Barcelona 2014: CrossRef Tools for Small Publishers by Geoffrey Bilder

1,119 views

Published on

Published in: Business
0 Comments
0 Likes
Statistics
Notes
  • Be the first to comment

  • Be the first to like this

No Downloads
Views
Total views
1,119
On SlideShare
0
From Embeds
0
Number of Embeds
13
Actions
Shares
0
Downloads
5
Comments
0
Likes
0
Embeds 0
No embeds

No notes for slide

Barcelona 2014: CrossRef Tools for Small Publishers by Geoffrey Bilder

  1. 1. Geoffrey Bilder Director of Strategic Initiatives Barcelona, 2014 CrossRef Helps Small Publishers
  2. 2. Who am I?
  3. 3. Let’s play a game...
  4. 4. Part II
  5. 5. BrandIs it relevant? Is it good? Is it important? provenanceinfrastructure •What is it? •Where can I get it? •What refers to it? •What does it refer to? •What has been done to it? •Who provides stewardship of it? •Who funded it? •What can I do with it? •Who do we credit it to? •What are their credentials?
  6. 6. CrossRef DOIs
  7. 7. http://www.easel.com/foo/bar/blat.html Tim Berners-Lee (1998). "Cool URIs Don’t Change" Litigation Transfer Poverty Forgetfulness Divorce Death...
  8. 8. List of university and college mergers in the United States From Wikipedia, the free encyclopedia This is a list of mergers of universities and/or colleges in the United States with the name of the surviving institution, predecessors, and effective date. This list is incomplete; you can help by expanding it (http://en.wikipedia.org/w/index.php? title=List_of_university_and_college_mergers_in_the_United_States&action=edit) . Contents 1 A through D 2 E through M 3 N through Z 4 See also 5 References A through D Alliant International University - merger of California School of Professional Psychology and United States International University, 2001 Azusa Pacific College - absorbed Arlington College, 1968 Azusa Pacific College - merger of Azusa College and Los Angeles Pacific College, 1965 University of Baltimore - absorbed Eastern College, 1970 Benedictine College - merger of Mount Saint Scholastica College and St. Benedict's College - 1971 Boston University School of Medicine - absorbed Boston Female Medical School, 1874 Brevard College - merger of Brevard Institute, Weaverville College, and Rutherford College, 1934 University of California, Berkeley - merger of the College of California and the Agricultural, Mining, and Mechanical Arts College, 1853 Carson-Newman College - merger of Carson College and Newman College for Women, 1889 Case Western Reserve University - merger of Case Tech and Western Reserve, 1971-72 The Catholic University of America - absorbed Columbus University, 1954 Central Nazarene College - absorbed Nazarene Bible Institute (1911) Chicago College of Performing Arts - absorbed Roosevelt University School of Music, 1954 University of Cincinnati - absorbed Medical College of Ohio 1896; Cincinnati College of Pharmacy, 1954 Clark Atlanta University - merger of Clark College and Atlanta University, 1988 Davenport University - merger of Davenport College, Detroit College of Business, and Great Lakes College, 2000. University of Delaware - merger of Newark College and Women's College of Delaware, 1921 DePaul University - absorbed Barat College, 2001 List of university and college name changes in the United States From Wikipedia, the free encyclopedia Here follows a list of renamings of universities and colleges in the United States. Contents: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z Top of Page — See also Current Name Former Name(s) Year of Change Alabama Agricultural and Mechanical University Agricultural and Mechanical College of Alabama Alcorn State University Alcorn Agricultural and Mechanical College 1974 Amridge University Southern Christian University Alliant International University California Western Appalachian State University Appalachian State Teachers College; Appalachian Training School for Teachers; Appalachian State Normal School; Watauga Academy 1967 [1] Apollo College American Institute of Health Technology 2005 [2] Arcadia University Beaver College 2001 Arizona State University Tempe Normal School 1958 University of North Texas Libraries CyberCemetery Home Search the CyberCemetery Browse the CyberCemetery Related Resources Contact Us Digital Collections Home Browse the CyberCemetery: Agencies by Date Expired 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1995 2009 National Prison Rape Elimination Commission (August 2009) 2008 Citizens' Health Care Working Group (June 2008) 2007 Antitrust Modernization Commission (May 2007) 2006 Texas Tax Reform Commission (March 2006) 2005 Select Bipartisan Committee to Investigate the Preparation for and Response to Hurricane Katrina (December 2005) President's Advisory Panel on Federal Tax Reform (November 2005) Commission on Systemic Interoperability (October 2005) Commission on Review of Overseas Military Facility Structure of the United States: Overseas Basing Commission (August 2005) Return to Flight Task Group (August 2005) White House Conference on Cooperative Conservation (August 2005) Commission on the Intelligence Capabilities of the United States Regarding Weapons of Mass Destruction (March 2005) University of North Texas Libraries Government Documents Dept. P.O. Box 305190 Denton, TX 76203-5190 Phone: (940) 565-2870 Fax: (940) 565-2599 http://www.library.unt.edu/govinfo Geographical renaming From Wikipedia, the free encyclopedia Geographical renaming is the act of changing the name of a geographical feature or area. This can range from