. Rectal bleeding,chronicspinal pain,shoulderandneckpain,andchronic insomniawere resolved. Sinusproblems,includingpostnasal drip,resolved. Depressionresolved. Severalof these issueshadplaguedDustyforwell overa decade. Furthermore,atleasteightpharmaceutical medicationshave beenreplacedwithcannabisextractmedicine,andthe onlypill Dustytakesnowisa single multi-vitamin. Dustyalso sharedhisstoryon YouTube (https://www.youtube.com/watch?v=SGPTXq6dZHg). He intimatelydescribedhisexperience,whichrepresentswhatmostpatientswhouse thismedicinego through. Interestinglyenough,if Dustyhadnotbegunseeingotherremarkablebenefitsfromcannabis extractsmere daysintohistherapy,he may have stoppedoutof skepticism.
  • 34. 34 MykaylaComstock,a childpatient,hasattractedsignificantattentionrelatedtoherbattle withcancer. In July 2012, Mykaylawas diagnosedwithT-cell acute lymphoblasticleukemia. Feelingsickthroughout May wasthe chief signthat somethinginMykaylawaswrong. The child’smother,ErinPurchase, immediatelyprocuredalegal recommendationforcannabis. MykaylabeganchemotherapyonJuly17th , 2012. Accordingto a local ABC Newsarticle, “Atfirst,Mykaylawasn'trespondingwell tohertreatment, and doctorssaidshe mightneeda bone marrow transplant.Thenshe startedtakingthe cannabisoil pills, hermothersaid.ByearlyAugust,Mykaylawasinremissionandthe transplantwasnolonger necessary”(http://abcnews.go.com/Health/medical-marijuana-year-sparks- controversy/story?id=17814636). Erin alsonotedthat withcannabisoil,Mykaylawasable to avoid usingtraditional painornauseapills,andhasnotlosta single poundsince diagnosis. ByAugust6th , less than a monthafterstartingtraditional therapy,Mykaylawasinremission. She isrequiredbythe medical systemtoundergotwo-and-a-half tothree more yearsof chemotherapytobe certainthe cancer isgone. Nonetheless,the rapiddisappearanceof cancerfromMykayla’sbloodandthe lack of side effectsfromchemotherapyare astoundingfacts. Evenforan adult,chemotherapy usually producesintense sideeffects –fora child,sucheffectsare oftenmuchworse. More informationabout Mykayla’sexperience canbe foundhere: http://www.bravemykayla.com/Her_Treatment.html
  • 35. 35 As of February2014, Mykayla continuestodoverywell,andhasbeenincreasinglyfeaturedinthe media. One suchinterview onVice.comhasreceivedalmosttwomillionviews (http://www.youtube.com/watch?v=TXKjRkkoIOU). The interview alsofeaturedStoneyGirl Gardens and the workof Frankie andErin Wallace,whoare discussedlater. Erin Purchase waspromptedtouse cannabisoil to helptreatMykayla’scancerbecause of the experience of anotherchildpatient,CashHyde. Cash’sstoryhasbeencoveredbyseveral newsoutlets and hishistorywas deeply explored inthe documentary American Drug War2: CannabisDestiny. On May 3rd , 2010, Cashwas diagnosedwithaStage IV braintumor. On May 5th , surgerywas performed,andhigh-dose chemotherapybegan. The Hydes,Mike andKalli, were toldthatevenwith bone marrowtransplants,Cashhad an 80% chance of dying. The combinationof chemotherapyand otherpharmaceuticalsresultedina2-weekICUstay,where the Hydeswere warnedof possibleorgan
  • 36. 36 failure andbrainfailure. Asthe documentarygraphically depicts,Cash’sstate wasmorbidlysevere,and it isfranklystunninghowhe wasable tosurvive forso longthroughsomuch. In theirsearchto findsome wayto help theirson,the Hydesdiscoveredstoriesof cannabisoil healing cancer. The day of thisdiscovery,theymanagedtoacquire oil,andMike immediatelybegan sneakingit intoCash’sfeedingtube withoutthe doctorsknowing. Almostinstantly,Cashstartedtodrastically improve. Withintwoweeks,he wasable togetoff eightmedications,andhe startedtoeatand laugh again. His qualityof life changedcompletelyforthe better. Cashwasreleasedfromthe ICUinmid- December2010. His parentsbeganteachinghimhow tocrawl and walkagain,as hismotorskillshad markedlydecreasedasaresultof the cancer ordeal. InJanuary,brain scansrevealedCashwascancer free. Afterthe scans,Mike revealedtothe doctorsthat he had beensecretlyfeedingCashcannabisoil. The doctors were speechless,andthenattributedthe healingtoprayersratherthancannabisoil. As Mike said,"I believeinprayersand miracles,butIalsobelieveinnumbers,andatthe endof the dayit adds up." Nonetheless,hospital staff gatheredtowitnessCashleavingcancerfree,believingtheyhad seena miracle.
  • 37. 37 Giventhe potential forarecurrence,the Hydescontinuedtoprovide Cashwithcannabisoil afterthe remissionnews. However,inMarch 2011, a seriesof federal raidsonmedicinal cannabissuppliers resultedinCash’soil supplybeingcutoff. Theyran outof medicine inJune. InOctober2011, a scan confirmedthe Hydes’worstfear- Cash’scancer hadreturned. Theycouldnot reestablishasolid cannabisoil supplierinMontana,andwenttoCaliforniainNovember2011 to attemptprotontherapy. Theyalsohopedto finda cannabisoil supplierinCalifornia,andgetCash restartedonthe medicine as soonas possible. UponarrivinginCalifornia,doctorsreaffirmedapoorprognosisforCash,and said there wasno hope of shrinkingthe tumor. In December2011, the Hydeswere putin contact with Ringo,a producerwhogave thema 90-day supplyof cannabisoil forfree. Withthe combinationof protontherapyand cannabisoil,Cashwentintoremissionforasecondtime inJanuary2012. Mike remarkedthatCash wasthe firstcancerpatientto go through30 roundsof protonradiationtreatment withoutusinganynauseaor painmedicationbesidescannabisoil. Afterrunningoutof oil,the Hydesagainwere notable to finda sustainable supply. Andagain, inJuly2012, Cash’scancer returnedforthe thirdand final time. Thisthirdfightwasultimatelytoomuch for a childsoyoung,and Cash passedawayNovember14th , 2012 inMike’sarms,a final momentthe Hydesare thankful for. Hadhe died inthe hospital whileunderthe influence of several powerful pharmaceutical drugs,the passingsurelywouldnothave beenaspeaceful. Toshare Cash’sstory and informationaboutthe healingeffectsof cannabisoil,the Hydesstartedthe CashHyde Foundation (http://www.cashhydefoundation.com/).
  • 38. 38 In the November2013 issue of DOPE Magazine,the storyof SilasTedescowasdescribed (http://issuu.com/dlistmagazine/docs/dope_nov13_web_). SilaswasdiagnosedwithPrecursorBacute lymphoblasticleukemia,andsoonbeganchemotherapy. The treatmentswereveryharshandcaused general sickness,insomnia,andanearlyeight-weekperiodof immobility. Silas’doctorthen recommendedhigh-CBDcannabisoil. Asthe article concludes, “Afteronlyeightdaysoncannabis,Silasbegantowalk,talk,smile andplayagain.Itwas a complete turnaround.Silasisnowinremissionandrunningaroundlikeanaverage two-yearold. His leukemiaisinremissionandisshowingimprovementseveryday.” There are several othernotable childpatients,includingCharlotte Figi,JaydenDavid,and LandonRiddle,whoare discussedinthe Doctor and Team Operations section. The most dramaticrecoveriesare those involvingterminal cancer- where apatientistoldthey are goingto die,and doctorscan offerno furthertraditional treatmenttohelp. Eveninthese cases, cannabisoil hasproveneffective. Corrie Yellandisone suchcase. Her self-toldfullstory andmedical documentationof herexperience withterminal anal canal cancercan be foundat http://cannabisnationradio.com/corrie-yelland. These documentsare alsodirectlyreplicatedbelowfor convenience.
  • 39. 39 Hi, My name's Corrie. I'm 55 years old. In May of 2007, I had a heart attack and subsequently had a double bypass . As a result of the heart surgery, for 4 plus years, I have been plagued with chronic debilitating pain from a maligned sternum and post sternotomy neuralgia/syndrome. I was ingesting copious amounts of various pain killers 24/7. They barely touched the pain. I spent my days in agony, waiting for evening so I could try to sleep. I took sleeping pills nightly in a futile attempt to escape the hell I was going through and failed miserably. Within 2 hours of taking the pills, I would awake in agony. Fast forward to July of 2011. Already coping with 2 spots of skin cancer on my collar bone, I was stunned when I was diagnosed with Anal Canal Cancer. (This is the same cancer that took Farrah Fawcett's life.) Following 2 surgeries, the doctor told me they did not get all the cancer and I would have to endure a regime of radiation treatments. I started researching what this would entail, and attended a intake meeting at the Cancer Clinic. I was informed that "this is the worst area of of the body to radiate", the radiation beam would hit both my coccyx and pubic bone potentially causing permanent damage." They would try not to hit my spine. Additionally, I would suffer 2nd and 3rd degree burns vaginally, rectally, across my buttocks, as well as my entire "nether regions", and there was a "good possibility" both my vagina and rectum would fuse shut from the burns and subsequent scaring. The list of both short and long term side effects was endless and horrendous, but you get the gist. I told the doctor, I needed time to think about it. His response was hostile, as he told me I had 2-4 months, possibly 6. He murmured something abut a "death wish" and walked out. One day someone sent me Rick Simpson's video, Run From The Cure. It took me days to get around to watching it, but when I did I was blown away. Here was this man, a seemingly super straight small town Nova Scotian, talking about these amazing results he had seen with in himself and other people taking Cannabis and curing themselves of a myriad of diseases including end stage cancers. After hearing what Rick had to say, and watching the testimonials in the video, I was feeling some hope for the first time. For 2 weeks I did nothing but research cannabis as a medicine. I was stunned by the sheer number of studies on Pub Med indicating that cannabis indeed has the capacity to heal. I started using cannabis 2 months ago as per Rick Simpson's protocol from his video. (He recommends starting out small, and slowly upping the dose so ones' body becomes accustomed to it, without being high constantly. As a person who hasn't smoked pot since my late teens, early 20's, the non high aspect appealed to me). I had huge hopes to cure my cancer, and embarked on my fight to live. As well as ingesting the cannabis oil, I topically applied it to 2 spots of skin cancer on my collar bone. Within 48 hours, there were visible changes. In just over a week, the 2 spots were completely gone. Elated, I continued ingesting the oil, in hopes it would work on the other cancer attacking my body. Nothing prepared me for what happened next. About 2 weeks into my regime, the pain in my
  • 40. 40 sternum, as well as the nerve pain had become almost non existent. You have to understand, I had resigned myself to a life sentence of pain and agony. It had been 4 years of pain that was with me 24/7 and never, in my wildest dreams, did I imagine I would be pain free ever again. I was able to stand up straight, the jolting pain so intense that it would cause me to cry out, ceased completely. I started to sleep through the night and stopped taking sleeping pills. I saw one of my doctors a couple of weeks ago and was thrilled to hear he believes there is a decrease in both the size and number of tumours. I know in my heart it is only a matter of time before I will be completely cured. Even the most skeptical of my friends comment on the visible changes in me. I have evolved from a pain wracked, hunched over, shuffling along individual, to a vibrant, high energy person. Even my complexion has improved. Before I started using cannabis, I typically took 10-15 Tylenol 3 a day, along with a smorgasbord of other drugs. Now, in a 24 hour period, a half a Tylenol 3 is all I need. I think it's understandable when I say I get very emotional when I think of how far I've come. Not only has cannabis changed my life, it is SAVING my life. P.S. When researching,I met a woman in Texas diagnosed with the same cancer that I have. Diagnosed at the same time, we felt fortunate to have found each other, as we were identical in every aspect. I. E. same age, same diagnostic procedure, same stage of the cancer with radiation recommended as treatment. She chose to have the radiation. I'm very sad to tell you she died 2 weeks ago, as a result of infection from radiation burns. She left behind a husband and 12 year old daughter. The above was written (March 2012) I continued ingesting the oil on a daily basis, slowly, ever so slowly increasing the amount I was taking. As well, I began filling gelatin capsules with a mixture of the cannabis oil and olive oil and inserting them rectally. I thought to myself, if the oil worked being applied directly to skin cancers, wounds etc. why wouldn't it work there? Get it closer to the source, get it closer to the problem area. At the end of May, I saw the doctor who first discovered my cancer. I was in the operating room for a non related problem. At the time, I was told he could no longer manually or visually detect any cancer. Elated, for the first time I dared to hope, that maybe, just MAYBE the cannabis oil was working. Because the cancer was not this particular doctor's area of expertise, I was hesitant to become too excited. I was no longer taking any pain killers and found myself thinking that if all the cannabis did was to hold it at bay, I would consider myself lucky. On September 20, 2012, I saw my specialist/surgeon, whom I had not seen for approximately 6 months. He examined me once, then a second time, and then a third time. My heart was pounding so loudly I could hear the whooshing in my ears. And then the news I had only dared to hope for. "It's gone! I can't find anything at all. If it wasn't for the scar tissue I would never have known you had ever had cancer." I was shaking, looking at him in disbelief. Tears streaming down
  • 41. 41 my face, I hugged him mumbling, "thank you, thankyou." He looked at me, "No, Thank YOU! You're the one that did this. You DID it Corrie! You pulled it off, you pulled it off! No doctor, CANNABIS OIL and I pulled it off! I received confirmation that the cancer is well and truly 100% confirmed to be gone. Doc. 1 is when I was first diagnosed. The doctor's explained to me that my tumours looked like cauliflowers. They had cut off the heads of these "cauliflowers" and now what was left and could be seen with the naked eye were stems and then of course roots. I had these both internally and externally. This is when I was told I would require radiation. Doc. 2 is my report to my GP from the specialist when I first saw him after not having seen him for a year. The report is results of what he could see, (or should I say NOT see :-) )This is the visit where he examined me 3 times, because he couldn't believe he couldn't find anything. :-) Doc. 3 is the result of my biopsy from approx. 14 mos. after the start of cannabis oil treatment.
  • 42. 42 Document 1
  • 43. 43 Document 2
  • 44. 44 Document 3
  • 45. 45 Anothernotable terminalcancersurvivorisJoanne Crowther,who directly providedthe authorof this reportwithherfull storyand medical documentation. Joanne spoke onthe stepsof the VancouverArt GalleryonAugust25th , 2013 to tell othersof herexperience. She isextremelypassionateaboutmaking cannabisextractmedicine available toeveryone.
  • 46. 46 Joanne wasdiagnosedwithlarge B-celllymphomainsummer2009. The lymphomawaseliminatedwith chemotherapyinFebruary2010. The treatmentcausedsignificant nausea,vomiting,febrile neutropenia(feverresultingfromabnormallylow white bloodcellcount),andpneumoniarequiring hospitalization. InMarch 2010, a brainMRI revealedseveral cancerouslesions. These were resolvedby April 2010 withwhole brainradiation,asindicatedbyapost-treatmentMRI. For a year-and-a-half,Joannewasdoingverywell,evenparticipatinginahalf-marathon. However,inNovember2011, a mass developedinherleftthigh. Doctorsremovedthe 3.2x 2.5cm mass,and determineditwasconsistentwith diffuselarge B-cellintravascularlymphoma. The removal of thismassdidnot eliminatethe lymphoma. InearlyJanuary2012, Joanne beganreceiving medicationstotreatcomplicationsof the cancer. Furthermore,anotherheadCTscan revealeda6mm cancer lesioninthe leftsuperiorpons. The testalso confirmed resolutionof the previouslesionsinthe rightthalamusand basal ganglia. Shortlyafterthe 3.2 x 2.5cm massexcision,Joanne noticedregrowth of some mass inthe same area. She receivedfive shotsof radiationinJanuaryforthe new growth. More scans inFebruary2012 revealednew adrenalcancerousnodules. Joanne begantakingthe chemotherapydrugscisplatinandcytabarine tocombatthe cancers. She was thenhospitalized betweenApril23rd ,2012 and May 3rd , 2012 due to acute renal failure andhepatitis,whichhad been inducedbycisplatinandcytabarine respectively. The complicationspermanentlyendedJoanne’s chemotherapyregiment,withchemotherapystoppinginlate April. Joanne wasthendiagnosedwith relapsedintravasculardiffuse large B-cell lymphoma,and leptomeningeal disease. Withoutthe strengthto endure more chemotherapyorradiation,doctorscoulddonothing more,and Joanne wasforcedto try an alternative treatment. InearlyMay, she begantakingcannabis oil. She startedoff withsmall rice-grainsizeddoses,butafteraweek feltnoeffects. She thenupped herdosage to a gram of oil a day, andwithintwoweeksnoticedbeneficial effects –ingeneral,feeling betterandhavingmore appetite. OnJuly30th , 2012, Joanne hada follow-upexamination. The documentationresultingfromthe examinationisbelow. Itdescribeshow Joanne isdoingmuchbetter since beingoff chemotherapy,andthatthe leftthighmass“actuallyregressedspontaneously.”
  • 47. 47 AnotherexamfromSeptember24th ,2012 statesJoanne isnow inremission. The reportalsonotesthat she had beentakingregularhempoil supplements(referringtocannabisoil,nothempseedoil).
  • 48. 48
  • 49. 49 Furtherdocumentationof Joanne’sfinal appointmentsis recordedbelow. There are afew key thingsto note. Firstoff,there isan error inthe line,“She istakingcertainorganicoils,whichrobherof appetite, accordingto the patient.” Uponinquiryof thisoddstatement,Joanne informedthe authorthiswasan error,and she had actuallysaidithelpedherappetite,butforsome reasonitwas incorrectly recorded. These documentsalsoincludethe recordof Joanne beingtoldshe waslookingata palliative situation afterabandoningchemotherapy. Finally,andmostimportantly,theyrecordherclinical remission,with Dr. JohnW. S. Yun stating,“She made miraculousrecoverywithstableclinical conditionwithnofurther cranial nerve palsy.”
  • 50. 50
  • 51. 51 In late January,2014, Joanne appearedonCBC Newsspeakingaboutherstoryandthe new Canadian medical marijuanaregulations (http://www.youtube.com/watch?v=PejeP7GFEg0).
