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Practical pathology revision 4th year 1st term 2013 miro
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Practical pathology revision 4th year 1st term 2013 miro Presentation Transcript

  • 1. Revision
  • 2. .Organ :- Intestine-Disease :- Para T.B- .Stain :- H & E-Lesion :- The intestinal mucosa is filled with-macrophages , giant cells and lymphocytes((granulomatous reaction
  • 3. Paratuberculosis
  • 4. paratuberculosisOrgan: intestineStain: Ziehl Neelsenlesion: the acid-fast bacilli is seen in the intestinal mucosa
  • 5. Paratuberculosis
  • 6. organ :- Endometrium--Stain :- H & E-Disease :- Brucellosis-Lesion :- severe endometritis represented bypreglandular round cell infiltration necroticendometeritis ch. By necrotic epi. + Adhesion .with few infl. Cell infiltration
  • 7. Brucellosis
  • 8. organ :- Endometrium--Stain :- H & E-Disease :- Brucellosis-Lesion :- severe endometritis represented bypreglandular round cell infiltration +Edema
  • 9. Brucellosis
  • 10. .Organ :- liver- .Stain :- H & E- .Disease :- Brucellosis-Lesion :- presence of pyogranuloma-characterized by presence of Caseous necrosissurrounded by epithelioid cells , giant cellsand neutrophils then enclosed by fibrous C.T
  • 11. Brucellosis
  • 12. .Organ :- liver- .Stain :- H & E- .Disease :- Brucellosis-Lesion :- presence of pyogranuloma-characterized by presence of Caseous necrosissurrounded by epithelioid cells , giant cellsand neutrophils then enclosed by fibrous C.T
  • 13. Brucellosis
  • 14. .Organ :- liver- .Stain :- H & E- .Disease :- Brucellosis-Lesion :- presence of pyogranuloma-characterized by presence of Caseous necrosissurrounded by epithelioid cells , giant cellsand neutrophils then enclosed by fibrous C.T
  • 15. Brucellosis
  • 16. .Organ :- Lung-Stain :- H & E-Disease :- T.B-Micro :- Granulomatous reaction + calcification- .in center
  • 17. Tuberculosis
  • 18. .Organ :- Lymph node-.Stain :- H & E-Disease :- T.B-Micro :- Granulomatous reaction + caseation &-.calcification
  • 19. Tuberculosis
  • 20. .Organ :- Kidney-Stain :- H & E-Disease :- T.B- .Micro :- Granulomatous reaction + Giant cells-
  • 21. Tuberculosis
  • 22. Tuberculosis
  • 23. .Organ :- Lung- .Stain :- H & E- .Disease :- Pneumonic pasteurellosis-Lesion :- Fibrous bronchopneumonia-characterized by filling of alveoli withserofibrinous exudate infiltrated withneutrophils and macrophages , congestion of interalveolar capillaries and hemorrhage
  • 24. Pasteurellosis
  • 25. .Organ :- Lung- .Stain :- H & E- .Disease :- Pneumonic pasteurellosis-Lesion :- Fibrous bronchopneumonia-characterized by filling of alveoli withserofibrinous exudate infiltrated withneutrophils and macrophages , congestion of interalveolar capillaries and hemorrhage
  • 26. Pasteurellosis
  • 27. Pneumonic pasteurellosis.Organ :- Lung-.Stain :- Silver stain-.Disease :- Pneumonic pasteurellosis-Lesion :- Blackish stained P.hemorrage freely-inside alveolar lumen & trapped intra-alveolar.macrophage
  • 28. Pasteurellosis
  • 29. .Organ :- Lung- .Stain :- IHC- .Disease :- pneumonic pasteurellosis-Lesion :- Positive brown immunolabelling-against P.multocida mainly inside cytoplasm .of macrophages infiltrating lumen of alveoli
  • 30. Pasteurellosis
