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Research Report 
Issue 27 • September 2014 
FEATURED: Research Decisions 
Research Decisions 
2 Become a participant 
and help us with our 
research 
3 How we decide 
on which research 
proposals we fund 
Our Insights 
4 A new treatment 
for a form of 
breast cancer 
Help Us 
4 Register to 
join one of our 
research studies 
There are times when the stoicism of countrymen is a 
weakness. Not seeking or following medical advice is 
just such a time. 
Cancer Council 13 11 20 
cancercouncil.com.au 
How to reduce the risk 
of death from prostate 
cancer, especially if you 
live in rural Australia 
A recent study found that men living in 
regional areas have a lower survival rate for 
prostate cancer than city dwellers. 
Over the 15 years of the study, if survival rates in rural areas were 
the same as those in the city then there would have been 700 
fewer deaths from prostate cancer. 
“Until we have real evidence regarding why this is the case, there 
are many things that rural men can do to help themselves”, said 
Associate Professor David Smith, “because as our population ages and grows more men will be living with prostate cancer.” 
What men who are over 50 and live in rural areas need to do 
• Talk to their GPs about testing for prostate cancer, 
• If they are diagnosed with prostate cancer they should actively seek specialists who can help them find the best 
treatment and follow-up that is practical and manageable given the distances they may have to travel, 
• Ensure they are regularly monitored. 
The role of Cancer Council NSW 
Cancer Council encourages men in rural areas to see their doctors regularly, and to discuss prostate cancer. We are also 
working to increase the level of awareness among peak bodies of the inequity of survival rates between men who live in 
the city and those who live in regional and rural areas. And we want research to be funded to explain the disparity. 
Our aim is to ensure that all men have the best possible chance of beating prostate cancer regardless of where they live or 
how much they earn. 
For further information on prostate cancer visit: www.cancercouncil.com.au or call the Cancer Council Helpline on 13 11 20. 
Honorary doctorate awarded to Sally 
Crossing, founder of Cancer Voices 
She was instrumental in ensuring that consumers’ views 
were included at every stage in cancer research 
Sally Crossing was awarded an Honorary Doctorate in Health Sciences by the 
University of Sydney in recognition of her “extraordinary leadership and contribution 
to supporting those with cancer from diagnosis, through treatment, care, support and 
survivorship in both advocacy and research”.
We need you, especially if you are male 
You can also register at cancercouncil.com.au/joinastudy 
A new scholarship to 
use CLEAR Study data 
funded by supporters of 
Outrun Cancer 
Cancer Council 13 11 20 
cancercouncil.com.au 
Would you be willing to 
help us with our research? 
The more participants we get to help with our 
research the more we need 
Join a Research Study (JRS) is a database of participants with and 
without cancer who are keen to take part in research programs 
conducted by Cancer Council NSW and other academic bodies. 
JRS collects contact details and a little health information, and then 
puts participants in contact with researchers. The research programs 
may be questionnaire based surveys, focus group, telephone 
interviews or other types of research. 
With the number of participants on our database growing to around 2,500 more 
and more researchers from all over Australia have asked to use our data, so we 
need more and more participants. 
Men are noticeably more elusive than women when it comes to participating in 
research studies, so they are a priority for JRS. We need more men to join our 
database, both those who have cancer as well as those who haven’t. 
If you would be willing to help us, please fill in and mail the form on the back page, 
or complete the consent form and questionnaire online. 
Give 5 
minutes to 
beat cancer. 
Luca Turrini and the supporters of Outrun Cancer have raised 
the funding for a PhD student scholarship to research the role 
of exercise, body mass index, diet and other similar factors in 
emerging cancers, using the data obtained from the CLEAR 
Outrun Cancer supporters raise funds at sponsored 
Study and other related studies. 
corporate treadmill marathons 
Corporate treadmill marathons organised by Outrun Cancer have 
been the source of the funds. “What started as a tribute to my mother, has now grown into a fulfilling way of life and a commitment 
to make a real difference and contribution to really, OUTRUN cancer,” said Luca Turrini, founder of the cancer prevention charity. 
The treadmill marathons show we can all do 
something to bring the defeat of cancer closer 
For more information, visit clearstudy.org.au 
Join a research study ►
How we select the research 
that we fund 
Members of the community work hard to raise money for 
cancer research and this gives them a right to a voice in 
deciding on which projects it is spent 
Other than government, Cancer Council NSW invests more on cancer research in 
Australia than any other organisation. 
