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Therapeutic uses of tahlab
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Therapeutic uses of tahlab

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Anti-hyperglycaemic activity

Anti-hyperglycaemic activity

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Therapeutic uses of tahlab Therapeutic uses of tahlab Presentation Transcript

  • Presentation by: Dr. Md. Anzar Alam Dept. of Moalajat NIUM, Bangalore-91
  • A. Unani Concept Definition Mutradifat Mizaj Af‟al Mawaqe Istemal Muzir Wa Musleh Badal Meqdare Khorak Ashka‟le Advia Murakkabat
  •  Definition: Tahlab is an Arabic word which means a greeny substance float on surface of the water, commonly known as algae. Synonymous: Greek- Oolisoon Arabic- Tahlab, Hazazul Maa, Ghazalul Maa, Kharuz Zafade, Farsi- Jughraba, Pashme waza Siryani- Tahalba Hindi- Shaiwal, Kaayi Mizaj: Barid Ratab2
  •  In classical text, Tahlab classified as three types:- Hazazul Maa-Coiled, seprate Ghazalul Maa-Filamentous, stellate Kharuz Zafade-Condensed
  •  Ra‟de (Repellant) Qabiz (Astringent) Musakkin (Analgesic) Mughalliz (Concentrative) Muhallil e- Auram (Anti-inflammatory) Habisuddam (Haemostatic) Mudammil (Cicatrizant) Jali (Detergent) Mubarrid (Refrigerant)
  •  Ziabetus Shakri Salabate Tehal Salabate Asab Niqris Wajaul Mafasil Surkhbada Indamale Qurooh
  •  Sailanuddam Safravi Ishal Qooba Fataqul Am‟a Qeel‟a Sud‟a Riqqate Mani
  •  Muzir: Aza‟e Barida ke liye Musleh: Tukhme Rihan (Oscimum sanctum) Badal: Haiyul Aalam (Vincea rosea) Tukhme Khurfa (Portulacca oleracea) Miqdare Khoorak: 5-7 Masha. Ashkal e- Advia: Safoof Murakkabat: NA
  •  Definition Classification Historical background Introduction Chemical Constituents Therapeutic Uses Clinical Studies Side effects Conclusion Thank You
  • “Eat to live but dont live to eat”.
  •  Spirulina (Algae) were the first life form on earth. Often, when we are searching for something new, something with special properties, we tend to completely miss what is right in front of us. “All diseases are curable but not all patients because they are very much impatient”.
  •  As living proof of Spirulina as a complete food, an old Japanese philosopher was claimed to have lived exclusively on Spirulina for 15 years! The spirulina always was and still is the main source of oxygen production. It is estimated that 70% of the total free oxygen on our planet is produced by algae.
  •  Spirulina is a single cell a microscopic filamentous aquatic cyanobacterium (Blue Green Algae) or, spiral shaped, vegetable, bacteria. The name spirulina comes from a Latin word meaning tiny spiral.
  •  Phylum- Cyanobacteria Class- Cyanophyceae Order- Oscillatoriales Genus- Spirulina, Arthrospira Species- platensis maximaNote:- There are several species of spirulina. The ones most commonly used in medicinal/nutritional supplements are Spirulina platensis and Spirulina maxima.
  •  Spirulina, The Earth First Food An ancient super food for a modern world, made from SUN, AIR, WATER & EARTH (Anaseer-e-Arba) Since the Dawn of the time. It has a long history of use as food. There are reports that it was used as food in Mexico during the Aztec civilization some 400 years ago.
  •  It is still being used as food by the Kanembu tribe in the Lake Chad area of the Republic of Chad where it is sold as dried bread called “DIHE.” The first written records of the food source go back to the year 1524. The first dried Spirulina product available was in health food stores in the United States in 1979.
  • If you walk two steps towards“ Nature, Nature would comeFour steps towards you”.
  •  Commercial algae are normally produced in large outdoor ponds under controlled conditions. Current production of Spirulina worldwide is estimated to be about 3,000 metric tons.
  •  Today, Spirulina is produced in over 22 countries including the US that has the world‟s largest Spirulina farm Earthrise in Irvine, California and is used in over 77 countries. Spirulina‟s safety as food has been established through centuries of human use and through numerous and rigorous toxicological studies.
  •  Authenticity of by UNO in its World Food Conference of 1974 declared Spirulina as the “ Best Food-for tomorrow ”. WHO has hailed Spirulina “ the greatest super food on earth ”. NASA declare1 kg of Spirulina nutritionally equal to 1000 kgs of assorted vegetables and the best food for Astronauts.
  • Food Type Crude Protein %Spirulina powder 65-70Whole Dried egg 47Beer Yeast 45Skimmed powdered milk 37Whole soybean flour 36Parmesan Cheese 36Wheat germ 27Peanuts 26Chicken 24Fish 22Beef meat 22
  • Vitamins mg 100 g-1Provitamin A 2.330.000 IU kg –1(β-carotene) 140Vitamin E 100 a-tocopherol equiv.Thiamin B1 3.5Riboflavin B2 4.0Niacin B3 14.0Vitamin B6 0.8Vitamin B12 0.32Folic acid 0.01Biotin 0.005Phantothenic acid 0.1Vitamin K 2.2
  • Fatty acid Fatty acids (%)Myristic acid 0.23Palmitic acid 46.07Palmitoleic acid 1.26Oleic acid 5.26Linoleic acid 17.43Linolenic acid 8.87Others 20.88
  • Mineral mg 100g-1Calcium 700Chromium 0.28Copper 1.2Iron 100Magnesium 400Manganese 5.0Phosphorus 800Potassium 1400Sodium 900Zinc 3.0
  • Pigments mg 100g-1Carotenoids 370Chlorophyll a 1000Phycocyanin 14000
  •  Let your food be your medicine, Hippocrates “Food is your Fate, Future, & Fortune”. Spirulina produced by the corporations in the US meets the US Food and Drug Administration (FDA) approval. The WHO estimates there are 178 million children that are malnourished across the globe, and at any given moment, 20 million suffering from the most severe form.
