Supplements 101 wisconsin leukemia and lymphoma society sept 2013 final

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A Closer Look at Supplements and Your Health September 18, 2013 …

A Closer Look at Supplements and Your Health September 18, 2013
Craig Peterson, N.D. MSA LAc.
Naturopathic Resident
Cancer Treatment Centers of America

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  • 4 year, doctoral-level Naturopathic Medical schoolFederally accredited by the Council on Naturopathic Medical Education, 7 schools including the U.S. and CanadaPassed rigorous professional board examsSame 2 year basic sciences as an MDAdditional training in Clinical Nutrition, Homeopathic Medicine, Botanical Medicine, Psychology, and CounselingTrained to use prescription drugs, although emphasis is placed on the use of natural healing agents.Perform minor surgeries – removing cysts, stitching up superficial wounds. Do not practice major surgery.
  • Vitamin B12 DeficiencyMegaloblastic anemia, fatigue, weakness, constipation, loss of appetite and weight loss.Neurological changes – numbness and tingling in hands and feet, balance issues.Other symptoms – depression, confusion, dementia, poor memory, and soreness of the mouth or tongue
  • low potential for toxicity
  • NeuropathyVit B6 – oxaliplatin - http://www.ncbi.nlm.nih.gov/pubmed/20976600; http://www.ncbi.nlm.nih.gov/pubmed/18754531L Glutamine - http://www.ncbi.nlm.nih.gov/pubmed/15997923Alpha lipoic acid - http://www.ncbi.nlm.nih.gov/pubmed/22331979Acetyl l Carnitine - http://www.ncbi.nlm.nih.gov/pubmed/17696592CardioEssential Fatty Acid –CAD - http://www.ncbi.nlm.nih.gov/pubmed/7702027?dopt=AbstractCoQ10CHF - http://www.ncbi.nlm.nih.gov/pubmed/8241697?dopt=AbstractHTN - http://www.ncbi.nlm.nih.gov/pubmed/7752851?dopt=AbstractL Carnitine http://www.ncbi.nlm.nih.gov/pubmed/23597877HawthorneCHF - http://www.ncbi.nlm.nih.gov/pubmed/12040357?dopt=AbstractHTN - http://www.ncbi.nlm.nih.gov/pubmed/12043949?dopt=AbstractInteractions - http://www.ncbi.nlm.nih.gov/pubmed/12043949?dopt=Abstract
  • DigestiveProbiotics - http://www.ncbi.nlm.nih.gov/pubmed/2398194;ibs - http://www.ncbi.nlm.nih.gov/pubmed/23981066L glutamine – diarrhea - http://www.ncbi.nlm.nih.gov/pubmed/22705427Slippery elm – ibs - http://www.ncbi.nlm.nih.gov/pubmed/?term=slippery+elm+bark+and+diarrrheaMusculoskeletalBromelain - http://www.ncbi.nlm.nih.gov/pubmed/18482869; http://www.ncbi.nlm.nih.gov/pubmed/19727022Curcumin - http://www.ncbi.nlm.nih.gov/pubmed/23347846Magnesium – tetany - http://www.ncbi.nlm.nih.gov/pubmed/17660621; cramps - http://www.ncbi.nlm.nih.gov/pubmed/21289017Calcium – osteoperosis - http://www.ncbi.nlm.nih.gov/pubmed/23636543
  • Curcumin - http://www.ncbi.nlm.nih.gov/pubmed/23985704; http://www.ncbi.nlm.nih.gov/pubmed/22185211Green tea - http://www.ncbi.nlm.nih.gov/pubmed/21419224; http://www.ncbi.nlm.nih.gov/pubmed/18087282Vitamin D3 – aml - http://www.ncbi.nlm.nih.gov/pubmed/23974111Resveratrol – leukemia - http://www.ncbi.nlm.nih.gov/pubmed/23597602Sulforaphane - http://www.ncbi.nlm.nih.gov/pubmed/23251470
  • Melatonin - http://www.ncbi.nlm.nih.gov/pubmed/8462731 Mushroom -