  • 31. Pasteurellosis
  • 32. Organ :- Spinal cord-Stain :- H & E- ( Disease :- Actinomycosis ( A.pyogenes-Lesion :- Consists of centrally located bacterial-colonies surrounded by number of neutrophil,lymphocyte & epithelioid cells all surroundedby Fibrous C.T
  • 33. Actinomyces pyogenes A. pyogenes
  • 34. Actinomyces pyogenes
  • 35. Organ :- Spinal cord-Stain :- H & E- ( Disease :- Actinomycosis ( A.pyogenes-Lesion :- Consists of centrally located bacterial-colonies surrounded by number of neutrophil,lymphocyte & epithelioid cells all surroundedby Fibrous C.T
  • 36. Actinomyces pyogenes
  • 37. Actinomyces pyogenes
  • 38. Actinomyces pyogenes
  • 39. Actinomyces pyogenes
  • 40. Actinomyces pyogenes
  • 41. Organ :- Intestine- (Stain :- IHC ( ImmunoHistoChemestry- Lesion :- Lowsenia enteritis-Micro :- Brown stained lowsenia enteritis in-lamina propria & in between intestine villi
  • 42. Lawsonia intracellularis
  • 43. Organ :- Intestine- (Stain :- IHC ( ImmunoHistoChemestry- Lesion :- Lowsenia enteritis-Micro :- Brown stained lowsenia enteritis in-lamina propria & in between intestine villi
  • 44. Lawsonia intracellularis
  • 45. .Organ :- Lung-.Disease :- Avian influenza-Micro :- Congestion, perivascular edema &-.fibrosis
  • 46. Avian influenza -Lung
  • 47. Avian influenza - Spleen
  • 48. Avian influenzaOrgan: spleen Stain: H &E Disease: Avian influenzaLesion: hemorrhage , congestion & hemolysis of red pulp
  • 49. Avian influenza ( High power of ( spleen
  • 50. Avian influenzaOrgan: lung Stain: H &E Disease: Avian influenzaLesion: congestion, haemorrhage and hemosiderosis
  • 51. Avian influenza
  • 52. Organ :- Heart-Stain :- H & E-Disease :- Leukosis sarcoma-Micro :- Focal invasion & replacement of-myocardium with pleomorphic leukocytes
  • 53. Avian leukosis
  • 54. .Organ :- Intestine- .Stain :- H&E- .Disease :- Intestinal coccidiosis-Micro :- Various developmental stages of-coccidia were seen in the epithelial lining ofintestinal crypts (arrow) or free in lamina( .propria besides extravasated RBCs (arrow
  • 55. Intestinal coccidiosis
  • 56. Intestinal coccidiosis
  • 57. Intestinal coccidiosis
  • 58. .Organ :- Intestine- .Stain :- H & E- .Disease :- Ascariasis-Lesion :- Presence of adult worm in the lumen- .of intestine with desquamation of epithelium
  • 59. Fowl Ascariasis
  • 60. dermatophytosis• Organ: skin• Lesion:- dermatophytosis• Stain: H&E• Micro: severe inflammatory in skin beside loss of hair shaft and ectothrix
  • 61. Dermatophtosis
  • 62. Dermatophtosis – Hair follicle
  • 63. .Organ :- Lung-.Stain :- PAS-.Disease :- Dermatophytosis-Micro :- PAS + hyphae are seen in skin-( .( Brownish color
  • 64. .Organ :- Lung- .Stain :- H & E- .Disease :- Aspergillosis-Micro :- severe pneumonia appear as dense-rounded fosci eosinophilic center beside .granulomatous reaction
  • 65. Aspergillosis
  • 66. .Organ :- Intestine-Disease :- Para T.B- .Stain :- H & E-Lesion :- The intestinal mucosa is filled with-macrophages , giant cells and lymphocytes((granulomatous reaction
  • 67. paratuberculosis - 9
  • 68. Organ :- spleen-Stain :- H & E-Disease :- Brucellosis-Micro :- pyogranulomatous spleen represented-by aggregation of mononuclear cells,epithelioid cells & neutrophil