the uncontroversial change of a street name to a highly disputed change to the name of a country. Some names are changed locally but are not recognised by other countries, especially when there is a difference in language. Other names may not be officially recognised but remain in common use. There are many reasons to undertake renaming, with political motivation being the primary cause, such as renaming places to honour Stalin, and reverting to the original names (see de-Stalinization). One of the most common reasons for a country changing its name is newly acquired independence. When borders are changed, sometimes due to a country splitting or two countries joining together, the name of the areas can change. This, however, is more the creation of a different entity than an act of geographical renaming. Other more unusual reasons for renaming have included: To stop having an unusual or embarrassing name As part of a sponsorship deal or publicity stunt A change might see a completely different name being adopted or may simply be just a slightly different spelling. In some cases established institutions preserve the old names of the renamed places in their names, such as the Pusan National University in Busan, South Korea; the Peking University in Beijing, People's Republic of China; Bombay Stock Exchange, IIT Bombay and the Bombay High Court in Mumbai, Republic of India; Persian Gulf, south of Iran (formerly Persia); and the University of Madras, Madras Stock Exchange, the Madras High Court, and IIT Madras in Chennai, Republic of India. U.N. Member States U.S. State Department List of Independent States Mapping.com's list of Worldwide Country and City Name Changes Since 1990 Internet Domains from the Internet Assigned Numbers Authority (an agency under ICANN, the Internet Corporation for Assigned Names and Numbers) All the Airport Codes In The World (about 36,000 codes!) ISO3166-defined country codes 240 2- letter codes, 3-letter codes, and RIPE NCC Service Region Flags of the World, and other information, keyed to each country's ISO3166 Code Country Information from the CIA World Name Changes Since 1990: Countries, Cities, and More An admittedly incomplete and imperfect list of new countries and cities, and various name changes Search For Cities and Countries Not Listed Here: Search Web mapping.com 1. "New" Countries Since 1990 FORMER USSR: Estonia Latvia Lithuania Belarus Ukraine Moldova Georgia Armenia Cheap International Calls Get A Free Lebara SIM (Was £2.99) Limited Offer - Order Yours Online! www.Lebara-Mobile.co.uk Montenegro Property Choose from over 185,000 properties at the UK's leading holiday portal! Holiday-Rentals.co.uk country brand positioning Acanchi, founded by Fiona Gilmore, specialists in country positioning. www.acanchi.com Russian River Cruises The only 5-star vessel on the Russian waterways www.exeterinternational.com
  9. 9. http://www.foo.com
  10. 10. http://www.txt2pic.com/
  11. 11. PQ7797.B635.B5213 2000 (persistent catalog #) (current physical location) Hayden Library, 3rd floor, shelf # 53 The Renear/Palmer article states.... http://dx.doi.org/10.1002/meet.2009.1450460141 http://www.sciencemag.org/cgi/doi/10.1126/science.1157784 (persistent URI) (current web location) Library card catalog maps catalog# to current physical location of content CrossRef maps DOI to current web location of content
  12. 12. • PURL • XRI • Numly Numbers • NOIDs • URL Shorteners ?
  13. 13. “Persistence” isn’t a technical issue, it is a social issue. “CrossRef links are as persistent as CrossRef staff”
  14. 14. • Members must assign DOIs and deposit metadata • Members are expected to assign DOIs and deposit metadata on a current basis (i.e. content should be deposited in CrossRef as soon as possible after being published) • Members have an obligation to maintain the metadata and URLs associated with all registered DOIs. • Members have an obligation to link references in the journal articles they deposit via CrossRef • Before a member may retrieve DOIs for references in an article from a particular journal, the member must be depositing articles from that journal on a current basis. • DOI-routed reference links enabled by CrossRef must resolve to a response page containing no less than complete bibliographic information about the target content, with information about how the content can be acquired and/or a hyperlink leading to the content itself.
  15. 15. CrossRef Demographics
  16. 16. < $1 million revenue $275 annual membership fee 80% members are “small” publishers
  17. 17. New CR Members are • Small • Open Access • From BRIC or Developing Countries
  18. 18. Reduce Financial Burden
  19. 19. Other options • Continue to hold line on fees • More sponsoring entities and service providers • Bundle DOIs with membership
  20. 20. Reduce Technical Burden
  21. 21. Members have an obligation to link references in the journal articles they deposit via CrossRef. http://goo.gl/ZV3t3l
  22. 22. Cited By
  23. 23. Helping The Small Publisher
  24. 24. Depositor Tools
