NuGO has initiated the development of the Phenotype Database (dbNP). This database is developed together with several other consortia (e.g. Netherlands Metabolomics Centre) and is currently used within several European projects, such as Food4me, NU-AGE, Bioclaims and Nutritech.
The Phenotype Database (www.dbnp.org) is a web-based application/database that can store any biological study. We used this application to perform an analysis on a combination of several studies with the objective to test if it is possible to answer new research questions using a ‘virtual cohort’.
The assessment of the health status of an individual is an important but challenging issue. Nowadays, challenge tests are proposed as a method to assess and quantify health status. We would like to find mechanistic explanations for differences in clinical subgroups and to develop a metabolomics platform based fingerprint at baseline that represents important parameters of the challenge test. Currently, there is not one single study available that includes enough subjects from specific clinical subgroups to develop such a fingerprint or study the biological processes specific for those subgroups. Therefore, we developed a toolbox that facilitates the combined analysis of multiples studies.