  • 69. .Organ :- liver- .Stain :- H & E- .Disease :- Brucellosis-Lesion :- presence of pyogranuloma-characterized by presence of Caseous necrosissurrounded by epithelioid cells , giant cellsand neutrophils then enclosed by fibrous C.T
  • 70. Brucellosis-17
  • 71. Pneumonic pasteurellosis.Organ :- Lung-.Stain :- Silver stain-.Disease :- Pneumonic pasteurellosis-Lesion :- Blackish stained P.hemorrage freely-inside alveolar lumen & trapped intra-alveolar.macrophage
  • 72. Pneumonic pasteurellosis silver stain
  • 73. .Organ :- Lung- .Stain :- H & E- .Disease :- Pneumonic pasteurellosis-Lesion :- Fibrous bronchopneumonia-characterized by filling of alveoli withserofibrinous exudate infiltrated withneutrophils and macrophages , congestion of interalveolar capillaries and hemorrhage
  • 74. Pneumonic pasteurellosis H & E-6
  • 75. .Organ :- Lung- .Stain :- IHC- .Disease :- pneumonic pasteurellosis-Lesion :- Positive brown immunolabelling-against P.multocida mainly inside cytoplasm .of macrophages infiltrating lumen of alveoli
  • 76. Pneumonic pasteurellosis IHC- 7
  • 77. Pneumonic pasteurellosis IHC- 7
  • 78. Organ :- Lung-Stain :- H & E-Disease :- Avian influenza-Micro :- Congestion & infiltration with-mononuclear cell in the interstitial tissue
  • 79. Lung - Avian influenza
  • 80. Organ :- Heart-Stain :- H & E-Disease :- Leukosis sarcoma-Micro :- Focal invasion & replacement of-myocardium with pleomorphic leukocytes
  • 81. Heart - Leukosis sarcoma
  • 82. Organ :- Spleen-Stain :- H & E-Disease :- Avian influenza-Micro :- Periarteriolar edema & necrosis of- lymphoid tissue
  • 83. Spleen - Avian influenza
  • 84. Organ :- Spinal cord-Stain :- H & E- ( Disease :- Actinomycosis ( A.pyogenes-Lesion :- Consists of centrally located bacterial-colonies surrounded by number of neutrophil,lymphocyte & epithelioid cells all surroundedby Fibrous C.T
  • 85. (Actinomycosis ( A.pyogenes
  • 86. (Actinomycosis ( A.pyogenes
  • 87. Organ :- Intestine- (Stain :- IHC ( ImmunoHistoChemestry- Lesion :- Lowsenia enteritis-Micro :- Brown stained lowsenia enteritis in-lamina propria & in between intestine villi
  • 88. Lowsenia enteritis
  • 89. .Organ :- Intestine- .Stain :- H & E- .Disease :- Ascariasis-Lesion :- Presence of adult worm in the lumen- .of intestine with desquamation of epithelium
  • 90. .Organ :- Intestine- .Stain :- H&E- .Disease :- Intestinal coccidiosis-Micro :- Various developmental stages of-coccidia were seen in the epithelial lining ofintestinal crypts (arrow) or free in lamina( .propria besides extravasated RBCs (arrow
  • 91. .Organ :- Skin- .Stain :- H&E- .Disease :- Fowl pox-Micro :- The skin showed hyperplasia of prickle-cell layer which contain ICIB moreover theprickle cell layer shows hydropic degeneration.
  • 92. .Organ :- Lung-.Stain :- PAS-.Disease :- Dermatophytosis-Micro :- PAS + hyphae are seen in skin-( .( Brownish color
  • 93. .Organ :- Skin- .Stain :- H & E- .Disease :- Dermatophytosis-Micro :- Severe inflammatory reaction-(dermatitis) in the skin besides loss of hairshaft, the presence of perifollicular ectothrix, . arthrospores & hyperkeratosis
  • 94. .Organ :- Lung- .Stain :- H & E- .Disease :- Aspergillosis-Micro :- severe pneumonia appear as dense-rounded fosci eosinophilic center beside .granulomatous reaction