Engineering to sustain
Clostridia and n-butanol - Multi-marketplatforms for profitable introduction ofcommodity scale renewable chemicals
Mission and HistoryElcriton is inventing and commercializing technologies tosupplant fossil fuel consumption, reduce green...
Mission and History  All non-dilutive funding and profitable by              the end of 2011.History:•Evolved out of the a...
Two platforms, numerousmarketsHO                     • Specialty chemical                       • Biofuel (i.e., gasoline ...
Specialty chemical market    >$5 (USD) billion/year n-butanol market                                                Chemic...
Market need for sustainable solutions                     Need  Driver• Cost  increased propylene costs*• Secured supply...
Case for a biofuel - >$100B marketCompared to ethanol:2.   High energy content          Butanol3.   Higher air to fuel rat...
Elcriton niche in the butanol value chain      Feedstock    Manufacture                            Distribution           ...
Sugar to n-butanol technology                            5-carbons                            (xylose)                    ...
Clostridia bioprocessing platformStrain development in clostridia and related species   • Genetic engineering technologies...
Advantages of the multi-market,platform approach• Flexibility in business model development• Early revenue generation (e.g...
Clostridia bioprocessing platformGreen – Black processing   • Remediation and upgrading of industrial waste   • Glycerol, ...
For questions please contact:    Bryan P. Tracy, PhD  15 Reads Way Suite 106   New Castle, DE 19720 BryanTracy@elcriton.co...
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Clostridia and n-butanol - Multi-market platforms

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  • Sustainability in general refers to future generations having the same or greater access to resources as the current generation. The 3 pillars of sustainability consist of social, environmental and economic considerations. Social - human rights, labor rights, and corporate governance Environment -
  • Sustainability in general refers to future generations having the same or greater access to resources as the current generation. The 3 pillars of sustainability consist of social, environmental and economic considerations. Social - human rights, labor rights, and corporate governance Environment -
  • Sustainability in general refers to future generations having the same or greater access to resources as the current generation. The 3 pillars of sustainability consist of social, environmental and economic considerations. Social - human rights, labor rights, and corporate governance Environment -
  • Sustainability in general refers to future generations having the same or greater access to resources as the current generation. The 3 pillars of sustainability consist of social, environmental and economic considerations. Social - human rights, labor rights, and corporate governance Environment -
  • Sustainability in general refers to future generations having the same or greater access to resources as the current generation. The 3 pillars of sustainability consist of social, environmental and economic considerations. Social - human rights, labor rights, and corporate governance Environment -
  • Sustainability in general refers to future generations having the same or greater access to resources as the current generation. The 3 pillars of sustainability consist of social, environmental and economic considerations. Social - human rights, labor rights, and corporate governance Environment -
  • Sustainability in general refers to future generations having the same or greater access to resources as the current generation. The 3 pillars of sustainability consist of social, environmental and economic considerations. Social - human rights, labor rights, and corporate governance Environment -
  • Sustainability in general refers to future generations having the same or greater access to resources as the current generation. The 3 pillars of sustainability consist of social, environmental and economic considerations. Social - human rights, labor rights, and corporate governance Environment -
  • Clostridia and n-butanol - Multi-market platforms

    1. 1. Engineering to sustain
    2. 2. Clostridia and n-butanol - Multi-marketplatforms for profitable introduction ofcommodity scale renewable chemicals
    3. 3. Mission and HistoryElcriton is inventing and commercializing technologies tosupplant fossil fuel consumption, reduce green house gasemissions, and accelerate the expansion of cleantechindustries.History:•Evolved out of the academic laboratory of Professor TerryPapoutsakis University of Delaware in 2009 - Bryan Tracy namedCEO is PI on research grants that seeded company•2011 – license technology to the world’s largest biobutanolproducer•2012 – Will sign a strategic partnership for development andintegration of hydrolysis technology and potentially for novelseparation technology
    4. 4. Mission and History All non-dilutive funding and profitable by the end of 2011.History:•Evolved out of the academic laboratory of Professor TerryPapoutsakis University of Delaware in 2009 - Bryan Tracy namedCEO is PI on research grants that seeded company•2011 – license technology to the world’s largest biobutanolproducer•2012 – Will sign a strategic partnership for development andintegration of hydrolysis technology and potentially for novelseparation technology
    5. 5. Two platforms, numerousmarketsHO • Specialty chemical • Biofuel (i.e., gasoline n-butanol alternative and Jet A or JP-8) • Chemical production • Waste stream remediation & upgrading • Exotic applications - CDEPT Clostridia geneticengineering & bioprocessing
    6. 6. Specialty chemical market >$5 (USD) billion/year n-butanol market Chemical feedstock •Glycol ethers (17%) •Butyl acetate (21%) •Butyl acrylate (39%) Uses Product formulations •Paints/Primers •Cosmetics •Lubricating oils •Etc.
    7. 7. Market need for sustainable solutions Need  Driver• Cost  increased propylene costs*• Secured supply chains  unstable propylene supply• Increasing demand (11.9% CAGR)  emerging markets• Green solutions  Preferred buyer opportunities• New & MUCH BIGGER market opportunities  gasoline alternatives & jet fuel
    8. 8. Case for a biofuel - >$100B marketCompared to ethanol:2. High energy content Butanol3. Higher air to fuel ratio Better MPG4. Lower heat of vaporization5. Less hygroscopic6. Less corrosive to gasoline FLEXFUEL infrastructure7. Blending synergies with ethanol
    9. 9. Elcriton niche in the butanol value chain Feedstock Manufacture Distribution or Off-take Mechanical Hydrolysis Separation/ prep. Purification Pretreat- Fermentation ethanol/ ment acetone butanol heat/ energy HO enzyme clostridia gas Pretreatment & Conversion the Separations Hydrolysis Elcriton way
    10. 10. Sugar to n-butanol technology 5-carbons (xylose) 6-carbons (glucose) +starch hemicellulose Metabolic Engineering Considerations: Molecular-scale solutions to •What’s it eating? multi-million dollar •How fast should they grow? •Can I reduce byproduct production? bioprocessing impediments •Can I integrate with purification? •Can they tolerate hydrolysis byproducts? •Can I shift production to another feedstock?
    11. 11. Clostridia bioprocessing platformStrain development in clostridia and related species • Genetic engineering technologies • Opportunities for related, desirable speciesSynthetic biology • Novel pathways for new chemicals • Opportunities in chemolithotrophic clostridiaBioprocess development & integration • Concurrent strain and bioreactor development • Bioreactor and purification integration
    12. 12. Advantages of the multi-market,platform approach• Flexibility in business model development• Early revenue generation (e.g., licensing)• Demonstration of commercial credibility = de-risking larger market opportunities• Opportunities for Non-recurring revenues (NRR)• Bootstrapping opportunities• Reduce dilution in early rounds of fund raising• Increase value proposition• Expand options of later stage financing (e.g., debt financing)
    13. 13. Clostridia bioprocessing platformGreen – Black processing • Remediation and upgrading of industrial waste • Glycerol, flue gases, methane and ag wastesGaseous fermentations • Chemolithotropic fermentations • Ideally CO2 to specialty chemicals – H2?Renewable H2 production • Photosynthetic & CO2 sequestration • Algal photobioreactor & dewatering systems – DOE and ARPA-E
    14. 14. For questions please contact: Bryan P. Tracy, PhD 15 Reads Way Suite 106 New Castle, DE 19720 BryanTracy@elcriton.com 302-220-4760 864-921-5146

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