  • 52. 52 A case close to the cannabispolicyreformmovementasa whole isthatof Michelle Aldrich. Michelle has workedindrugpolicy reformforseveral decadesandisa well-knownfigure. Recently,inthe Winter/Spring2013 issue of O’Shaughnessy’s –TheJournalof Cannabisin Clinical Practice,Michelle told herstory (http://www.beyondthc.com/wp-content/uploads/2013/03/Michelle-BTHC.pdf). Hercancer experience ultimatelybeganNovember15th , 2011, whenMichelle missedalunchappointmentbecause she felttoosick. On November22nd ,Michelle wenttothe doctor,where she wasevaluatedbya physician’sassistantnamedSallyHolland. Michelle receivedachestx-rayandwas givenantibioticsfor bronchitis,althoughthe followingdaySallycalledMichelle toinformhershe hadpneumonia. Michelle returnedonNovember30th ,whenshe wastoldshe had a growthon herrightlung. Overthe next couple months,Michellewent toseveral appointmentstodetermineasoliddiagnosis. A CT scan on December23rd revealeda23 x 28mm tumor. A growthon the leftkidneywasalsoobserved. On January12th , 2012, Michelle wasnotifiedbyDr.Gary Feldman,herprimarycare physician,thather cancer waspoorlydifferentiatednon-smallcell adenocarcinoma. Michelleimmediatelystartedreaching out to friendsforsupport,andwas calledbyDr. DonaldAbrams,a long-time friend. Dr.Abrams appearedinthe documentary American Drug War2, discussedabove inthe storyaboutCashHyde,to talkabout medicinal cannabis. Dr.Andrew Weil,alsoafriendof Michelle,offeredherhelpandsupport. These people,combinedwithotherreferredoncologists,were Michelle’s“dreamteam”. In mid-January,Michellespoke withJeannie Herer,widow of the late JackHerer,one of the mostwell-knowncannabis activistsinhistory. Towardsthe endof hislife,Jackhadactuallybecome a majorsupporterof Rick Simpson. JeannietoldMichelle tobeginusing“RickSimpsonoil”toassistwith treatment. Michelle acquiredanextractfromValerie Corral,founderof the Wo/Men’sAlliance for Medical Marijuana. Valerie callshermedicine “Milagrooil”,withmilagrobeingSpanishformiracle. Michelle receivedthe firstbatchof milagrooil onJanuary21st , 2012. Three days later,a PET scan showedMichelle’stumorhadgrownto30 x 31mm, whichcouldhave eitherbeena“betterpicture”or the tumor had reallygrown. AfteraJanuary25th endobronchioscopic ultrasoundfine-needleaspirationbiopsy,the final diagnosiswas “Stage 3A poorlydifferentiatednon- small cell metastaticadenocarcinomaof the rightlungwithbulkylymphnode involvement. Atleast three of the lymphnodeswere cancerous.” OnFebruary1st , Michelle hadherfinal test,acolonoscopy, inwhichthree polypswere removed,andaninflammatorycolonissue knownas diverticulitis wasalso identified. Michelle thenprogressedthroughtreatmentwithacombinationof chemotherapyand milagrooil. She initiallydilutedthe cannabisoil withhempseedoil,until eventuallyshe wastakingpure, unadulteratedcannabisoil. She hadfourchemotherapysessions,the lastof whichwasApril 5th ,2012. She finishedhercannabisoil treatmentonMay16th . Throughouthertreatment,Michelle experiencedcomplications fromchemotherapy,suchas nauseaand foodtastingstrange. Eventually,evendrinkingwaterburnedhermouth. Itwasnot until the beginningof Julythatshe couldeatproperlyagain. Thankfully,anApril 17th CT scan showedthe tumor hadreduced50%, and the lymphnodeswere significantlyreducedaswell. The scanalso showed the diverticulitis haddisappeared. AsMichellestated,“Chemodoesnottouchdiverticulitis…ithadto be the oil thathealedit.” On May 10th , Michelle receivedaPETscan, whichreported“virtuallycompleteresolutionof the tumor”. OnMay 18th , Michelle’ssurgeon,Dr.PeterAnastassiou,removedsixlymphnodesandthe 2.5cm remainsof the tumor,whichactuallywasjustdeadcancer tissue. Michelle furtherendured
  • 53. 53 complicationsfromthe surgeryandhadto remaininthe hospital,butwasfinallydischargedMay31st . Michelle reportsthatina conversationwithDr.Anastassiou,he saidhe had“neverseenlungcancer totallyeradicatedbychemo,muchlessinfourmonths.” Michelle believesitwascannabisoil thatmade the difference. ThroughoutJune,Michellerecoveredfromherordeal,andinJulyshe begantosteadily recoverenergyandappetite. Michelle finishedthe articlewiththe followingstatement: “I trulybelieve thatif itwasn’tforValerie andthe oil Iwouldnotbe alive today. EverydayI read about people dyingof cancerandI knowI was able to heal mybodyof cancer. Why is thishealth-givingplant not available toeveryone? Peopleshouldnothave togo throughthe sufferingthatcancerbrings. We needtoget thisinformationouttothe world. Cannabisisa healingplantandcan evenheal cancerif we letit.” An interviewwithMichelleaboutherexperience canbe foundhere: http://www.youtube.com/watch?v=9AZU-brG7i4 Mark Pedersenof CannabisPatientNetworkrecordedanexperiencewithJeremyKigar,ahospital dietician (https://www.youtube.com/watch?v=CJ-V-2RvSr8). Jeremy discussedhisexperience taking cannabisoil fora Grade IV astrocytomaof the cerebellum. Afterdiagnosis,he wasquickly startedon16 medications,includingantibiotics,antidepressants,narcotics,andmore. Afterlearningaboutcannabis oil,Jeremystartedbytakinga half grama day forthree weeks. Withinfivedays,significantchangeshad beenobservedinhisoverallwellness. Pharmaceuticalswere reduced,including eradication of opiates and antidepressants. Jeremyhasdeniedfurtherchemotherapyandusescannabisoil in90-daycycles, whichhas hiscancer undercontrol. Accordingtothe videodescription,itwasonlyafterbeginninghigh- THC cannabisoil that Jeremy’stumorbegantoshrink. Atthe time of filming,the tumorhasreduced fromGrade IV to Grade II.
  • 54. 54 A videofeaturingClarkFrench,anactivist withNORMLUK, describeshow cannabis oil made amassive difference to hismultiplesclerosis (http://www.youtube.com/watch?v=kdI8sGPia5s). He wentto Californiaforfour-and-a-half months,where he obtainedamedicinal cannabisrecommendationand begantakingcannabisoil. The treatmentwasincrediblyeffective –he no longerneedsawalkingstick and feelssomuchbetterthanbefore. In January2014, ClarkappearedonSkyNews,a UK newsorganization,todiscusscannabislegalization. He continuestouse cannabisashis onlymedication andcontinuestobe independentof wheelchairs and walkingsticks(http://www.youtube.com/watch?v=6dU5mRIrYUw). AnotherMS patient,Marcel Gignac, usedcannabisextractsto recoveralmostcompletely (http://medireview.com/2014/01/why-ms-patient-marcel-gignac-needs-30-grams-of-medical- marijuana-every-day). Hisformof the disease wasespeciallysevere,andMarcel enduredhundredsof medical teststryingtogetan official diagnosis. From2008 to 2013, hisconditioncontinuedtoworsen,
  • 55. 55 althoughsmokingcannabisandsurgeryhelpedbriefly. Atone point,doctorssaidhe wouldn’tlastuntil Christmas2011. He survivedwell pastthatpoint,andinMarch 2013 decidedtoincrease hiscannabis intake insteadof takingmore narcotics. Thisincrease consistedof takingamixture of hempseedoil withpure cannabisextractand liquidVitaminD,whichquicklyresultedinhisconditionimproving. To the present,he continuestogetbetter. Asthe article states,“Evenwheneverydoctortoldhimhe wouldnotsurvive,Gignacdefiedthe oddsthankstomarijuana. Now he wantseveryone toknow his story.” Marcel isalsostudyingNeuropharmacologyatMIT to learnmore aboutthe science of cannabinoidsatthe cellularlevel. PeterGermainrecountedhis powerful experience of overcomingType IIdiabetesandobesitywiththe use of cannabis oil inan August2012 video(http://www.youtube.com/watch?v=2v76PwzYr3w). His transformationwasremarkable. Withinayear,hisdiabetes andweightwere completelyundercontrol.
  • 56. 56 At the CannabisOil CuresCancerConcert,an event designed topromote the healingeffectsof oil,Amy Jo Clarkrecountedherhealingstory. She wasdiagnosedwithabraintumor,andin the absence of pharmaceuticalstreatedherselfwithcannabisoil. The turnaroundwasremarkable,andbloodwork takenjusta fewweeksaftertreatmentindicatednocancermarkers. Moreover,Amy’sphysical conditionandqualityof life improveddramatically. A May 2013 videodetailsEliasCooper’sexperiencewithoil forthe treatmentof chroniclymphocytic leukemia(https://www.youtube.com/watch?v=HU46L_nNKXM). Once diagnosedwithCLL,Elias desperatelywantedtoavoidchemotherapy,asitsoundedscarytogo through. His doctors saidas long as hiswhite bloodcell countremainedunderacertainlevel,theycouldpostpone chemotherapy. Elias didn’ttake anyspecial measurestocounterthe canceruntil hiswhite bloodcell countgothighenough to where chemotherapywasbecominganoption. Itwasthenalternative methodswere researched, and Eliascame upon the storyof Brave Mykayla,discussedabove. The storywascompellingenoughfor
  • 57. 57 himto try cannabisoil. Afterthree anda half weeksof takinghomemade cannabisoileveryday, producedbyhiswife Debra,Eliaswenttothe doctor for a bloodtest. Hiswhite bloodcell counthad dropped40,000, whichwas “life changingnews”. Noothertreatments,includingchemotherapyor pharmaceuticals,were used. While hiscase isnotcompletely resolvedyet, Eliassayshe absolutelydoes not see chemotherapyinhisfuture,anditisclear the cannabisoil ishavinga positive effect. Eliasprovidedanupdate onNovember17th ,2013 (https://www.youtube.com/watch?v=QTPoc_xSlnw). Interestingly,the detailsof hiscase correlate stronglywiththe studyin CaseReportsin Oncology (summarizedinthe OverviewofSupportingScience section),whichalsoinvolvedaleukemiapatient. As Eliasdescribes,hisbloodcountwentupduringtimeshe wasnotusing cannabis oil or wasusingless potentoil,butwhenhe againprocuredhigh-qualityhigh-THCoil,the countfell dramatically. Inthe journal case,the patientalso experienced increasesanddecreasesincancercell levelsunder similar circumstances. Forexample,whendosingwaslimitedtotwice aday,the patient’sleukemicblastcount rose slightly,butthenfell backdownsharplyafterdosingreturnedtothree timesaday.
  • 58. 58 A January2014 story ona Croationnewsstationdetailedthe storyof a38 yearoldman, referredtoas Mark forconfidentiallyreasons,fightingnon-small celllungcancer (http://www.youtube.com/watch?v=DVTkSKBeET4).He wasgivenfourtosix monthsto live,witha maximumof twelve monthsif fortunate. Mark initiallyusedchemotherapyandradiation,whichlefthim ina state that “youcan notevencall human.” His face was destroyed,hisupperlipswollen,tissuewas fallingoff hisfingers,andhisskinwasoverlysoft. The painwasespeciallydevastating,andthree timesa day,Mark thoughtof killinghimself. Despitethe barrage of conventionaltreatments,afurthermedical checkrevealedthe cancerhaddoubled. Afterthe news,Markstoppedthe treatmentsandbeganusing cannabisoil. He immediatelybeganfeelingbetter,andearlierpainsdisappeared.A monthinto treatment,Mark beganspittingout sizable amountsdarkmatterwhichwasconfirmedascancerous. Afterthree months,the cancerwasno longervisible onX-rays. Debbie Wilson’sexperiencewithcannabisextractsformultipletraumaticbraininjuriesillustratesthe benefitsof cannabinoidsforbrainhealing. Herstoryis extensively detailedinanarticle writtenbythe author (http://www.medicaljane.com/2014/02/24/the-story-of-debbie-wilson-how-cannabis-helped- her-treat-trauma-induced-epilepsy/). Epilepsy,dementia,migraines,pain,anddepressionwere Debbie’smainsymptoms,andforover20 yearsshe battledthese conditions. Itwasnotuntil 2010 that Debbie foundsignificantrelief insmokedmedicinalcannabis,whichstoppedherdiarrhea,stabilizedher bloodsugarand serotoninlevels,andreducedherseizuresandmigraines. Mostrecently,whenDebbie beganusinghigh-cannabidiol andTHC-acidtincture,herimprovementshave becomeevenmore dramatic,includingcessationof all five typesof seizuresshe experiencedbefore. A recentFacebook postfurtherdescribesthe incredibleprogress.
  • 59. 59 Spencerisa youngchildwhowas diagnosedwithdiffusepilocyticastrocytomainFebruary2013, after large tumorson the pineal gland,brainstem, andspine were foundinaJanuarydoctor’svisit. These detailsandthose followingare fromthe author’sconversationwithSpencer’smother,Suzetta. The radiologistgave Spencertwoweekstolive withoutsurgery,ortwomonthswithit. The radiologist’s reportsaidthe case was challengingtointerpretbecause Spencer’sbiopsytissue showedmarkersfor multiple typesof cancersof differentgrades. Inlate March, Spencerstarted the carboplatinand vincristine chemotherapeuticagents,whichhadhorrificside effects,includinganear-fatal allergic reactiononMay 20, 2013. In June,Spencergota legal medicinal cannabisrecommendation. His doctorssaid he was terminal inmid-July,andrecommendednofurthertraditional treatment. Itwas aroundthenSpencerbeganhigh-CBDoil (althoughitstillcontainedasizable amountof THCas well), whichhe usedfromJune until August. The oil hasdrasticallyimprovedSpencer’smobility, andhe is evenmovinghisarmsagain,whichdoctorssaidwas impossible becauseof priornerve damage. An October2013 MRI showedreductioninthe pineal glandandspine tumors,althoughothertumors remainedstagnant. However,leptomeningialdisease in the liningof Spencer’sbrainandspine disappeared. Since then,Spencerhascontinuouslyimprovedinall of hissymptoms,includingtumor size andmobility. Hisstorycan be followedat https://www.facebook.com/prayersforspencerjames516.
  • 60. 60 As of May 27th , 2014, Spenceriscontinuingtoimprove. A particularlyhigh-profilecase ongoinginSouthAfricaisthatof Mario Oriani-Ambrosini,aMemberof Parliament. Mariowasdiagnosed withterminalStage IV lungcancerinMay 2013 (http://www.iol.co.za/news/politics/ill-mp-to-introduce-dagga-bill-1.1649727). He denied chemotherapyinfavorof cannabisoil andbicarbonate of soda,anotheralternative cancertherapy,after beingtoldhe wouldn’tmake ittoChristmas2013. Mario haswell-outlivedhisprognosisandis feeling generallywell. Due tohispersonal successandhisbelief thatothersshouldhave the same opportunity, he has introducedabill legalizingthe medicinal andindustrialuse of cannabis. Marioalsowantsto set up a researchcenterforcannabisextracts,to determine the extentof the medicine’seffectiveness. Speakingtothe National AssemblyandPresidentJacobZuma,Mariomade an impassionedpleato decriminalize medicinal cannabis.“Iwastouchedto see the manI’ve knownandworkedwithformore than 20 yearsinthiscondition.I’ve askedthe ministerof healthtolookintothismatter,”President Jacob Zumasaid (http://www.iol.co.za/news/politics/zuma-notes-mp-s-call-for-medicinal-dagga- 1.1650592).
  • 61. 61 A furtherarticle aboutthe cannabisextractsituationinSouthAfricaopenedwithaquote fromLindsey Martin, a Cape Town motherwhotreatedherself for coloncancerwithoil (http://www.iol.co.za/news/politics/clamour-for-medical-marijuana-1.1651195).“There is nodoubt aboutit. My aggressive cancerisgone…the same cancer thatwas supposedtokill me inmonths.Iam alive todaybecause of cannabisoil.” Anotherpatient,amanwithMS namedGerdBader,saidhe was losingconsciousnessandclose todeathbefore usingextracts. Aftercannabistreatment,he sayshe has no more symptomsof MS, althoughsome mobilityissuesapparentlyremain. Experienceslikethese have ledthe CancerAssociationof SouthAfricatosupportthe developmentof cannabisextract medicines,aslongas theyare registeredwiththe properauthorities.
  • 62. 62 A personal lettersentfromapatienttothe blogMedical Marijuana411 detailstheirexperience of using ShonaBanda’svaporizationtechniquetoproduce oil and overcome severe symptomsof Crohn’sdisease (http://medicalmarijuana411.com/mmj411_v3/shona-banda-saved-my-life/).The writernotesthere is still more healingtogo,andprogressseemstohave beeninhibitedbyaninabilitytomake larger quantitiesof oil. Grow Goddess,whowasinitiallymentionedinthisreportasbeingJoe Crowe’scaregiver, describedhowshe came tostart producingoil andtreatingpatientsina poston HempOilHope.org (http://hempoilhope.org/viewtopic.php?f=5&t=124). She mentionsJoe’scase,aswell asa gout patient whoexperiencedconcrete successwithonlyafew dosesof oil. Grow Goddessstated, “Anotherpatient I have encounteredhassevere gout.He tookonlyafew dosesof the oil,andthe gout literally disappearedfromhisknuckles.Three monthslater,withouttakinganymore oil,the gouthadnot returnedtohisknucklesandthe gout onthe restof hisbodyisstill visible,butthe swellingwasreduced a bit.If he wentthroughthe full treatment,Ibelieve the goutwouldbe completelygone.” A November2012 post onthe forumGrassCity.comdetailedaman’streatmentof hiswife with self-madecannabisoil formetastaticbreastcancer (http://forum.grasscity.com/medical-marijuana- usage-applications/1130359-tumors-really-shrinking.html). The wife,givensix monthstolive after abandoningchemotherapyandradiation,begancannabisoil asanalternative. Withinthree days,she was able toeat again;her excruciatingheadachescompletelydisappeared,andshe begantolookbetter overall. Atthe time of the post,anothertestconductedby the oncologistconfirmedthe tumorswere actuallyshrinking. Interestingly,the manwasgiveninformationabout“RickSimpsonOil”fromGranny Storm Crow,the individualmentionedabove inthe OverviewofSupportingScience section who compiledandorganizedanextensivelistof studiesoncannabis.