  25. 25. Investigation of the Staphylococcus aureus GraSR Regulon Reveals Novel Links to Virulence, Stress Response and Cell Wall Signal Transduction Pathways Me´lanie Falord1,2 , Ulrike Ma¨der3 , Aure´lia Hiron1,2 , Michel Dbarbouille´1,2 , Tarek Msadek1,2 * 1 Institut Pasteur, Biology of Gram-Positive Pathogens, Department of Microbiology, Paris, France, 2 CNRS, URA 2172, Paris, France, 3 Interfaculty Institute for Genetics and Functional Genomics, Department for Functional Genomics, Ernst Moritz Arndt University, Greifswald, Germany Abstract The GraS/GraR two-component system has been shown to control cationic antimicrobial peptide (CAMP) resistance in the major human pathogen Staphylococcus aureus. We demonstrated that graX, also involved in CAMP resistance and cotranscribed with graRS, encodes a regulatory cofactor of the GraSR signaling pathway, effectively constituting a three- component system. We identified a highly conserved ten base pair palindromic sequence (59 ACAAA TTTGT 39) located upstream from GraR-regulated genes (mprF and the dlt and vraFG operons), which we show to be essential for transcriptional regulation by GraR and induction in response to CAMPs, suggesting it is the likely GraR binding site. Genome-based predictions and transcriptome analysis revealed several novel GraR target genes. We also found that the GraSR TCS is required for growth of S. aureus at high temperatures and resistance to oxidative stress. The GraSR system has previously been shown to play a role in S. aureus pathogenesis and we have uncovered previously unsuspected links with the AgrCA peptide quorum-sensing system controlling virulence gene expression. We also show that the GraSR TCS controls stress reponse and cell wall metabolism signal transduction pathways, sharing an extensive overlap with the WalKR regulon. This is the first report showing a role for the GraSR TCS in high temperature and oxidative stress survival and linking this system to stress response, cell wall and pathogenesis control pathways. Citation: Falord M, Ma¨der U, Hiron A, De´barbouille´ M, Msadek T (2011) Investigation of the Staphylococcus aureus GraSR Regulon Reveals Novel Links to Virulence, Stress Response and Cell Wall Signal Transduction Pathways. PLoS ONE 6(7): e21323. doi:10.1371/journal.pone.0021323 Editor: Malcolm James Horsburgh, University of Liverpool, United Kingdom Received May 4, 2011; Accepted May 25, 2011; Published July 1, 2011 Copyright: ß 2011 Falord et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Funding: This work was supported by research funds from the European Commission (StaphDynamics [LHSM-CT-2006-019064] and BaSysBio [LSHG-CT-2006- 037469] grants), the Centre National de la Recherche Scientifique (CNRS URA 2172), Agence Nationale de la Recherche (ANR GrabIron and NaBab), and the Institut Pasteur (PTR Nu256 and PTR Nu336). Me´lanie Falord received a Young Scientist Fellowship from the Conseil Pasteur-Weizmann. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing Interests: The authors have declared that no competing interests exist. * E-mail: tmsadek@pasteur.fr Introduction The opportunistic pathogen Staphylococcus aureus is both a commensal and a major Gram-positive pathogen, causing a variety of infections ranging from superficial skin abscesses to more serious diseases such as pneumonia, meningitis, endocarditis, septicemia and toxic shock syndrome [1]. The ubiquitous nature of this pathogen stems mostly from its capacity to survive a large variety of environmental conditions as well as an impressive ability to resist host innate immune defense mechanisms and produce systemic infections, often in healthy humans [2,3]. This unique adaptive potential has made S. aureus one of the major causes of nosocomial infections today, compounded by the rapid emergence of multiple antibiotic-resistant strains over the past few decades [4], particularly methicillin and vancomycin-intermediate resistant strains (MRSA and VISA). Until recently, vancomycin had remained the weapon of last resort, but the recent appearance of the enterococcal vanA vancomycin-resistance gene cluster in S. aureus highlights the growing threat this bacterium poses to human health and the urgent need for developing novel therapeutic approaches [5,6]. Cationic antimicrobial peptides (CAMPs) are an important component of host innate immunity and understanding the molecular mechanisms involved in resistance is a key factor in staphylococcal treatment research. CAMPs have both cationic and amphipathic properties and are classified according to their length and secondary structure [7]. They are produced by certain immune, skin and epithelial cells in all living kingdoms, as defenses against microbial proliferation, and many are known to act by forming pores in the cell membrane, through interactions with bacterial cell envelope components [8]. However, recent work has shown that several CAMPs, including indolicidin and colistin, can also kill by inhibiting intracellular processes such as protein and DNA synthesis as well as septum formation and division [9]. To counteract CAMP antimicrobial activity during infection, Gram-positive bacteria have developed several resistance mecha- nisms, including degradation, sequestration or electrostatic repulsion [10]. In Bacillus subtilis and related Gram-positive bacteria, D- alanylation of wall teichoic acids (WTAs) and lipoteichoic acids (LTAs), mediated by the DltABCD enzymes, as well as MprF- dependent lysylination of phosphatidylglycerol, prevent CAMP- binding by increasing the bacterial surface positive charge [10,11]. Two-component systems (TCSs) play an important role in these mechanisms by coordinating the expression of resistance genes, when CAMPs are detected at the cell surface. TCSs are typically composed of a membrane histidine kinase (HK), acting as a signal sensor/transducer, through phosphorylation of its cognate response PLoS ONE | www.plosone.org 1 July 2011 | Volume 6 | Issue 7 | e21323

×