1. C U R R I C U L U M V I T A E
DAVID JOHN JACKSON
5 Shaymoor Lane
Pilning
Bristol
South Gloucestershire
BS35 4JR
Telephone: 01454 501412
Mobile: 07752 844932
Email: joydave66@googlemail.com
PROFILE
I am an experienced Senior Research Scientist with over 26 years’ experience in
the UK Transplant Service and the International Blood Group Reference Laboratory,
NHS Blood Transplant in association with Bristol University. I have spent 23 years in
research and 3 years in a diagnostic laboratory working under containment level 3
laboratory conditions.
EXPERIENCE
 HLA serological typing of human cells
 Virology testing of hazardous human blood samples
 Animal and human cell culture
 Animal husbandry
 Production of monoclonal anti-D antibodies by EBV transformation of human
immunised white cells
 Production of human monoclonal antibodies using a SCID mouse model
 Development of peptide therapy to ameliorate human alloantibody responses
 FACS analysis
 Light and fluorescent microscopy
 Confocal microscopy
 Development of assays using radioactive Isotopes
 Platelet immunology
 Diagnostic development of vCJD assays
 Experience of working in a CL3 laboratory
 Production of human recombinant proteins
 Identification of vCJD in samples of human eye and spleen project
 Molecular Biology
 Collaboration with medics, nurses and colleagues to identify potential patients
for a NAIT research project

2.  Talking with patients to explain research projects
 National and International oral presentations of research work
 Research papers (see below)
CAREER SUMMARY
20012- International Blood Group Reference Laboratory
Senior Clinical Scientist
1990-2012 International Blood Group Reference Laboratory
Research Scientist
1989-1990 UK Transplant Service
Scientific Officer
EDUCATION/QUALIFICATIONS
2006-2012 Professional Doctorate in Biomedical Sciences (PhD)
1991-1995 MPhil (Immunology)
1985-1989 BSc(Hons) Applied Biological Sciences
1982-1985 A Levels Chemistry, Biology, Physics
1977-1982 O Levels English, Maths, Biology, Physics, Chemistry,
History, Geography, Technical Drawing, Art
PROFESSIONAL MEMBERSHIP
Health and Care Professions Council(HCPC) –CS02810
British Blood Transfusion Service(BBTS)
PERSONAL
Date of Birth: 3rd February 1966
Married
British
NI no. NH792468D

3. ACTIVITIES/INTERESTS
SPORT: Cycling, running, weight training
OTHER: Photography
VOLUNTARY WORK:
Youth group leader to under privileged children.
Department head of the Sunday School in a large inner city church.
Department head of a team of 40 people responsible for the Hospitality in a large city
church of 400+ people.
Helping to distribute food, drink and clothing to the homeless in Bristol.
Facilitating a team of leaders responsible for the wellbeing and welfare of 40 adults.
Science practical demonstrations and talks to 12-18 year olds.

4. PUBLICATIONS
Human platelet antigen (HPA)-1a peptides do not reliably suppress anti-HPA-
1a responses using a humanized severe combined immunodeficiency (SCID)
mouse model.
Jackson DJ1, Eastlake JL, Kumpel BM.
Clin Exp Immunol 2014 Apr;176(1):23-36.
Ultrastructural localization of glycoprotein IIIa (GPIIIa, beta 3 integrin) on
placental syncytiotrophoblast microvilli: implications for platelet
alloimmunization during pregnancy.
Kumpel BM, Sibley K, Jackson DJ, White G, Soothill PW.
Transfusion. 2008 Oct;48(10):2077-86
Reactivity of T cells from women with antibodies to the human platelet antigen
(HPA)-1a to peptides encompassing the HPA-1 polymorphism.
Jackson DJ1, Murphy MF, Soothill PW, Lucas GF, Elson CJ, Kumpel BM.
Clin Exp Immunol 2005 Oct;142(1):92-102.
Flow cytometric characterisation of cells of differing densities isolated from
human term placentae and enrichment of villous trophoblast cells.
Manoussaka MS1, Jackson DJ, Lock RJ, Sooranna SR, Kumpel BM
Placenta 2005 Apr;26(4):308-18
Reduction of human anti-tetanus toxoid antibody in hu-PBL-SCID mice by
immunodominant peptides of tetanus toxoid.
Jackson DJ1, Elson CJ, Kumpel BM.
Clin Exp Immunol 2004 Aug;137(2):245-52.
Section 1C: Assessment of the functional activity and IgG Fc receptor
utilisation of 64 IgG Rh monoclonal antibodies. Coordinator's report.
Kumpel BM1, Beliard R, Brossard Y, Edelman L, de Haas M, Jackson DJ, Kooyman
P, Ligthart PC, Monchâtre E, Overbeeke MA, Puillandre P, de Romeuf C,Wilkes AM.
Transfus Clin Biol. 2002 Jan;9(1):45-53.
Comparison of flow cytometric assays with isotopic assays of (51)chromium-
labeled cells for estimation of red cell clearance or survival in vivo.

5. Kumpel BM1, Austin EB, Lee D, Jackson DJ, Judson PA, Chapman GE.
Transfusion 2000 Feb;40(2):228-39.
Optimisation of human anti-tetanus toxoid antibody responses and location of
human cells in SCID mice transplanted with human peripheral blood
leucocytes.
Jackson DJ1, Kumpel BM.
Human Antibodies 1997;8(4):181-8.
Characterization and functional activity of human Rh monoclonal antibodies.
Kumpel BM1, Jackson DJ.
Transfus Clin Biol 1996;3(6):453-8.
Human leucocyte antigen (HLA) and malaria morbidity in a Gambian
community.
Bennett S1, Allen SJ, Olerup O, Jackson DJ, Wheeler JG, Rowe PA, Riley
EM, Greenwood BM.
Trans R Soc Trop Med Hyg. 1993 May-Jun;87(3):286-7
Specific anti-A responses of SCID mice populated with human lymphoid cells
from peripheral blood, umbilical cord, bone marrow and spleen after
immunization with group A erythrocytes [corrected].
Kumpel BM1, Poole GD, Jackson DJ.
Immunol Lett 1992 Jul;33(2):163-8.