  • 63. 63 AnotherpostonGrassCitydescribesacannabisoil user’spersonal experiencealongwiththatof hisfriend(http://forum.grasscity.com/medical-marijuana-usage-applications/664504-ingesting-rick- simpsons-hemp-oil.html). The posterindicatedthatbyconsuminga small amounteveryeveningbefore bed, hissleepimprovedsubstantially (whichwashisoriginal purpose fortryingthe oil). Hisenergyalso sharplyelevated. He sayshe no longergetshighanymore,evenwithconcentratedformsof smoked cannabis. The posteralsomentionshisfriend,whohadcancerinhisliverandpancreas and wastoldhe had onlysix monthstolive. Aftertwo monthsof takingcannabisoil,furthertestsbyhisdoctorcould not findanytrace of the cancers. A poston Natural-Newsrecountstwopositive Lyme diseaseexperiences,one withsmoked cannabisand anotherusingextracts,the latterof whichwasclearlymore effective (http://www.naturalnews.com/043834_cannabis_lyme_disease_medical_marijuana.html). The first patient,Alexis,wasdiagnosedwithlate-stage Lyme diseaseandprescribedalitanyof pharmaceuticals. Giventheirrelative ineffectiveness,she begansmokingcannabis,whichenabledhertoeatmore,sleep better,elevatemood,andreduce pain. “Inthe hospital,Ihave neededtohave morphine orlorazepam throughan IV toaccomplishwhatsmokingtwograms of cannabisdoesonthe comfortof my couch, ina fractionof the time,”saidAlexis. The nextpatient,ShellyWhite,alsohadasevere formof Lyme disease whichledtoat least10 seizuresdailyfor ayear and a half. Througha combinationof smokingand vaporizingcannabis,herseizuresstopped. Shellythenmovedontoingestingcannabisoil,which resultedinimmense benefitsafteronlyamonth. She returnedtoworkand school,andcan now move out onher ownand enjoyanormal social life. TwootherLyme disease patientswhousedcannabisoil successfully,PamelaBailyandLisaSikes,are alsomentioned,buttheircasesare notelaboratedupon. On GreenPassion.org,ausertoldof how well cannabistincture workedforgastroparesis,a conditionthatdelaysemptyingof the stomach (https://www.greenpassion.org/index.php?/topic/24369-tincture-for-gastroparesis-and-digestion- issues/). Thiscondition,alongwithastomach-relatedseizuredisorder,were “helpedimmenselyand instantaneouslybyusingthe marijuanatincture.” Anotheruserrespondedtothe threaddescribinghow cannamilkworkedwellfortheircase of gastroparesis. OnGrassCity.com, auserwitha rare formof gastroparesisdescribedhowjustsmokingcannabismakesherdigestionalmostnormal,whereaswhen not smokingshe cannotkeepanyfluidsdownandalsohasmore trouble eating (http://forum.grasscity.com/medical-marijuana-usage-applications/470168-medicinal-marijuana- gastroparesis.html). The incredible storyof StanRutner,featuredoniReadCulture.comonSeptember6th ,2013, describeshowhe beat metastasizedlungcancerwiththe importantassistance of cannabisoil (http://ireadculture.com/2013/09/news/flash/convinced-of-the-cure/). Initially,Stanreceivedchemotherapyandradiationtreatmentsforthe cancersinhislungsand brain. These treatmentsstartedinMarch 2011. BrainradiationendedJune 25th ,2011, and on July13th Stan enteredthe hospital forwithradiationpneumonitis(inflammationof the lungsdue toradiation therapy). Onthe last of three hospital visitsduringthisperiod,Stanwaskeptfora weekandputon oxygen24/7. The traditional treatmentswere apparentlyineffective. Stanenteredhospice onAugust 12th , and wasgivenlessthansix monthstolive. Withnoother traditional options,the Rutnerfamily lookedintoalternatives,andfoundcannabisextractstobe a potential solution. InearlyNovember 2011, Stanstartedtakingsmall dosesof cannabisoil-infusedcoconutoil inthe morning. Inlessthantwo
  • 64. 64 weeks,he wasable togive upthe extraoxygen. Stanstartedgainingweight,sleepingbetter,and gettingstronger. He continuedonthiscourse until January27th , 2013, whena brainMRI revealedthe cancer wasgone. The lungcancer wasapparentlygone aswell. Frombeinginhospice tobeinghealed, Stan’sexperience istrulyremarkable. Stan iscontinuingtodo well asof March 2014 (http://www.unitedpatientsgroup.com/blog/2014/03/20/dads-update-stan-rutner-a-cancer-survivor). His daughter,Corinne Malanca,isworkingwithJohnMalancaas part of UnitedPatientsGroup (UnitedPatientsGroup.com) tobringthismedicinetothe world. On November27th ,2013, a press release titled“Time toTell the TruthAboutCannabisforKidsWithCancer,Says UnitedPatientsGroup and CashHyde Foundation,”waspublished(http://www.prweb.com/releases/cannabis-kids- cancer/united-patients-group/prweb11374767.htm). The release announcedthe launchof anew pediatriccancerawarenessinitiative. JohnMalancastated, “One drop of cannabisoil can give these childreninstantrelief fromthe sufferingcausedbytheircondition,andacannabisregimencanstop the cancer fromgrowingaltogether,”Johnsaid.“It’stime forfacilitiesandfederal entitiestoacceptthe truth aboutcannabis,stopspreading misinformation,andgive familiesafightingchance.Ourphone ringsoff the hook dailywithcallsfromaroundthe world.Desperate familiesfromthe UK,Panama, Pakistaninadditiontothe U.S. reachout to us indire needof one lastchance.” A November9th ,2013 article describedthe workof Constance Finley (http://www.medicaljane.com/2013/11/09/success-stories-cannabis-oil-in-the-us/). She wasdiagnosed withankylosisspondylitis,whichisarthritisof the spine and sacroiliacjoints. Afterpharmaceuticals nearlyendedherlife,Constance learnedthatcannabismightbe able tohelp. She learnedhow togrow cannabisand produce high-qualityextractsatOaksterdamAcademy,thenbegantreatingherself and otherpatients. Afterusingcannabis,Constance’shealthnoticeablyimproved.Anoncologistlearnedof Constance’sworkandreferred26 Stage IV cancer patientstoher fortreatment. AccordingtoFinley,her cannabisoil helpedtreatthe cancerand keptall butone of the patientsalive. The authorof thisreport
  • 65. 65 spoke withFinley,whoclarifiedthatthe patients’oncologistshaddeclaredtheminremission. She also recountedherongoingsuccesswithtreatinglate-stage cancerpatients. A February26th , 2014 article on a local Fox affiliate toldof aSouthwestFloridamomcurrently usinga combinationof whole cannabisoil andisolatedcannabidiolforherchild. Withinhoursof giving herchildboth oils, the mothersaidthere was improvementinqualityof life (http://www.jrn.com/fox4now/news/Desperate-South-West-Florida-mom-turns-to-medical-marijuana- 247313011.html). Alsomentionedis DahliaBarnhart,whoisusingcannabisoil tofightbraincancer. Moriah Barnhart,Dahlia’smother,saiditisunfairshe had to move to Coloradotouse thismedicine,but that painisoutweighedbythe progressDahliahasmade. She ishappierandhealthier,and“if she had hair youwouldn’tknowshe wassick.” AnotherFox article aboutDahlia statedshe takesabouta gram perday of high-CBDoil,andMoriahsaid,“I saw almostimmediateresponsescognitively;she developed intoa normal 3-year-oldfroma verycriticallyill childalmostovernight" (http://www.myfoxtampabay.com/story/24514726/2014/01/22/family-moves-to-colorado-for-medical- marijuana-treatment). An April 29th , 2014 article fromthe female-orientedcannabismagazineLadybuddetailedthe particularly dramaticcase of LoganEwell,achildcancer patient(http://www.ladybud.com/2014/04/29/cannabis- versus-acute-lymphoblastic-leukemia-go-team-logan). LoganwasdiagnosedwithBcell acute lymphoblasticleukemiaonApril 16th ,2009, and beganchemotherapytreatment. Giventhatthe lymphoblastswere onlypresentinLogan’sbloodandbone marrow,aggressivetherapywasnotinitially needed. Whilechemotherapykeptthe canceratbay for twoyears,inMarch 2011 testsshowed lymphoblastshadnowspreadtoLogan’sspinal fluid,requiringanincrease inchemotherapyandthe additionof radiation. These treatmentsalsoapparentlykeptthe cancerundercontrol,until June 2013 whena secondrelapse occurred. InOctober,Loganwas admittedtoMott’s Children’sHospital to receive abone marrowtransplant,whichultimatelyprovedineffective. OnJanuary13th , 2014, doctors at the Universityof Michiganstatedthere were nomore options,andadvisedthe familyto seekout hospice care for the nextthree totwelve months.
  • 66. 66 Immediatelyafterhearingthe terminal diagnosis,Kimberly,Logan’smother,begantakingsteps to procure cannabisoil. She knewitwas an optionbuthadn’tseriouslyconsideredituntil there was nothingelse totry. The firstdose of only0.025 grams resultedinextreme sleepinessbutalsoquickly impactedthe lymphoblastcount,whichdroppedeightpercentinfourdays. Loganmaintaineda0.05 grams/daydosage until hisnextbloodtests,whichshowedrisingblastcounts. Kimberlythenobtained an oil seventimesmore concentrated,whichafteranotherfourdaysresultedinthe blastcountfalling again. On January28th , 2014, Logan washospitalizedforgraft-versus-hostdisease,atransplantation disorder. Hiscannabisoil dose wasincreasedto2 grams/dayduringhishospital stay,whichresultedin furtherreductioninlymphoblastcounts. However,Logan’sliverenzymesbecame abnormallyelevated, a potential resultof isopropyl-alcohol derivedcannabisoil. Afterswitchingto190-proof grain alcohol, Logan’sliverenzymesslowlynormalized; however, itisunknownwhetherthe solventwasthe actual cause. By April 2014, Logan was pronouncedcancerfree,andisquicklyrecoveringfrom the lingering side effectsof chemotherapy.
  • 67. 67 Giventhatall vertebrateshave endocannabinoidsystems,cannabisextractmedicine alsoworksin animals. A November22nd ,2013 article on CBSNewsYork describedthe experiencesof severalpeople whowere providingtheirdogswithcannabisoil (http://newyork.cbslocal.com/2013/11/22/seen-at-11- medical-marijuana-for-your-furry-friends/). RowynCapersdiscussedhow hisdogLunawas suffering immenselyfromlate-stage lymphomaandchemotherapy. He begangivinghercannabisoil incapsules, and sawthat as he increasedthe dosage,hersymptomsimproved. Vomitinganddiarrheastopped,and Luna was feelingbetteroverall. MaryLynn Mathre saidcannabisoil helpedwithherdog’scancerand was effective intreatingahotspoton anotherdog. Al Byrne saidthat all three of hisdogs remarkably improvedafterusingcannabisoil,includinganincrease inenergyand“shine intheireyes.” A February 26th , 2014 article onLadybud.comdescribedawoman’streatmentof hercat withcannabis-infusedolive oil and traditional cannabisoil (http://www.ladybud.com/2014/02/26/palliative-pet-care-using- cannabis/). The cannabistherapysignificantlyimprovedmobilityandappetite,andsubstantially reducedpain. The author,DiannaDonnelly,statedthatonce the strongeroil wasintroduced, apparentlygreaterrelief wasachieved. A Vice.comarticle detailsthe workof VeterinarianDougKramer andhiseffortstotreat animals withcannabisoil (http://www.vice.com/read/the-vet-who-wants-to-legalize-medical-marijuana-for- dogs-000841-v20n4). He describedthe use of cannabisoil forsickdogs,cats, andother animals. Anotherarticle featuresDr.Kramerdiscussingthe use of variouscannabisextractsfortreatingchronic arthritisincats and laminitisinahorse (http://www.naturalnews.com/044995_cannabis_pets_terminal_illness.html). A local college newspaperdiscussedthe historyof activistJonMarsh,now a leaderinthe cannabisextractmovement (http://laverne.edu/campus-times/2014/05/marsh-takes-medicinal- cannabis-to-new-high). He runsthe FacebookgroupCannabisOil SuccessStories,which currently has over26,000 members (https://www.facebook.com/groups/416702921703509). In the article,Jon discussedhowhe beganusingcannabistotreatGulf War Syndrome afterreturningfromOperation DesertStorm. “I can say that afternothingbutcannabisfor medicine overthe past20 years,my recent reportsfrombloodworkat the V.A.show me healthyascan be,”saidJon. He also voicedhisstrong supportfor usingcannabisextractstotreat cancer andotherdiseases,andiscontactingofficialsfrom Bermuda,Haiti,India,andJamaicaaboutsettingupcannabisextractsystems. Thisway,patientsfrom the UnitedStatesand the respective countrieswouldhave asafe place touse cannabisextracttherapy. Jonalso foundedThe CannabisConsultants,whichseekstoconnectinterestedpartieswithconsultants froma varietyof cannabis-relatedfields(http://www.thecannabisconsultants.com). The website also aimsto be a database of cannabisoil successes,aswell asdirectlyassistwithtreatment. A project knownas The Fortunate 500 endeavorstotreat500 cancer patientswithcannabisextracttherapy (http://www.thecannabisconsultants.com/fortunate-500.html). A remarkable case sharedfromThe CannabisConsultantsinvolvinglupusremissionisseen below(http://www.thecannabisconsultants.com/lupus-treated.html).
  • 68. 68
  • 69. 69 Many people have postedexperiencesonFacebook,eitherontheirownpagesor dedicated groups intendedforcollectingtestimonials. A varietyof screencapturedtestimonials are sharedbelow,with generallynomodificationsbesidesminorformatting.
  • 70. 70
  • 71. 71 Corrie Yelland,adocumentedcase mentioned inthissection,unsurprisinglymade averyjoyouspost uponfindingoutshe wascancer free.
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  • 91. 91 Alyssa’shusbandisMarkChavarria,a seasonedstuntmanwhohasworkedonfilmsincluding Inception, Iron Man,TerminatorSalvation,Machete,anddozensof othermoviesand televisionshows (http://www.imdb.com/name/nm0154459). In fact, he was eveninone of the author’sfavorite shows, Prison Break. Anexcellentarticle aboutMark’spathto stuntmangreatnessisfoundatthe Houston Chronicle (http://www.chron.com/life/article/Stuntman-Mark-Chavarria-put-his-body-on-the-line- 1607422.php).
  • 92. 92 The “I am, literally,livingproof”referstoSteve’sbattlewithpheochromocytoma (diagnosedin1968), a veryrare cancer whichtraditionallyhasa100% mortalityrate withinfive yearsforall patients. Steve claimsto have controlledthe conditionsolelywithcannabis. “Hisoriginal doctor,anexpertonthis conditionshockedtolearnhe wasstill alive,said,‘Insome amazingfashion,thismedicationhasnotonly controlledthe symptomsof the pheochromocytoma,butinmyview,hasarresteditsgrowth’” (http://en.wikipedia.org/wiki/Steve_Kubby).
  • 93. 93 Thissectioncontainsanimmense bodyof experiential evidence thatclearlydemonstratesthe beneficial propertiesof cannabisextracts. Lendingfurthercredibilitytothese testimonialsisthe fact that similar resultshave beenreplicatedbyformal institutionsandrespecteddoctors. Inthe followingsections, these activitieswillbe explored.
  • 94. 94 4. Corporate and Dispensary Operations It islargelybecause of the miraculousindividual results,alongwithcompelling science,that corporationsand medicinal cannabis dispensarieshave become involvedinthismovement. Perhapsone of the firstdispensariestouse cannabisoil forcancer wasthe LibertyBell Temple. The author recallstalkingtothe owneror an employee of LibertyBell backin2009, while tryingto informdispensariesof the benefitsof cannabisoil sotheywouldconsidertreatingpatientswithit. The persononthe phone statedthatLibertyBell wasalready usingcannabisoil totreatcancer,and it seemedtheyhadcome uponthisknowledge fromasource otherthan RickSimpson. LibertyBell Temple wasfoundedin2008 inHollywood,CaliforniabyRobertForchion,abone cancerpatientfrom NewJersey. Ina May 2012 article in The Trentonian,Forchionstated, “InCalifornia,Inotonlyuse medical marijuana,butit’sbeenshowntime andtime againtoshrinkthe size of mytumors,reduce the size of theirgrowth,anddoctors here have noissues withme usingmedical marijuana” (http://www.trentonian.com/article/TT/20120508/NEWS01/120509729). The Med Joint,a non-profitcommunity compassioncenterinOshtemo,Michigan,hasrecorded astoundingsuccesswiththe topical use of oil (http://mijoint.com/testimonials.html). Theirwebsitelists a wide varietyof remarkable successes,largelythroughthe use of non-psychoactive medicines.
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  • 96. 96 SynergyWellnessisaCalifornia-basednon-profitcollectivespecializinginhigh-CBDmedicine (http://synergycbd.com). Theyfeature numeroussuccessful reportsontheirwebsite,manyof which are excerptedbelow. The “Epilepsy”statementisfromthe collective,while the othertestimonialsare frompatientsthemselves.
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  • 98. 98 The Pot Lab, a non-profitcooperative,produceshigh-qualityorganiccannabisextractsandisdedicated to researchintotheireffects. Theyalsoproduce non-psychoactive extractssuchasTHC-A (THC-acid) tinctures. A recentsurveyintoeffectsof theirPurifiedTrichome Tincture revealedthe followingresults:
  • 99. 99 A surveyconductedbyThe PotLab throughsocial mediaresultedinthe followingdatasurrounding cannabisextracttreatmentforvariouscancers. CompassionNevadaConsultingisanorganizationhelpingpatientsgetlegal medicinal cannabiscards and acquire medicine. Theyalsoteachpatientstogrow cannabisanduse itproperly,includinginthe formof extracts. A recent “I-team”investigationinLasVegasrecountedthe storyof a mother,forced intoanonymitybecause of the illegal nature of heractions,who eliminatedterminal cancerinheryoung daughter(referredtoasMelissa) withoil (http://www.8newsnow.com/story/24657397/i-team-mother- turns-to-pot-to-save-daughters-life). The extractusedwasproducedbytwo anonymousindividualswho claimedthey’dseensuccess withliver,kidney,andlungcancer. Melissa’smotherwastoldbydoctors Melissawouldlive toamaximumof age three withradiationandchemotherapy. Those optionswere denied,andafteranundisclosedperiodof time using cannabistreatment,the cancercellsweredead. AdamSternberg,acancer survivorandfounderof CompassionNevadaConsulting,andwhoapparently consultedwiththe above case,stated he hasseenextracts“retardandcure cancer”. Adamalso stated, “It ishelpingdiabetics,Alzheimer's,dementia,multiplesclerosis,Parkinson'sdisease,all of these,I swearto God it helps.”
  • 100. 100 The GreenSolutionisa Denverdispensarywithrisinginvolvementinusingextractsforcancer. Most recently,aFebruary2014 article ona local ABC NewswebsitediscussedThe GreenSolution’sendeavor to raise moneyforJonahAllen,a2-year-oldpatientfightinginoperable braincancer (http://www.thedenverchannel.com/news/local-news/denver-medical-marijuana-dispensary-providing- cannabis-oil-for-toddler-with-brain-tumor02212014). Inadditiontoraisingmoney,The GreenSolutionis directly subsidizingthe costof the cannabisoil treatment. The dispensaryisownedbythe fourSpeidell brothers,whohope Jonah’scase will encourage more researchintoTHC/CBDtreatmentforcancer,as well asincrease assistance tofamiliesseekingsuchtreatment.