Transcript

  • 1. A Closer Look at Supplements and Your Health September 18, 2013 Craig Peterson, N.D. MSA LAc. Naturopathic Resident Cancer Treatment Centers of America®
  • 2. Disclaimer • All material provided today is for informational and educational purposes only, and is not intended to provide you with medical advice. • This presentation is not a substitute for medical care nor is it a substitute for consultation with a healthcare professional. Please discuss all medical and nutrition questions with your health care provider. © 2013 Rising Tide 2
  • 3. Principles of Naturopathic Medicine • The Healing Power of Nature • Identify and Treat the Cause(s) • First Do No Harm • Doctor as Teacher • Treat the Whole Person • Prevention © 2013 Rising Tide 3
  • 4. What is a Naturopathic Physician? • Licensed naturopathic physician (ND) ― 4 year, doctoral-level Naturopathic Medical school; federally accredited ― Same 2 year basic sciences as an MD with additional training in Clinical Nutrition, Homeopathic Medicine, Botanical Medicine, Psychology, and Counseling ― Trained to use prescription drugs ― Perform minor surgeries – removing cysts, stitching up superficial wounds. Do not practice major surgery. © 2013 Rising Tide 4
  • 5. Naturopathic Medicine - Licensure © 2013 Rising Tide 5 http://www.aanmc.org/images/LicensureMapBig_Up dateJune2013.jpg
  • 6. Main Topics • Supplements 101 • Vitamin B12 o What is it? o What are the benefits? o When is it indicated? • Managing Side Effects o How to utilize supplements to ease side effects? © 2013 Rising Tide 6
  • 7. Supplements - Overview • Definition • Purpose • Categories – Vitamins – Minerals – Herbs • Cautions © 2013 Rising Tide 7
  • 8. Supplements - Definition Dietary Supplement Health and Education Act (DSHEA) Dietary supplement: – Intended to supplement the diet – Contains one or more dietary ingredients (including vitamins, minerals, herbs or other botanicals, amino acids, and certain other substances) or their constituents – Intended to be taken by mouth, in forms such as tablet, capsule, powder, softgel, gelcap, or liquid – Labeled as being a dietary supplement © 2013 Rising Tide 8
  • 9. Federal Regulation • The regulations for dietary supplements are not the same as those for prescription or over-the-counter drugs. • Manufacturers of dietary supplements are responsible for ensuring that their products are safe and that the label information is truthful and not misleading. • However, a manufacturer of a dietary supplement does not have to provide the FDA with data that demonstrate the safety of the product before it is marketed. © 2013 Rising Tide 9
  • 10. Purpose of Dietary Supplements • Added to the diet to boost overall health & energy • Provide immune system support and reduce the risks of illness and age-related conditions • Improve performance in athletic and mental activities • Support the healing process during illness and disease © 2013 Rising Tide 10
  • 11. Categories of Dietary Supplements • Vitamins • Minerals • Herbal/ Botanical © 2013 Rising Tide 11
  • 12. Vitamins • Vitamins are micronutrients – substances the body uses in small amounts • The body requires vitamins to support its basic biochemical functions • Deficiencies over time can lead to illness and disease © 2013 Rising Tide 12
  • 13. Water & Fat Soluble Vitamins • Water-soluble vitamins dissolve in water and pass through the body quickly, meaning that the body needs them on a regular basis. • Fat-soluble vitamins are stored in the body's fatty tissue, meaning that they remain in the body longer. • Water-soluble vitamins include the B-complex and vitamin C. • Fat-soluble vitamins include vitamins A, D, E, and K. © 2013 Rising Tide 13
  • 14. What happened to the alphabet? Where is F-J? © 2013 Rising Tide 14 Vitamin A Vitamin B1 Vitamin B2 Vitamin B3 Vitamin B5 Vitamin B6 Vitamin B7 Vitamin B9 Vitamin B12 Vitamin C Vitamin D Vitamin E Vitamin K
  • 15. Minerals • Minerals are micronutrients and are essential for the proper functioning of the body. • Cells in the body require minerals as part of their basic make-up and chemical balance. © 2013 Rising Tide 15
  • 16. Bulk & Trace Minerals • Minerals can either be bulk minerals, used by the body in larger quantities, or trace minerals, used by the body in minute or trace amounts. • Bulk minerals include sodium, potassium, calcium, magnesium, and phosphorus. • Trace minerals include iron, zinc, selenium, iodine, chromium, copper, mangane se, and others. © 2013 Rising Tide 16
  • 17. How Much Vitamin and Mineral is Needed? • The U.S. government has published recommended dietary allowances (RDAs) for each vitamin and mineral for the general population. – These figures can be used as guidelines – Individuals may have different needs depending on gender, age, and health conditions. • http://ods.od.nih.gov/factsheets/list-VitaminsMinerals/ • http://fnic.nal.usda.gov/ © 2013 Rising Tide 17
