Genes

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Gene Therapy&GMO's

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Genes

  1. 1. Genes
  2. 2. GeneDeoxyribonucleic acid (DNA) isthe chemical informationdatabase that carries thecomplete set of instructions forthe cell as to the nature of theproteins produced by it, its lifespan, maturity, function anddeath. Genes are the workingsubunits of DNA. Each genecontains a particular set ofinstructions, usually coding for aparticular protein or for aparticular function.
  3. 3. What is Gene Therapy?Gene therapy is anexperimental technique usedin treatment of malfunctioninggenes, whereby a deficient ordefective gene is replaced by aworking gene, so that thebody can make the properenzyme or protein and as aresult eliminate the origin ofthe disease.
  4. 4. Vector(viruses) are using in Gene TherapyTo insert the corrected geneinto the patient’s targeted cell,a carrier molecule, called avector must be used. The mostcommon form of vector is avirus.The viruses are modifiedby replacing the deformed genewith the genes encoding for thedesired effect.Thus the viruscan be used as a vehicle tocarry the good genes into thetargeted human cell.
  5. 5. How does Gene Therapy work?The target cells areusually a patient’s liveror lung cells, where theviral vector transfers thetherapeutic gene into thetarget cell. Thetherapeutic genegenerates the productionof functional proteins andrestores the cell to itsnormal state.
  6. 6. Genetically modified organismA genetically modifiedorganism (GMO) is anorganism whose geneticmaterial has been altered usinggenetic engineeringtechniques. Organisms thathave been genetically modifiedinclude micro-organisms suchas bacteria and yeast, plants,fish, and mammals. GloFish, the first genetically modified animal
  7. 7. Genetically Modified Foods:Harmful or Helpful? The health consequences of eating genetically modified organisms are largely unknown. GMOs require massive amounts of pesticides, herbicides and fungicides. Significantly high kidney and liver toxicity after only 90 days in laboratory rats that were fed GM corn.

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