  • 101. 101 EpsilonApothecariesisaCalifornia-basedresearchentitydoingworkwithcannabisextractsandvarious diseases(http://www.facebook.com/EpsilonCo). ItisheadedbyDave Mapes,whohas been workingfor yearsto perfectcannabisextractionprocesses. He hasalsoachievedamazingresultswithpatients,and providedthe authorwiththe followingstatementregardinghisobservations. “Generallyspeaking,mycancersuccessrate to remissionis80%.To complete cancer"free"status,it's about60%. Thisis fromthe workon 18 stage II-IV cases,includingcolon,colorectal,liver,kidney, bladder,pancreas,multiple braintypes,tripnegbreast,prostate,lung,spine.I've workedmany individualcasesof disease....HIV,hepatitisc,wastingsyndrome,etc.Pediatricandadultepilepsy,be it geneticornon genetic,includingtraumaticbraininjuries...successrate is80%, measuredbyan85%+ reductioninobservedseizuresand95%+ reductionin documentedsubclinical activity. Chronicpain(includingneurogenicorigins) makesupthe largestnumberof casesItreat, followedbyCrohn/colitis,nonmalignanttumors,diabetes,anddermal disorders.Mychronicpain treatmentsuccessrate isabout 90%, measuredbysignificantandsatisfactoryimprovementof pain levelsANDfunctional improvement(includingmental attitude,psychresponse),asdeterminedbyeach patient.Neuropathymakesupthe majorityof paintype andismanagedwell viamysystematic approach.Crohnsand colitisare at about 85% successrate, as measuredbyflare upsandinflammation. Diabetesisgoingtobe part of newstudiesmovingforward,Idon'treallykeepmajorrecordsof those casesas they're verydifficulttoexamine. Nonmalignanttumorsare treatedVERY well...withnearly100% successrate,measuredby complete disappearance of the tumors.” One of Dave’smostsignificantaccomplishmentsisthe creationof a free guide abouthow to produce varioustypesof extracts,includinghigh-THCoilsandTHC-A tinctures. Itislocatedat EpsilonResearch.com. Dave alsorunsa THCA FacebookgroupwithMark Heinrich,asa wayto directly helppeople whohave questionsaboutextractproductionanduse (https://www.facebook.com/groups/wholeplanttherapies).
  • 102. 102 CannabisOutreachCollective isaPortland-basedorganizationspecializinginhigh-potencycannabis extracts(https://www.facebook.com/COC503). Itwas foundedbyFrankie andErinWallace,whohelped treat Brave Mykaylaand have assistednumerousotherpatientsaswell. The authorstayedwiththem for several daysin earlyMay andcan attestto theirremarkable dedicationandoperations. Belowisan image fromCOC’sFacebookpage and a picture of the author withthe Wallace’sdogChase.
  • 103. 103 RiverRock,a Denver,Coloradodispensary ,hasbeenleadingthe fieldof professional cannabisoil cancer treatment. Theyhave alsotreated othersevere conditionslike trigeminal neuralgia,the rare “suicide disease”discussedbyAamannDegarthinan earlierreferencedvideo. RiverRock recentlystartedtheirAdvanced CannabinoidTreatmentsprogram(A.C.T),inwhichtheyare documentingthe use of concentrated oils,mostlyof the high-cannabidiol variety,onmanykindsof diseases. AccordingtoRiverRock, “The RiverRockA.C.T.Programhasbeenprovingtobe extremely effectiveinfightingcancer,tumors,neuropathy,Crohn's,lupus,MS,fibromyalgia,seizures,rheumatoid arthritis,autoimmune disorders,chronicpain,nerve damage,degenerativebone disease,weightloss, and more.” One of the mostpopulartestimonials featuresJack,apatientwitha40-year historyof fighting skincancer (http://www.youtube.com/watch?v=0h4OHolsGNg). Forthe mostrecentdecade of this history,he’s hadto regularlysee adoctorfor surgical removal of continuallyreappearingskincancer lesions. Afterayear of being part of RiverRock,he talkedwithTony Verzura,aproprietorof the dispensary,aboutaplanto combat hisskincancer. They came up witha complete programthat includesteas,tinctures,capsules,oils,andraw juices. Withinamonth,hisskinhadimproved dramatically. Afteranothertwoweeks,he wentintohisthree-monthregularlyscheduledappointment, where normally he wouldhave lesionsexcisedorfroze off. Atthisappointment,forthe firsttime inat leasttenyears,the doctor foundnothingtoremove. Jack’scase isunique because itis apparently the firsttime skincancerhasbeentreatedso effectivelywithinternal treatment. Normally,conditionslikeskincancerare primarilytreatedtopically, but Jack’scase demonstratesthatevenhigh-dose internal treatmentalonecanwork. However,atthe endof the interview,Jacknoteshe doesuse small amountsof topical oil forrogue,singlespotsthat appear. He saysthat by puttingthe oil ontoa bandage and thenontothe spot, itdisappearsindays. He believescannabiscurescancerandhe’slivingproof.
  • 104. 104 The nextvideodescribesRegina’sexperience withpotential breastcancer (http://www.youtube.com/watch?v=I2uND41_LTE). Reginadiscoveredalumpinher leftbreast,which was initiallyasoftbulge thatgraduallybecame harder. InFebruary2013, Reginastarteddeveloping a smaller,harderlumpinherrightbreast,muchcloserunderherarm. It hadconcerningsigns. Regina had no health insurance,andthusnowayto get herconditionexaminedortreated. A friendof Regina’s whowas a nurse checkedher,andalso washighlyconcerned. ReginamovedtoDenverandqualifiedfor medical assistance; subsequently,she wasexaminedbyanurse practitioner. A mammogramwas recommendedbutnottaken. Aroundthe same time,Reginahadbeenlookingintosomethingforher health,andfoundRiverRock. She was intriguedbytheiruse of high-CBDoils,andbeganaprogramtwo daysbefore herappointmentwiththe nurse practitioner. Reginabegantakinginfusedcapsulesinthe daytime,alongwithjuicingcannabisandfull-strengthoil atnight. Aftertwoweeks,Regina thenwenttohermammogramappointment. She hadnotcheckedher lumpsduringthose twoweeksof treatment. Whenthe technicianaskedtoidentifythe lumps,Regina feltthe lumponher leftbreast,andit“feltlike jelly,itdidn’tfeel like alumpanymore.” Asshe feltfor the right side,she couldn’tfindanything. The techniciantookanumberof slidesthroughthe mammogram,andan ultrasoundwasalsotaken. The techniciancame backwitha doctor, andafter conversingwithRegina’snurse practitioneranddoinganotherultrasound,the 2cmlumpinthe right breastwas confirmedasgone. The lumpinthe leftbreastwasstatedas not beingabnormal,despite Reginatestifyingthatithad seemedabnormal initially(goingsofttohardto soft,thena little harder, thengone). Reginafeelsveryfortunate for participatinginthe high-CBDprogramandfeelsgreatin general. A December6th ,2013 follow-upmammogramrevealedthatReginaisstill doingwell,withthe doctor sayingherbreasttissue is“evenhealthier”whencomparedtothe resultsof aJune mammogram.
  • 105. 105 A retiredDenverBroncosfootball playernamedJace toldhisstoryinJanuary2013 of how cannabis medicine workedtoalleviate histrigeminal neuralgia (http://www.youtube.com/watch?v=D2Fe4ssYg7A). Jace’sfootball careerended afteranon-fieldinjury, whena linemanfellonhis leftshoulderandrippedoutall the cartilage fromthe socket.Jace laterfell off a crane from12 feethigh,landing onthe rightside of hisface. The injurycausedmassive damage,and reconstructive facial surgerywasrequired. He recoveredwithin40daysand returned towork remarkablyfast. However,Jace then begantoexperience chronicheadpain. He couldn’tfunction,yet was tryingto act like itwasn’tthere. He desperately neededtofindsome waytoimprove hisqualityof life. Manydoctors didnotwant to take hiscase on. Everythinghe wastrying,includingpowerful narcotic painpillslike fentanyl anddilaudid,werenotworking. The doctorgave Jace a transcutaneous electrical nerve stimulation (TENS) unittohelpwithtrigeminal neuralgia,whichapparentlyhad originatedfromthe crane fall. The unitprovideselectrical stimulationtonerves,apractice thatcan reduce pain. WhenJace firstbeganusing cannabisextractmedicine,he foundthe painrelieftobe miraculous. He describeshisexperienceassuch, “The firsttime Itook those [CBD/THCpills] IrippedthatTENSunitoff the back of myneck,it’son my nervesanyway,butitrelaxedme somuchit tookcare of mypainI didn’tfeel like Ineedediton.Andno narcotic hasever,evergivenme thateffect.” He saysalthoughthe lastfive yearshave beenmiserable, the last twoor three monthshave beengreatsince startingthe cannabinoidregiment,andhe hashis life back.
  • 106. 106 A patientnamedGaryrefusedchemotherapyforStage IIIcoloncancer,havingbeenthroughthe ordeal before,anddecidedtoresearchalternative healingmethods (http://www.youtube.com/watch?v=1HsvNkEbbf0). He foundcompellingevidenceonthe use of cannabisforcancer, and decidedtopursue the route. Gary andhis wife foundRiverRock,andhe began a 90-day treatmentprogram. The treatmentworkedincrediblywell internally,withGaryfeelingbetter than he had intenyears. Gary alsotriedcannabisoil topicallyfor askincancer on hishead,andin about two-and-a-half weeks,the lesion fell completelyoff. Underneathwascleanskin. Discolored,swollen anklesalsocompletelyresolved,aftertenyearsof presence. While nofurthermedical testsforthe coloncancer have beenrunsince Gary beganthistreatment,himandhiswife clearlysee the powerful benefitsexperience sofar,andhave no doubtintheirmindsthisiscuringhiscancer. A patientnamedJohnusedaRiverRock preparationknownas“PrivaPills”,whichcontainCBD, THC,and cannabinol (CBN),tocombata wide varietyof diagnoses,includingautism, andchronicshoulder,neck, and back pain (http://www.youtube.com/watch?v=Dzel_WcItU4). From11 to 19, Johnwasdrugged heavilyforhismental condition,atone pointbeingonsevenmedications. At19, he got off all the
  • 107. 107 medications,butenduredneuropathyandnerve damage inhis feetasa resultof the drugs. His stomachlininghadalsodeterioratedheavily,affectinghisappetite. Hissocialityalsodeclined. One of hisfriendsintroducedhimtocannabis,andusingitsubstantiallyimprovedall hissymptoms. He then advanced to learningaboutcannabidiol, andbeganingestinghighquantitiesof CBDsourcedfromRiver Rock. Withit, he wasable to avoidusinganypost-operativenarcoticsorotherdrugs aftera spinal surgery,whichisimpressive becauseof the usual severityof suchpost-operative pain. The videodoes not explore the effectsonautismextensively,butitisclearJohnis doingbetteroverall. The nextpatientdiscussed, Josh,hasBehcet’sdisease,aconditionwhichhe describesasa combination of multiplesclerosisandlupus (http://www.youtube.com/watch?v=2fNRcEPfxLI). Joshalsohasan extremelyrare disorderknown asStevens-Johnsonsyndrome,whichinterfereswithhisabilitytotake medications,andmore directlycausescelldeath,leadingtoseparationof the epidermisfromthe dermis. AsJoshput it,“Insteadof havingan allergicreaction,youlose yourskin.” Thus,the condition is verylife threatening. Despite the danger,he hastriedvirtuallyeverypotential autoimmune pharmaceutical available, all of which onlymade hisconditionworse. Years-longsteroiduse also thinnedouthisbones. Evencutting-edge treatmentslike interleukinblockersdidnothing,andcaused horrificside effects. Currently,Joshhasmanagedtocontrol his diseasesusingalmost100% cannabisproducts. Everyday, he consumesagood balance of THC and CBD. Consistentingestionof cannabis isfinally controllinghisdisease successfully,andeverydoctorJoshhasseen,including those fromNYU,Johns Hopkins,andUniversityof Colorado,agree hiscurrentstate isanabsolute miracle andthe only explanationishiscannabisusage.
  • 108. 108 A patientnamedSteve enduredyearsof painandaddictionasa resultof numerouscomplicationsfrom manysurgeries,apparentlyinitiallystemmingfromagastric bypasssurgery http://www.youtube.com/watch?v=oduv97XCv0U. Steve wasonextremelyheavydosagesof narcotics, includingfentanyl. Throughthe use of medicine fromRiverRock,he wasable toget off narcoticsin30 days. He usesa combinationof cannabisoilsandjuicesfromindicaand sativastrains. He refusesto take narcotics nowbecause of the complications. A July2013 videofeaturedWade,whosufferedfromparalysismainlyonhisrightside fromseveral strokesexperiencedduringsurgery(http://www.youtube.com/watch?v=lqzJhepDmIs). Throughthe use of RockBudder,RiverRock’sspecial type of cannabisbutter,Wade’sparalysisbegantodisappear,until he was able to gainthe majority of movementbackinhishands. The effectivenessof cannabisextracts for paralysisisespeciallyexciting,butunlike otherconditionsthisisanarea withcomparativelylittle experience. Once cannabisoil becomesgloballyavailable,testingitextensivelyonparalysiscaseswill be immediatelynecessary.
  • 109. 109 Karenis anotherof RiverRock’ssuccessfullytreatedcancerpatients (http://www.youtube.com/watch?v=0INZDzUfL4o). InApril 2011, Karen was diagnosedwithStage III breastcancer inher leftbreast. She wentthrougheighttreatmentsof chemotherapy,and endured several surgeries. InFebruary2012, Karenfoundoutthe cancer had become metastatic,spreadingto the breastbone,hipbone,liver,andlymphnodes,apparentlythusmakingitStage IV. Karenlearned aboutcannabisoil therapyfromher son,and eventuallymetTony,whotoldthemaboutthe Advanced CannabinoidTherapyprogram. OnMay 1st , Karenhad her firstappointmentwithRiverRock andbegan high-CBDtreatments. KarentrackedherprogresswithCA-15cancer antigentests,andnotedthat once she incorporatedthe cannabinoidtreatmentswithtraditionaltreatments,the bloodtestsdropped significantly. Towardsthe middleof the A.C.Tprogram, KarenstatesherCA-15 score was 25, and under 30 is the baseline foranormal person. The bloodtestshave remained below normal,andshe’smoving away fromtraditional treatment. She will remainonthe cannabinoidsforanother3-6monthsto see howshe feels. Interestinglyenough,whentalkingtoheroncologistaboutcannabisextractmedicine, the doctor thoughthealingcannabisoil wascalled,“Angel Tears”(mistakingitforPhoenixTears). Karen explainedtoherdoctorthe sophisticationof moderncannabisextractprograms,andthe doctorsaid she couldcontinue thistreatment. She alsoaskedif itwouldbe necessary tosignsomethingforrefusing furthertreatment,butthe oncologistsaiddoingsowasn’tnecessary,asshe was progressingwell.
  • 110. 110 Karenprovidedanupdate inan October16th , 2013 video (https://www.youtube.com/watch?v=ZSy2gvIHMs0).She reportedthe cancerwascompletelygone as determinedbyPETscan. “I killedStage IV cancerbyusingRiverRock’sA.C.T.Now program, andthe nutritional supportthatIgatheredformyself.” RiverRock hasothervideosavailableontheir “Learn”page,foundhere: http://www.riverrockcolorado.com/learn.php Harborside HealthCenter,the largestdispensaryinthe UnitedStates,suppliescannabisextractsfora wide varietyof uses. The owner,StephenDeAngelo,isone of the mostwell-knownU.S.activists,and has foughtdirectlyagainstthe Federal governmenttocontinue providing cannabismedicine. He appearsin Run Fromthe Cure2, the sequel toRickSimpson’soriginaldocumentary,discussingextract medicine (http://www.youtube.com/watch?v=Qv8yxuv6e1w). Ina clipfromthe trailer,he made the
  • 111. 111 followingstatement, “We have skincancerpatientswhoare comingtoHarborside everyweek.They take the oil,theyputthe oil ontheirlesions,the lesionsstopgrowingimmediately.” StoneyGirl Gardensisa medical collectiveoperatingoutof Oregon (http://gro4me.com). Theywere briefly mentionedinthe Vice.cominterview of Brave Mykayla’sfamily,andappearalongsideMykaylain the followingAustralianinterviewaswell (http://au.news.yahoo.com/nsw/video/watch/20712196/cannabis-success-for-young-cancer-patient). StoneyGirl isrun by Mike MullinsandJeniferValley,the latterof whomovercame terminal thyroid cancer withcannabisextracttreatment. Theyhave providedcannabisextractmedicine tomany patients,includingMykayla. Onthe Australiannewsshows,Mike stated,“Ohabsolutelythisdoescure cancer, we see itdaily.We’ve seenitinhundredsof patients.The childrenrespondextremelywell.”
  • 112. 112 AuntZelda’sisa California-basedorganizationthatprovidescannabisextractsandconsultswithpatients on optimal healingprotocols (http://www.azcannaoil.com). ItisheadedbyMara Gordonand Stewart Smith. Theyare particularly dedicatedtoproperdosingandtestingof extractmedicines. The author has spokenwithMara and Stewartat twoconferencesaboutthe successthey’veseenwithcannabis extractmedicine againstcancerandotherdiseases. The qualityof theirworkhasattractedsignificant attention,mostnotablyfromRicki Lake,formertalkshow hostandstar of the original 1988 Hairspray film. Ricki iscurrentlyproducingadocumentarycalled Weed thePeople,whichexaminesthe use of cannabisextractsto treatcancer, particularlyinchildren(https://movies.yahoo.com/news/how- cannabis-can-save-cancer-striken-kids--an-intro-to--weed-the-people---by-ricki-lake-165741433.html). The specificpatientsexaminedinclude Sophie RyanandChicoSmith,whohave opticpathwayglioma and rhabdomyosarcoma- respectively. Bothchildrenhave respondedextremelywelltocannabis extracttherapy,whichseeminglygreatlyenhancedthe anti-cancereffectsof the concurrent chemotherapywhile reducingside effects.
  • 113. 113
  • 114. 114 The projectcan be followedandsupportedat https://www.facebook.com/weedthepeoplemovie. ShamanicHealingisa California-basedcannabisorganizationdedicatedtoproducingthe highest-quality, spiritually-enhancedcannabismedicines. Theircannabisoil extractionprocesscanrequire uptosix monthsor more,and all ediblesare organic,glutenanddairyfree. ShamanicHealinghasobserved powerful healingeffectsfromtheiroils. Fromtheirinformationsheet:“Ourextractsandraw plant materialshave beenproventimeandtime againtocure unknownblooddiseasesthatwere deemed ‘untreatable’bydozensof specialistsovera20 yearperiod,reducedseizuresinchildrenfrom10 a week to one or two a weekinthe firstmonth,putStage 3 & 4 cancer as well asa verysevere case of Psoriasis intoremission,andmuchmore!” The organizationtakespride inbeingaholisticandorganicproviderof rare cannabismedicinesandhealthknowledge toall patientsinneed.