  •  AARP Magazine, the world‟s highest circulation magazine produced by the American Association of Retired People rates Spirulina as „No. 1 food that can add years to your life.‟ Sep-Oct 2006 issue. If athletes consumes spirulina daily,they could run up to 100 miles per day. Marathon runners use this.
  •  Spirulina is an ideal medium for food fortification to eradicate malnutrition because; • Holistic Nutrition as a Food Supplement • Cost Effective • Easily assimilated in Human Body • Safely administered to Children • Environment Friend • Easy to Transport • Long Shelf Life • Ideal Empowerment Tool for Developing Countries.
  • 1. Spirulina by countering and eradicating malnutrition plays a significant role in the achievement of the United Nations Millennium Development Goals.
  •  “Control the risk factors before they control you”. Hippocrates said Nature itself is the best physician. Treatment with spirulina in diabetic patients increased the hexokinase activity and decreased the glucose-6-phosphatase activity. The activities of enzymes suggest that enhanced lipid metabolism during diabetes is shifted towards carbohydrate metabolism and it enhances the utilization of glucose at peripheral sites.
  •  It contain insulin(Razique and Anzar et al,2012). Spirulina, potentiate the pancreatic secretion of insulin from islet β-cell or due to enhanced transport of blood glucose to the peripheral tissue. The antihyperglycemic effect of spirulina may be due to the down-regulation of NADPH and NADH, a cofactor in the fat metabolism. One of the possible actions of spirulina may be due to its inhibition of endogenous synthesis of lipids.
  •  Spirulina contains compounds like phycocyanin, polysaccharides,and sulfolipids that enhance the immune system. It have a major impact on the immune system by increasing the: phagocytic activity of macrophages, stimulating the NK cells activate and mobilize the T and B cells inhibitory effect on the release of histamine from mast cells. The immunostimulatory effects of spirulina on TNF- α play a major role in precipitating autoimmune diseases in genetically predisposed persons.
  •  Spirulina, have phycocyanobilin which inhibits NADPH oxidase activity and promotes glutathione synthesis along with a marked production of antioxidant enzymes. Geriatric patients administered spirulina for 16 weeks showed a remarkable improvement in the antioxidant potential, β-carotene is best known, an antioxidant rich. It provide functional preservation of the intestinal epithelium which acts as a first line of mucosal barrier against infections.
  •  The antioxidant and immune modulation effect of Spirulina act as anticancer activity. A study at the Harvard University showed that an extract from spirulina is highly successful in the treatment of cancer. Phycotene, destruct the tumour cell/control tumour cells and also arrest their growth. Mathew et al,(1995) who studied the effect of Spirulina on oral leukoplakia (a precancerous lesion) in pan tobacco chewers in Kerala (44 subjects).
  •  The apoprotein component of phycocyanin was responsible for the inhibition of COX-2 in rheumatoid arthritis. Phycocyanin through its ability to efficiently scavenge free radicals and inhibit lipid peroxidation. inflammation reduction in arthritis patients due to the stimulation to secrete IL-2 which regulates inflammatory response.
  •  Sulfated polysaccharide, calcium spirulan inhibit the replication of several viruses, Especially those with an envelope such as the measles virus, and the HIV-1 virus etc. Chelating property of calcium in the inhibition the replication of virus. Spirulina has been found to improve weight gain and correct anaemia in both HIV-infected and HIV-negative cases.
  •  Spirulina showed a significant reduction of the LDL to HDL ratio after four months of supplementation. 15 male voluteers taking 4.2 gm/day for 4 weeks statically significant reduction in LDL cholesterol (p<0.05). 4 g/day spirulina taking in IHD patients,significantly lowered blood cholesterol, triglycerides, LDL & VLDL cholesterol and higher HDL. Spirulina also decrease blood pressure by promoting vasodilation and restricting vasoconstriction.
  •  Effect of Spirulina supplementation in the management of Bronchial Asthma (2001). Hypocholesterolemic effect of Spirulina on obese women (April 2000). Effect of Spirulina as a Nutritional Supplement on Malnourished Children (December 1999). Evaluation of Chemoprevention of Oral Cancer with Spirulina (1995).
  •  Effect of Spirulina supplementation on Vitamin A status during pregnancy (March 1995). Eeffect of Spirulina Supplementation on Vitamin A status During Pregnancy and Lactation (September 2001). Role of Beta-carotene in the management of Oral Submucous Fibrosis (1994). Beta-carotene Therapy for Tropical Pancreatitis (October 1991).
  •  Effect of supplementation of Spirulina on the levels of blood glucose and lipid profile of NIDDM (August 1991). Impact of Spirulina supplementation on anaemic adolescent girls (14–16) years (May 2000). A study of haemoglobin levels in humans fed on Spirulina supplement (June 1990).
  •  A Study on the synergistic Effect of Spirulina and β -carotene on subjects with Rheumatoid Arthritis (April 2002). Efficacy of Spirulina in a case of rheumatoid arthritis (1992). Effect of Spirulina supplementation on hypercholesterolemic patients (April 1994). Effect of Supplementaion of Spirulina on Diabetic and Hyperlipidemic Patients (May 2000). A Study on the “Anti-stress activity of Spirulina platensis” (Dec 2001).
  •  Hypoglycaemia Constipation Upset stomach, Nausea Gastric over acidity Hiccups, mild diarrhoea Feeling hungry