Around 150 applications for research grants are submitted each year and we 
select about 15 of them to fund. That selection process involves assessing both 
the scientific merit of a project and its potential value to the community. To reach 
a decision on which proposals to fund involves consideration and evaluation by 
professional scientists as well as informed member of the community. 
The process works like this 
In 2013, our Consumer Review Panel consisted of six men and six women from across metropolitan and regional NSW, 
representing a range of cancer experiences. The panel included survivors and carers of oesophageal cancer, prostate 
cancer, breast cancer and leukaemia. The 2014 Consumer Review Panel will hold their first meeting in October. 
For more information, visit cancercouncil.com.au/research/ 
Cancer Council NSW Research Report Issue 27 • September 2014 
Researchers send their research 
proposals to Cancer Council NSW. 
The proposals are assessed by panels 
of scientists. The panels give each 
proposal a score, based on the quality 
of the science. 
Cancer Council NSW considers only 
the top-ranked proposals, which 
ensures that all the research we fund is 
scientifically rigorous. 
The top-ranked proposals are assessed 
by our Consumer Review Panel. This 
is a group of specially trained cancer 
survivors, carers and family members. 
They judge each proposal according to 
its value to the community. This panel 
gives each proposal a score based on 
its likely benefits and impact. 
The scores assigned to each proposal 
by the scientific and consumer panels 
are combined to create a final ranking 
of proposals. 
Funding is awarded based on the 
final rankings. The Cancer Research 
Committee, a committee of 
international cancer research leaders, 
oversees this process to ensure 
good governance and the best use of 
community donations. 
9.2 
8.9 9.0 9.3
At last, there’s a 
potential treatment 
for triple negative 
breast cancer 
A new treatment has been developed 
from many years of studying cancer 
cells in the laboratory 
Breast cancers are the most common cancer in 
women. Years of research have led to innovative 
treatments and high survival rates, with the exception 
of one particular type of breast cancer that is both 
aggressive and difficult to treat—triple negative breast 
cancer. 
It is called ‘triple negative’ breast cancer because there are 
very low amounts of three important cell proteins (estrogen 
and progesterone receptors, and HER2) which makes them 
unresponsive to common breast cancer therapies that work 
by ‘attacking’ these proteins. 
Triple negative breast cancer is more common among 
younger women. It grows and spreads quickly and to date has 
not had a targeted treatment. 
Professor Robert Baxter and his team from Kolling Institute 
of Medical Research, University of Sydney have potentially 
developed a treatment for triple negative breast cancer that 
combines drugs already used for other diseases. They found 
that the two drug therapies in combination could significantly 
slow or even stop the growth of the type of breast cancer. 
And as both drugs are already used with human patients, the 
For more information, visit: cancercouncil.com.au 
Breast cancer Bowel cancer Melanoma Lung cancer Uterine cancer 43+21+15+14+7 2,000 
Neither drug was effective on its own, only when they combined the two 
drugs did they find they stopped the cancer spreading 
new treatment could move quickly from the laboratory to the 
clinic, without the lengthy delays and huge costs involved in 
developing new drugs. 
Most commonly diagnosed cancers in women in 2012 
16,000 
14,000 
12,000 
10,000 
8,000 
8,000 
4,000 
0 
AIHW, Cancer in Australia: an overview 2012 
Help 
us beat 
cancer 
Register to 
join a research 
study today! 
Cancer Council and other academic bodies conduct 
research studies to do with cancer. These studies may 
be questionnaire based surveys, focus groups and 
interviews or other types of research. Study participants 
will not necessarily be cancer patients. 
Register your interest to be included on our database. 
Your story or the story of someone you know will help us 
find the answers. 
Yes, include me on the database. (If yes, we will 
write to ask you some additional questions relating 
to your health to allow us to match you to research 
studies that suit you.) 
Tick this box if you have been diagnosed with 
cancer in the past 18 months. (If yes, you may be 
eligible for the CLEAR Study and we will send you 
further information.) 