  • 115. 115 Heavens2 Betseyisa California-basedcollective specializinginhome deliveryof cannabismedicines. It was foundedbyJenniferRex-McCrayin2010. Jenniferhelpspatientsuse cannabisextractsforcancer and has writtenaboutthe subjectonherblog. “We are seeinganincrease of chronicallyill patientsjoiningourcollectivelookingforrelief orevena cure.The successstoriesandevidence of patientshealingisoverwhelmingandthe proof inthe science ishard to deny. Patientsare findingreductionandcell deathintumors,evenreportingremissionfromusinghighly concentratedCannabisOil alongwithothernatural supplements. Dependingonthe type andaggressivenessof the cancer,the aimisfor patientstoingestapproximately 1-3 grams of highlyconcentratedoil aday.Patientschoosingcannabistherapyworkuptotakinglarge dosesof the concentratedessentialoilsof Cannabis.” (http://heavens2betsey.com/cannabis-therapy- for-the-treatment-of-cancer). AnotherpostonHeavens2 Betseydetailsawoman’sexperience helpinghergrandmotherfight Stage IV breastcancer,whichhad metastasizedtoherlungsandthroat (http://heavens2betsey.com/spreading-awareness-through-research-not-selfies-my-grandmothers- battle-with-breast-cancer). Doctorssaidchemotherapycouldmanage the cancerandmaybe shrinkit, but the cancer wouldeventuallykillher. The patient’sgranddaughterhelpedhergrandmotherget startedon a combinationof concentratedoils,high-CBDlozenges,tinctures,edibles,topical,and vaporizedoils. Whenchemotherapywascompletedafterafew months,the patientwasplacedon estrogenblockersandanti-nauseamedications,while continuingthe oil. Shortlyaftershe underwenta newscan,whichsurprisedthe doctors – the largesttumor,aroundheresophagus,haddisappeared completelyandsmall nodulesremaininginherlungsappearedreducedinsize. Doctorsdeclaredthe patientinremission. The patient’sgranddaughternow fightstoraise awarenessof cannabis’legitimate anti-cancerpotential,andherpassionisclearlyarticulatedthroughherwriting. There are three prominentpublicly-tradedcorporationsinvolvedin the cannabisextractmovement – GW Pharmaceuticals, MedicalMarijuanaInc.,andCannabisScience. GWPharmaceuticals,asdiscussed
  • 116. 116 inthe OverviewofSupporting Science section,isconductingclinical trialsof cannabinoidsforepilepsy and braincancer, andholdsa patenton usingcannabinoidstotreatbraincancer. Theyuse the most traditional distributionchannelsandare workingcloselywiththe FDA togainapproval of theirextracts for variousconditions. MMI currentlyproduces awide varietyof cannabidiol-basedproducts,alongwithtraditional THC-infused medicines forregisteredpatientsinColorado. Subsidiariesof MMIinclude Dixie Botanicals, HempMedsPX,Phytosphere,andothers. MMI’s CBD concentratesare unique because of theirsource - industrialhemp,whichislegal and commonlyusedforclothesandtextiles. The industrial hempsource differentiatestheseextractsfrom high-CBDoilsdistributedby organizationslike RiverRock andthe latermentionedRealmof Caring Foundation,whoderivetheiroilsfrom non-hempcannabis strains. The cannabinoidprofile of industrial hempoil ismuch different,andbecause of theirrelativelylimiteduse,there isnotenoughresearchor experiential evidence tosaywhetherhemp concentratescanaffectdiseasesinthe same waysasnon- hemphigh-THCandhigh-CBDcannabis oils. Basedon the author’sconversationswithparentsof epilepticchildrenusingMMI productsand the followingdocumentedexperiences,itisclearthe hempCBD productsare deliveringsome kindof benefit. However,itisalsoclearthateither industrial hempoil ingeneral orMMI’sincarnationof industrial hempoil issignificantlyinferiortotraditional cannabisextractmedicine. The results,while still betterthanpharmaceuticals,are noton par withnon-hempoils. Moreover,there have beenclaimsbythe formerheadof Dixie Science,TamarWise,thatMMI productsare fraudulentandcomposedof low-qualityhemppaste (http://www.beyondthc.com/dixie- elixirs-unfit-for-human-consumption/). Dixierespondedtothe claimsbyprovidinglabtestsassuring qualityandquestioningMs.Wise’smotives (http://dixiebotanicals.com/lab-certified-quality/). Atthis time, the authorhas seennoconcrete evidence provingMs.Wise’sclaims. Inaddition,aparentthe author spoke withhadReal ScientificHempOil (RSHO),anMMI product, independentlytested to confirmcannabinoidcontent. However,thistestand otheravailable ones onlyindicate cannabinoid contentand notpesticide orsolventresidue,so contaminationpossibilitiescannotbe entirelyruledout. Afteranalyzingseveral testimonials,afinal statementonthisissue ispresentedbefore movingforward. First,the parentwhoprovidedthe authorwiththe independenttestpersonallyexplainedthe resultsshe isobservingwithherson. WithRSHO,he has eliminatedthe vastmajorityof pharmaceuticalsandreducedseizuresby90%. Previoustreatmentsincludedneurontin,keppra, depakote,klonopin,tegretol,zonegran,lyrica,brainsurgery,andseveral otherpills. Currently,the seizuresare almostentirelycontrolledwithjustRSHOandphenobarbital. A website calledHope4Harper.comdescribesthe experienceof ayounggirl withCDKL5 Disorder,whoisusing RSHOto control her seizures. Sofar,additionof RSHOto the current regimentof depakote (ananticonvulsantdrug) hassubstantiallyreducedHarper’sseizures. AnOctober17th , 2013 update providedthe followingseizure record (http://www.hope4harper.com/high-cbd-hemp-oil-week- 4-and-harper-dancing/). WeekPriorto StartingProduct:64 Seizures Week1 Using Product[RSHO]:28 Seizures Week2 Using Product:0 Seizures
  • 117. 117 Week3 Using Product:17 Seizures Week4 Using Product:11 Seizures As the recordshows,Harper’sseizure countdramaticallydecreased afterthe firstweekof treatment and thenrose againon weekthree,butdecreasedover35% betweenthenandweekfour. Comparedto herseizure countthe weekbefore treatment,heraverage seizure countthroughweekfourisnow 78.1% less. The cause of the temporaryreversal inprogressisunknown - because the dataisso limited, there hasnot beenenoughtime toidentifyatrend. However,basedonthe initial seizurecount reductionandotherpositive changes,the motherfeelsstronglythatthe medicine isworkingwell. An update onNovember18th ,2013 indicatedthatHarper’sseizureshadstartedtoincrease again,but still remainedbelowpre-RSHOlevels.Otherbenefitslikeimprovedinteractionandfeedback continued (http://www.hope4harper.com/2-months-on-industrial-hemp-cbd/). A December14th conversationbetweenthe authorandHarper’smotherindicatedthe seizureshave startedtodecline again,but still are notcompletelyeliminated. A man namedBrad Mossman,whohelpsdistributeMMI’slegal industrialhempCBDproducts throughhiswebsite PlantOfRenown.com,recently invitedanyone inthe SouthJerseyarea tocome directlytohishouse andtry CBD Vaporization(Vape) Oil forpainrelief. Like the Real ScientificHemp Oil,thisCBD extractisderivedfromindustrialhemp. VaporizingCBDoil offersnumerousbenefits, includingfast-actingpainrelief. The effectsof ingestinganykindof oil take time,butwithvaporization, the effectsare nearlyimmediate. There are alsoseeminglynodownsidestovaporizingCBD – there is no psychoactive high,nosmoke irritatingthe lungs,andthe benefitsof CBDare still delivered. Forlong- termuse and treatmentof seriousdisease,there’sno doubtthatoral ingestionis the preferred method, but CBD vaporizationmayprove tobe a useful adjuncttherapy. The authorrecallslungcancerpatients inthe pastwho vaporizedandingestedTHC-richcannabisoil topositiveeffect. Brad has postedthree videosof people who’ve takenhimuponhisoffertotry the CBD Vape Oil for pain. The firstvideo,postedOctober5th ,2013, featuresRaymond,a73-yearoldman whodescribes hisexperience lessthanfiveminutesaftertakingthree puffsof CBDoil froma vaporizerpen
  • 118. 118 (http://www.youtube.com/watch?v=dZozqcwaR1w). Asaresultof several surgeriesandteaching school ina fungal-infestedbuilding,conditionshave surfacedwhichcreate painall overhisbody,“from headto toe.” Upon arrivingto Brad’shouse,he had paininhisjoints,back,and knees. Afterthe three puffs,he feelsmore relaxed,lethargic,andhasmuchlesspain. Some painremainsinhisurinarytract, but he feelsthatmaydissipate aswell. Raymondhasspenttensof thousandsof dollarson pharmaceuticals,andseendozensof healthcare providers,withlittle lastingbenefit. Basedonthe resultsof justa fewinhalations of CBDoil,it’slikelythathispaincouldbe completelyeliminatedif he begana more complete program. Anothervideopostedthe same daydetailsSue’sexperience withthe CBDVape Oil (http://www.youtube.com/watch?v=5quw_8su1Hc). Sue’sconditionsinclude limitedmobility,three differentkindsof arthritis,andmultiple surgeries. Aftertryingthe oil,she didn’tneedtouse hercane or braces,and feels“100% better”betweenyesterdayandtoday. The videowastakenonhersecondtrial of the oil,asshe came back for more afterherpositive experience. Eachtime,she onlytooktwopuffs of the CBD oil. Withinfive totenminutes,she begantofeel beneficial effects. The pointsof painfelt better. Aftersevenyearsof dealingwithpain,Sue saysshe finallyfeelshopeful. She saysnothingelse she has triedhasworked,includingan$800 analgesiccream.
  • 119. 119 The third patientstory,alsopublishedOctober5th ,featuresTodd,the owner of a companycalledCrazy CleanRecoveryApparel (https://www.facebook.com/crazycleanapparel) thatmakesclothingforpeople inthe NarcoticsAnonymous program(http://www.youtube.com/watch?v=QKYlg7LjB3k). Toddhimself isa recoveredaddictandhaspainissues. Havingbeenformerlyaddictedtodrugs,Todd wantsto avoid narcotics,but still needsaneffectivewaytodeal withpain. He has a sciaticnerve problem, resultingin painin his lowerbackand downhisleg. Thispainaffectshisdailylife andsleep,withaverage painlevels between4and 6. Aftertakingthree puffsoff the CBDVape Oil,he feltitwithinminutes,andthe sciatic nerve painalmostcompletelywentaway. Toddfeelscomfortable withthisbecause of the nearnon- existentTHCcontent– he feelsit’sjustlike how he drinkshempmilkandeatshempseeds. Aswiththe otherpatients,he reportsnohigh. As these testimonialsindicate,severalpeople have experiencedlegitimate benefitsfromMMI’s industrial hempoil products. Thisshouldn’tbe surprising,giventhatlabtestshave confirmedhigh levelsof CBD. However, there remainsthe possibilitythatMs.Wise’s contamination allegationsare true. Such contaminationisone explanationof whythisisn’tworkingaswell astraditional cannabis
  • 120. 120 extracts. Anotherexplanationisthatindustrialhempoil ingeneral,whetherfromMMI or not,simply cannot achieve the same resultsastraditional cannabisextracts. Once properresearchcanbe conducted,these questionswill be answeredthroughscientificmethods. Researchandpropercontrols will notonlyilluminate these answers,buthelppreventanyfurtherreal orpotential abuse by corporationslike MMI. The author believesthatindustrialhempoil mayturnoutto be a supportive adjuncttherapyor functionwell asapreventative,butnoevidence suggestsitisoptimal forprimarytreatment. The nextcorporation,CannabisScience,isnoteworthyforitsworkwithskincancer. OnApril 6th , 2011, theyissuedapressrelease announcingtheyhadphysician’sdocumentationconfirmingthe successful treatmentof basal cell carcinomaresultingfromthe applicationof topical cannabisextract.
  • 121. 121 http://www.cannabisscience.com/index.php/news-media/news-archive/196-cannabis-science-provides- physician-s-documentation-that-confirms-successful-treatment-of-skin-cancer CannabisScience isnowworkingwithThe Phoenix TearsFoundationandNew ColombiaResourcesto conduct trialsof cannabisextractsforskincancer inColombia (http://www.marketwatch.com/story/new-colombia-resources-inc-enters-into-a-collaboration- agreement-with-the-phoenix-tears-foundation-for-research-and-development-of-a-cannabis-based- medicine-to-treat-skin-cancer-in-colombia-2014-05-09). This partnershipwillhopefullyprovethe efficacyof cannabisextractsagainstat leastone formof cancer once and for all,leadingtofurther research. The Phoenix TearsFoundation,headedbyJanetSweeney,wasinspiredbyRickSimpsonandis aggressivelytryingtoraise awarenessof cannabis’anti-cancerpotential. Tothisend,theyhave launchedThe Phoenix Five project,aninitiative totreatanddocumentfive patientswithadvanced cancers or tumors. Witnessingcannabisextracttherapyfromstarttofinishisthe mostpowerful indicatorof thismedicine’spotential. The resultswillultimatelybe sharedinadocumentarytitled Illegally Healed, butcurrentlytwoincredible patientupdateshave beenreleased.
  • 122. 122 GlendaDiltzwasdiagnosedwithStage IV colorectal cancer (https://www.youtube.com/watch?v=cD_cWTQzlTI). Asshe wentthroughthe oil treatmentfollowing apparentlyfailedchemotherapy,she couldfeelherbodyhealingandherenergyreturning. She felt normal again,herhair came back,her energycame back;it was like nightandday. While the statusof the cancer is notprovided, itisclearGlendaisexperiencingsome kindof progress. DavidAdkinswasdiagnosedwithaspinal tumorstretchingfromthe secondthoracicvertebrae tothe ninth. Aftersevenweeksoncannabisextracttherapy,the tumordisappeared. AsDavidstated,“Itdoes work.It’snot justthat it makesme feel better,it’stakencare of the problem, the tumor’sgone.We neverdida biopsytoknowwhetherthe tumorwascancerousor non-cancerous,buteitherwayitdidn’t matterbecause itwas growingina spot thatwas goingto paralyze me or kill me,andtheycan’tfindit now. So… there’snodoubtthat it works. Notonlydo I feel better,Isee the resultsonthe MRIs.”
  • 123. 123 The biotechnologyresearch organizationEmeraldBioisaimingtodevelopcannabinoiddrugstofight cancer. The CEO, JohanPontin,casuallyalludedtothe factthat cannabisextractswere alreadybeing usedto eliminatecancerinhumansina January2014 Boston Globe article (http://www.bostonglobe.com/opinion/2014/01/28/mass-puts-medical- marijuana/yr3vIP7R8sjIGQ3aqkdkPO/story.html). A segmentfromthe article states, “Pontin,whoappliedforalicense throughanoffshootcompany,saysit’snotjusta chance to ease the painof a couple of hundredcancerpatients.It’sachance to developnew drugsthatmightactuallycure cancer itself. That’s right.He says that caregiversinRhode Islandwho’vebeenworkingwithmarijuanaforyearshave beatenbackcancer withhighlyconcentratedoilsderivedfromcannabis. ‘There wasan 80-year-oldpatientwithesophaguscancer,’he said.‘Today,she is91 yearsoldand totally cancer-free.Eventhe insurance company couldn’tbelieve it.’”
  • 124. 124 An international biotechnologycompanycalledNuvilex,Inc.publishedapressrelease onFebruary3rd , 2014, announcingplanstodeveloplive-cellencapsulationtherapiesthatutilize cannabinoidstotreat cancer, viatheirsubsidiaryMedical MarijuanaSciences. (http://www.nuvilex.com/latest-news/89- nuvilex-to-use-proprietary-cell-in-a-box-technology-to-develop-marijuana-based-cancer-treatments). Dr. Mark L. Rabe, Chairmanof a Nuvilexsubsidiary’sScientificAdvisoryBoard,stated,“Reputable scientificjournalscontainnumerousreportsthatconfirmthe anti-cancerproperties of cannabinoids. Initial trialshave alsodocumentedthe effectivenessof treatingpancreaticcancerusingthe Cell-in-a- Box(TM) live-cell encapsulationtechnology.Whentakenalongwiththe factthatMedical Marijuana Sciences'parentcompany,Nuvilex,ownsthe exclusive worldwiderightstoutilizethistechnologyin developingcancertreatments,we believe thatMedical MarijuanaSciencesisinaunique positionto developcannabinoid-basedtreatmentsforcancerthatwill setitfar apart fromothersinthe medical marijuanaarena.” A May 9th , 2014 pressrelease announcedNuvilex/MMSwill workwiththe Universityof NorthernColoradotofurtherdeveloptheirencapsulationtechnologies (http://www.medicalmarijuanasciences.com/latest-news/129-nuvilex-signs-agreement-to-study- development-of-cannabis-based-cancer-treatments). These corporate and dispensary activitiescontributeverycompellinginformationtothe overall cannabisextractmovement. Itisbecause of these innovative organizationsthatavailabilityof cannabis extractmedicine hassubstantiallyincreased,allowingmore people accesstothe medicine theyneed now.
  • 125. 125 5. Doctor and Team Operations Several doctorshave beenmentionedthroughoutthisreport,includingDr.RobertMelamede. Dr. Melamede wassignificantlyinvolvedinthe skincancertreatmentproject of CannabisScience. He also has beenaleaderinendocannabinoidresearch,andhisideasare gainingmore supportasnew studies are conducted. In the fieldsof cannabinoid research,there are manydoctorswhoare especiallynotable. Dr.Donald Tashkinof the Universityof CaliforniaatLosAngelesconductedanotable studyconcludingthateven regular,heavysmokingof cannabisdoesnotleadtolungcancer. "We hypothesizedthatthere wouldbe a positive associationbetweenmarijuanause andlungcancer,andthat the associationwouldbe more positive withheavieruse,"he said."Whatwe foundinsteadwasnoassociationatall,andevena suggestionof some protectiveeffect." The original studyanda WashingtonPostarticle are found below: http://cebp.aacrjournals.org/content/15/10/1829.short http://www.washingtonpost.com/wp-dyn/content/article/2006/05/25/AR2006052501729.html An August2009 studyby researchersatBrown Universityfoundthatlong-termcannabis smokerswere about62% lesslikelytodevelopheadandnecksquamouscell carcinoma thannon- smokers. The original studyanda Fox Newsarticle are foundbelow: http://www.ncbi.nlm.nih.gov/pubmed/19638490 http://www.foxnews.com/story/2009/08/26/smoking-marijuana-regularly-may-reduce-risk-some-neck- head-cancers It isfrankly amazingthatjust smokingcannabisseemstooffersignificantprotective effects. Despite the factthat smokingisextremelyinefficientanddeliversonlysmall amountsof cannabinoids relative toorallyingestedextracts,itstillseemstoprotectagainstcancer inlimitedcircumstances. Of
  • 126. 126 course, forseriousprotective effects,andmostcertainlyforactual treatment,ingestionof extractsis required. Othermajor researchersincludeDr.SeanMcAllister,Dr.Manuel Guzmán, Dr.DonaldAbrams, and Dr. Raphael Mechoulam. All of theirworkshave contributedgreatlytomedicinalcannabis knowledge. However,unlike Dr.RobertMelamedeand Dr.WilliamCourtney,discussednext, theyhave not directlytreatedpatientswith cannabisoil anddonot necessarilybelieve thatcannabisextractscan cure cancer inhumans. It isthe author’shope that these researcherswilleventuallyunderstandthe true importance of theirwork,and benefitimmenselyfromthe intenselydetailedresearchtheyput theirlivesinto. Arguablythe mostimportantdoctorutilizingcannabisextractsinmedicineisDr.William Courtney. His workis veryunique because he worksprimarilywithjuicedcannabis. Thatis,Dr. Courtneyjuicesraw cannabisplantsalmostentirelywhole,andusesthe juice totreatpatients. The experiencesof his
  • 127. 127 patientshave demonstratedthatjuicingmaybe evenmore effective thancannabisoil,although the practice is certainly lessefficient. Dr. Courtney’sworkwasfirstdetailedextensivelyinthe documentary Leaf (http://www.youtube.com/watch?v=qa0nLdVJiIg). Itprimarilytellsthe storyof hiswife Kristenandhow she overcame lupusthroughcannabisjuicing. Kristen’shistoryof disease startedwhenshe was diagnosedwithjuvenilie rheumatoidarthritisat16, and diagnosedwithalupusconditionknownas interstitialcystitis(long-termchronicinflammationof the bladderwall). Itresultedinherbeing bedriddenforfouryears. She was onover40 medications,includingmethotrexate,alongwithpotent anti-inflammatories,painkillers,antibiotics,and steroids. Doctorssaidshe probablywouldnotmake it to 30, that she wouldneverhave children,andall theycoulddowastry to make hercomfortable with massive dosesof opiates. Kristenbecame aware of Dr.Courtney’sworkandbeganjuicingeveryday. Withinfourto six weeks of followingthispractice,herbackpainwasgone,she didn’tneedpainpills, and feltbetterthanshe hadin years. The treatmentapparently inducedremissionof mostmajor disease symptoms,andKristen nowhasa childandis living anormal life. Dr. Courtneybelievesthe benefitstojuicingare twofold. Cannabisjuice isnon-psychoactive,as the cannabinoidcontentappears primarilyinthe formsof THC-acidandCBD-acid, the non-decarboxylated formsof THC and CBD. Due to a lackof psychoactivity,juicingallowspeopletointake muchlarger quantitiesof cannabinoidsthanwithtraditional cannabisoil.