  • 18. Herbs - Botanical • Herbal supplements are added to the diet for both nutritional and medicinal purposes. • Herbs can supplement the diet to aid in overall health or to stimulate healing for specific conditions. • The medicinal effects of herbs are gaining scientific validation; some pharmaceuticals have been derived directly from plant sources – Aspirin (found in willow bark), – Codeine (from poppy seeds), – Paclitaxel -Taxol (from the Pacific Yew tree) © 2013 Rising Tide 18
  • 19. Importance of Supplement Safety • What to look for? – Authenticity – Purity – Potency • Supplement Certification Groups – USP (U.S. Pharmacopeial) – NSF (National Science Foundation) – NNFA GMP (National Nutritional Foods Association Good Manufacturing Practices) © 2013 Rising Tide 19
  • 20. Key Points • To use dietary supplements safely, read and follow the label instructions, and recognize that “natural” does not always mean “safe.” • Some dietary supplements may interact with medications or pose risks if you have medical problems or are going to have surgery. • Most dietary supplements have not been tested in pregnant women, nursing mothers, or children. © 2013 Rising Tide 20
  • 21. Vitamin B12 © 2013 Rising Tide 21
  • 22. Vitamin B12 – What is it? • Water soluble vitamin • Contains the mineral cobalt – “Cobalamins” – Methylcobalamin and 5-deoxyadenosylcobalamin • Foods that contain B12 – commonly found in fish, shellfish, meat, eggs, and dairy products. © 2013 Rising Tide 22
  • 23. Vitamin B12 - What are the benefits? • Required for proper red blood cell formation and hemoglobin synthesis • Required for neurological function • DNA synthesis • Acts as a cofactor Fat and Protein metabolism © 2013 Rising Tide 23
  • 24. Vitamin B12 - When is it indicated? • Pernicious anemia • Gastrointestinal – Celiac and Crohn’s disease • Vegetarians • Cardiovascular disease – Hyperhomocysteinemia • Dementia and cognitive function • Fatigue © 2013 Rising Tide 24
  • 25. Dietary B12 Supplements • Cyanocobalamin  converted to Methylcobalamin + 5-deoxyadenosylcobalamin in the body. • Supplemental types: ― Oral ― Sublingual ― Injection (intramuscular) ― Intranasal gel (prescription) • Absorption is largely limited by intrinsic factor. © 2013 Rising Tide 25
  • 26. Vitamin B12 - Cautions • Upper Limit has not been established • Interactions with medications: – Chloramphenicol (Chloromycetin) – Proton Pump Inhibitors (PPI) • Omeprazole (Prilosec) • lansoprazole (Prevacid) – H2 receptor antagonist • Cimetidine (Tagamet) • famotidine (Pepcid) • ranitidine (Zantac) – Metformin © 2013 Rising Tide 26
  • 27. How do I utilize nutrients and supplements to help manage side effects? – Fatigue • B Complex • Astragalus • Ginseng – Infection • Vitamin C • Elderberry Syrup © 2013 Rising Tide 27 This content is for informational and educational purposes only, and is not intended to provide medical advice or to be a substitute for medical care or consultation with a healthcare professional. Please discuss all medical and nutrition questions with your health care provider.
  • 28. Managing Side Effects continued… – Neuropathy • Vitamin B6 • L-Glutamine • Alpha lipoic acid • Acetyl L carnitine – Cardiovascular wellness • Essential Fatty Acids • Coenzyme Q10 • L-Carnitine • Hawthorne (Crataegus) © 2013 Rising Tide 28 This content is for informational and educational purposes only, and is not intended to provide medical advice or to be a substitute for medical care or consultation with a healthcare professional. Please discuss all medical and nutrition questions with your health care provider.
  • 29. Managing Side Effects continued… – Digestive • Probiotics • L-Glutamine • Slippery elm – Musculoskeletal • Bromelain • Curcumin • Magnesium • Calcium © 2013 Rising Tide 29 This content is for informational and educational purposes only, and is not intended to provide medical advice or to be a substitute for medical care or consultation with a healthcare professional. Please discuss all medical and nutrition questions with your health care provider.
  • 30. Anti-Cancer Properties – Curcumin – Green Tea Extract (EGCG) – Vitamin D3 – Resveratrol – Sulforaphanes © 2013 Rising Tide 30 This content is for informational and educational purposes only, and is not intended to provide medical advice or to be a substitute for medical care or consultation with a healthcare professional. Please discuss all medical and nutrition questions with your health care provider.
  • 31. Avoid in Hematologic Malignancies • Immune stimulating – Melatonin – Medicinal Mushroom Extract • Reishi, • Turkey Tail • Shitake © 2013 Rising Tide 31 This content is for informational and educational purposes only, and is not intended to provide medical advice or to be a substitute for medical care or consultation with a healthcare professional. Please discuss all medical and nutrition questions with your health care provider.
  • 32. • QUESTIONS? © 2013 Rising Tide 32
  • 33. THANK YOU! • Wisconsin Naturopathic Physician Association • WNPA • www.wisconsin-nd.org • Oncology Association of Naturopathic Physician • OncANP • www.oncanp.org © 2013 Rising Tide 33
  • 34. References • PubMed • Uptodate • Natural Medicine Comprehensive Database • Natural Standard • http://ods.od.nih.gov/factsheets/list-VitaminsMinerals/ • http://fnic.nal.usda.gov/ © 2013 Rising Tide 34