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EWMA 2013 - Ep555 - Negatively Charged Microspheres- (NCM) Technology for The Treatment of Post Aesthetic Surgery Complications

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Josef Haik MD MPH, Eyal Winkler MD, Nimrod Farber MD, Moti Harats MD, Oren Weissman MD …

Josef Haik MD MPH, Eyal Winkler MD, Nimrod Farber MD, Moti Harats MD, Oren Weissman MD

Department of Plastic and Reconstructive Surgery and The Burn Unit, Sheba Medical Center
ISRAEL

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  • 1. Negatively Charged Microspheres Technology for the Treatment of Post Aesthetic Surgery Complications Josef Haik MD MPH, Eyal Winkler MD, Nimrod Farber MD, Moti Harats MD, Oren Weissman MD Department of Plastic and Reconstructive Surgery and The Burn Unit, Sheba Medical Center ISRAEL
  • 2. Background • Complications following aesthetic procedures such as lower T-junction wound dehiscence following breast reduction surgery, or flap necrosis following a facelift procedure are vexing and grievous complications both to the patient and the surgeon. • Treatment modalities that can actively expedite wound healing and re-epithelialization rates are highly craved. • Objectives - To assess wound healing and re- epithelialization rates of open wounds due to dehiscence following breast reduction surgery or flap necrosis following a facelift procedure.
  • 3. Methods • Eight patients with wounds of the aforementioned types (5 breast reduction patients and 3 facelift patients) were treated with daily dressing with NCM soaked dressings. • Wound closure rates were documented daily.
  • 4. Results • Treatment duration averaged 10 days in the facelift cases and 33 days for breast cases. • Wounds showed both accelerated granulation tissue formation, and re-epithelialization rates. • Average wound epithelialization rate was 1.9 millimeters per day for breast cases and 1 millimeters per day for the facelift cases. • In these cases, NCM treatment helped patients avoid additional surgery such as skin grafting. No complications or side effects were encountered.
  • 5. Patient’s Results • Female, 29 year old • Wound etiology: Post bilateral breast reduction, postoperative wound dehiscence • Wound duration: 29 days • Previous treatment: Povidone iodine soaked dressings, AG hydrofiber dressings Prior to treatment Day 5 of treatment Day 12 of treatment Day 24 of treatment
  • 6. Patient’s Results • Female, 52 year old • Wound etiology: Post bilateral breast reduction, postoperative wound dehiscense • Wound duration: 19 days • Previous treatment: Silver sulfadiazine, AG hydrofiber dressings Prior to treatment Day 5 of treatment Day 10 of treatment Day 17 of treatment
  • 7. Patient’s Results• Female, 31 year old • Wound etiology: Post unilateral facelift due to regressed hemangioma, postoperative flap necrosis • Wound duration: 32 days • Previous treatment: Silver sulfadiazine, surgical debridement, AG hydrofiber dressings Prior to treatment 1 Week of treatment 2 Weeks of treatment
  • 8. Discussion • CPM may offer a new and efficacious way to expedite the healing of open wounds of various etiologies, including resistant wounds that failed to heal despite deploying a multitude of treatment modalities including surgery. • CPM seems to expedite both the formation of granulation tissue (including over bones, cartilages and tendons) as well as epithelialization rates. • Further research with larger patient volumes are still needed to verify these findings.