  • 128. 128 In additiontoKristen’samazingrecovery, Leaf detailsthe storyof Amber,a2-yearold diagnosedwith braintumors. Withtreatment,Amberwasgivenonlya10% chance to live. However,evenafter surgery,radiation,andchemotherapy, hertumorscontinuedtogrow andmultiply. The doctorsthen sentthe baby home tocomfortablydie. The parentsbegantoaccept that the illnesshadtakenher. Thankfully,theylearnedof juicingcannabis,andbeganjuicingthe fanleavesof cannabisplants. Amber was givenashot-glassof the juice everyday. Withinamonth,the familyreportedthataCAT scan showedthe braintumorsreducedinnumberandsize. The babyis nolongeron hospice,although whetherthere was complete resolutionof the cancerisnotaddressedinthe documentary. Leaf isalsonotable fordiscussingcellularmechanismsbywhichcannabinoidsregulatethe body. As discussedinthe OverviewofSupportingScience section,the endocannabinoidsystemregulates manyaspectsof the bodyand helpsmaintainhomeostasis. Dr.Courtneyexplainsthatone of these mechanismsisprovidingpost-synapticfeedback. Thatis,whena cell sendsamessage toanothercell, the receivingcell cansendamessage backto the transmittingcell generallyindicatingsuccessorfailure. The concept issimilartoacknowledgementandnegative-acknowledgement(ACKandNAK) messages usedincomputernetworking,whereinreceivingterminalsletsendingterminalsknow whetherthe previousmessage wasreceivedcorrectly. Inbiochemistry,itmaybe thatendocannabinoidsfill thisrole, and if cellularcommunicationisimpaired,cannabinoids(eitherendoorphyto) cancorrect it. Thiswould explainwhycannabinoidsare effective againstsomanyconditions, mostof whichlikelyarise from miscommunicationbetweencells orsome kindof cellularimbalance. While muchof thisistheory, the concepts perfectlyexplain the experiential resultsobserved. Furthermore,aDecember2012 study titledThe evolutionand comparative neurobiology of endocannabinoidsignaling describeshow an endocannabinoidcalled2-AGmediatesretrogradesignalingatsynapsesinthe nervoussystemof aleech species,andpostulates“anancientrole forcannabinoidreceptorsasaxonal regulatorsof neuronal signaling”(http://www.ncbi.nlm.nih.gov/pubmed/23108540). Dr. Courtney’s observationswereexploredfurtherwiththe publicationof aHuffington Post article in earlyDecember2012 (http://www.huffingtonpost.com/2012/12/01/cannabis-for-infants- brai_n_2224898.html). He describesan8-montholdpatientwhohada large,centrallylocated, inoperable braintumor. The fatherattemptedtoprocure cannabistreatmentforthe child,andbydoing
  • 129. 129 so,was successfullyabletoavoidchemotherapyandradiation. The parentsbeganputtinga3.8% CBD oil on the baby’spacifiertwice aday,and withintwomonthsadramatic reductionwasobserved. The pediatriconcologistthenallowedthe parentstocontinue withouttraditional therapysince evidence was showingsuccess. By8 months,the tumoris essentiallygone andnormal brainarchitecture has resumed. An extensiveHuffington Post LivesegmentfeaturesinterviewswithDr.WilliamCourtney,Brave Mykayla’sparents,andJasonDavid,the fatherof a childnamedJaydenwhohasDravetsyndrome (http://live.huffingtonpost.com/r/segment/parents-choose/50b663372b8c2a5d91000184). Jayden’s storyis examinedalongside CharlotteFigi inasegmentbelow. Atthe endof thisvideo,Dr.Courtney recountsanotherpatientwho wentthroughtraditional therapyof surgery,chemotherapyandradiation, yetwas still senthome onhospice afterthe failuresof those treatments. The patientbeganjuicingjust the leavesof cannabisplants,andnowtwoyears lateris alive withnotrace of the tumor. While not stated,it’spossible the referencedpatientisAmber,the younggirl from Leaf. Dr. Raphael Mechoulam, whodiscoveredTHCin1964, recentlycalledforclinical trials of cannabisextractsforcancer (http://www.prweb.com/releases/Research-Cancer/Cannabis- Extracts/prweb11564012.htm). He wasjoinedby UnitedPatientsGroupandDr. Sunil Aggarwal,a 2014– 15 Clinical FellowinHospice andPalliative Medicine atthe National Institutesof HealthClinicalCenter. Dr. Mechoulam’sfull statementisasfollows: “There are manyanecdotal reportsonthe use of cannabisand variouscannabisextractsforthe successful treatmentof variouscancers.Howeveruntil well plannedclinical trialshave beenconducted and positive resultshave beenpublishedIdonotbelieve thatcannabisinanyformwill be widely acceptedas a cancer treatment.Hence Istronglysuggestthatsuchtrialsshouldbe plannedand undertakenassoonas possible.”
  • 130. 130 Dr. Manuel Guzmán,whose researchprovedcannabinoidskillbrain,skin,andpancreaticcancer cells,isalsoadvocatingforclinical trials. Onthe InternationalAssociationforCannabinoidMedicines website, Guzmánstated,“There are still manyunansweredquestionsaroundthe potential forusing cannabinoidsasanticancerdrugs,andit isnecessaryanddesirable thatexhaustiveclinical studiesare conductedtodetermine howcannabinoidscanbe used,otherthanfortheirpalliativeeffects,totreat cancer patients”(http://www.cannabis-med.org/index.php?tpl=faq&red=faqlist&id=274&lng=en). Furthercallingforresearchintocannabisandcancer, and decriminalizationspecificallyforthat purpose,isthe GreenParty in Wales(http://www.southwales-eveningpost.co.uk/Gren-Party-Wales- calls-decriminalisation/story-20564358-detail/story.html). PartyleaderPippaBartolotti stated, “I have recentlyreadthroughsome 37 peerreviewed papersall of whichcome toone startling conclusion — thatthe non-psychoactive (knownasCBD) componentinthe readilygrowncannabisplant has the abilitytodestroycancercells. The remarkable medicinalpropertiesof cannabisshouldnotbe overlooked justbecauseitis easyto grow inyourown backyard,and the patentisn’tunderthe control of multinationalcorporations. It reallyisunsupportablethatthose whohave alreadydiscoveredthe benefitsof CBDshouldbe treatedas criminalsinthiscountry.” One of the mostwell known andpopulartestimonialsregardingcannabisextractmedicine is that of Charlotte Figi. Herstory was toldon Dr. SanjayGupta’s documentary Weed,whichpremiered August11th , 2013.
  • 131. 131 Shortlybefore the documentaryaired, Charlotte’sstorywaspublishedonCNN (http://www.cnn.com/2013/08/07/health/charlotte-child-medical-marijuana/index.html). Charlotte’s parentslearnedaboutthe potential forcannabisintreating DravetsyndromeapparentlyfromJayden David’sstory (the CNN article simplystatesthatMatt Figi foundavideoonline of aCaliforniaboywith Dravetsuccessfully beingtreatedwithhigh-CBDoil,and thatboyis mostlikelyJayden). At the time whenCharlotte’sparentsbegantoconsidercannabis, Charlotte’sconditionhad deteriorateddramatically. She couldnotwalk,talk,oreat,and was having300 grand mal seizuresa week. Suchseizuresaffectthe entire brain. Nocombinationof powerfulpharmaceuticalsorrigid dietarychanges,suchas puttingCharlotte onthe ketogenicdiet,hadanyeffect. WhenCharlotte was5, the Figislearnedthere wasnothingmore the hospitalcoulddo. That’swhentheypursuedcannabis extracttreatment. Paige Figi,Charlotte’smother,purchased2ouncesof high-CBDcannabisfor$800, and a friendproducedoil fromthe material. Fromthe veryfirstdose,Charlotte’sseizuresstopped. As the CNN article states, "‘Whenshe didn'thave those three,fourseizuresthatfirsthour,thatwas the firstsign,’ Paige recalled. ‘AndIthoughtwell,‘Let'sgoanotherhour,thishasgot to be a fluke.’' The seizuresstoppedforanotherhour.Andforthe followingsevendays.”
  • 132. 132 Aftertheirinitial positive trial withcannabisoil,Paige learnedof the Stanleybrothers,ateamof individualsspecializingingrowinghigh-CBDcannabis. The Stanleybrothersconsistof Josh,Jesse,Joel, Jon,Jordan,Jared,and J Austin. Theystartedthe Realmof CaringFoundation,anon-profitorganization, to provide childrenandadultswithcannabisforsevere conditions. The Stanleysbeganproviding Charlotte withoil,andevennamedastrainafterher – Charlotte’sWeb. At the time of the CNN article,Charlotte was6. This isjustone year afterthe hospital toldthe Figis nothingmore couldbe done. Withthe use of high-CBDoil,Charlotte’sseizuresdroppedsubstantially.
  • 133. 133 Where she usedto have 300 grand malsa week, she now hasonly a few veryminorseizures each month. “Today,Charlotte,6, isthriving.Herseizuresonlyhappentwotothree timespermonth,almost solelyinhersleep.Notonlyisshe walking,she canride herbicycle.She feedsherself andistalking more and more each day. ‘I literallysee Charlotte'sbrainmakingconnectionsthathaven'tbeenmade inyears,’Matt[Figi] said.‘My thoughtnowis,whywere we the onesthat had to go outand findthiscure?This natural cure? How come a doctor didn'tknowaboutthis?How come theydidn'tmake me aware of this?’” Charlotte’scase wasdiscussedinthe May 2014 issue of Epilepsia,whichconfirmedCharlotte’s dramaticreductioninseizureshaspersistedfor20 monthsand she has beensuccessfullyweanedfrom otherantiepilepticdrugs(http://www.ncbi.nlm.nih.gov/pubmed/24854149). Anotherpatientwiththe same conditionasCharlotte,whose storyapparentlypromptedthe Figistopursue cannabistherapy,isJaydenDavid. He and hisfatherJasonhave appearedonnumerous mediaoutletstoshare Jayden’sstory. Inthe Dr. Courtney Huffington PostLivevideomentionedabove, JasonDavidjoinedintoelaborate uponJayden’sexperience. Jaydeniscurrently6 yearsold. He had hisfirstseizure at4 monthsold. Christmasmorningwashisfirst seizure. Forfour-and-a-halfyears,he hadat leastone seizure everysingle day. Twelvedifferent medicationswere attemptedandnone worked, noteventhe experimental ones. Jasonbegangiving Jaydenhigh-CBDoil inabase of coconutoil. Shortlyafter,hisconditionimproveddramatically –where Jaydenwasonce oftenstuckin a wheelchair,he isnow runningaround,playing,and“beingachild again.” JasongetshismedicationfromHarborside HealthCenter,arguablythe mostadvanced medicinal cannabisfacilityinthe country. Ata newsconference atOaklandCityHall,Jasonmade aplea alongside Harborside’sowner,StephenDeAngelo,toallow the continueddistributionof cannabis medicine. Itwas alsoat thisconference JasonrevealedJaydenhadendured45ambulance tripsinhis lifetime, andhasn’tbeeninanambulance since startingCBDoil medication. (http://www.sfgate.com/crime/article/Oakland-s-Harborside-pot-club-fights-feds-3702632.php).
  • 134. 134
  • 135. 135 Gettingback to Realmof Caring,itis importanttonote that Charlotte Figi isnottheironlysuccess story. Anotherof theirpatients,LandonRiddle,wasusinghigh-CBDoil forleukemia. Dr.SanjayGupta also examinedthiscase,butforsome reasonitwascut outof the Weed documentaryandonlymade available online (http://www.youtube.com/watch?v=Pk9NQxWElXg). Dr. Gupta and SierraRiddle,Landon’smother,describedthe severityof Landon’scondition. At2, he was diagnosedwithleukemia. Doctorsimmediatelystartedintense chemotherapy,butsaidevenwith that, he onlyhadaround an 8% chance of living24-48 hours. AsGupta stated,“The chemomade him violentlyill. He wasin intense pain,he sufferednerve damage inhislegs,andhe went25 days without eating.” Aroundthe clock,he was on a wide varietyof pharmaceuticalsandpainkillers. Sierrathen learnedaboutmedicinalcannabis,andfoundRealmof Caring. Assoonas theybeganthe oil,Landon’s bloodplateletcountimprovedsubstantially, returningtoa healthylevel. Atthe endof the video,Dr. Gupta statesLandonhas beenoff chemotherapyforthree weeks,andthatSierrastatedLandon’scancer was inremission.
  • 136. 136 A currentlyongoingproblemwithregardstoLandon’scase isthat Sierrahas beenreportedtoHuman Servicesbya doctorfor nowrefusing furtherchemotherapytoLandon (http://www.huffingtonpost.com/2013/09/30/marijuana-over-chemo_n_4017985.html). The law technicallyrequiresthatevenafterremission,childrencontinue undergoing chemotherapytoensure the cancer is completelygone anddoesn’treturn. This chemotherapeuticpractice isnotentirelywrong, nor isthe practice of reportingparentstoHumans Servicesif theyare relyingonatrulyineffective treatment,like the exclusiveuse of prayerwithoutany otherformof treatment. However,whena treatmentlike cannabisoil has sostronglyindicated tobe effectiveingeneral,proventobe effectivein the patient’sindividual case, andthe use of chemotherapy hasresultedin unbearableside effects,itis nothingshortof evil to require furtherchemotherapytreatment. Atthe veryleast,the resultsare more than enoughtosubstantiate continueduse of non-toxic,side-effect-freecannabisextracts,with chemotherapyatthe readyinthe case of failure. Itisalsoof note thatBrave Mykaylaisrequiredto continue withchemotherapyaswell (https://www.facebook.com/BraveMyKayla/posts/212591228870849). Realmof Caring hostsmanyotherstoriesontheirwebsite,dividedintoadultandchildsections. Anothernotable storyisthatof Zaki,a childpatientwithDoose syndrome,anotherrare formof epilepsy like Dravet(http://realmofcaringfoundation.org/what-in-the-world/). However,unlikeCharlotte’s Dravetseizures,Zaki’sepilepticactivityischaracterizedbyhigh-frequency,short-duration,subclinical seizures. AnEEG priorto startingCBD showedsubclinicalseizure activityevery10secondsduringthe day,and 2 to 3 timesmore frequentatnight. Despite trying17 pharmaceuticals,the ketogenicdiet, acupuncture,chiropractic,cranial sacral therapy,energywork,andotherherbal treatments,nothing worked. Because of the extreme frequencyof hisseizures,Zaki hashadliterallyhundredsof thousands of seizuresinhislifetime,andhasexperiencedside effectsfrommedicationslikecrampingbodypains, hair loss,bone loss,abnormal weightgain,aggression,andmore. The nightbefore CBDoil wasfirst started,Zaki had 200 seizures. The nighthe started,he didn’thave any. OnOctober1st , 2012, three monthsintoCBD oil treatment, Zaki hadanotherEEG. The 24-hour testshowed only12 subclinical seizuresthe entire time,anamountwhichnormallywouldoccurinonlytwominutes. Asthe testimonial ends,“He is almostoff of pharmaceuticals.He ishappy,healthy,atthe time of thiswriting9 months seizure free,enjoyingbeing aboy,scaringme on hisbike and skateboard!Itisfantastic.He has an opportunityatlife now.” An October23rd , 2013 article describedthe celebrationof Zaki’sone-yearanniversaryof being seizure free (http://www.csindy.com/coloradosprings/10-year-old-is-seizure-free-after-one-year-of- cannabis-oil/Content?oid=2779991).
  • 137. 137 AnotherstoryfeaturesEmily,whowas diagnosedwithacatastrophicformof epilepsyknownas infantile spasmsatsix monthsof age (http://realmofcaringfoundation.org/emily/). She hadbetween 300-400 seizuresaday at worst(heraverage was 50-100), andevenwith14 attemptedmedicationsand a special diet(likelythe ketogenicdiet),nothinghelped. Emily’smotherlearnedof the successCharlotte and Zaki experiencedwith DravetandDoose syndrome,andwasencouragedtotryCBD treatmentfor Emily. Withlittle time toprepare,Emily’sfamilymovedtoColoradowiththe helpof Realmof Caring. The post on Emilyendsassuch: There are several othersuccessful storiesonRealmOfCaringFoundation.org. Jacob’sexperience isvery similartoothers – he had a severe formof epilepsy,enduredhours-longseizure activity,andresponded extremely poorlytoall pharmaceuticals(http://realmofcaringfoundation.org/jacob/). Jacob’s mother describeshowshe foundRealmof Caringandwhather experience wasbelow:
  • 138. 138 Since the release of Dr.Gupta’sdocumentary,nothingshortof a revolutionhasbegun. Familiesfrom across the countryare comingto Coloradoforaccess to high-CBDcannabisoil, the lastchance fortheir children. Andtheirhopesare payingoff. Charlotte,Jayden,Zaki,Emily,andJacobare not outliers. Mostcasesare showingdramatic,miraculousimprovements. Dr.Margaret Gedde,a ColoradoSprings physician,istrackingseveral patientsof Realmof Caring. She recentlyauthoredapapertitled“Whole CannabisExtractof HighConcentrationCannabidiol MayCalmSeizuresinHighly RefractoryPediatric Epilepsies,”whichreportedthe resultsof high-CBDtreatmentinseveral patients.