Title* 
First Name* 
Last Name* 
Address* 
Town* 
Postcode* 
Email 
Phone 
Mobile 
* Mandatory 
CAN 2030 09/14 
Return completed form to: 
Reply Paid 79819 
Potts Point, NSW 1335 
You can also register at cancercouncil.com.au/joinastudy 
At Cancer Council we recognise the importance of your privacy and the safeguarding of your personal information. If you have concerns about the privacy of this information, you may provide it securely online at cancercouncil.com.au/joinastudy. Please be 
assured that in collecting this information, it will be used for research purposes only, and will be handled in accordance with our Privacy Management Plan (www.cancercouncil.com.au) which addresses our compliance with all legislative requirements.

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Cancer Council NSW Research Report Newsletter Sept 2014

  • 1. Research Report Issue 27 • September 2014 FEATURED: Research Decisions Research Decisions 2 Become a participant and help us with our research 3 How we decide on which research proposals we fund Our Insights 4 A new treatment for a form of breast cancer Help Us 4 Register to join one of our research studies There are times when the stoicism of countrymen is a weakness. Not seeking or following medical advice is just such a time. Cancer Council 13 11 20 cancercouncil.com.au How to reduce the risk of death from prostate cancer, especially if you live in rural Australia A recent study found that men living in regional areas have a lower survival rate for prostate cancer than city dwellers. Over the 15 years of the study, if survival rates in rural areas were the same as those in the city then there would have been 700 fewer deaths from prostate cancer. “Until we have real evidence regarding why this is the case, there are many things that rural men can do to help themselves”, said Associate Professor David Smith, “because as our population ages and grows more men will be living with prostate cancer.” What men who are over 50 and live in rural areas need to do • Talk to their GPs about testing for prostate cancer, • If they are diagnosed with prostate cancer they should actively seek specialists who can help them find the best treatment and follow-up that is practical and manageable given the distances they may have to travel, • Ensure they are regularly monitored. The role of Cancer Council NSW Cancer Council encourages men in rural areas to see their doctors regularly, and to discuss prostate cancer. We are also working to increase the level of awareness among peak bodies of the inequity of survival rates between men who live in the city and those who live in regional and rural areas. And we want research to be funded to explain the disparity. Our aim is to ensure that all men have the best possible chance of beating prostate cancer regardless of where they live or how much they earn. For further information on prostate cancer visit: www.cancercouncil.com.au or call the Cancer Council Helpline on 13 11 20. Honorary doctorate awarded to Sally Crossing, founder of Cancer Voices She was instrumental in ensuring that consumers’ views were included at every stage in cancer research Sally Crossing was awarded an Honorary Doctorate in Health Sciences by the University of Sydney in recognition of her “extraordinary leadership and contribution to supporting those with cancer from diagnosis, through treatment, care, support and survivorship in both advocacy and research”.
  • 2. We need you, especially if you are male You can also register at cancercouncil.com.au/joinastudy A new scholarship to use CLEAR Study data funded by supporters of Outrun Cancer Cancer Council 13 11 20 cancercouncil.com.au Would you be willing to help us with our research? The more participants we get to help with our research the more we need Join a Research Study (JRS) is a database of participants with and without cancer who are keen to take part in research programs conducted by Cancer Council NSW and other academic bodies. JRS collects contact details and a little health information, and then puts participants in contact with researchers. The research programs may be questionnaire based surveys, focus group, telephone interviews or other types of research. With the number of participants on our database growing to around 2,500 more and more researchers from all over Australia have asked to use our data, so we need more and more participants. Men are noticeably more elusive than women when it comes to participating in research studies, so they are a priority for JRS. We need more men to join our database, both those who have cancer as well as those who haven’t. If you would be willing to help us, please fill in and mail the form on the back page, or complete the consent form and questionnaire online. Give 5 minutes to beat cancer. Luca Turrini and the supporters of Outrun Cancer have raised the funding for a PhD student scholarship to research the role of exercise, body mass index, diet and other similar factors in emerging cancers, using the data obtained from the CLEAR Outrun Cancer supporters raise funds at sponsored Study and other related studies. corporate treadmill marathons Corporate treadmill marathons organised by Outrun Cancer have been the source of the funds. “What started as a tribute to my mother, has now grown into a fulfilling way of life and a commitment to make a real difference and contribution to really, OUTRUN cancer,” said Luca Turrini, founder of the cancer prevention charity. The treadmill marathons show we can all do something to bring the defeat of cancer closer For more information, visit clearstudy.org.au Join a research study ►
