Photonic and optic technologies with potential for health applications. Prof  Ben Eggleton, School of Physics
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Photonic and optic technologies with potential for health applications. Prof Ben Eggleton, School of Physics

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Photonic and optic technologies with potential for health applications. Prof  Ben Eggleton, School of Physics Photonic and optic technologies with potential for health applications. Prof Ben Eggleton, School of Physics Presentation Transcript

  • IPOS - Institute of Photonics and Optical Science Prof. Ben Eggleton, ARC Laureate Director, Institute of Photonics and Optical Science (IPOS) Fellow Director, CUDOS ARC Centre of Excellence School of Physics http://sydney.edu.au/ipos/
  • Photonics: Critical enabling science › Photonics is the science and technology of generating, controlling and detecting photons (began with the invention of the laser 53 years ago)
  • Introduction to IPOS IPOS Institute of Photonics and Optical Science “To provide Australia with the innovation, scientists and engineers to maintain and enhance a position of worldleadership in photonics, in academia and industry.” › ~100 Members from the - School of Physics, incl. - CUDOS – Sydney, Astrophotonics, Quantum - Electrical Engineering - Fibre-optics and photonics laboratory - School of Chemistry - Interdisciplinary Photonics Laboratories - Molecular Spectroscopy & Photonics - School of Mathematics and Statistics › 55 Researchers › 35 Research Students FPL Fibre-optics & Photonics Laboratory
  • Research IPOS Institute of Photonics and Optical Science › Diverse research areas Ultrafast photonics Quantum photonics Communications Astrophotonics Optical fibre technology Nonlinear optics High power & mid-IR lasers Integrated and nanophotonics Microfluidics Biomedical photonics Renewable energy Defence photonics Molecular spectroscopy Optical sensing Microwave and Terahertz
  • Fibre Biomedical Photonics › Microstructured Polymer Optical Fibre - Holes provide guiding, and sensitivity › Unique capability at University of Sydney › Inexpensive to access through ANFF › PMMA (Perspex) - Extremely low cost – disposable sensors - Biocompatible / non-hazardous › “Lab in fibre” - Ultrasensitive molecular detection - Picolitre volumes - Long interaction lengths › But also - On Body (non-invasive), and - In Body (invasive) sensing / interfacing opportunities…
  • Fibre Biomedical Devices › Non-invasive Sensing - Fibre - sensitive to temperature, bending, pressure… - Example: Heart rate monitor, integrated with PPE -> - Potential: Fibre combined with bandage, could provide long term, continuous, inexpensive pressure monitoring, including remotely. - Also monitor heart-rate, blood pressure, or physical exertion. › Invasive Interfacing - Neural interface – channels for: - Electrical: detection and stimulation - Chemical: drug delivery - Optical: optogenetic detection and stimulation - Developed for neuroscience research J. Witt et al, POF 2011 Bilbao (Spain) Conference Proceedings – SENSORS II
  • Optofluidics: Photonics + Microfluidics Optical channel: Light constrained on the micron scale Microfluidic channel: Fluid constrained on the micron scale Microfluidics + microphotonics Flexible optical systems at the microscopic scale Source: http://www.optofluidicscorp.com/ • C. Monat, P. Domachuk, B. J. Eggleton, “Optlofludics”, Nature Photonics 2012 • V. Oncescu, et al, “Smartphone based health accessory for colorimetric detection of biomarkers in sweat and saliva,” Lab on a Chip 13, 3232 (2013) • A. Casas-Bedoya, et al, “Chip scale humidity sensing based on a microfluidic infiltrated photonic crystal,” Appl. Phys. Lett. 103, 181109 (2013); • H. Schmidt et al “Photonic integration of nonsolid media using optofluidics. Nat. Phot, 5, 598 (2011). Erickson/Cornell
  • Silk photonics Biocompatibility Biologically favourable carrier that allows biodopants to maintain their function while held within its crystalline matrix with remarkable robustness • • • • • S. Kim, et al “Silk inverse opals,” Nat. Phot. 6, (2012). P. Domachuk, et al. “Bioactive ‘self-sensing’ optical systems.,” Appl. Phys. Lett. 95, 253702 (2009). F. G. Omenetto, “Bioactive silk protein biomaterial systems for optical devices,” Biomacromolecules 9, 1214 (2008). S.T. Parker, P. Domachuk, et al. “Biocompatible silk printed optical waveguides,” Adv. Mater. 21, 2411–2415 (2009). H Perry, F.G, Gopinath, ”Nano- and micropatterning of optically transparent, mechanically robust, biocompatible silk fibroin films,”. Adv. Mater. 20, 3070–3072 (2008).
  • Photonics at the University of Sydney Australian Institute of Nanoscience (AIN) -10,500 m2 building -600 m2 clean room (nanolithography) -Photonics a key driver (1 floor of labs) -Interdisciplinary focus
  • Photonics at the University of Sydney Australian Institute of Nanoscience (AIN) -10,500 m2 building -600 m2 clean room (nanolithography) -Photonics a key driver (1 floor of labs) -Interdisciplinary focus