  • 139. 139 Otherdoctors are takingnote of these amazingresultsanddemandingimmediate action. Dr.Francis Filloux,the top pediatricneurologistatthe Universityof Utah,alongwithtwocolleagueshave come out insupportof high-CBDmedicine(http://www.sltrib.com/sltrib/news/57118270-78/utah-marijuana- hemp-colorado.html.csp). “‘I wouldlike toexpressmystrongbelief that[cannabidiol]-basedoils(referredtohere inUtah as Alepsia) shouldbe available assoonaspossible toUtahchildrenwithsevere epilepsy.The substance isnot psychoactíve or hallucinogenic,itcontainslessTHCthando othermaterialsthatcan be legally purchasedinUtah, and ithas absolutelynoabuse potential,’ declaredFrancisFilloux,chief of the U.’s Divisionof PediatricNeurology,inalettersharedTuesdaywithUtah’sControlledSubstancesAdvisory Committee.” Growingsupportisalsocomingfrom politicians. Gage Froerer, astate representativefrom Utah, isfightingtoimporthigh-CBDcannabisoil intohisstate tohelpchildren (http://www.sltrib.com/sltrib/news/56968773-78/epilepsy-utah-isaac-sintz.html.csp). He recentlysaid momentumisbuildingtolegalizethisformof cannabis, althoughthere are some concernswithinthe Utah legislature aboutconflictswithfederal law andpotential long-termhealthconsequencesof cannabisoil use (http://www.standard.net/stories/2013/11/20/froerer-predicts-cannabis-bill-will-pass). Nonetheless,the supportinUtahhas beenacceleratingquicklyanditislikelythatsome kindof reform will be implemented.
  • 140. 140 JenniferandJacobWelton,the parentsof ZanderWelton,have filedalawsuitagainstthe state of Arizonatoensure uninterrupted,continued accesstohigh-CBDcannabisoil (http://abcnews.go.com/Health/parents-file-suit-son-medicinal-marijuana-extract/story?id=20740614). Zanderhas cortical dysplasia,anduntil he wasgivenhigh-CBDoil,noprevioustreatmentshad workedto control hisseizures. Asthe ABCNewsarticle reports, “Priorto the treatment,the 5-year-oldhadreceivedmanyotherkindsof medicationandhad undergone twobrainsurgeriesinanefforttoalleviatethe severityof hisseizures.Doctorshadremoved part of hishippocampusandhislefttemporal lobe,buthisseizurespersisted.Accordingtothe Weltons, Zander'sdoctor saidtheirfinal optiontoalleviate hisseizureswastoremove the lefthemisphere of his brain.The procedure couldhave lefthimparalyzedorina vegetative state,sotheydecidedtotrythe cannabisoil optionfirst. Zanderwas puton cannabidiol oil,orCBD,inSeptemberafterhe qualifiedforamedical marijuanacard. There are approximately40minorsinArizonawhoqualifyforamedical marijuanacard. Accordingto court documents,the WeltonsnoticedanimprovementinZander'ssymptoms afterbeingtreatedwithmedical marijuana.WeltonconfirmedthataftertreatmentZandernolonger had 8- to 10-minute seizuresdailythatwouldcause himtostopbreathingandturn blue.Instead,inthe sevenweekssinceZanderhadbeentakingmedicinal marijuana,Weltonsaidhe hadonlytwoseizures and eachonlylasteda fewminutesandhe didn'tstopbreathing. In addition,Zanderhasbeenable tocommunicate more andhasstartedto shake hishead signifyingwhenhe doesn'tlike something.” A November2013 episode of TheDoctors,a syndicatedtalkshow,featuredadiscussionbetweenDr. TravisStork, Paige Figi,andDr.Orrin Devinsky. Charlotte’sstorywasrecounted,andDr.Stork passionatelyimploredthe audience tounderstand how amazingherturnaroundwas.
  • 141. 141 The use of cannabisextractsforepilepsyisnotlimitedtothe UnitedStates,nortohigh-cannabidiol oils. In Australia,ayounggirl namedTara O’Connell hasbeenusingTHC-acidtincture totreatDravet syndrome (http://www.heraldsun.com.au/news/victoria/desperate-parents-turn-to-medical-marijuana- in-lastditch-effort-to-improve-their-childrens-lives/story-fni0fit3-1226799787147). THC-A isthe unheated,non-decarboxylatedformof THC,and is non-psychoactive like CBD. Before treatment,Tara was havingupto 60 seizuresaday. Hermotherstated,“She was dying,she couldbarelywalkortalk, was unable totoiletherself andsleptasimilarcycle toa newborn. Overayear,Tara’s condition improveddramatically –herseizuresstopped,she nolongerneedsawheelchair,andarecent neuropsychological assessmentsaidheroverallcognitive performanceswere “significantlyimprovedon those documented12monthsago.” A Melbourne ChildNeurologydoctor,LindsayJ.Smith,saidTara’s improvementwas“nothingshortof miraculous” (http://www.bendigoadvertiser.com.au/story/2041114/mother-holds-hope-for-trial-as-support-grows).
  • 142. 142 Tara’s motherisalsousingthe tincture for herson Sean,who wasdiagnosedwith alesssevere epileptic condition. He isnowseizure free and exhibitingotherimprovements. The producerof the extract Tara and Seanuse isTony Bower,whosuppliesmore than400 people aroundAustralia (http://www.bendigoadvertiser.com.au/story/2055844/marijuana-grower-says-medical-trial-is- needed/). Tonyhasenduredlegal troublesforillegallygrowingcannabis,andin2013 he spentsix weeks inprisonfor the charge. Like manydoctorsand researchers,Tonywantsformal medical trials,andeven has a page on hiswebsite dedicatedtosuchresearch (http://www.mullawaysmedicalcannabis.com.au/clinical.html).
  • 143. 143 An April 26th , 2014 article inThe Toronto Sundescribedthe case of Mia Wilkinson,whosuffersfroma rare epilepticdisordercalledOhtaharasyndrome(http://www.torontosun.com/2014/04/26/medical- marijuana-gives-epileptic-child-new-lease-on-life). The conditionistypicallyfatal withintwoyears of beingborn;infact, Mia experiencedherfirstseizure just29minutesafterbirth. Mia eventuallybegan suffering100 seizuresaday. Her parentswere eventuallytoldbyMia’sneurologistthatnothingmore couldbe done,and were almostreadytogive upafterseeingtheirdaughterinanothermedically- inducedcoma. As a lastresort,theyaskedtheirdoctorif theycouldtrycannabisoil. Giventhat all pharmaceuticalshadfailed,he agreed. Withinone dayof tryingcannabisoil,there were drastic changes,includingacessationof Mia’sseizures. AnEEG showedthe oil had“calmedherraging brain.” Doctors saidthe EEG was comparable tosomeone withabenignformof epilepsy,afterjustone day. Mia is nowdownfrom100 seizuresadayto seveninthe past eightmonths,andhasalsogone from beingcompletelyspeechlesstousingmultiple words. An April 12th , 2014 WashingtonPost.comarticle examinedseveral familiesfromNorthernVirginia resortingtocannabisextractsto treattheirchildren (http://www.washingtonpost.com/local/northern- va-families-move-to-colorado-to-get-medical-marijuana-for-children-with- epilepsy/2014/04/12/859b65a6-bf60-11e3-b195-dd0c1174052c_story.html). JenniferCollins,ateenage epilepsypatient,experiencedupto300 seizuresaday. Afterbeginningcannabisoil (likely high-CBD), Jennifer’sseizureshave “all butstopped.” Moreover,Jennifersaysshe feelsalotbetter – she can focus more,doesbetteronschool tests,hasbettermemory. The cannabisextract’seffectivenessisclearly extendingbeyondseizurecontrol, whichaloneispotentiallylife-saving. Anotherpatient’smother,Dara Lightle,sawherdaughterMadeline experience adrasticreductioninseizures. Moreover,“unbelievable anger,kicking,andscreaming”were replacedwithreading,andall otherdrugsbesidescannabisoil were discarded. Before-and-afterEEGsshoweddrasticdifferences.
  • 144. 144 In lightof these successes,primarilythoseinthe UnitedStates,the EpilepsyFoundationhascalledfor bothincreasedmedicinalcannabisaccessandresearch (https://www.epilepsy.com/newsfeeds/press_release/1002788). “The EpilepsyFoundationsupportsthe rightsof patientsandfamilieslivingwithseizuresandepilepsyto access physiciandirectedcare,includingmedical marijuana.Nothingshouldstandinthe wayof patients gainingaccessto potentiallylife-savingtreatment.If apatientandtheirhealthcare professionalsfeel that the potential benefitsof medical marijuanaforuncontrolledepilepsyoutweighthe risks,then familiesneedtohave thatlegal optionnow -- notinfive yearsor tenyears.For people livingwithsevere uncontrolledepilepsy,time isnotontheirside.Thisisaveryimportant,difficult,andpersonal decision that shouldbe made bya patientandfamilyworkingwiththeirhealthcare team.” The pressrelease alsostressedthe needforunbiasedclinical trials,statingfurtherresearchwill establishmore aboutthe safetyandefficacyof variousextracts. Anothergroupknownas the VitaminCannabisteam inColoradohasdone exceptional work. Kyle Marsh,the leader,detailedtheirwork inadocumentarycalledVitaminCannabis,releasedin September2010 (http://www.youtube.com/watch?v=rMvMEwpCaOA). Kylelearnedaboutthe potential forcannabisandcancerfrom RickSimpson,andhisteamof growersbeganproducingcannabis oil to see if Rick’sclaimswere reallytrue. Kyle happenedtohave a60-year olduncle at the time with some formof cancer. Doctorshad not identifiedwhattype of cancerit wasyet,and Kyle’suncle was essentiallytoldtowaituntil itgotworse,soit wouldbe more easilyidentifiable andthentreatedwith radiation. Meanwhile,Kyleandhisteamhadjust begunproducingcannabisoil,whichtheyrefertoas Phoenix Tearsinhonorof Rick. Kyle toldhisuncle aboutcannabisoil,andhe watched Run Fromthe Cure. He thendecidedtouse Phoenix Tearsinsteadof traditional treatment.
  • 145. 145 A notable aspectof Kyle’soperationswasthe remarkableeffortputintomeasuringoutdosesand establishingpropertreatmentregiments. The rigidclassificationsallowedKyle’steamtobettertrack results,andtheybegantestingthe oil on people. One glaucomapatientsubstitutedtheir$600/montheye dropsfor oil capsulesandreportsno needforprescriptionsafterone monthof treatment. AsKyle’suncle continuestreatment,hiscondition
  • 146. 146 progressivelyimproves,until hisonce debilitatingpainisgone. He decidestomove ontothe SuperC pills. A monthafterdoingso,a cancerspecialistdeterminedhiscancerisgone. One of the mostscience-orientedgroupsinvolvedinthe cannabisextractmovementisBudBuddies, foundedin2002 by Jeff Ditchfield. Jeff also ranThe BeggarsBelief,aDutch-style cannabiscafé. Due to the UnitedKingdom’sharshcannabislaws,Jeff experiencedsix police raidsonThe BeggarsBelief and numerousarrests. Thisneverstoppedhimfrom helpingothers,butitdidforce himtorelocate toSpain. Jeff’swell-roundedexperience isevidencedbyhislectures atThe Royal College of General Practitioners and JohnMores University,aswell ashisappearances onseveral televisionstationsandradioprograms, includingParliamentTV andBBC1. WhenJeff movedhisorganizationfromthe UKto Spain,he alsoswitchedhisfocustohelpingcancer patients. Histreatmentregimentsforfightingcancer are largely basedoncontinuouslygrowing experiential evidence andthe workof Dr. Manuel Guzmán.
  • 147. 147 To publicize the veryreal strugglespatientsgothrough to simplyaccessaneffectivemedicine,Jeff is currentlyproducingProjectStorm. Thisdocumentaryfollowssix terminalcancerpatients,includingtwo children,astheyuse cannabisextractstoheal. Jeff describesProjectStormasfollows: “ProjectStormis a documentaryfollowingthe lives of 6 UK terminal cancer patients who have all been told there is nothing more that their doctors can do for them, however the brave individuals didn’t accept this devastating news and they started to research alternative therapies and their journey led them to Bud Buddies and ‘Project Storm’. Our protocolsfor the project have been drawn up based on the research of Professor Manuel Guzman and his team at Madrid University who are pioneers in the research into cannabinoids and cancer, I’m very much looking forward to meeting them again at Madrid University next month. Filmslike ‘Runfromthe Cure’have inspiredthousandsof people butwe wantedtomake adocumentary ‘inreal time’,all the participantsinthe filmstartedonthe oil aroundChristmaslastyear,thisisn’ta film to ‘prove’thatcannabinoids‘kill’ cancer,itisthe storyof the 6 people inthe filmandtheirjourney.” The above is takenfroman interview Jeff hadwithMel Thomas,whichhe providedtothe author. In thisinterview,Jeffalsoansweredthe questionof whetherthe anti-cancereffectivenessof cannabis extractsismerelyanecdotal,andofferedsome insightintowhatstrainsworkbestforwhichcancers. “For me the evidenceof cannabisoil sending cancers into remission is far from anecdotal and we have manycases of its success,howeverIdon'tconsiderthat any one individual haseverbeen'cured'.I much prefer the term 'treatment' to 'cure', if the oil truly was a cure then a person’s cancer would go into remission and not return but it is obvious that there is a daily need for a 'maintenance dose' to keep cancer in remission. Your choice of strain depends very much on the cancer you are treating. Many conditions such as lung cancer respondwell tohighTHC oils, however, if you are treating Gliomas or any form of brain tumour then we have found that a 1:1 THC/CBD strain is the most effective. The Universityof Madridresearchindicatesthatthe mosteffective combinationof cannabinoidsto treat Gliomasisa 50/50 THC/CBD ratio,thiscombinationwasfoundtobe more effectiveagainstGlioma cellsthaneitherTHCor CBD on theirown.” The full trailerforProjectStormcan be foundhere: https://www.youtube.com/watch?v=ah3Y4_ahm5I. Donationstosupportthe film’scompletionare neededandcanbe made throughProjectStorm’s website athttp://projectstormthefilm.com. Beloware several imagesfromthe film, including renownedSpanishresearcherGuillermoVelasco,one of Manuel Guzmán’spartners.
  • 148. 148 A documentary called“Canada’sNewOil Men”detailsthe workof those remaininginCanada,whohad learnedfromRickSimpsonthe full benefitsof cannabisoil (http://www.youtube.com/watch?v=mInW- MF8RAA). AfterRick left,severalpeople remainedtocarry on hiswork. A filmmakernamedChris Harrigan produceda documentarytotell the storyof one such person,Daren McCormick.
  • 149. 149 In the video,Darendescribesmanyof hisexperiencestreatingotherswithcancer. Manypeople would come to himfor help,andall Darenaskedin returnforprovidingmedicine wastoknow the results. He statedthere was“nevera failure”,althoughthere wasnoindication whetherthisstatement meantall patientswere curedorjustimprovedsomehow. However,aspecificreference tothe treatmentof skin cancer ismade. Daren saysthat in Halifax, he providedlessthan1mLof oil toa man withskincancer. The man appliedittothe skincancerwith a bandage,and infourdays,the cancer wasgone. At the end,filmmakerChrisHarriganstatesthatDaren has recentlybeensentencedtothree yearsin prisonforhistechnicallyillicitactivities. ChrisfeelsindebtedtoDaren fortreatinga friend,and wantsto help Darenand all the others whohave beenunjustlypersecutedfortryingtosave others. One of the mostwell knowncannabisoil producerswasRonnie Smith,whoworkedwithavarietyof individualsthroughouthisoil makingcareer. Ronnie oftenwentby the aliasRolandA.Dubyandwas arguablythe most boldanddaringpersonainthe movement. Forat leastsix years,he publically advertisedthroughall formsof social mediathathe wouldsendafull treatment’sworthof oil toanyone inthe UnitedStatesfor$2,000. He includedhisphone number,whichsomehow he neverneededto
  • 150. 150 change,ineverypost. Ronnie frequentlysentfree cannabisoil topatientsinneed,includingseveral the author personallyreferredwhohadnootheroptions. Before becoming acannabisoil distributor, Ronnie wasJack Herer’spersonal assistantforfouryears,andhelpededitthe 2007 editionof The EmperorWears no Clothes. In an October2012 Facebookpost,Ronnie recountshow he gotinvolved withcannabisoil (https://www.facebook.com/notes/roland-a-duby/what-the-hell-did-i- do/501436303207704). “My name isRonnie Smith.IwasJack Herer'spersonal assistantfor4 years andI editedthe 2007 edition of hisbook.While livingwithJack,IfoundoutI had cancer,and I had lumpsinbetweeneachknuckle and a lumphangingoutmy rear. ... I was growingpotat the time withJack andhis wife andmyjobwas to make the bubble hashfromthe trimmings.While makingthe hashIwouldeata spoonfull onoccassion,andIdidthat four or five times a day for a couple months.Inoticedaftera month that the lumpsbetweenmyknucklesgotsofterand after2 months,theywere gone.Jacksaidthathe wrote inhisbookabout a college studywhere they killedcancerinratswithTHC inthe 70's. His wife googledthe article andinthe search,she foundRick Simpsonandthe story aboutthe oil.Thiswas 2006, and we calledRick,andRick turnedoutto be a big fan of Jacks,so Jack had himon the Jack HererTV show everyweek.Ricksaidhe neededsomeone in Americato make oil andI volunteered.He sentme referalsfor3yearsbefore he got stuckineurope.by 2010 I had curedover200 people.IdecidedtorunforSheriff andmake the cure available forfree to anyone inmy county.” Ronnie appearedinanApril 2013 interview,where he discussedhisexperiencesand observationsfromyearsinthe movement (https://www.youtube.com/watch?v=QFKo8yz8yjA). Bythis point,he claimstohave cured over300 people of variouscancerswitha75-80% successrate. This particularvideoconveysRonnie’spersonalityandintelligence veryeffectively. Ronnie passedawayinearlyApril 2014. Hispassingwasa greatlossto the cannabiscommunityandthe worldat large. Ronnie wasa friendof the authorand it istragic he will notgetto see the ultimate fruits of hislabor. However,hisworkwill foreverlive on,andhisuniquenesswill notbe forgotten.
  • 151. 151 Ronnie wasalsoa skilled(inthe author’sopinion) stand-upcomedian. A 2005 performance inwhich he opensforDoug Stanhope can be viewedhere: https://www.youtube.com/watch?v=jtGWui7i8DI.