  • 3. How we select the research that we fund Members of the community work hard to raise money for cancer research and this gives them a right to a voice in deciding on which projects it is spent Other than government, Cancer Council NSW invests more on cancer research in Australia than any other organisation. Around 150 applications for research grants are submitted each year and we select about 15 of them to fund. That selection process involves assessing both the scientific merit of a project and its potential value to the community. To reach a decision on which proposals to fund involves consideration and evaluation by professional scientists as well as informed member of the community. The process works like this In 2013, our Consumer Review Panel consisted of six men and six women from across metropolitan and regional NSW, representing a range of cancer experiences. The panel included survivors and carers of oesophageal cancer, prostate cancer, breast cancer and leukaemia. The 2014 Consumer Review Panel will hold their first meeting in October. For more information, visit cancercouncil.com.au/research/ Cancer Council NSW Research Report Issue 27 • September 2014 Researchers send their research proposals to Cancer Council NSW. The proposals are assessed by panels of scientists. The panels give each proposal a score, based on the quality of the science. Cancer Council NSW considers only the top-ranked proposals, which ensures that all the research we fund is scientifically rigorous. The top-ranked proposals are assessed by our Consumer Review Panel. This is a group of specially trained cancer survivors, carers and family members. They judge each proposal according to its value to the community. This panel gives each proposal a score based on its likely benefits and impact. The scores assigned to each proposal by the scientific and consumer panels are combined to create a final ranking of proposals. Funding is awarded based on the final rankings. The Cancer Research Committee, a committee of international cancer research leaders, oversees this process to ensure good governance and the best use of community donations. 9.2 8.9 9.0 9.3
  • 4. At last, there’s a potential treatment for triple negative breast cancer A new treatment has been developed from many years of studying cancer cells in the laboratory Breast cancers are the most common cancer in women. Years of research have led to innovative treatments and high survival rates, with the exception of one particular type of breast cancer that is both aggressive and difficult to treat—triple negative breast cancer. It is called ‘triple negative’ breast cancer because there are very low amounts of three important cell proteins (estrogen and progesterone receptors, and HER2) which makes them unresponsive to common breast cancer therapies that work by ‘attacking’ these proteins. Triple negative breast cancer is more common among younger women. It grows and spreads quickly and to date has not had a targeted treatment. Professor Robert Baxter and his team from Kolling Institute of Medical Research, University of Sydney have potentially developed a treatment for triple negative breast cancer that combines drugs already used for other diseases. They found that the two drug therapies in combination could significantly slow or even stop the growth of the type of breast cancer. And as both drugs are already used with human patients, the For more information, visit: cancercouncil.com.au Breast cancer Bowel cancer Melanoma Lung cancer Uterine cancer 43+21+15+14+7 2,000 Neither drug was effective on its own, only when they combined the two drugs did they find they stopped the cancer spreading new treatment could move quickly from the laboratory to the clinic, without the lengthy delays and huge costs involved in developing new drugs. Most commonly diagnosed cancers in women in 2012 16,000 14,000 12,000 10,000 8,000 8,000 4,000 0 AIHW, Cancer in Australia: an overview 2012 Help us beat cancer Register to join a research study today! Cancer Council and other academic bodies conduct research studies to do with cancer. These studies may be questionnaire based surveys, focus groups and interviews or other types of research. Study participants will not necessarily be cancer patients. Register your interest to be included on our database. Your story or the story of someone you know will help us find the answers. Yes, include me on the database. (If yes, we will write to ask you some additional questions relating to your health to allow us to match you to research studies that suit you.) Tick this box if you have been diagnosed with cancer in the past 18 months. (If yes, you may be eligible for the CLEAR Study and we will send you further information.) Title* First Name* Last Name* Address* Town* Postcode* Email Phone Mobile * Mandatory CAN 2030 09/14 Return completed form to: Reply Paid 79819 Potts Point, NSW 1335 You can also register at cancercouncil.com.au/joinastudy At Cancer Council we recognise the importance of your privacy and the safeguarding of your personal information. If you have concerns about the privacy of this information, you may provide it securely online at cancercouncil.com.au/joinastudy. Please be assured that in collecting this information, it will be used for research purposes only, and will be handled in accordance with our Privacy Management Plan (www.cancercouncil.com.au) which addresses our compliance with all legislative requirements.