  • 152. 152 6. Concluding Discussion The amount of evidence supportingthe effectivenessof cannabis extractmedicineisstaggering. Ashas beenshown,peoplefromall walksof life have used manytypesof cannabisextractstoeliminate varioustypesof cancer andcompletelycontrol oreliminate amultitude of otherdiseases. Firstof note isthe versatilityof cannabis extracts. High-THCoil,high-CBDoil,juicedcannabis, industrial hempoils,and whole plantbalancedextractionshave all demonstrated remarkable effectiveness. These medicineshave beenadministeredintopical,oral,vaporization,andeven suppositoryforms. The general trendhasbeenthis - extractsderived fromhigh-qualitystarting materials,withaproperextractionprocess,andadministeredproperly inthe necessaryquantities,can achieve miraculoushealingresults. One of the true original goalsof the cannabisextract movementhasbeentosecure clinical testingof cannabisoil toprove itseffectiveness definitively. Asmentioned,RickDwyertriedtotake this route many yearsago,but unfortunatelynothingcame of those efforts. It isunfortunate thatno true clinical trialshave beencarriedoutsince the releaseof Run FromtheCure and the initial pleasforsuchtrials. Whyhave theynotbeendone? While the answerscanonlybe speculatedupon,there are some possibleexplanations. First,cannabisis,forthe mostpart, a globally illicitdrug. Itsresearchisheavilyrestricted inthe UnitedStatesandmoderatelyrestrictedinmanyother parts of the world. Of course,there are many countrieswhere cannabislawsare laxer,sothe illegality of cannabiscannottotallyexplainthe lackof trials. There isalsoa widespreadlack of knowledge regardingthe extensive therapeuticpotential of cannabisextracts,andmostresearchhasjustfocused on humansmoking,animal,orculture studies. Writingaresearchpaperon the abilityof cannabinoids to inhibitthe growthof cancercells islikelyacleanerprocessthanarranginga long-termstudyof cannabisoil oncancer patients. Moreover,inmanypartsof the world,high-qualitycannabisis expensive,andthiscouldalsosetupa prohibitive barriertostudies. Anothersignificantbarrierto research,perhapseventhe greatest, isthe general publicsentimentregardingcannabisextract medicine. More insightintothe nature of thissentimentwill be revealedinfurtherdiscussion.
  • 153. 153 Althoughthere have notbeenanytrue clinical trials,manyotherscientificmeritshave been met. A multitude of peer-reviewed,scientificpapersdemonstrate thatendocannabinoids, phytocannabinoids,andsyntheticcannabinoidscanall kill cancercells. Theydothisthrougha wide varietyof mechanisms, suchaspromptingceramide-inducedapoptosisthroughCB1or CB2 receptors, changinggene expression,inhibitingangiogenesis,andexertingreceptor-independentanticancer effects. Studiesshow thatcannabinoidsworkagainstvirtuallyeveryspecificcancer cell type,like prostate,pancreatic,skin,brain,colon,leukemia,lymphoma,andmore. Inaddition,the November 2013 studyin Case Reportsin Oncology provedthe anti-leukemiceffectsof cannabinoidsextendto humansinat leastone case. Furthermore, studiesindicate cannabinoidsexertbeneficial effectsonessentiallyanydisease, like autoimmunedisorders,heartdisease, Crohn’s, diabetes,chronicpain, fibromyalgia,multiple sclerosis, andmore. These widespreadeffectsare theoreticallypossiblebecause of the endocannabinoidsystem. Researchhasshownthe ECSmodulatesmanycritical functionsof the body, likely developedveryearlyinevolutionaryhistory,andis possibly the chief regulatorof systemic homeostasis. Admittedlyunderstated,all diseaseultimatelyresultsinadisruptionof homeostasis. Whenperfecthomeostasisisachieved,disease can’texist –the statesare mutuallyexclusive. Although onlyconjectural,the theoryconvenientlyexplainswhycannabisextractsseem toworkagainstnearly any kindof disease withsuchastoundingsuccessandresolution. The other scientificmeritmetisthatof replication. Manypurportedcancercureshave been shotdownbecause onlythe original creatorsupposedlyobservedresults,oruponfurtherinspection, unacceptable riskswere observed. Butthe cannabisextractmovementisunlike anythingthathascome before. First,the manwhoarguablylaunchedthe movement,RickSimpson,isbyfar notthe only personto have achievedresults. Infact,hisworknow palesincomparisonto the hundredsof others whohave usedor adaptedhistechniques,andthe scientistsand caregivers whohave gone evenfurther withhigh-CBDoil andjuicing. The initial claimsof cannabis eliminatingcancerhave beenreplicatedtime and time again. Fromthe veryfirstpeople whotookRickupon hischallenge toputiton a skincancer and see whathappens,toDr. WilliamCourtneyshrinkingan8-monthold’sbraintumorwithhigh-CBD oil,itjustkeepshappening. There isno denying thatthere issomethingworthinvestigatinghere. Itisabsurdlyunlikelythat all of these case reportsandrelevantempirical findingsare all coincidences,andthatthere isno relationshipbetweencannabinoidsandcancerand the many otherdiseasesdiscussedinthisreport. Many cases existwhere peoplewhousedcannabisoil withor withouttraditional chemotherapy, radiation,and/orsurgeryreachedsuccess. Infact,the successesalongside traditional treatmenthave sometimesbeenevenmore remarkablethanthose withoutit. Manypeople,evenchildrenlike Brave Mykaylaand Landon Riddle,have reducedchemotherapyside effectstonearzero,while also eliminatingthe cancersmuchfasterthanexpected. Andothers,like StanRutnerandJoanne Crowther, enduredchemotherapyandradiation, onlytobe toldtheywere still goingtodie. Yetwithcannabisoil treatment,theywere healed. Thenthere are people whobeatcancerwithout the traditional treatment options,like Dr.Courtney’s8-montholdpatientforbraincancer,Corrie Yellandforherinternal anal canal cancer,DennisHill foraggressive prostate cancer, Joe Crowe forHodgkin’slymphoma, David Triplettforskincancer,and the CannabisScience patientforskincancer.
  • 154. 154 Despite the gravityof justthese few cases,theyare still onlyasmall piece of the total patient data that exists. Tomaintainsome semblance of brevity,notall testimonialshave beenincluded. More importantly,there are somanypatientexperiencesthatsimplyhave notbeenrecorded. Noteverybody iswillingtoputtheirpersonal medical informationout there,evenanonymously. Another compoundingfactor,again,isthe fact that cannabisisfederallyillegal. People have takenlegitimate legal risksbysharingtheirexperiences,especiallycaregivers. The courage these individualshave demonstratedin the face of overwhelmingadversity,fromlaw enforcement,society,andthe diseases themselves,isnothingshortof heroic. Conversingwiththe generalpublicaboutthisreality,includinggovernmentandnonprofit officials,isdifficultbecauseof the magnitude andinitial absurdityof the claims. Tellingsomeone that cannabis,a psychoactive plantthatpeople use togethigh,caneffectivelyeliminate many kindsof cancer obviouslycomesoff ludicrous. Asif thattruth didn’tmake thingshardenough, claimingextracts workagainstnearlyany majordisease basicallysealsthe deal onthe statusof the proponent’ssanityin the listener’smind. Due to the sheerlevelof disbelief in suchpossibilities,peopleare generallyunreceptive to higher-level healingclaims. The author,overhisfive yearsof beinginthismovement,hasobserveda surprisinglackof interestinthe claims. Peoplefromall kindsof government,private,andnon-profit organizationsseemtojustbrushthemoff. Essentiallyall the newsreportsthathave spokenabout cannabiscuringcancer do so ina verymatter-of-factfashion,withoutrealizingthe granderimplications of whattheyare talkingabout. Furthermore,manycuredpatientshave hadalarming,dismissive reactionsfrom theirdoctors,ratherthan elated,supportive ones. It’sasif the doctors cannot comprehendthatsomethingotherthantraditional treatmentscouldreallyhave curative effects,and thushave no interest. Thankfully,thereare manydoctors,including those mentionedandnot mentionedinthisreport,whostronglysupportcannabisextractmedicine andare workingtofurtherits advancement. Some people have scoffedatthe notionof cannabisextractstreatingdisease,andsaysuch claimsholdthe medicinal cannabismovementbackbyobscuringthe legitimate benefitsof smokedor vaporizedcannabisforsymptommanagement. These concernsare understandable becauseif cannabis extractsdidn’teffectivelytreatdiseases,thenthe claimswouldindeedbe hurting the movement. Butto dismissthe meritsof cannabisextracts withoutextensivelylookingintothe evidence iswrong,given howmany livesare atstake. No one isgoingto believe cannabishas suchincrediblehealing effects afterfifteenminutes. The evidence anddatamustbe carefullyscrutinized,andif possible,patients shouldbe conversedwithdirectly. Nothingismore effectiveforinstillingpersonal belief inthis movementthantalkingtothe patientswhohave actuallycuredthemselves. Anothertrendthatexistsinthe medicinal cannabisandscientificcommunitiesisalackof urgency. Withoutthe possibilitiesof cannabisextractmedicine,thereisindeednowayto be more urgent– all that couldbe done iswaitfor researchto panout on cannabinoidortraditional pharmaceutical drugs. Butthere isanotherway. Treatmentof terminal cancerpatientswithcannabis extractmedicine couldbegin tomorrowif the rightpeople tookaction. Withintwoorthree months, howmany of themwouldbe cured or have improveddramatically? Itisso easyto prove this. Andwith legalizationinColoradoandWashingtonstates,whatistostopsome collective actiontotreatanentire hospice centerwithdonatedoil andobserve the results? Itwouldn’tevenbe thatexpensive compared
  • 155. 155 to the costs of traditional treatments. Proof couldbe gatheredevenfasterif skincancerpatientsopted to give thisa try before radiationorsurgery,astopical resultsare usuallyachievedmuchfaster than internal treatments. If the resultsare proven,cannabistherapywill instantlyspreadacrossthe entire world. The rapiddisseminationwill be drivenbydesperationandpain,forpeople whoare inpainor are dyinghave notevenone secondtowaitfor relief. Everysingle instantispure agonyandhell. Those whoare not inpaincan easilysay,“We’ll waitacouple yearsformore researchoncannabinoids,then we’ll trysome approachesinhumans,thenintenyearswe couldhave a suitable treatmentforthis group,etc.” But for someone neardeath tohearthat, those are unacceptable notions. Of course, withoutsomethinglike cannabismedicine,all humanitycoulddoiswaitonsuch timescalesforresearch to reveal asolution. Thankfully,we don’tneedto. The solution ishere. It’snot like these cure-levelresultswill magicallystopbeingreplicatedonce appliedinaclinical setting. Infact, the resultsshouldbe evenbetter,since the cannabinoidmedicinesadministeredwould be of the highestquality. Many people have observedtransformationalhealingresultswithonly relativelyimperfectoils. Cannabisoil derivedfromsupercritical carbondioxide orhydroethanolic processescarriedoutincertifiedlabswillcertainlybe betterthanthose formulatedbyindividualsin theirhomesorbackyards. The bottom line –in the face of all thisevidence,whatexcuse isthere to notbeginusing cannabisextractmedicine inhospicesimmediately? The possibilityitwill workisundoubtedlyrealistic, and giventhe costsand benefitsof attemptingsuchtreatment,there isnoexcuse nottomove ahead withthispath. Whenall the objectionsare finallyovercome,and clinical trialsare finallyacceptedand conducted,the truthof cannabismedicinewillbecome clear. Ithas beenobservedtimeandtime again - people getcancer,theyuse cannabisextractmedicineinsome form, andthe cancergoesaway. They getsick fromtraditional treatments,yetare able torecoverandstop usingall the mostpowerful pharmaceuticalsbyreplacingthemwithsimplecannabisextracts. Scientistsconfirmmechanismsby whichthese effectsare conferredin cell,animal,andhumanstudies. Andoverarchingeverythingisthe endocannabinoidsystem,maintaininghomeostasisinthe body. Evenmanytypesof cancer cells,as showninresearch,exhibithigherlevelsof cannabinoidreceptors,sotheyare more susceptibleto apoptosisbyendocannabinoidorphytocannabinoids. There are somany examplesof cannabinoids assertingtheirhealingeffectsatthe mostfundamental andancient evolutionary levels. Insomany cases, cannabis extracts reallyhave worked. Change mustcome as soonas possible. Foreverydayof delay,millionsof people suffer unbearably. Furthermore,people thatare tryingtosave theirownor theirchildrens’livesare being unfairlypersecutedbylawenforcement,andmustbe saved. The case of Landon Riddle wasmentioned, and alsoof importantnote isBentonMackenzie,anIowapatientwithterminal angiosarcomacancer (http://reason.com/blog/2013/09/30/terminal-cancer-patient-in-iowa-entire-f). Bentonwasgrowinga large quantityof cannabisforhistreatment,whichisrequiredforanintegrative approachof cannabisoil ingestionandjuicing. Hispropertywasraided,andBenton spent42 days injail until he wasreleased overconcernsabout howmuchhis medical treatmentmightcostthe prison. People shouldnothave to fightthe lawfor tryingto save theirownlives. Thishasto stop.
  • 156. 156 It shouldbe apparentthatthe currentcourse of medicine isnotcorrect. People regularlygo bankruptpayingformedical treatment,sufferintenselyfromthe treatmentsthemselves,andendure side effectsfromessentiallyeverypharmaceutical. Andatrendthe author has indeedobservedover these manyyearsisthe terrible toll thattraditional pharmaceuticals,chemotherapeuticandnon- chemotherapeuticagentsalike,take onpeople. Theycause tremors,headaches,nausea,pain,mental fogginess,constipation,stomachaches,andmore. A 2003 article inthe journal Drugsstated, “Neurotoxicside effectsof chemotherapyoccurfrequentlyandare oftena reasonto limitthe dose of chemotherapy”(http://www.ncbi.nlm.nih.gov/pubmed/12887262). While thispaper’spurpose isnotto discredittraditionaltherapy,itis probable thatmany traditional treatmentsare farlesseffective than cannabisextractmedicine. There isso much more that mustbe learnedaboutcannabisextracts. Whatstrainsworkbest on whatdiseases,whatisthe bestdosingregiment,whatare the bestextractiontechniques,what individualcannabinoidsare mosteffective onwhatdiseases,etc. The role of nutritionisalsoimmensely important. Recently,the importance of Omega-3sforoptimal functioningof the endocannabinoid systemhasbeenexplored. AnOctober2010 studyin NatureNeurosciencereportedthatnutritional Omega-3deficiencyabolishedendocannabinoid-mediatedneuronal functionsinmice (http://www.nature.com/neuro/journal/v14/n3/full/nn.2736.html). Issuessuchas endocannabinoidsystemdisruptionare one of the possibleexplanationsincases where cannabinoidtreatmentshave failed. Otherexplanationsincludeimpropersource material or usingoil derivedfromabadextractiontechnique. While thisreportalmostexclusivelyexamines successful cases,there of course have beeninstanceswherepeople werenotentirelycured. However, inthe author’sexperience,he cannotrecall anyoutrightfailures. Insome casescancershave returned, like inCashHyde. Otherpeople have notbeenable tototallyeradicate theircancers,withsome persistentremnantsremaining. A fewcouldonlyslow orstopcancer growth. Andfor some,itseems that continuouscannabinoidtreatmentis required. Forexample,the authorhasobservedthatfor people withdiabetes,inordertoavoidusinginsulin,theymustuse cannabisextractsinstead. Could permanenthealingbe achievedwithafull integrative approachof juicingandbalancedcannabisoil treatments? Possibly,butevenif some peopleneedtotake cannabinoidsall theirlives,the onlyside
  • 157. 157 effectsare systemicallybeneficial,andwithhigh-CBDoilsthere isnopsychoactivity. Itmay be that one day everyhumanwill take some formof non-psychoactivecannabis. While cannabisseemstowork effectively againstanincrediblenumberof diseases,there are likelycertainconditionsorinfectionswhichcannabiscannotwork for,andperhapssome people whofor some reasonwon’trespondtothe therapyat all. It is unlikelythatatrue panaceaexists,butcannabisis the closestwe have. Throughresearch,all questionsof effectivenesswill eventuallybe answered. But for now, sickand dyingpatientsmustbe givenaccesstothe highest-qualityextractspresentlyavailable, so that manyof themwill have hope forfuture life. Evenif just1% of the claimsin thisreportwere true – that cannabisoil can mitigate severe formsof epilepsy,cure skincancer,reduce severe chronicpainwithoutopiates,control inflammation, manage diabetes,mitigate Behcet’sdisease, etc. –those truthswoulddemandimmediate action. If cannabisworked betterthanpharmaceuticalsforjustone ailment, itwouldstillwarrantimmediate application. Butashas beenshown,the effectsof cannabis extractmedicineare more profoundly beneficial thananyone everthought. The story of Rick Simpson isfarmore credible inlightof the new worksof scientists,doctors, dispensaries,corporations,andall the regularpeoplethatfollowedinhispath. Everythingmakessense – whyhe defiedjudgesandriskedyearsinprisonto provide free medicine topeople,andthatthe resultshe observedwere real,notjustfoundedinblindfaith. Thankstothe epiccourage of Rick,and the arguably evengreatercourage of the many who soughtout to replicate hisresults andsave their ownlives,the worldhasa real chance at a happy,peaceful future. It isimportantto finishbyunderscoring whatmustbe done next –secure immediatetestingof thismedicine inhospice centers. Whetherthiseffortisleadbydispensaries,individual growers, corporations,orsomeone else,itdoesn’tmatter. Thisneedsto happen now. Livesare at stake every single second. Withthe evidence presentedinthisreport,there trulyisnoexcuse tonottake action. So let’sdoit. “If I’mtellingthe publicanythingthat’sa lie,well whydon’tsomebodycome anddefraudme;whydon’t these medical doctorsstandupand putme inmy place.AndI’ll tell youwhytheycan’tdothat, because I’mtellingthe truthandtheyknowthat.” – RickSimpson “Nothingwill everbe attemptedif all possibleobjectionsmustfirstbe overcome.” –Samuel Johnson “Neverunderestimatethe powerof asmall groupof committedpeopletochange the world.Infact,it is the onlythingthat everhas.”– Margaret Mead
  • 158. 158 KevinBooth,directorof American Drug War 2: CannabisDestiny,usedtoworkwith Bill Hicks,a comedianof great stature. KevinlostBill topancreaticcanceron February26th , 1994, whenBill was only32. Thiseventdoubtlessinspired muchof the granderthemesof American Drug War 2. A verse Hicksauthored,to be releasedafterhisdeath,endedwiththe quote: "I leftinlove,inlaughter,andintruthand wherevertruth,love andlaughterabide,Iamthere inspirit." It isthe author’s ultimate hope thatthe truthof cannabisextractmedicine prevails,solove andlaughter can be the drivingforcesof thisworld,ratherthandespairandpain. With cannabis medicine,the cancer that endedBill’slifewillnolongerbe atorturoushell to millionsof others,andthe dreamsof peace he most certainlyhadwill be realized.

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